Abstract: Provided herein are certain isoindolinone compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.

Abstract: A novel aluminum-free humidity-regulating lining paper for cigarettes and a preparation method thereof are provided, where the lining paper comprises a base paper layer, a dense barrier layer, a hydrophobic functional layer, and a composite humidity-regulating layer. The dense barrier layer contains polyvinyl alcohol (PVA) and glycerol, the hydrophobic functional layer includes calcium stearate, a silane coupling agent (SCA), nanocellulose, and carboxymethyl cellulose (CMC), and the composite humidity-regulating layer comprises sodium alginate, nanoporous calcium silicate (NCS), glycerol, and hyaluronic acid. The hydrophobic functional layer, formed within a CMC matrix with nanocellulose as a physical cross-linking agent, benefits from a hydrophobic synergistic effect of calcium stearate and the SCA, providing hydrophobicity and barrier capacity without compromising the barrier properties of the PVA-based dense barrier layer under high humidity.

Abstract: The present disclosure relates to the technical field of tests, and in particular, to a thin test strip, a test strip roll, and an application of the thin test strip. The thin test strip includes: a waterproof top layer, a composite layer, and a waterproof bottom layer in sequence from top to bottom, where the composite layer includes a sample collection pad, a colloidal gold conjugate pad, a color developing membrane, and a sample absorption pad, the waterproof top layer does not cover the sample collection pad and completely covers the colloidal gold conjugate pad, the color developing membrane, and the sample absorption pad, and the composite layer is I-shaped. The waterproof top layer and the waterproof bottom layer are made from polyethylene terephthalate (PET) waterproof transparent membranes.

Abstract: The present invention provides a photosensitive glass material, including the following components in percentage by weight: 65-78% of SiO2; 2-12% of R2O; 5-15% of Li2O; 3-12% of Al2O3; 1.5-10% of ZrO2; 0.01-0.6% of CeO2; 0.01-0.8% of Ag2O, wherein Li2O/ZrO2 is 1.0-7.5, and the R2O is one or two of Na2O and K2O. By reasonable component design, the photosensitive glass material of the present invention has a lower dielectric loss, and photosensitive microcrystalline glass and a photosensitive microcrystalline glass product made therefrom also have lower dielectric losses, and can reduce transmission losses of electric signals of application terminals during use.

Abstract: Disclosed is an MMLV reverse transcriptase mutant. The present invention provides an MMLV reverse transcriptase mutant having mutations at amino acid residue positions 66 and 68 compared with the wild-type MMLV reverse transcriptase amino acid sequence set forth in SEQ ID NO. 2. The mutant retains the reverse transcriptase activity. The mutant features improved template conversion performance, improved non-template base addition performance, or improved thermal resistance. According to the present invention, MMLV reverse transcriptase mutants with improved template conversion performance compared with the wild type and improved non-template base addition performance or thermal stability are selected. The selected mutants are suitable for RNA sequencing using library preparation methods based on template conversion, such as Smart-Seq, nanopore sequencing, and 5? RACE, and can also be applied to RT-qPCR and the like.

Abstract: A glass with high thermal expansion coefficient and excellent thermal shock resistance, wherein the glass includes the following components by mole percentage: 55-80% of SiO2; 0-10% of B2O3; 0-10% of Al2O3; 2-20% of ZnO; 0-15% of MgO; and no more than 30% of Li2O+Na2O+K2O. Through the reasonable proportioning of components, the glass has high thermal expansion coefficient and excellent thermal shock resistance at the same time. The glass is suitable for chemical strengthening, and the glass product obtained after chemical strengthening has large surface stress and large depth of stress layer.

Abstract: A focus-sensitive metrology target may be formed and read-out by a fabrication tool. A resulting overlay signal may be translated into a focus offset by comparison to a previously-determined calibration curve. One or more translated signals may be fed back to the fabrication tool for focus correction or used for prediction of on-device overlay (correction of overlay metrology results). In one embodiment, focus and overlay may be measured using a single target, where one portion of the target is formed on a first layer and includes a focus-sensitive design, and where another portion of the target is formed on a second layer and includes a relatively less focus-sensitive design. In some embodiments, a relative difference in focus response may be used to estimate an impact of focus error on device overlay and calculate non-zero offset contributions.

Abstract: Provided herein are certain compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.

Abstract: Embodiments of the present disclosure provide an energy storage system in thermal power unit coordinated frequency regulation control method, including: obtaining a status of an combined system of energy storage system and thermal power unit at a certain time point; determining a working period of the combined system according to the status of the combined system; determining a target active power of the combined system according to the working period of the combined system, and determining a target active power of the energy storage system according to the target active power of the combined system in cooperation with an active power of the thermal power unit; and correcting the target active power of the energy storage system according to a power limit and a capacity limit of the energy storage system, to obtain a final active power of the energy storage system.

