Abstract: A semiconductor device including an integrated circuit, a protection layer, and a conductive via is provided. The integrated circuit includes at least one conductive pad. The protection layer covers the integrated circuit. The protection layer includes a contact opening, and the conductive pad is exposed by the contact opening of the protection layer. The conductive via is embedded in the contact opening of the protection layer, and the conductive via is electrically connected to the conductive pad through the contact opening. A method of fabricating the above-mentioned semiconductor device and an integrated fan-out package including the above-mentioned semiconductor device are also provided.

Abstract: Techniques for accelerated authentication include receiving first data that indicates a first portion of user credentials for a first user but not a second portion. It is verified whether the first portion of user credentials is valid. If the first portion of user credentials is valid, then second data that indicates a valid value for the second portion of user credentials for the first user is sent. Other techniques include receiving first data that indicates a first portion of user credentials for a first user but not a second portion of user credentials for the first user. A first message that indicates the first portion of user credentials is sent to a remote process that initiates authentication of the first user based on the first portion of user credentials before receiving second data that indicates the second portion of user credentials for the first user.

Abstract: This invention relates to methods for the synthesis of spiro[2.5]octane-5, 7-dione and spiro[3.5]nonane-6, 8-dione which are useful as intermediates in the manufacture of pharmaceutically active ingredients.

Abstract: Techniques for accelerated authentication include receiving first data that indicates a first portion of user credentials for a first user but not a second portion. It is verified whether the first portion of user credentials is valid. If the first portion of user credentials is valid, then second data that indicates a valid value for the second portion of user credentials for the first user is sent. Other techniques include receiving first data that indicates a first portion of user credentials for a first user but not a second portion of user credentials for the first user. A first message that indicates the first portion of user credentials is sent to a remote process that initiates authentication of the first user based on the first portion of user credentials before receiving second data that indicates the second portion of user credentials for the first user.

Abstract: The present invention relates to the field of pharmaceutical chemistry and pharmacotherapeutics, and in particular to compounds of general formula I, racemates, R-isomers, S-isomers, and pharmaceutically acceptable salts thereof and their mixtures, and the preparation methods thereof and a pharmaceutical composition containing the compounds and uses thereof as an acetylcholine esterase inhibitor.

Abstract: An approach is provided for coordinating service information (e.g., account registration identifiers) across multiple server nodes. A server receives a request to register an identifier for an account. The server determines whether it is a home site for the identifier and processes the request based, at least in part, on the determination.

Abstract: A social communication system and a method thereof are provided. The system includes a server apparatus and a user device. The user device transmits an authorization request to the server apparatus, and the server apparatus inquires an authorized individual whether to agree a user to access a friendship list of the authorized individual. When the authorized individual agrees the user to access the friendship list of the authorized individual, the friendship list of the authorized individual is added to a FOF database. The user device transmits an anonymous social communication service request to the server apparatus to obtain an anonymous social communication service for the user and the authorized individual. Besides, when the service is stopped, the server apparatus inquires both of the authorized individual and the user whether they agree to provide their profiles to each other as the basis for the friendship.

Abstract: A method, apparatus, system, and article of manufacture provide object descriptors for objects in point cloud data for an urban environment by segmenting the point cloud data. Point cloud data for an urban environment is obtained using a ground-based laser scanner. Terrain points are filtered out from the point cloud data using ground filtering. The point cloud data is then segmented into two or more blocks. Objects that lie on neighboring adjacent blocks are combined. Object descriptors for the combined objects are then provided (e.g., to the user or a program used by the user).

Abstract: A method of determining whether a subject has cancer or has a risk of getting cancer comprises: detecting the concentration of Hsp90a in a blood sample of the subject; and if the concentration reaches or exceeds a preset threshold value, determining that the subject has cancer or has a risk of getting cancer, where the threshold value is selected from a range from 50 ng/ml to 120 ng/ml; for example, the threshold value may be 50, 53, 56, 62, 63, 64, 67, 72, 82, 85 or 117 ng/ml, and a numerical value within the ±15% range of the threshold value is regarded having equivalent significance for determination.

Abstract: An air-cooling micro drop pill capsule production line comprises a drop pill system, an air-cooling circulation system and a control system. The drop pill system comprises a molten material tank and a dripper. A vibration apparatus is arranged between the molten material tank and the dripper, and drives the dripper to vibrate up and down. A vibration shear force cuts liquor flowing out from the dripper into drops, and drop pills are formed after the drops fall into the air-cooling circulation system and are cooled. An online monitoring apparatus is arranged on the dripper, and comprises a pulse signal emission mechanism with an emission frequency which is the same as a vibration frequency of the vibration apparatus. The control system controls and regulates a dropping parameter according to a monitoring result of the online monitoring apparatus.

