Abstract: Provided is a CD8? binding polypeptide. The CD8? binding polypeptide contains at least one variable domain, and compared with an amino acid sequence as represented by SEQ ID NO:1, the amino acid sequence of the variable domain has substitutions, deletions or additions of one or several amino acids. Further provided are a composition containing the CD8? binding polypeptide and the use thereof in the diagnosis and/or treatment of various diseases including, for example, tumors.

Abstract: Provided is a pharmaceutical composition for enhancing the anti-tumor effect of an EZH2 inhibitor. The pharmaceutical composition includes an EZH2 inhibitor and an SCD1 inhibitor. The SCD1 inhibitor enhances the effect of the EZH2 inhibitor on a solid tumor. Further provided are a related preparation of the pharmaceutical composition and the use thereof in the preparation of an anti-tumor drug.

Abstract: Provided are techniques for building and using a sparse Time Series Database (TSDB). Time series records are received from a native TSDB, where each of the time series records includes a timestamp and one or more tags. Timeslots are determined for shards for the sparse TSDB based on the timestamp included in each of the time series records. The sparse TSDB is built by creating the shards for the determined timeslots and storing the time series records in the shards, while filling in empty ranges in the shards. A query that specifies at least one of the one or more tags is received. It is determined whether to execute the query against the sparse TSDB, and, in response to a determination to execute the query against the sparse TSDB, the query is executed against the sparse TSDB to generate results that are returned.

Abstract: Embodiments of the present disclosure describe an approach for database query processing with database clients. According to the approach, a first set of queries are obtained from a plurality of clients in communication with a database server. A second set of queries are generated by normalizing the first set of queries. A set of access paths corresponding to the second set of queries are determined for retrieving data from at least one of the plurality of clients and the database server. Data is retrieved from at least one of the plurality of clients and the database server based on the set of access paths.

Abstract: A communication method and a communication apparatus. The method includes: the communication apparatus receives first information, where the first information indicates a training policy of a first intelligent model. The communication apparatus performs model training on the first intelligent model according to the training policy. In this way, an intelligent model that meets a communication performance requirement can be obtained while air interface resource overheads are reduced.

Abstract: A pixel structure, a driving method thereof, a display panel, and a display apparatus are provided. The pixel structure includes: a plurality of pixel rows and a plurality of pixel columns. Each pixel row includes: sub-pixels of four different colors. The plurality of pixel columns include: a plurality of first pixel columns and a plurality of second pixel columns arranged alternately. Each of the first pixel columns includes: sub-pixels of three of the four different colors. Each of the second pixel columns includes: sub-pixels of another color other than the three of the four different colors.

Abstract: This application provides a calibration method and apparatus. The method includes: determining first channel state information and second channel state information, where the first channel state information is obtained through prediction via a first channel prediction model, and the second channel state information is determined based on channel estimation on a downlink signal from an access network device; and sending first information to the access network device if a difference metric value between the first channel state information and the second channel state information is greater than or equal to a first threshold, where the first information indicates the second channel state information.

Abstract: This application provides a data processing method and a communication apparatus. The method includes: receiving or sending a plurality of reference signals; obtaining a first channel data set, where the first channel data set is a set of a plurality of pieces of channel data obtained based on the plurality of reference signals; obtaining a data quality screening policy, where the data quality screening policy is used to obtain, through screening, model training data that meets a data quality requirement; and screening the channel data in the first channel data set according to the data quality screening policy, to obtain a training data set. In this way, quality of the training data for model training is improved, so that a trained intelligent model meets a performance requirement.

Abstract: This application provides a communication method and apparatus. The method includes: determining a first downlink signal and a second downlink signal, where the first downlink signal is a downlink signal determined based on an output of a first prediction model, an input of the first prediction model is determined based on Y pieces of downlink measurement information in X pieces of downlink measurement information, and the second downlink signal is determined based on the X pieces of downlink measurement information; and indicating the second downlink signal and the Y pieces of downlink measurement information to an access network device if the first downlink signal and the second downlink signal meet a first condition. According to the method, the first prediction model can be updated based on the foregoing information, and performance of the prediction model can be continuously improved.

Abstract: A communication method and an apparatus. A terminal device (or an access network device) obtains a channel feature through inference by using a channel feature extraction model, where the channel feature corresponds to a channel between the terminal device and the access network device. The terminal device (or the access network device) sends the channel feature to a location management function LMF. The LMF obtains, based on the channel feature, positioning information of the terminal device through inference by using a positioning information obtaining model. The LMF may determine location information of the terminal device based on the positioning information. An artificial intelligence model may be used to implement positioning or assist in implementing positioning of the terminal device.

Abstract: A computer-implemented method, system and computer program product for improving performance of a distributed database. A query is received to store version data in the distributed database. Upon receiving the query to store the version data, the version data is stored in a row of a data page of a main table of a heap organized table/index organized table of the distributed database, where the row of the data page of the main table of the heap organized table/index organized table of the distributed database contains a pointer pointing to a later/previous version of the version data if the later/previous version of the version data is stored in the data page thereby chaining version data bi-directionally.