Abstract: Embodiments of the present disclosure provide a datum selection method for minimizing hole position errors in group hole machining of large components, comprising: 1) determining a type of a computer numerical control (CNC) machine tool and establishing a topological structure of the CNC machine tool; 2) establishing a theoretical postural model of a tool center point during a motion; 3) establishing a hole position error model; 4) establishing an average error model of hole positions in group hole machining; and 5) obtaining a machining datum for group holes of corresponding components. For the skeleton and skinned group hole machining of aircraft components, different principles of datum selection are provided respectively, which can effectively improve the positional accuracy of the skeleton or skinned group hole machining, at the same time provides a more scientific and reasonable approach for the datum selection in group hole machining of large components.

Abstract: Embodiments of the present disclosure provide a datum selection method for minimizing hole position errors in group hole machining of large components, comprising: 1) determining a type of a computer numerical control (CNC) machine tool and establishing a topological structure of the CNC machine tool; 2) establishing a theoretical postural model of a tool center point during a motion; 3) establishing a hole position error model; 4) establishing an average error model of hole positions in group hole machining; and 5) obtaining a machining datum for group holes of corresponding components. For the skeleton and skinned group hole machining of aircraft components, different principles of datum selection are provided respectively, which can effectively improve the positional accuracy of the skeleton or skinned group hole machining, at the same time provides a more scientific and reasonable approach for the datum selection in group hole machining of large components.

Abstract: Provided is a data driving circuit and a display panel. The data driving circuit is configured to output a data signal for image display to multiple pixel units so as to drive the pixel units to display images. The data drive circuit includes a voltage regulating unit and multiple constant-current driving units, where the constant-current driving unit is configured to output a drive current corresponding to a data signal to at least one pixel unit. The voltage regulating unit is electrically connected to the multiple constant-current driving units and is configured to detect a driving current output by each constant-current driving unit and obtain a detection signal, and control the driving current output by each constant-current driving unit to be within a preset range according to the detection signal. The driving current output by each constant-current driving unit is adjusted.

Abstract: A microcrystalline glass product. The microcrystalline glass product includes the following components in percentage by weight: SiO2: 45-70%; Al2O3: 8-18%; Li2O: 10-25%; ZrO2: 5-15%; P2O5: 2-10%; and Y2O3: greater than 0 but less than or equal to 8%. Through reasonable component design, the microcrystalline glass and the microcrystalline glass product have excellent mechanical and optical properties and are suitable for electronic devices or display devices.

Abstract: A microcrystalline glass and microcrystalline glass product with excellent mechanical properties, microcrystalline glass product, the components of which, expressed in weight percent, contain: SiO2: 65˜80%; Al2O3: below 5%; Li2O: 10˜25%; ZrO2: 5˜15%; P2O5: 1˜8%. Through the reasonable component design, the microcrystalline glass product has excellent mechanical properties.

Abstract: The present invention provides a microcrystalline glass and microcrystalline glass product with excellent mechanical properties, microcrystalline glass product, the components of which, expressed in weight percent, contain: SiO2: 65 ?80%; AI2O3: below 5%; Li2O: 10 ?25%; ZrO2: 5 ?15%; P2O5: 1 ?8%. Through the reasonable component design, the microcrystalline glass product obtained by the present invention have excellent mechanical properties.

Abstract: Provided in this disclosure are methods for the synthesis of substituted 2-arylcyclopropylamines and 2-heteroarylcyclopropylamines and related compounds. Also provided are methods for reduction of thioesters to aldehydes, and methods for reductive amination of cyclopropylamines.

Abstract: A focus-sensitive metrology target may be formed and read-out by a fabrication tool. A resulting overlay signal may be translated into a focus offset by comparison to a previously-determined calibration curve. One or more translated signals may be fed back to the fabrication tool for focus correction or used for prediction of on-device overlay (correction of overlay metrology results). In one embodiment, focus and overlay may be measured using a single target, where one portion of the target is formed on a first layer and includes a focus-sensitive design, and where another portion of the target is formed on a second layer and includes a relatively less focus-sensitive design. In some embodiments, a relative difference in focus response may be used to estimate an impact of focus error on device overlay and calculate non-zero offset contributions.

Abstract: The present invention provides a microcrystalline glass product. The microcrystalline glass product includes the following components in percentage by weight: SiO2: 45-70%; Al2O3: 8-18%; Li2O: 10-25%; ZrO2: 5-15%; P2O5: 2-10%; and Y2O3: greater than 0 but less than or equal to 8%. Through reasonable component design, the microcrystalline glass and the microcrystalline glass product obtained in the present invention have excellent mechanical and optical properties and are suitable for electronic devices or display devices.