Abstract: The present invention relates to a new use of a known medicament. Specifically, the invention relates to methods and compositions for enhancing the therapeutic efficacy of a therapeutic agent by increasing the uptake of the therapeutic agent by target cells, and in particular relates to a pharmaceutical composition comprising a regulating agent of lipid raft/caveolae-dependent endocytic pathway and some therapeutic agents, such as anti-tumor agents. The invention also relates to a method for screening a regulating agent of lipid raft/caveolae-dependent endocytic pathway capable of enhancing the therapeutic efficacy of anti-tumor agents.

Abstract: An approach is provided for authorizing one or more services from service providers in a communications network. The approach includes receiving a request from a first service provider, the request having an associated primary token and a secondary token identifier, the secondary token identifier relating to resources of a second service provider. Based, at least in part, on the secondary token identifier, a secondary token is identified; and then the secondary token is sent to the first service provider, wherein the first service provider and the second service provider belong to different trust domains and the first service provider can use the secondary token to access resources of the second service provider.

Abstract: A system includes receiving a vehicle characteristic, a rear seatbelt characteristic, and an occupant characteristic and simulating a frontal impact based on the received characteristics. The method further includes determining, via a computing device, an optimal location of at least one component of a rear seatbelt based at least in part on the simulated frontal impact and whether at least one criterion is satisfied.

Abstract: A method, apparatus, system, and computer program product provide the ability to model a polyline boundary from point cloud data. Point cloud data is obtained and boundary cells are extracted. Potential boundary points are filtered from the boundary cells. Line segments are extracted from the potential boundary points and refined. A regularized polygon is obtained by intersecting the refined line segments.

Abstract: The present invention relates to the field of pharmaceutical chemistry and pharmacotherapeutics, and in particular to compounds of general formula I, racemates, R-isomers, S-isomers, and pharmaceutically acceptable salts thereof and their mixtures, and the preparation methods thereof and a pharmaceutical composition containing the compounds and uses thereof as an acetylcholine esterase inhibitor.

Abstract: The invention provides the uses of fibrinogen-420 or alpha EC domain thereof, for inhibiting protein aggregation, refolding the denatured proteins, manufacturing drugs for prevention and/or treatment of protein misfolding diseases, resisting protein denaturation, and detecting the quality of protein products. The invention also provides the drugs for prevention and/or treatment of protein misfolding diseases or protein denatured disease, and the protein stabilizer. The active ingredient of the said drugs and stabilizer is fibrinogen-420 or alpha EC domain thereof.

Abstract: The present invention relates to the diagnosis and treatment of cancer, and specifically to a method of diagnosing the presence, status or metastasis of cancer by detecting plasma Hsp90? having the amino acid sequence of SEQ ID NO:1 as a tumor marker. In addition, the present invention also relates to a method for the treatment of cancer and metastasis.

Abstract: The present invention provides a recombinant fusion protein which stimulates the rejuvenation and reactivation of skin and epidermal cells for improving skin appearance, smoothing wrinkles and freckles, and whitening skin. Particularly, the present invention provides various types of products for improving skin, which contain recombinant fusion protein of human serum albumin (HSA) with cytokine peptides (EGF, FGF, KGF, HGH, HGF, PDGF, GCSF, interferon, IL-11 or IGF) by genetic engineering technology. The fusion protein can be used independently or in a combination or combination with yeast fermentation products, or with varied emulsifiers, thickeners, moisturizer, preservatives, yeasts and ferments.

Abstract: An approach is provided for authorizing one or more services from service providers in a communications network. The approach includes receiving a request from a first service provider, the request having an associated primary token and a secondary token identifier, the secondary token identifier relating to resources of a second service provider. Based, at least in part, on the secondary token identifier, a secondary token is identified; and then the secondary token is sent to the first service provider, wherein the first service provider and the second service provider belong to different trust domains and the first service provider can use the secondary token to access resources of the second service provider.

Abstract: A work piece includes a copper bump having a top surface and sidewalls. A protection layer is formed on the sidewalls, and not on the top surface, of the copper bump. The protection layer includes a compound of copper and a polymer, and is a dielectric layer.