Abstract: This application discloses a mobile device and method for managing installation of an application package (APK) in the mobile device. The device receives an installation request for installing the APK. The device retrieves a permission certificate for the APK according to the installation request. The permission certificate includes a cryptographic signature. The device determines validity of the permission certificate by verifying the cryptographic signature included in the permission certificate using a permission certification public key provided by a manufacturer of the device. The permission certification public key is stored in the device. The installation of the APK in the device is allowed when the permission certificate is determined to be valid. Using the method, the APK requires the device to grant specific high-risk permissions to the application upon installation.

Abstract: This application discloses a mobile device and method for managing installation of an application package (APK) in the mobile device. The device receives an installation request for installing the APK. The device retrieves a permission certificate for the APK according to the installation request. The permission certificate includes a cryptographic signature. The device determines validity of the permission certificate by verifying the cryptographic signature included in the permission certificate using a permission certification public key provided by a manufacturer of the device. The permission certification public key is stored in the device. The installation of the APK in the device is allowed when the permission certificate is determined to be valid. Using the method, the APK requires the device to grant specific high-risk permissions to the application upon installation.

Abstract: This application discloses a mobile device and method for managing installation of an application package (APK) in the mobile device. The device receives an installation request for installing the APK. The device retrieves a permission certificate for the APK according to the installation request. The permission certificate includes a cryptographic signature. The device determines validity of the permission certificate by verifying the cryptographic signature included in the permission certificate using a permission certification public key provided by a manufacturer of the device. The permission certification public key is stored in the device. The installation of the APK in the device is allowed when the permission certificate is determined to be valid. Using the method, the APK requires the device to grant specific high-risk permissions to the application upon installation.

Abstract: This document discloses a system and method for verifying system integrity of an electronic device. The electronic device includes a verifier device provided within a secure environment of the electronic device and a scanner device provided within a normal environment of the electronic device whereby the secure environment comprises hardware that is isolated from the hardware in the normal environment, i.e. these two environments are hardware isolated.

Abstract: This application discloses a mobile device and method for managing installation of an application package (APK) in the mobile device. The device receives an installation request for installing the APK. The device retrieves a permission certificate for the APK according to the installation request. The permission certificate includes a cryptographic signature. The device determines validity of the permission certificate by verifying the cryptographic signature included in the permission certificate using a permission certification public key provided by a manufacturer of the device. The permission certification public key is stored in the device. The installation of the APK in the device is allowed when the permission certificate is determined to be valid. Using the method, the APK requires the device to grant specific high-risk permissions to the application upon installation.

Abstract: This document discloses a system and method for verifying system integrity of an electronic device. The electronic device includes a verifier device provided within a secure environment of the electronic device and a scanner device provided within a normal environment of the electronic device whereby the secure environment comprises hardware that is isolated from the hardware in the normal environment, i.e. these two environments are hardware isolated.

Abstract: Embodiments of the application provide a mobile device architecture having non-protected environment and one or more protected containers for isolating application programs and application data according to their sensitivity or privacy levels. Access policy and exception policy are defined for each protected container to limit access to application program and data associated with or stored in the protected container(s). A communication monitor module is provided to implement the access and exception policy, and manage communication in the mobile device, including intra-container communication, inter-container communication and communication to and from the non-protected environment.

Abstract: The present invention provides methods of promoting the revascularization and/or reenervation of central nervous system lesions using an in-situ crosslinkable hydrogel. The present invention also provides methods of treating a spinal cord injury by topically delivering to the spinal cord injury site a vehicle comprising a neurotrophic factor and/or anti-inflammatory agent. Also provided are methods of treating a spinal cord injury by topically administering or delivering a hydrogel to the injury site.

Abstract: The present invention provides a synthetic cell culture platform, comprising: a two dimensional and/or three dimensional surface comprising peptides conjugated to said surface and methods of using the platform for increasing cell adhesion, stable attachment and/or proliferation of cells grown on the platform and for promoting differentiation of neural stem cells into neurons.

