Patents by Inventor Yan Chen

Yan Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12648834
    Abstract: Patterned dental positioning appliances including a shell having cavities shaped to receive and exert repositioning forces on one or more teeth of a subject's dentition. The shell may include a first cavity having a first raised pattern configured to exert a first force on a first tooth of the one or more teeth, and a second cavity having a second raised pattern configured to exert a second force on a second tooth of the one or more teeth. The second raised pattern may be different than the first raised pattern.
    Type: Grant
    Filed: April 8, 2024
    Date of Patent: June 9, 2026
    Assignee: Align Technology, Inc.
    Inventors: Chunhua Li, Yan Chen
  • Patent number: 12651216
    Abstract: A method in an illustrative embodiment includes determining, using a language model, a plurality of quantitative representations of a plurality of demands described in a natural language, and classifying the plurality of demands by clustering into a plurality of tasks based on the plurality of quantitative representations. The method further includes determining, using the language model, a quantitative representation of each task among the plurality of tasks and a quantitative representation of each agent among a plurality of agents, and assigning the plurality of tasks respectively to corresponding agents among the plurality of agents based on the quantitative representation of each task and the quantitative representation of each agent. In embodiments of the present disclosure, demand analysis and task assignment are performed on natural language demands by using a language model, which can achieve efficient matching between tasks and agents.
    Type: Grant
    Filed: May 28, 2024
    Date of Patent: June 9, 2026
    Assignee: Dell Products L.P.
    Inventors: Zijia Wang, Zhen Jia, Tianyu Ma, Guangliang Lei, Li Xie, Yan Chen
  • Publication number: 20260153029
    Abstract: Provided is a negative pressure air-seal induced system for controlling the environment of pipe jacking operation, including a turbulent airflow supply device provided at a certain distance from a tunnelling head and located in a tool pipe, wherein the turbulent airflow supply device forms an air curtain sealing structure at a certain angle with respect to the tunnelling head, the airflow rebounds and swirls between the air curtain and the tunnelling head to form an air turbulence vortex, so that the toxic and harmful gases are fully stirred and mixed to form a steady ascending airflow; and an exhaust device provided in the tool pipe, wherein a first air vent of the exhaust device is located between the tunnelling head and the turbulent airflow supply device to collect and receive the toxic and harmful gases, and a second air vent is located above ground to discharge the toxic and harmful gases off-site.
    Type: Application
    Filed: January 4, 2024
    Publication date: June 4, 2026
    Inventors: Jiri ZHOU, Li LUO, Zhihui GAO, Qi CHEN, Yan CHEN, Peilin LI
  • Patent number: 12641652
    Abstract: The present disclosure relates to the field of wireless communication technologies. A terminal device receives configuration information, which indicates that one first combination is mapped to a plurality of downlink reference signals, and one first combination is mapped to a plurality of second combinations. The terminal device then determines a mapping relationship between a first combination and downlink reference signals, a mapping relationship between a first combination and second combinations, and a mapping relationship between second combinations and downlink reference signals based on the configuration information. Next, a first preamble is sent on a first random access channel (RO) included in a selected first combination, and a first uplink reference signal is sent on a first physical uplink shared channel occasion (PO) included in a selected second combination. The selected first combination has a mapping relationship with the selected second combination.
    Type: Grant
    Filed: November 9, 2023
    Date of Patent: May 26, 2026
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Xiuqiang Xu, Yunhao Zhang, Lei Wang, Fan Wei, Yan Chen
  • Patent number: 12634808
    Abstract: A communication method includes receiving indication information that is of a target reference signal and that is sent by a cluster head terminal. The communication method also includes measuring the target reference signal based on the indication information, to obtain a coverage level of a cluster member terminal in a target cell.
    Type: Grant
    Filed: November 25, 2022
    Date of Patent: May 19, 2026
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Yunhao Zhang, Xiuqiang Xu, Yiqun Wu, Yan Chen
  • Publication number: 20260132795
    Abstract: A handheld ice-feel cooling fan is provided, including a fan body and a handheld portion. An air passing passage is disposed within the fan body. An induced draft portion is disposed within the air passing passage. A conduction member is arranged on an outer surface of the handheld portion. A cooling device is disposed within the handheld portion and includes a cooling end and a heat-dissipation air duct. The cooling end is in thermally-conductive connection to the conduction member. After the induced draft portion induces part of an air flow passing through the air passing passage into the heat-dissipation air duct, the air flow is blown outward from a heat-dissipation air out hole. The induced draft portion is arranged in the air passing passage of the fan body. The induced draft portion is disposed on a leeward surface of an air guide blade.
