Abstract: A concentrated solution of a polyglucosamine such as chitin or chitosan is prepared by forming an aqueous slurry of said polyglucosamine with a peroxide, and adding copper ion to said slurry so as to solubulize said polyglucosamine.

Abstract: Disease conditions which are dependent upon or moderated by angiogenesis are controlled by the use of a therapeutic material which interacts with cell surface galectins. Particular therapeutic materials comprise a polymeric backbone having side chains terminating in a sugar dependent therefrom. Disclosed are specific therapeutic materials in which the polymeric backbone is based upon polygalacturonic acid, and the side chains terminate in arabinose or galactose.

Abstract: Method and apparatus for tunneling operating codes to and from a call server in a packet network. A signaling package for the Megaco/H.248 protocol is provided which encapsulates or “tunnels” control and signaling codes for an endpoint device so that the codes can be communicated between a call server and the device. Only the call server and the endpoint device need have the intelligence to interpret the operating codes. Where the device is a programmable phone, the call server can be provisioned to understand and control specialized functions of the phone without adding new, telephone specific signaling to the standard Megaco/H.248 protocol for each type of phone to be supported. The media gateway that serves the specific telephone in question simply passes on any operating codes received.

Abstract: Method and apparatus for associating an end-to-end call identifier with a connection in a multimedia packet network. An end-to-end call identifier (EECID) is provided to uniquely identify a call leg across a packet network, regardless of the number of nodes used in completing the network path. The EECID allows for call association with a bearer connection so that high level call processing and low level bearer connection management can function independently but correlated by media gateways and media gateway controllers. Either a media gateway or media gateway controller can generate the EECID before establishing a connection for a call. The EECID is then sent to remote media gateways and media gateway controllers. The bearer connection can be setup by a media gateway at either end of the connection with respect to where the EECID is generated.

Abstract: The present invention is directed to methods and compositions for augmenting treatment of cancers and other proliferative disorders. In particular embodiments, the invention combines the administration of an agent that inhibits the anti-apoptotic activity of galectin-3 (e.g., a “galectin-3 inhibitor”) so as to potentiate the toxicity of a chemotherapeutic agent. In certain preferred embodiments, the conjoint therapies of the present invention can be used to improve the efficacy of those chemotherapeutic agents whose cytotoxicity is influenced by the status of an anti-apoptotic Bcl-2 protein for the treated cell. For instance, galectin-3 inhibitors can be administered in combination with a chemotherapeutic agent that interferes with DNA replication fidelity or cell-cycle progression of cells undergoing unwanted proliferation.

Abstract: Disease conditions which are dependent upon or moderated by angiogenesis are controlled by the use of a therapeutic material which interacts with cell surface galectins. Particular therapeutic materials comprise a polymeric backbone having side chains terminating in a sugar dependent therefrom. Disclosed are specific therapeutic materials in which the polymeric backbone is based upon polygalacturonic acid, and the side chains terminate in arabinose or galactose.

Abstract: The efficacy of conventional cancer therapies such as surgery, chemotherapy and radiation is enhanced by the use of a therapeutic material which binds to and interacts with galectins. The therapeutic material can enhance apoptosis thereby increasing the effectiveness of oncolytic agents. It can also inhibit angiogenesis thereby moderating tumor growth and/or metastasis.

Abstract: The efficacy of conventional cancer therapies such as surgery, chemotherapy and radiation is enhanced by the use of a therapeutic material which binds to and interacts with galectins. The therapeutic material can enhance apoptosis thereby increasing the effectiveness of oncolytic agents. It can also inhibit angiogenesis thereby moderating tumor growth and/or metastasis.

Abstract: The efficacy of conventional cancer therapies such as surgery, chemotherapy and radiation is enhanced by the use of a therapeutic material which binds to and interacts with galectins. The therapeutic material can enhance apoptosis thereby increasing the effectiveness of oncolytic agents. It can also inhibit angiogenesis thereby moderating tumor growth and/or metastasis.

