Abstract: A groove-free quick-insert pipe clamp includes a pipe clamp group which is combined and fixed with each other and is sleeved between butted pipes, an installation cavity arranged inside the pipe clamp group, and a positioning ring which is movably installed in the installation cavity and realizes shrinkage of an inner diameter by deformation. A bevel group matched with each other is arranged between a side wall of the installation cavity and the positioning ring. When the pipe moves away from the pipe clamp group, the side wall of the installation cavity is driven to move relative to the positioning ring, and the side wall of the installation cavity squeezes the positioning ring toward the axial direction of the pipe through the bevel group. The pipe clamp can tightly press the pipe by the positioning ring through deformation of the shrinkage of the diameter of the positioning ring.

Abstract: The present disclosure relates to use of a probiotic composition in the manufacture of a drug for tumor treatment, the probiotic including Bifidobacterium animalis subsp. lactis. The drug further includes one or more tumor treatment drugs, such as an immune signaling pathway regulator PD-1/PDL-1. The drug is used for tumor immunotherapy.

Abstract: Methods, apparatuses, and systems for collecting and validating web traffic data, including receiving preprocessed log data representing an activity of a device interacting with a data service; validating the preprocessed log data in accordance with a predetermined format, the format comprising a field indicative of a predetermined data type and a field indicative of a predetermined validation condition associated with the predetermined data type; and generating metadata associated with validated preprocessed log data.

Abstract: Coated crossflow filter membranes, crossflow filters comprising the coated filter membranes and crossflow filtration systems for separating material such as biological material sensitive to temperature, dissolved gases, and mechanical damage are disclosed.

Abstract: A collaborative erosion-control method of releasing-splitting-supporting based on coal mass pressure relief and roof pre-splitting provided by the disclosure includes the following steps: step 1, driving into a coal seam to release pressure; step 2, low roof pre-splitting during driving process; step 3, supporting of roadway surrounding rock and support reinforcement; step 4, floor destressing of the roadway; step 5, high roof pre-splitting before mining; step 6, destressing and supporting of the advanced roadway surrounding rock during the mining process of the working face. The collaborative erosion-control method of releasing-splitting-supporting based on coal mass pressure relief and roof pre-splitting, and to carry out local pressure relief, roof pre-splitting and reinforcement support construction in the whole cycle of the coal working face in a progressive manner, so as to achieve the prevention and control of rock burst in the working face.

Abstract: A collaborative erosion-control method of releasing-splitting-supporting based on coal mass pressure relief and roof pre-splitting provided by the disclosure includes the following steps: step 1, driving into a coal seam to release pressure; step 2, low roof pre-splitting during driving process; step 3, supporting of roadway surrounding rock and support reinforcement; step 4, floor destressing of the roadway; step 5, high roof pre-splitting before mining; step 6, distress sing and supporting of the advanced roadway surrounding rock during the mining process of the working face. The collaborative erosion-control method of releasing-splitting-supporting based on coal mass pressure relief and roof pre-splitting, and to carry out local pressure relief, roof pre-splitting and reinforcement support construction in the whole cycle of the coal working face in a progressive manner, so as to achieve the prevention and control of rock burst in the working face.

Abstract: Disclosed is producing recombinant SARS-CoV-2 spike protein in a pre-fusion state, using furin knock out or knockdown mammalian cells (such as HEK293, CHO or other mammalian cells) and using them to generate antibodies and related binding agents. The antibodies/binding agents can be used in SARS-CoV-2 detection assays or in diagnosis of active or prior infection with SARS-CoV-2; in prophylaxis or as a therapeutic; or for prophylactic or therapeutic use against coronaviruses related to SARS-CoV-2.

Abstract: Provided are a composite material and a preparation method therefor. The composite material comprises: a base layer; a first plant fibre fabric located on the upper surface of the base layer; optionally, a second plant fibre fabric located on the lower surface of the base layer; and resins present in each layer. The composite material has a decorative performance and an improved mechanical performance.

Abstract: A three-way clamp includes a first clamp shell and a second clamp shell capable of being connected to or detached from each other. Each of the first clamp shell and the second clamp shell includes three engaging portions. The engaging portion includes an accommodating cavity. The two clamp shells are respectively provided with an engaging claw and an engaging groove. A connector prefabricated component including the clamp includes a connecting pipe fixed in the clamp body, wherein the accommodating cavity is provided with a sealing component for sleeving pipe opening. During construction, a straight pipe to be connected is inserted into the sealing component. Then the clamp body is tightened, and the sealing component tightly presses on a pipe body of the straight pipe to achieve sealing.