    Type: Application
    Filed: January 10, 2026
    Publication date: May 14, 2026
    Inventor: Yan Chen
  • Publication number: 20260125607
    Abstract: A method for synergistic thermal conversion of straw briquette fuel and carbon dioxide is disclosed. The method includes placing a nickel-based catalyst in the gasifier chamber, maintain the temperature inside the gasifier chamber at 810-960° C., introducing straw briquette fuel into the gasifier chamber, and set the reaction time to 60 minutes. According to different reaction temperatures, no carbon dioxide is introduced from 0 to 10 min, and the amount of carbon dioxide introduced into the gasifier from 5 to 10 min is 0.016-to-0.04-unit weight/min, and the amount of carbon dioxide introduced into the gasifier from 14 to 60 min is 0.012-to-0.03-unit weight/min. After the reaction is completed, the reacted slag is removed or filtered out, the straw briquette fuel is re-added, and timing is started.
    Type: Application
    Filed: October 27, 2022
    Publication date: May 7, 2026
    Inventors: Zhiwei WANG, Tingzhou LEl, Gaofeng CHEN, Youjian ZHU, Qun WANG, Huina ZHU, Tiantian LI, Hui LI, Qiaochong HE, Zhimin DU, Zhengjun WU, Junting ZHAO, Mengge WU, Shuaihua GUO, Yan CHEN
  • Publication number: 20260124190
    Abstract: Disclosed herein are embodiments of a method for treating a disease or condition in a subject, comprising administering to the subject, a pyrazole compound according to formula I. The compound may be administered as a composition, such as a spray-dried formulation. The disease or condition may be hidradenitis suppurativa, or a lymphoid neoplasm, and may be chronic myeloid leukemia or chronic myelomonocytic leukemia.
    Type: Application
    Filed: June 13, 2025
    Publication date: May 7, 2026
    Applicant: Rigel Pharmaceuticals, Inc.
    Inventors: Lu Chou, Matt Duan, Ihab Darwish, Simon Shaw, Somasekhar Bhamidipati, Vanessa Taylor, Yan Chen, Dazhong Fan, Zhushou Luo
  • Patent number: 12621895
    Abstract: The disclosure provides communication methods and apparatuses. One example method includes that after receiving a cell handover command, a terminal device determines discontinuous reception (DRX) configuration information of a target cell. The DRX configuration information of the target cell is consistent with DRX configuration information of a source cell. The terminal device exchanges data at least with the source cell based on the DRX configuration information of the source cell, or with the target cell based on the DRX configuration information of the target cell.
    Type: Grant
    Filed: March 29, 2022
    Date of Patent: May 5, 2026
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Yan Chen, Le Jin, Bingguang Peng, Xi Zhang
  • Publication number: 20260109774
    Abstract: Provided herein are chimeric receptors, such as chimeric antigen receptors (CARs), comprising BCMA-binding molecules, such as anti-BCMA antibodies and antigen-binding fragments thereof, such as heavy chain variable (VH) regions and single-chain antibody fragments, and encoding polynucleotides. In some embodiments, the anti-BCMA chimeric receptors specifically bind to BCMA. Among the anti-BCMA-binding molecules are human antibodies, including those that compete for binding to BCMA with reference antibodies, such as a non-human reference antibody. Also provided are genetically engineered cells expressing the CARs and uses thereof such as in adoptive cell therapy.
