Abstract: The present invention relates to a thermally conductive silicone adhesive composition comprising: (A) an alkenyl group-containing organopolysiloxane; (B) an alkyl group-terminated organopolysiloxane; (C) a silane coupling agent; (D) a catalyst; and (E) a mixture of (e?1) alumina having a D50 particle size of 4 to 8 ?m, (e?2) silicon carbide having a D50 particle size of 1 to 4 ?m, and (e?3) alumina and/or zinc oxide having a D50 particle size less than 1 ?m, wherein the thermally conductive silicone adhesive composition exhibits a low thermal impedance, a low viscosity which is suitable for printing process, a high breakdown voltage, and a good anti-pump-out performance.

Abstract: This application discloses a method. The method includes: A terminal device obtains one or more measurement results respectively corresponding to one or more reference signals, and determines a CEL of the terminal device based on the one or more measurement results and at least one of N thresholds, where the N thresholds are a threshold 0, a threshold 1, . . . , and a threshold (N?1) in descending order. If there is a measurement result greater than or equal to the threshold 0 in the one or more measurement results, the CEL of the terminal device is a CEL 0. If the one or more measurement results are less than a threshold i, and there is a measurement result greater than or equal to a threshold (i+1), the CEL of the terminal device is a CEL (i+1), and a value of i is an integer from 0 to (N?2).

Abstract: The present disclosure relates to the technical field of natural product extraction, and particularly to a process for separating and extracting a nervonic acid from Xanthoceras sorbifolium Bunge. A preparation method thereof includes the following steps: extracting an Xanthoceras sorbifolium Bunge seed kernel to prepare Xanthoceras sorbifolium Bunge oil; refining the Xanthoceras sorbifolium Bunge oil by filtration through a composite polyethersulfone membrane and preparing a mixed fatty acid; and preparing a nervonic acid from the mixed fatty acid. In the present disclosure, molybdenum disulfide and hydrochloric acid-treated lithium fluoride are dispersed together in a solution. A composite polyethersulfone membrane obtained after treating a polyethersulfone membrane with a composite nanomaterial prepared by treatment with molybdenum disulfide and lithium fluoride, does not produce contamination and has an adsorption effect on an impurity in the Xanthoceras sorbifolium Bunge oil.

Abstract: Provided herein are certain fused multicyclic compounds with a multicyclic linker, such as a compound of Formula (I), as PARP1 inhibitors, pharmaceutical compositions comprising the compounds, and method of use of the compounds or pharmaceutical compositions in the treatment of diseases or disorders.

Abstract: Fiber-reinforced additively manufactured objects and associated systems and methods are provided herein. A method can include depositing a curable material. The method can further include applying first energy to the curable material to form an object portion on a build platform. The method can further include depositing a fiber onto or into the object portion, where the fiber is optically transparent and biocompatible. The method can further include applying second energy to the fiber to affix the fiber to the object portion.

Abstract: A method for configuring a transmission configuration without dynamic grant, includes: a terminal apparatus determines first information, where the first information indicates first configuration information of a first transmission configuration without dynamic grant; the terminal apparatus sends the first information to a first apparatus; and when a timer of the terminal apparatus expires, the terminal apparatus performs transmission without dynamic grant with the first apparatus based on the first configuration information of the first transmission configuration without dynamic grant.

Abstract: A method for configuring a transmission configuration without dynamic grant and a related apparatus. The method includes: a terminal apparatus receives downlink control information (DCI)/sidelink control information (SCI) sent by a first apparatus, where the DCI/SCI is used for retransmission and is used to configure a first transmission configuration without dynamic grant; and the terminal apparatus obtains first configuration information of the first transmission configuration without dynamic grant based on the DCI/SCI.

Abstract: Disclosed herein is a series of cyclic peptide PCSK9 inhibitors, along with methods of using the same and therapeutic applications thereof in the treatment of cardiovascular diseases, hypercholesterolemia, and related disorders.

Abstract: Provided is a method for manufacturing an optoelectronic device. The manufacturing method includes the following steps: In S1, a monolithic circuit board including multiple device units is manufactured. In S2, a chip is mounted on the first pad of the device unit, and the chip is electrically connected to the second pad so that a monolithic circuit board with the chip is obtained. In S3, the monolithic circuit board with the chip is encapsulated to obtain a monolithic optoelectronic device. In S4, the monolithic optoelectronic device is cut into individual optoelectronic devices. The method for manufacturing an optoelectronic device of the present disclosure can solve problems of substrate deformation and chips falling off and cracking during the manufacturing process of large-size and thin optoelectronic devices, thereby improving the yield rate.

Abstract: A system and method for endpoint detection is provided based on hyperspectral imaging technology and the exhaust gas chamber from a semiconductor processing chamber. The system includes a processing chamber that holds a substrate for processing. An exhaust gas line connects to an exhaust outlet of the processing chamber and directs exhaust gas to an exhaust chamber. A first RF power source connects to the exhaust chamber and generates an exhaust plasma from a portion of the exhaust gas within the exhaust chamber. A hyperspectral imaging (HSI) camera measures hyperspectral images of the exhaust plasma in the exhaust chamber. A method of processing the HSI images for endpoint detection is described.