Abstract: Methods and apparatus for negotiating bearer control parameters using property sets. A property set is a specific set of default parameters or “properties” to be used for a given bearer channel type in an integrated node. Property set information can be passed between integrated nodes (301, 302) in a multimedia packet network (305). In many cases, a parameter negotiation can be completed quickly after the originating node sends a setup message including a list of one or more property sets and one or more requested parameters. In all cases, the bearer type and bearer parameters are determined based on capabilities of the originating and terminating nodes. The invention provides a way for existing signaling links using bearer independent call control (BICC), or session initiation protocol (SIP), or H.245, or similar protocols with a way to negotiate more bearer types and parameters without significantly increasing the bandwidth needed for the negotiation, or requiring nodes to be provisioned.

Abstract: A rotary dryer. The dryer includes a rotary drum and a dehumidifier. the rotary cylinder receives dry air and wet material, wherein The wet material is rotated by the rotary drum to completely contact the dry air so that The wet material changes to grains. the dehumidifier receives wet air from the rotary drum, dehumidifies the wet air, and introduces dry air to the rotary cylinder.

Abstract: Disease conditions which are dependent upon or moderated by angiogenesis are controlled by the use of a therapeutic material which interacts with cell surface galectins. Particular therapeutic materials comprise a polymeric backbone having side chains terminating in a sugar dependent therefrom. Disclosed are specific therapeutic materials in which the polymeric backbone is based upon polygalacturonic acid, and the side chains terminate in arabinose or galactose.

Abstract: The efficacy of conventional cancer therapies such as surgery, chemotherapy and radiation is enhanced by the use of a therapeutic material which binds to and interacts with galectins. The therapeutic material can enhance apoptosis thereby increasing the effectiveness of oncolytic agents. It can also inhibit angiogenesis thereby moderating tumor growth and/or metastasis.

Abstract: An immune response in an organism is controlled by administering to said organism a therapeutically effective amount of a compound which binds to a galectin. In specific instances the compound is selected to bind to galectin-1 or galectin-3. Some therapeutic materials comprise natural or synthetic polymers having galactose or arabinose terminated side chains pendent therefrom. A group of preferred therapeutic compounds comprise modified pectins or other materials having a substantially demethoxylated rhamnogalacturan backbone having rhamnose residues interrupting the backbone. One therapeutic material includes a first functional portion which binds to the carbohydrate binding portion of a galectin, and a second functional portion which is operable to denature the galectin protein.

Abstract: According to the present invention, there is provided a gene therapy material which includes a nucleic acid material and a carbohydrate wherein the carbohydrate preferably is a modified pectin. Also in accordance with the present invention, there is provided a gene therapy material including a nucleic acid material, a carbohydrate material associated with the nucleic acid material, and a protective coating disposed about the carbohydrate material.

Abstract: A concentrated solution of a polyglucosamine such as chitin or chitosan is prepared by forming an aqueous slurry of said polyglucosamine with a peroxide, and adding copper ion to said slurry so as to solubulize said polyglucosamine.

Abstract: Computer telephone integration (CTI) server having dial-up network access. By providing increased integration between a CTI server and the public switched telephone network (PSTN), enhanced features can be provided to users of the CTI server for accessing on-line services. The server connects with on-line service providers either through a PSTN office or a dedicated data network which is associated with the PSTN. The dedicated data network is usually either a frame relay or an asynchronous transfer mode (ATM) network. The CTI server can also be connected to customer premises equipment (CPE) through a PSTN office to provide CTI services to dial-up users. Additionally, the CTI server can provide simultaneous access to multiple service providers which allows better integration of CTI services and services provided by Internet service providers.

Abstract: An in-process method and apparatus for monitoring and correcting or replacing a low pressure sensor that gives incorrect low pressure readings because of being contaminated or defective during the formation of integrated circuit structures in a low pressure chemical vapor deposition chamber, where deposition rates are a function of gas flow, temperature, and chamber pressure.

Abstract: An in-process method and apparatus for monitoring and correcting or replacing a low pressure sensor that gives incorrect low pressure readings because of being contaminated or defective during the formation of integrated circuit structures in a low pressure chemical vapor deposition chamber, where deposition rates are a function of gas flow, temperature, and chamber pressure.

Abstract: An in-process method and apparatus for monitoring and correcting or replacing a low pressure sensor that gives incorrect low pressure readings because of being contaminated or defective during the formation of integrated circuit structures in a low pressure chemical vapor deposition chamber, where deposition rates are a function of gas flow, temperature, and chamber pressure.