Patents by Inventor Xudong Ye

Xudong Ye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250197952
    Abstract: A transgenic soybean event, Gm_CSM63717, is provided. Transgenic plant cells, plant parts, plants, seeds, progeny plants, and agricultural and commodity products containing event Gm_CSM63717 are also provided. Recombinant DNA molecules unique to the event Gm_CSM63717, and methods of using and detecting Gm_CSM63717 are also provided. Soybean plants containing the event Gm_CSM63717 exhibit tolerance to PPO inhibitors.
    Type: Application
    Filed: December 6, 2024
    Publication date: June 19, 2025
    Inventors: Sarah Brown, Christine Ellis, Robert Gaeta, Zane Goodwin, Diane Hohorst, Clayton Tyler Larue, Linda Rymarquis, Xiaohong Shi, Janice Weihe, Xudong Ye
  • Patent number: 12331329
    Abstract: Provided are compositions for genome editing and site-directed integration in plants comprising microprojectile particles coated, treated of applied with a recombinant DNA construct comprising a sequence encoding one or more genome editing reagents for delivery to a mature embryo explant from dry seeds. Further provided are methods for genome editing and site-directed integration in at least one cell of a plant using the disclosed compositions, and plants, plant parts and seeds comprising an edited genome or site-directed integration, which are produced by the disclosed methods.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: June 17, 2025
    Assignee: Monsanto Technology LLC
    Inventors: Yurong Chen, Annie Saltarikos, Jianping Xu, Xudong Ye
  • Publication number: 20250137002
    Abstract: The present invention relates to methods and compositions for transforming soybean, corn. cotton, or canola explants using spectinomycin as a selective agent for transformation of the explants. The method may further comprise treatment of the explants with cytokinin during the transformation and regeneration process.
    Type: Application
    Filed: December 17, 2024
    Publication date: May 1, 2025
    Inventors: Brian J. Martinell, Michael W. Petersen, David A. Somers, Yuechun Wan, Edward Williams, Xudong Ye
  • Patent number: 12275944
    Abstract: This disclosure is related to plant-optimized recombinant nucleic acids encoding Cpf1 and their use in planta. Also disclosed are compositions, expression cassettes, and plant cells comprising the recombinant nucleic acids as well as methods and kits for modifying a target sequence in a plant genome using the recombinant nucleic acids.
    Type: Grant
    Filed: November 3, 2023
    Date of Patent: April 15, 2025
    Assignee: Monsanto Technology LLC
    Inventors: Stanislaw Flasinski, Elysia Krieger, Ervin Nagy, Krishnakumar Sridharan, Xudong Ye
  • Publication number: 20250051790
    Abstract: The present disclosure relates to compositions and methods for improving site-directed integration frequency in the genome of plant cells.
    Type: Application
    Filed: October 21, 2024
    Publication date: February 13, 2025
    Applicant: Monsanto Technology LLC
    Inventors: John BRADLEY, Larry A. GILBERTSON, Ervin NAGY, Christine SHYU, Peizhen YANG, Xudong YE
  • Patent number: 12195736
    Abstract: The present invention relates to methods and compositions for transforming soybean, corn, cotton, or canola explants using spectinomycin as a selective agent for transformation of the explants. The method may further comprise treatment of the explants with cytokinin during the transformation and regeneration process.
    Type: Grant
    Filed: October 5, 2023
    Date of Patent: January 14, 2025
    Assignee: Monsanto Technology LLC
    Inventors: Brian J. Martinell, Michael W. Petersen, David A. Somers, Yuechun Wan, Edward Williams, Xudong Ye
  • Patent number: 12157893
    Abstract: The present disclosure relates to compositions and methods for improving site-directed integration frequency in the genome of plant cells.