    Type: Application
    Filed: August 26, 2025
    Publication date: April 23, 2026
    Applicants: Juno Therapeutics, Inc., Memorial Sloan Kettering Cancer Center
    Inventors: Blythe D. SATHER, Eric L. SMITH, Rupesh AMIN, Aye CHEN, Kimberly HARRINGTON, Collin HAUSKINS, Erik HESS, Cyr DE IMUS, Jon JONES, Audrey OLSHEFSKY, Stefan PONKO, Ruth SALMON, Semih TAREEN, Rebecca WU, Yan CHEN, Steven M. SHAMAH, Csaba PAZMANY, Jui DUTTA-SIMMONS, Mariana Cota STIRNER, Melissa WORKS
  • Publication number: 20260102224
    Abstract: Materials, methods, and systems for additive manufacturing are provided. In some embodiments, a method includes: forming a mixture including a first thermoplastic polymer powder separated from a first additively manufactured dental appliance manufactured during a first powder bed fusion process, where the first thermoplastic polymer powder has a characteristic particle size distribution and a characteristic melt volume rate; in a second powder bed fusion process, depositing a powder layer of the mixture, where the powder layer has a powder packing consistency dependent on the characteristic particle size distribution of the first thermoplastic polymer powder; and in the second powder bed fusion process, applying energy to the powder layer to melt the powder layer to form a part layer of a second additively manufactured dental appliance, where the part layer has a material consistency dependent on the characteristic melt volume rate of the first thermoplastic polymer powder.
    Type: Application
    Filed: October 10, 2025
    Publication date: April 16, 2026
    Inventors: Congqi Yan, Paramjot Singh, Chunhua Li, Yan Chen
  • Publication number: 20260105380
    Abstract: A method for updating a parameter of a large language model is provided. The method may include: generating target text using the large language model based on a text generation request; determining facts to be relied on in the generation process of the target text according to the text generation request to obtain a target fact set; determining reward data according to the target fact set and an information set including unverified information in the target text; and updating the parameter of the large language model based on the reward data.
    Type: Application
    Filed: December 16, 2025
    Publication date: April 16, 2026
    Inventors: Yucheng Wang, Zefeng Cai, Junliang Li, Yan Chen, Yu Ran, Ruiqing Zhang, Jing Liu
  • Publication number: 20260107818
    Abstract: A copper interconnect structure for an integrated circuit chip is provided for forming a good electrical solder connection with a large-sized metal wire easily. The copper interconnect structure includes a copper surface, a metal barrier layer, and a weldable metal layer. The weldable metal layer is formed with a thickness ranging from 0.03 micrometers to 0.05 micrometers over the metal barrier layer.
    Type: Application
    Filed: September 25, 2025
    Publication date: April 16, 2026
    Inventors: Jiyan Peng, Zeqiang Yao, Heng Li, Bin Li, Yan Chen
  • Publication number: 20260097076
    Abstract: Genetically engineered immune cells (e.g., T cells or NK cells) expressing anti-BCMA, anti-TACI, or anti-BCMA/anti-TACI chimeric antigen receptors and uses thereof in cancer therapy. In some embodiments, the genetically engineered immune cells may be armored CAR-T or CAR-NK cells, which further express an armor polypeptide for enhancing CAR-T or CAR-NK cell features.
    Type: Application
    Filed: September 20, 2023
    Publication date: April 9, 2026
    Inventors: Yan CHEN, Garima AGRAHARI, Kehao ZHAO, Jenna NGUYEN, Keming ZHANG, Ning JIANG, Katie O'CALLAGHAN
  • Patent number: 12598026
    Abstract: A sensing method includes determining, by a first communication apparatus, first information. The first information indicates a pulse repetition interval (PRI). The sensing method also includes sending, by the first communication apparatus, the first information to a second communication apparatus. The first information is used by the second communication apparatus to send a reference signal, and a periodicity of the reference signal in time domain is less than or equal to the PRI. The sensing method further includes receiving, by the first communication apparatus, the reference signal from the second communication apparatus. The sending method additionally includes sensing, by the first communication apparatus, a to-be-sensed target based on the reference signal.
    Type: Grant
    Filed: September 22, 2023
    Date of Patent: April 7, 2026
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Xiaohui Peng, Jiajin Luo, Rui Du, Baojian Zhou, Min Yan, Yan Chen, Yinghao Guo
  • Patent number: 12594735
    Abstract: A rotary tablet press comprises a machine frame comprising a press housing and a compression assembly in the press housing including pressure roll assemblies. A connection base extends outwardly from the press housing. A detachable turret module is removably mountable to the base assembly comprising a module base supporting a turret housing. A turret assembly is rotatably mounted in the turret housing about a vertical axis. The turret assembly comprises a plurality of die stations. The turret module is selectively positioned at the base assembly so that the pressure roll assemblies engage the turret assembly to compress a granulation into a tablet at the die stations. A cart is operatively secured to the module base and comprises a controllable lifting mechanism for raising and lowering the turret module to selectively position the module base on the connection base.