Abstract: The disclosure provides a variable dip fault slip simulation test method, which relates to the technical field of indoor simulation test of underground engineering. The variable dip fault slip simulation test method of the disclosure adopts a sample device and a loading device, which includes the following steps: Step 1. sample preparation; Step 2. sample assembly; Step 3. loading preparation; Step 4. sample loading. The variable dip fault slip simulation test method of the disclosure can prepare rock like samples with different dip interfaces, simulate the slip failure process of faults with different dip angles, as well as the normal dip slip and reverse dip slip of faults, facilitate the operation of slip simulation test, and collect test data automatically and accurately.

Abstract: Disclosed is producing recombinant SARS-CoV-2 spike protein in a pre-fusion state, using furin knock out or knockdown mammalian cells (such as HEK293, CHO or other mammalian cells) and using them to generate antibodies and related binding agents. The antibodies/binding agents can be used in SARS-CoV-2 detection assays or in diagnosis of active or prior infection with SARS-CoV-2; in prophylaxis or as a therapeutic; or for prophylactic or therapeutic use against coronaviruses related to SARS-CoV-2.

Abstract: A clamp connector includes a first clamp ring component, wherein the first clamp ring component includes two end portions, where one end portion is provided with two stress structures, and a mounting space; a second clamp ring component, wherein the second clamp ring component includes additional two end portions, one end portion is provided with a fixing structure capable of being mounted in or dismounted from the mounting space, and the fixing structure fits with the two stress structures; and both the one end portion of the first clamp ring component and one end portion of the second clamp ring component are provided with mechanisms for locking. When the one end portion of the first clamp ring component and the one end portion of the second clamp ring component are tightly locked, the two stress structures and the fixing structure are in a squeezed and close fit state.

Abstract: Disclosed is producing recombinant SARS-CoV-2 spike protein in a pre-fusion state, using furin knock out or knockdown mammalian cells (such as HEK293, CHO or other mammalian cells) and using them to generate antibodies and related binding agents. The antibodies/binding agents can be used in SARS-CoV-2 detection assays or in diagnosis of active or prior infection with SARS-CoV-2; in prophylaxis or as a therapeutic; or for prophylactic or therapeutic use against coronaviruses related to SARS-CoV-2.

Abstract: The disclosure provides a variable dip fault slip simulation test method, which relates to the technical field of indoor simulation test of underground engineering. The variable dip fault slip simulation test method of the disclosure adopts a sample device and a loading device, which includes the following steps: Step 1. sample preparation; Step 2. sample assembly; Step 3. loading preparation; Step 4. sample loading. The variable dip fault slip simulation test method of the disclosure can prepare rock like samples with different dip interfaces, simulate the slip failure process of faults with different dip angles, as well as the normal dip slip and reverse dip slip of faults, facilitate the operation of slip simulation test, and collect test data automatically and accurately.

Abstract: The present disclosure provides a method for predicting a responsiveness of a subject to treatment with an immune checkpoint inhibitor therapy such as a PD-1 signaling pathway inhibitor from a sample comprising the gut microbiota of the subject through the presence and abundance information of microorganisms of one or more genera. Also disclosed are sequences and compositions for detecting intestinal microorganisms, and related uses thereof.

Abstract: Disclosed is producing recombinant SARS-CoV-2 spike protein in a pre-fusion state, using furin knock out or knockdown mammalian cells (such as HEK293, CHO or other mammalian cells) and using them to generate antibodies and related binding agents. The antibodies/binding agents can be used in SARS-CoV-2 detection assays or in diagnosis of active or prior infection with SARS-CoV-2; in prophylaxis or as a therapeutic; or for prophylactic or therapeutic use against coronaviruses related to SARS-CoV-2.

Abstract: Disclosed is producing recombinant SARS-CoV-2 spike protein in a pre-fusion state, using furin knock out or knockdown mammalian cells (such as HEK293, CHO or other mammalian cells) and using them to generate antibodies and related binding agents. The antibodies/binding agents can be used in SARS-CoV-2 detection assays or in diagnosis of active or prior infection with SARS-CoV-2; in prophylaxis or as a therapeutic; or for prophylactic or therapeutic use against coronaviruses related to SARS-CoV-2.