    Type: Grant
    Filed: November 10, 2021
    Date of Patent: December 3, 2024
    Assignee: Monsanto Technology LLC
    Inventors: John Bradley, Larry A. Gilbertson, Ervin Nagy, Christine Shyu, Peizhen Yang, Xudong Ye
  • Publication number: 20240301435
    Abstract: The invention provides novel compositions and methods for improving the transformation of monocot seed excised embryo explants, which may include one or more steps of explant preparation, explant rehydration, Rhizobiales bacterium inoculation and co-culture, bud induction, extended bud induction, or regeneration of genetically modified plants or plant parts. The methods provided herein may include transforming at least one plant cell of the embryo explant with a heterologous polynucleotide by inoculating the embryo explant with a Rhizobiales bacterium comprising the heterologous polynucleotide. The methods provided herein also include methods of regenerating a genetically modified plant or plant part from a transformed or edited plant cell or explant.
    Type: Application
    Filed: March 19, 2024
    Publication date: September 12, 2024
    Inventors: Justin Arsenault, Yurong Chen, Byung-Guk Kang, Jennifer Kumpf, Brian J. Martinell, Lorena B. Moeller, Mary Ann Saltarikos, Ashok Shrawat, Shubha Subbarao, Edward J. Williams, Xudong Ye
  • Publication number: 20240229063
    Abstract: A transgenic corn event, Zm_CSM63715, is provided. Transgenic plant cells, plant parts, plants, seeds, progeny plants, and agricultural and commodity products containing event Zm_CSM63715 are also provided. Recombinant DNA molecules unique to the event Zm_CSM63715, and methods of using and detecting Zm_CSM63715 are also provided. Corn plants containing the event Zm_CSM63715 exhibit tolerance to PPO inhibitors.
    Type: Application
    Filed: December 15, 2023
    Publication date: July 11, 2024
    Inventors: Matthew Bauer, Sarah Brown, Robert Thomas Gaeta, Michael Edward Goley, Shirley Guo, Erin Lyn Hall, Andrei Kouranov, Clayton Tyler Larue, Mingsheng Peng, Linda Rymarquis, Oscar Cornelius Sparks, JR., Xudong Ye
  • Publication number: 20240200086
    Abstract: This disclosure is related to plant-optimized recombinant nucleic acids encoding Cpf1 and their use in planta. Also disclosed are compositions, expression cassettes, and plant cells comprising the recombinant nucleic acids as well as methods and kits for modifying a target sequence in a plant genome using the recombinant nucleic acids.
    Type: Application
    Filed: November 3, 2023
    Publication date: June 20, 2024
    Applicant: Monsanto Technology LLC
    Inventors: Stanislaw FLASINSKI, Elysia KRIEGER, Ervin NAGY, Krishnakumar SRIDHARAN, Xudong YE
  • Publication number: 20240117366
    Abstract: The present invention relates to methods and compositions for transforming soybean, corn, cotton, or canola explants using spectinomycin as a selective agent for transformation of the explants. The method may further comprise treatment of the explants with cytokinin during the transformation and regeneration process.
    Type: Application
    Filed: October 5, 2023
    Publication date: April 11, 2024
    Inventors: Brian J. Martinell, Michael W. Petersen, David A. Somers, Yuechun Wan, Edward Williams, Xudong Ye
  • Publication number: 20240093222
    Abstract: The present invention provides methods for the production of viable explants from mature corn seeds, wherein the explant comprises the apical portion of the embryo axis of the corn seed. The present invention also relates to methods for producing such explants and for transforming the explants with a heterologous DNA.
    Type: Application
    Filed: October 3, 2023
    Publication date: March 21, 2024
    Inventors: Yurong Chen, Brian J. Martinell, Anatoly Rivlin, Ashok Shrawat, Yuechun Wan, Edward J. Williams, Xudong Ye
  • Publication number: 20240035039
    Abstract: Recombinant DNA molecules and constructs are provided that are useful for modulating gene expression in plants. One or more expression cassette(s) of a recombinant DNA molecule or construct may be excised from transgenic plants following transformation by the presence of flanking site-specific recombination sites in the recombinant DNA molecule or construct by expression of a recombinase enzyme encoded by the recombinant DNA molecule or construct. Such a recombinase system may be used to remove such expression cassette(s) from plants transformed with the recombinant DNA construct or vector. The recombinase transgene may be operably linked to a tissue-preferred or tissue-specific promoter for autoexcision in transformed plants without crossing to a different transgenic line expressing the recombinase.