Abstract: A method includes receiving, by a computing device, a Structured Query Language (SQL) query from a user; generating, by the computing device, execution structures from the SQL query; generating, by the computing device, test results by running the SQL query with the execution structures; building, by the computing device, logs which record information of the running of the SQL query; generating, by the computing device, a candidate execution structure using the information from the logs; normalizing, by the computing device, the SQL query using the candidate execution structure; running, by the computing device, the normalized SQL query in a database; and comparing, by the computing device, results of the normalized SQL query to the test results.

Abstract: A method, computer system, and a computer program product for risk analysis is provided. The present invention may include receiving an access request. The present invention may include analyzing a matrix barcode associated with the access request. The present invention may include validating the matrix barcode. The present invention may include providing a validation status to a user.

Abstract: Methods and compositions for treating or preventing nonalcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH) are provided, including tripartite motif-containing protein 31 (TRIM31) and rhomboid 5 homolog 2 protein (RHBDF2), in particular a method for promoting the degradation of RHBDF2 by E3 ligase TRIM31. The invention also provides methods for treating NAFLD/NASH by reagents promoting TRIM31 expression or inhibit RHBDF2 expression, comprising recombinant lentiviral vector, adeno-associated virual vector, compounds, extracts of traditional Chinese medicine, etc.

Abstract: A computer-implemented method to estimate computing cost of database queries. The method includes receiving a query. The method also includes generating one or more access plans for the query. The method further includes dynamically generating a learning model based on each of the generated access plans. The method includes estimating, by the learning model and for each of the one or more access plans, a predicted cost to execute the query. The method includes selecting, based on the predicted cost, a first access path associated with a lowest cost of the predicted costs and executing the query according the selected access path.

Abstract: An image processing method based on a dither algorithm and a display device are disclosed. The method includes: obtaining a to-be-displayed image, and determining a first region and a second region of the to-be-displayed image, where the first region and the second region are determined according to a coverage range of a visual field of a user on a display screen; determining a first dither algorithm corresponding to the first region and a second dither algorithm corresponding to the second region, where parameter matrices the first dither algorithm and the second dither algorithm are different; and obtaining a rendered image of the to-be-displayed image by rendering the first region according to the first dither algorithm and rendering the second region according to the second dither algorithm, and displaying the rendered image on the display screen.

Abstract: A method, system, and computer program product that are configured to: receive a Structured Query Language (SQL) statement including placeholders; generate sets of predicted values for the placeholders; generate candidate access paths in a database using the sets of predicted values; receive a query including the SQL statement with actual values instead of the placeholders; select one of the candidate access paths based on determining similarities of the actual values to ones of the sets of predicted values; in response to the selected one of the candidate access paths being acceptable, execute the query using the selected one of the candidate access paths; and in response to the selected one of the candidate access paths not being acceptable, generate a new access path in the database using the actual values, and execute the query using the new access path.

Abstract: The present application relates to the technical field of chemical production, and particularly relates to a molten iron catalyst for high-temperature Fischer-Tropsch synthesis, a preparation method of the molten iron catalyst and an application of the molten iron catalyst in preparation of high-carbon ?-olefin from synthesis gas. The molten iron catalyst comprises iron oxides and a cocatalyst, and mass contents of components are: potassium oxide per 0.1-1 g/100gFe; strontium oxide 0.1-1 g/100gFe; manganese oxide 1-20 g/100gFe, and rare earth metal oxides 1-10 g/100gFe; the rest is iron oxides. The molar ratio of ferric iron to double ferrous iron in the iron oxides, namely Fe3+/2Fe2+, is 0.4-1.5. The application aims to provide a molten iron catalyst with high strength, high activity, and high selectivity of higher ?-olefin.

Abstract: A display compensating method, display compensating device, and display device are provided, which relates to field of display and addresses the issues of poor screen uniformity, grayscale relationship change of sub-pixel due to ambient temperature change, and display screen brightness affected by ageing offset of threshold voltage corresponding to the sub-pixel. The display compensating method is applied to the display device, including: converting a received grayscale signal into a brightness signal; performing an optical compensation on a display brightness of the display device based on the brightness signal; converting a corresponding brightness signal on which the optical compensation is performed into a voltage signal; compensating for a threshold voltage corresponding to each sub-pixel in the display device based on the voltage signal; and compensating for operating parameters of the display device for the display device at different operating temperatures.

Abstract: A dataset is determined to include skewed data and based on determining that the dataset includes skewed data, one or more sparse indexes for the skewed data of the dataset are built. A sparse index of the one or more sparse indexes is for a range of data of the skewed data, and the building the sparse index includes indicating one pointer for a selected record of the range of data and indicating another pointer for another selected record of the range of data. The sparse index is provided to be used in a query of the dataset.