    Type: Grant
    Filed: December 20, 2023
    Date of Patent: April 7, 2026
    Assignee: Industrial Pharmaceutical Resources, Inc.
    Inventors: Joseph I. Dougherty, Jr., Yan Chen
  • Patent number: 12594147
    Abstract: Provided herein are curable compositions for use in a high temperature lithography-based photopolymerization process, a method of producing crosslinked polymers using said curable compositions, crosslinked polymers thus produced, and orthodontic appliances comprising the crosslinked polymers.
    Type: Grant
    Filed: June 6, 2024
    Date of Patent: April 7, 2026
    Assignee: Align Technology, Inc.
    Inventors: Robert Liska, Christian Gorsche, Gyorgy Harakaly, Markus Kury, Jurgen Stampfl, Peter Dorfinger, Yan Chen, Chunhua Li, Srinivas Kaza
  • Patent number: 12590353
    Abstract: The present disclosure relates to the field of non-ferrous metal and chemical industries for the production of metal sodium, and discloses a process for the preparation of high purity metallic sodium and the safe treatment of high calcium content sodium slag, the process comprises the following steps: (1) subjecting a liquid sodium obtained from electrolysis to a supergravity separation to obtain a high purity metallic sodium and a high calcium content sodium slag; (2) subjecting said high calcium content sodium slag to at least one roasting process to obtain a roasting slag; (3) leaching said roasting slag with an alkaline liquor to produce sodium hydroxide solution and calcium hydroxide. The process provided by the present disclosure not only greatly reduces the amount of generated sodium slag, but also implements the safe recovery of calcium and sodium resources from the sodium slag.
    Type: Grant
    Filed: November 28, 2022
    Date of Patent: March 31, 2026
    Assignees: BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY, INNER MONGOLIA RUIXIN CHEMICAL CO., LTD
    Inventors: Junqing Pan, Qiuchen Wang, Keyu Wang, Yan Chen, Yanzhi Sun
  • Publication number: 20260084719
    Abstract: A safety-guaranteed control system for automated vehicles (AVs) considers both vehicle and tire stabilities on varying road conditions. Conventional AV control systems may not be sufficient to adequately handle control-dependent and time-varying safety constraints. The system integrates control-dependent barrier functions (CDBF) and time-varying CBFs (TCBFs) with control Lyapunov functions (CLFs) in a quadratic programming problem.
    Type: Application
    Filed: December 2, 2025
    Publication date: March 26, 2026
    Applicant: Arizona Board of Regents on Behalf of Arizona State University
    Inventors: Yan Chen, Yiwen Huang
  • Patent number: 12584209
    Abstract: A fluorocarbon/palladium/magnesium-scandium hydrogen-chromic film and a preparation method thereof are provided. The film includes a magnesium-scandium composite film layer, a palladium catalytic layer, and a fluorocarbon film layer that are sequentially arranged on a substrate. The preparation method includes: growing the magnesium-scandium composite film layer on the substrate first, then growing the palladium catalytic layer in situ on the magnesium-scandium layer, and finally depositing the fluorocarbon film layer on Pd. According to the present invention, the catalytic effect of palladium is utilized to promote reversible conversion between hydrogen and hydrogen atoms during hydrogen absorption and dehydrogenation stages, and a composite scandium element is added to accelerate diffusion of the hydrogen atoms in a magnesium matrix and accelerate formation and decomposition of a hydride, such that the film can be repeatedly and rapidly switched between a reflective state and a transparent state.
    Type: Grant
    Filed: April 27, 2022
    Date of Patent: March 24, 2026
    Assignee: SHANGHAI JIAO TONG UNIVERSITY
    Inventors: Juan Chen, Haolan Fang, Liming Peng, Junjia Liu, Wei Shen, Tingyan Wang, Yan Chen, Wenjiang Ding