Patents by Inventor Y. Tom Tang

Y. Tom Tang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and Materials Relating to CD84-like Polypeptides and Polynucleotides
    Publication number: 20090042199
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: April 10, 2008
    Publication date: February 12, 2009
    Applicant: NUVELO, INC.
    Inventors: Chiaoyun Kuo, Bryan J. Boyle, Jian-Rui Wang, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Methods and Materials Relating to CD84-like Polypeptides and Polynucelotides
    Publication number: 20090023659
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: August 20, 2008
    Publication date: January 22, 2009
    Applicant: NUVELO, INC.
    Inventors: Chiaoyun Kuo, Bryan J. Boyle, Jian Rui Wang, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides
    Publication number: 20080306004
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted stem cell growth factor-like polypeptides. In particular, the invention relates to novel stem cell growth factor-like polypeptides, including novel proteins named SCGF3248Fk081_aa2, SCGF3248Fk081_aa1, SCGFFk081_aa3, and SCGF323401Fe131_aa1. Other aspects of the invention include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: February 11, 2008
    Publication date: December 11, 2008
    Applicant: Nuvelo, Inc.
    Inventor: Y. Tom Tang
  • Gastrointestinal proliferative factor and uses thereof
    Publication number: 20080300183
    Abstract: The invention relates to pharmaceutical compositions comprising gastrointestinal proliferative factor (GIPF) polynucleotides and polypeptides. The invention further relates to the therapeutic use of GIPF to prevent or treat conditions or disorders associated with the degeneration of the epithelial mucosa.
    Type: Application
    Filed: May 24, 2007
    Publication date: December 4, 2008
    Inventors: Bryan J. Boyle, Walter Funk, Makoto Kakitani, Takeshi Oshima, Eun Ju Park, Y. Tom Tang, Mikio Yagi, Kazuma Tomizuka
  • Methods and Materials Relating to CD84-like Polypeptides and Polynucleotides
    Publication number: 20080260747
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: April 10, 2008
    Publication date: October 23, 2008
    Applicant: NUVELO, INC.
    Inventors: Chiaoyun Kuo, Bryan J. Boyle, Jian-Rui Wang, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Stem cell factor-like proteins and uses thereof
    Patent number: 7439327
    Abstract: The invention relates to pharmaceutical compositions comprising gastrointestinal proliferative factor SCFA2, SCFA4 or SCFA4v polynucleotides and polypeptides. The invention further relates to the therapeutic use of SCFA2, SCFA4 or SCFA4v to prevent or treat conditions or disorders associated with the degeneration of the epithelial mucosa.
    Type: Grant
    Filed: January 17, 2006
    Date of Patent: October 21, 2008
    Assignee: Nuvelo, Inc.
    Inventors: Bryan J. Boyle, Peter C. R. Emtage, Walter Funk, Y. Tom Tang, Jingsong Zhao
  • Methods and materials relating to novel stem cell growth factor-like polypeptides and polynucleotides
    Publication number: 20080241882
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human stem cell growth factor-like protein. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human testis cells (Hyseq clone identification numbers 2880984 and 2881695), from human fetal skin (Hyseq clone identification number 15375176), adult spleen (Hyseq clone identification number 14856094), and human endothelial cells (Hyseq clone identification numbers 13804756, 13687487, 13804756). Other aspects of the invention include vectors containing processes fro producing novel human stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: November 16, 2007
    Publication date: October 2, 2008
    Inventors: Y. Tom Tang, Ivan Labat, Radoje T. Drmanac, Nancy Mize, Mitsuo Nishikawa, Cheng-Chi Chao
  • Methods and materials relating to novel stem cell growth factor-like polypeptides and polynucleotides
    Publication number: 20080241207
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human stem cell growth factor-like protein. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human testis cells (Hyseq clone identification numbers 2880984 and 2881695), from human fetal skin (Hyseq clone identification number 15375176), adult spleen (Hyseq clone identification number 14856094), and human endothelial cells (Hyseq clone identification numbers 13804756, 13687487, 13804756). Other aspects of the invention include vectors containing processes for producing novel human stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: November 19, 2007
    Publication date: October 2, 2008
    Inventors: Y. Tom Tang, Ivan Labat, Radoje T. Drmanac, Nancy Mize, Mitsuo Nishikawa, Cheng-Chi Chao
  • Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides
    Publication number: 20080227712
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted stem cell growth factor-like polypeptides. Other aspects of the invention include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: April 3, 2008
    Publication date: September 18, 2008
    Applicant: NUVELO, INC.
    Inventor: Y. Tom Tang
  • Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and DNA coding for the same
    Publication number: 20080227200
    Abstract: A gene encoding a polypeptide having an activity to support proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells is isolated by comparing expressed genes between cells which support proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells and cells which do not support the proliferation or survival. Proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells is supported by using stromal cells in which the isolated gene is expressed or a gene product of the isolated gene.