    Type: Application
    Filed: October 19, 2021
    Publication date: February 1, 2024
    Inventors: PokChun Jennifer To, Zrir Vaghchhipawala, Xudong Ye
  • Patent number: 11859191
    Abstract: This disclosure is related to plant-optimized recombinant nucleic acids encoding Cpf1 and their use in planta. Also disclosed are compositions, expression cassettes, and plant cells comprising the recombinant nucleic acids as well as methods and kits for modifying a target sequence in a plant genome using the recombinant nucleic acids.
    Type: Grant
    Filed: August 3, 2022
    Date of Patent: January 2, 2024
    Assignee: Monsanto Technology LLC
    Inventors: Stanislaw Flasinski, Elysia Krieger, Ervin Nagy, Krishnakumar Sridharan, Xudong Ye
  • Publication number: 20230383301
    Abstract: The present disclosure is in the field of plant transformation. The disclosure provides methods for increasing the rate of site-directed integration of a sequence of interest in plants. The disclosure also provides methods for increasing the efficiency of Rhizobiales-mediated plant transformation.
    Type: Application
    Filed: June 6, 2023
    Publication date: November 30, 2023
    Inventors: Elysia K. KRIEGER, Richard J. LAWRENCE, Zarir E. VAGHCHHIPAWALA, Jianping XU, Xudong YE
  • Patent number: 11807846
    Abstract: The present invention provides methods for the production of viable explants from mature corn seeds, wherein the explant comprises the apical portion of the embryo axis of the corn seed. The present invention also relates to methods for producing such explants and for transforming the explants with a heterologous DNA.
    Type: Grant
    Filed: April 29, 2012
    Date of Patent: November 7, 2023
    Assignee: Monsanto Technology LLC
    Inventors: Yurong Chen, Brian J. Martinell, Anatoly Rivlin, Yuechun Wan, Edward J. Williams, Xudong Ye, Ashok Shrawat
  • Patent number: 11807858
    Abstract: The present invention relates to methods and compositions for transforming soybean, corn, cotton, or canola explants using spectinomycin as a selective agent for transformation of the explants. The method may further comprise treatment of the explants with cytokinin during the transformation and regeneration process.
    Type: Grant
    Filed: December 10, 2020
    Date of Patent: November 7, 2023
    Assignee: MONSANTO TECHNOLOGY LLC
    Inventors: Brian J. Martinell, Michael W. Petersen, David A. Somers, Yuechun Wan, Edward Williams, Xudong Ye
  • Patent number: 11732268
    Abstract: The present disclosure is in the field of plant transformation. The disclosure provides methods for increasing the rate of site-directed integration of a sequence of interest in plants. The disclosure also provides methods for increasing the efficiency of Rhizobiales-mediated plant transformation.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: August 22, 2023
    Assignee: Monsanto Technology LLC
    Inventors: Elysia K. Krieger, Richard J. Lawrence, Zarir E. Vaghchhipawala, Jianping Xu, Xudong Ye
  • Patent number: 11713465
    Abstract: The present invention provides methods for the transformation of viable explants from wheat seeds to permit production of transgenic wheat plants. The present invention also relates to methods for producing such explants and related embodiments.
    Type: Grant
    Filed: November 21, 2014
    Date of Patent: August 1, 2023
    Assignee: MONSANTO TECHNOLOGY, LLC
    Inventors: David R. Duncan, Sarah Heifner, David Kelm, Brian J. Martinell, Lorena Moeller, Anatoly Rivlin, Rebecca Rode, Xudong Ye, Ashok Shrawat, Yurong Chen
  • Publication number: 20230193302
    Abstract: This disclosure is related to plant-optimized recombinant nucleic acids encoding Cpfl and their use in planta. Also disclosed are compositions, expression cassettes, and plant cells comprising the recombinant nucleic acids as well as methods and kits for modifying a target sequence in a plant genome using the recombinant nucleic acids.
    Type: Application
    Filed: August 3, 2022
    Publication date: June 22, 2023
    Applicant: Monsanto Technology LLC
    Inventors: Stanislaw FLASINSKI, Elysia KRIEGER, Ervin NAGY, Krishnakumar SRIDHARAN, Xudong YE