Abstract: This application relates to an aerosol article and an aerosol-generating system. The aerosol article includes a protective layer, an aerosol substrate arranged inside the protective layer, a fixing component, and a heating component constrained and fixed within a substrate cavity by the fixing component. The heating component is configured to generate heat under an action of an electromagnetic field to heat the aerosol substrate and generate aerosol. An air channel communicating an interior with an exterior of the substrate cavity is formed on the fixing component or between the fixing component and the protective layer.

Abstract: The present disclosure provides an artificial flower, which includes a body provided with a hollow cavity, a driving part mounted in the hollow cavity, and a power member mounted on the body and configured to control a directional movement of the driving part along the hollow cavity; and through holes are formed in a side wall of the hollow cavity, and flowering branches pass through the through holes to be connected to the driving part.

Abstract: Disclosed herein are methods for manufacturing medical devices, such as implants, joint replacements, graft materials, augmentation materials, prosthetic materials, etc., from solid material reinforced curable resins. Methods of repositioning a patient's teeth using such medical devices are also provided.

Abstract: This application discloses a sensing method and a communication apparatus, to improve sensing performance. The method includes: A first communication apparatus determines first information, where the first information indicates a pulse repetition interval PRI. The first communication apparatus sends the first information to a second communication apparatus. Correspondingly, the second communication apparatus receives the first information from the first communication apparatus. The first information is used by the second communication apparatus to send a reference signal, and a periodicity of the reference signal in time domain is less than or equal to the PRI. The second communication apparatus sends the reference signal to the first communication apparatus based on the first information. Correspondingly, the first communication apparatus receives the reference signal from the second communication apparatus. The first communication apparatus senses a to-be-sensed target based on the reference signal.

Abstract: The present invention relates to a fructose diphosphate optical probe. Specifically, provided in the present invention is a fructose diphosphate optical probe, which comprises a fructose-1,6-diphosphate sensitive polypeptide and an optically active polypeptide, wherein the optically active polypeptide is located within the sequence of a fructose-1,6-diphosphate sensitive polypeptide, the fructose-1,6-diphosphate sensitive polypeptide is a fructose-1,6-diphosphate binding protein or a functional variant thereof, and the optically active polypeptide is a fluorescent protein or a functional variant thereof. The fluorescent probe of the present invention has a large dynamic change in terms of fluorescence and a good specificity, and can be used for high-throughput and quantitative detection of fructose diphosphate inside and outside a cell.

Abstract: Provided is a method for preparing ?-alanine, the method comprising: preparing a ?-alanine product from a reactant containing fumaric acid and aqueous ammonia in the presence of a catalyst, wherein the catalyst contains a catalyst composition containing aspartase and L-aspartic acid-?-decarboxylase, and adding fumaric acid during the reaction, wherein the total moles of the fumaric acid added is equal to the initial moles of the aqueous ammonia in the reactant minus the initial moles of the fumaric acid in the reactant. Also provided are methods for preparing a ?-alanine salt (in particular calcium ?-alanine, sodium ?-alanine, and potassium ?-alanine) and a pantothenate (in particular calcium pantothenate, sodium pantothenate, and potassium pantothenate).

Abstract: A hand-held refrigeration fan is provided, including a fan head and a hand-held portion. The fan head includes a fan housing, an air duct is formed in the fan housing, and the fan housing is provided with a connecting through hole penetrating through inner and outer sides of the air duct. A conductive member is arranged on an outer surface of the hand-held portion, a refrigeration apparatus is arranged in the hand-held portion, a refrigeration end of the refrigeration apparatus is connected to the conductive member in a heat conduction manner, and a heat dissipation end of the refrigeration apparatus communicates with the air duct after penetrating through the connecting through hole. A conductive sheet is arranged on an outer surface of a hand-held portion, and a refrigeration effect is achieved by the conductive sheet through the operation of a refrigeration apparatus.

Abstract: Provided are CD19 binding molecules, including anti-CD19 antibodies, including antibody fragments such as single-chain fragments, and chimeric receptors including the antibodies, such as chimeric antigen receptors (CARs). Among the antibodies are human antibodies, including those that compete for binding to CD19 with reference antibodies, such as murine antibodies. In some embodiments, the antibodies display similar functional properties to the reference antibodies, such as comparable binding affinities and/or competitive inhibition properties. Also provided are genetically engineered cells expressing the chimeric receptors, and uses of the binding molecules and cells adoptive cell therapy.

Abstract: Provided are a method for machining a device and the device. The method for machining a device includes die bonding, primary dicing, filling by a baffle wall material, grinding and secondary dicing. In the step of grinding machining, a semi-finished product is placed on a platform surface of a grinding and fixing platform, a grinding working end of a grinding device is controlled to operate, and with the platform surface of the grinding and fixing platform as a height reference, the grinding working end grinds from above the semi-finished product toward the grinding and fixing platform and operates to a preset height. Through the special machining process, the probability of the appearance of white glue on a top surface of the device is reduced, which is conducive to ensuring a production yield of the device.