    Type: Application
    Filed: November 26, 2007
    Publication date: September 18, 2008
    Inventors: Radoje T. Drmanac, Ivan Labat, Y. Tom Tang, Juhi Lee, Birgit Stache-Crain, Mitsuo Nishikawa
  • Methods and materials relating to CD84-like polypeptides and polynucleotides
    Patent number: 7425610
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted CD84-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human spleen (Hyseq clone identification numbers 2938352 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted CD84-like polypeptides, and antibodies specific for such polyeptides.
    Type: Grant
    Filed: January 25, 2001
    Date of Patent: September 16, 2008
    Assignee: Nuvelo, Inc.
    Inventors: Chiaoyun Kuo, Bryan J. Boyle, Jian-Rui Wang, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides
    Publication number: 20080213839
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted stem cell growth factor-like polypeptides. Other aspects of the invention include vectors containing messes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: March 13, 2008
    Publication date: September 4, 2008
    Applicant: NUVELO, INC.
    Inventor: Y. Tom Tang
  • Stem cell factor-like proteins and uses thereof
    Publication number: 20080200388
    Abstract: The invention relates to pharmaceutical compositions comprising gastrointestinal proliferative factor SCFA2, SCFA4 or SCFA4v polynucleotides and polypeptides. The invention further relates to the therapeutic use of SCFA2, SCFA4 or SCFA4v to prevent or treat conditions or disorders associated with the degeneration of the epithelial mucosa.
    Type: Application
    Filed: April 1, 2008
    Publication date: August 21, 2008
    Applicant: NUVELO, INC.
    Inventors: Bryan J. Boyle, Peter C.R. Emtage, Walter Funk, Y. Tom Tang, Jingsong Zhao
  • Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides
    Patent number: 7411052
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted stem cell growth factor-like polypeptides. Other aspects of the invention include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: August 30, 2002
    Date of Patent: August 12, 2008
    Assignee: Nuvelo, Inc.
    Inventor: Y. Tom Tang
  • Polynucleotides encoding signal peptide-containing molecules
    Publication number: 20080187961
    Abstract: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
    Type: Application
    Filed: October 4, 2007
    Publication date: August 7, 2008
    Inventors: Preeti Lal, Y. Tom Tang, Gina A. Gorgone, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn, Ingrid E. Akerblom, Janice Au-Young, Henry Yue, Chandra Patterson, Roopa Reddy, Jennifer L. Hillman, Olga Bandman
  • Molecules associated with cell proliferation
    Publication number: 20080182977
    Abstract: The invention provides human molecules associated with cell proliferation (MACP) and polynucleotides which identify and encode MACP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of MACP.
    Type: Application
    Filed: March 27, 2008
    Publication date: July 31, 2008
    Inventors: Y. Tom Tang, Preeti Lal, Jennifer L. Hillman, Neil C. Corley, Chandra Arvizu, Mariah R. Baughn
  • Polynucleotides encoding molecules associated with cell proliferation
    Patent number: 7371832
    Abstract: The invention provides human molecules associated with cell proliferation (MACP) and polynucleotides which identify and encode MACP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of MACP.
    Type: Grant
    Filed: July 21, 1999
    Date of Patent: May 13, 2008
    Assignee: Incyte Corporation
    Inventors: Y. Tom Tang, Preeti Lal, Jennifer L. Hillman, Neil C. Corley, Chandra Arvizu, Mariah R. Baughn
  • Human phospholipases
    Patent number: 7368270
    Abstract: The invention provides human lipid metabolism enzymes (LME) and polynucleotides which identify and encode LME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LME.
    Type: Grant
    Filed: January 18, 2006
    Date of Patent: May 6, 2008
    Assignee: Incyte Corporation
    Inventors: Preeti Lal, Monique G. Yao, Henry Yue, Ameena R. Gandhi, Y. Tom Tang, Farrah A. Khan, Danniel B. Nguyen, Jennifer L. Policky, Debopriya Das, Jennifer L. Hillman, Narinder K. Walia, April J. A. Hafalia, Catherine M. Tribouley
  • Methods and materials relating to stem cell growth factor-like polypeptides and polynucleotides
    Publication number: 20080076715
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted stem cell growth factor-like polypeptides. In particular, the invention relates to novel stem cell growth factor-like polypeptides, including novel proteins named SCGF3248Fk081_aa2, SCGF3248Fk081_aa1, SCGFFk081_aa3, and SCGF323401Fe131_aa1. Other aspects of the invention include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: November 13, 2007
    Publication date: March 27, 2008
    Applicant: Nuvelo, Inc.
    Inventor: Y. Tom Tang
  • Novel nucleic acids and polypeptides
    Publication number: 20080050393
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: November 22, 2002
    Publication date: February 28, 2008
    Inventors: Y. Tom Tang, Vinod Asundi, Dennis Ballinger, Ivan Labat, Dena Leshkowitz, Jin Liu, Deborah Loeb, Julia R. Montgomery, Ann M. Pace, James P. Sheridan, Radoje T. Drmanac