Abstract: Medical devices with a plastic albumin body with a defined three dimensional shape that are particularly suitable for pressure equalization tubes. The plastic albumin body can be a unitary substantially monolithic body of albumin. The plastic albumin body has an antibacterial property such that it is resistant to bacterial adhesions and/or bacterial biofilm formation thereon. Methods and processes are described for forming a consolidated protein-based coating on an implant, and coated implants produced therefrom, with improved biocompatibility, nonthrombogenity and antimicrobiality that are suitable for various medical implants and drug delivery devices, such as bone implants, catheters, cannuale, guide wires, stents, shunts, vascular grafts, heart valves, heart and ventricular assist devices, oxygenators, dialyzers, medical devices, and other substrates, such as furniture, keyboards, etc.

Abstract: Disclosed are methods of forming three dimensional arrays of aligned nanofibers in an open, loose structure of any desired depth. The arrays are formed according to an electrospinning process utilizing two parallel conducting plates to align the fibers and rotating tracks to distribute the fibers throughout the array. Arrays can be used as formed, for instance in tissue engineering applications as three dimensional scaffolding constructs. As-formed arrays can be combined with other materials to form a composite 3-D structure. For instance, composite polymeric materials can be electrospun to form composite nanofibers within the array. Multiple polymeric materials can be electrospun at different areas of the array to form a composite array including materially different nanofibers throughout the array. The arrays can be loaded with other fibrous or non-fibrous materials to form a composite array. Arrays can also be rolled to form a uniaxial fiber bundle.

Abstract: The present invention provides a synthetic cell culture platform, comprising: a two dimensional and/or three dimensional surface comprising peptides conjugated to said surface and methods of using the platform for increasing cell adhesion, stable attachment and/or proliferation of cells grown on the platform and for promoting differentiation of neural stem cells into neurons.

Abstract: The present invention provides methods of promoting the revascularization and/or reenervation of central nervous system lesions using an in-situ crosslinkable hydrogel.

Abstract: The present invention provides methods and compositions for tissue regeneration without cell transplantation.

Abstract: Disclosed are composite materials that can more closely mimic the mechanical characteristics of natural elastic tissue, such as vascular tissue. Disclosed materials include a combination of elastic nanofibers and non-elastic nanofibers. Also disclosed are a variety of methods for forming the composite materials. Formation methods generally include the utilization of electrospinning methods to form a fibrous composite construct including fibers of different mechanical characteristics.

Abstract: Disclosed are composite arrays and methods of forming the arrays. Composite arrays include a hydrogel-forming polymeric network and a network of electrospun fibers embedded within the polymeric network. For instance, the polymeric network can include one or more extracellular matrix proteins. The network of electrospun fibers can describe an open configuration that incorporates sufficient space between adjacent fibers to allow for cellular ingrowth between and among individual fibers. Disclosed composite arrays can be utilized as a supporting scaffold for living cells, for instance in development of bioengineered tissue constructs.

Abstract: The present invention provides methods of promoting the revascularization and/or reenervation of central nervous system lesions using an in-situ crosslinkable hydrogel.

Abstract: Disclosed are a series of kneadable, pliable polymers for use in forming compositions that can be used as bone wax or as a cellular scaffold. Polymers can include a polysaccharide backbone and can be biocompatible and thrombogenic. In addition, the compositions can be osteoconductive as well as biodegradable. The disclosed compositions can be used to help control bleeding from bone surfaces as well as to promote bone regeneration and fusion. The compositions can inhibit the growth of microorganisms in implantation sites and can be loaded with additional bioactive agents to further promote healing and infection prevention.

Abstract: The present invention provides methods and compositions for sequentially and separately reducing infection and/or inflammation and regenerating tissue at a lesion site, by contacting the lesion site with a biodegradable scaffold that first delivers one or more agents at the lesion site to reduce infection and/or inflammation and then delivers one or more agents to regenerate tissue at the lesion site after inflammation is reduced.