Abstract: Compounds comprising therapeutic polypeptide Fc conjugates are provided that have activity at one or more of the GIP, GLP-1 and glucagon receptors. The compounds have structural features resulting in activity and extended duration of action at one or more of these receptors. Methods also are provided for treating diseases and/or conditions such as obesity, chronic weight management, and type 2 diabetes mellitus.

Abstract: A method for determining a self-healing area effect of a metallized film is provided. The method includes: preparing metallized film samples with different areas, conducting breakdown and a self-healing experiment to obtain data groups of breakdown field strengths and corresponding self-healing characteristic parameters with the different areas; determining an expression of the self-healing characteristic parameters with the breakdown field strengths and the areas of the metallized film samples according to the data groups, and simultaneously determining distribution properties of the self-healing characteristic parameters according to distribution properties of the breakdown field strengths; and obtaining a relationship between the self-healing characteristic parameters and the areas of the metallized films according to an area effect of the breakdown field strengths and the distribution properties of the self-healing characteristic parameters.

Abstract: Base station antennas, and components for base station antennas, such as reflectors, feeder components, frames, and column components. A base station antenna may include a reflector; a first radiator located at the front side of the reflector; mutually parallel first and second ground plates extending backward from the reflector and basically perpendicular to the reflector; and a first conductor strip extending between the first and second ground plates and configured to feed power to the first radiator. The first conductor strip and the first and second ground plates may be configured as a first stripline transmission line. The reflector and the first and second ground plates may be configured as one piece so that the reflector is grounded via the first and second ground plates without soldering.

Abstract: A computer includes a processor and a memory, and the memory stores instructions executable by the processor to formulate a plurality of control barrier functions for a host vehicle, each control barrier function based on a respective kinematic state of a respective target vehicle; determine respective CBF input accelerations based on the respective control barrier functions; formulate a control-Lyapunov function for the host vehicle based on a target speed for the host vehicle; determine a Lyapunov input acceleration based on the control-Lyapunov function; select an input acceleration from an acceleration set including the CBF input accelerations and the Lyapunov input acceleration; and actuate a component of the host vehicle according to the selected input acceleration.

Abstract: The present application relates to modified-zeolite immobilized algae beads and a preparation method thereof and use thereof. The modified-zeolite immobilized algae beads are prepared by modifying zeolite with sodium bicarbonate and chitosan, followed by immobilizing the modified zeolite with Chlorella in embedding gel beads to achieve the immobilization of the algae beads.

Abstract: The present disclosure provides memories, operation methods of memories, and memory systems. An example memory includes: a memory cell array, word lines, a first select line, and a peripheral circuit. The peripheral circuit is configured to: in a first period of a recovery period of a verify operation, apply a first voltage to a first word line, and apply a second voltage to a second word line, wherein the second voltage is greater than the first voltage; in a second period of the recovery period of the verify operation, apply a third voltage to the first select line; and in a third period of the recovery period of the verify operation, apply a fourth voltage to the first word line, and apply a fifth voltage to the second word line, wherein the fifth voltage is greater than the fourth voltage.

Abstract: Compounds comprising therapeutic polypeptide Fc conjugates are provided that have activity at one or more of the GIP, GLP-1 and glucagon receptors. The compounds have structural features resulting in activity and extended duration of action at one or more of these receptors. Methods also are provided for treating diseases and/or conditions such as obesity, chronic weight management, and type 2 diabetes mellitus.

Abstract: Provided are a crystal form of a neuroactive steroid derivative and use thereof, belonging to the field of pharmaceutical technology. The crystal form of the neuroactive steroid derivative (having a structure represented by formula I) has characteristic diffraction peaks expressed as 2? angles in an X-ray powder diffraction pattern obtained by using Cu-K? radiation, including 11.450±0.200°, 15.724±0.200°, 19.040±0.200°, 22.955±0.200° and 24.975±0.200°.

Abstract: Systems and methods can be implemented to conduct a visual search as a service in a variety of applications. In various embodiments, a system is configured to provide searching capabilities of content provided by a first entity in response to a search request by a second entity. An image provided by the second entity can be used by the system as a query image to search the content of the first entity. In an embodiment, the first entity can be a commercial entity providing such a system with image related content regarding its products and services such that any number of individual consumers can search for particular products and services of the commercial entity via their communication enabled devices. In addition, such systems can be arranged for other embodiments to provide customized searches of a single source by many individual devices. Additional systems and methods are disclosed.

Abstract: Compounds comprising therapeutic polypeptide Fc conjugates are provided that have activity at one or more of the GIP, GLP-1 and glucagon receptors. The compounds have structural features resulting in activity and extended duration of action at one or more of these receptors. Methods also are provided for treating diseases and/or conditions such as obesity, chronic weight management, and type 2 diabetes mellitus.

Abstract: Provided is a method for generating multimodal content, an electronic device and a storage medium, relating to the field of artificial intelligence technology and specifically to the fields of natural language processing, computer vision, human-computer interaction, deep learning and other technologies, and can be applied to scenarios such as intelligent document generation. The method includes: receiving a user input, the user input comprising material uploaded by a user and a user instruction; analyzing the user input to determine the user's generation intent; outputting at least one content generation option based on the generation intent; and generating multimodal content based at least on the generation intent and the material in response to the user's selection of a target content generation option.

Abstract: An access network device receives configuration information of a first QoS flow, where the first QoS flow supports a plurality of types of data packets, and the configuration information includes QoS parameters respectively corresponding to the plurality of types; and performs, after receiving a first data packet in the first QoS flow, downlink scheduling on the first data packet based on a QoS parameter corresponding to a type of the first data packet.

Abstract: Electrolyte materials having the formulas Li3ScBr6, Li5ScBr8, or Li4ScBr7 are provided, wherein the electrolyte material crystallizes in a space group selected from the group consisting of P-31c, P312, P-31m, P1, C2/m, and R3c. A solid-state battery comprising Li3ScBr6, Li5ScBr8, or Li4ScBr7 electrolyte materials is provided. Methods for making Li3ScBr6, Li5ScBr8, and Li4ScBr7 electrolyte materials are also provided.

Abstract: Electrolyte materials having the formulas Li2CaCl4 or Li3Ca2Cl7 are provided, wherein the electrolyte material crystallizes in a space group selected from the group consisting of Cm, Imma, Cmmm, and P1. A solid-state battery comprising Li2CaCl4 or Li3Ca2Cl7 electrolyte materials is provided. Methods for making Li2CaCl4 and Li3Ca2Cl7 electrolyte materials are also provided.

Abstract: Electrolyte materials having the formulas Li3Ca3Cl7O, Li5Ca2Cl7O, and Li5CaCl5O are provided, wherein the electrolyte material crystallizes in a space group selected from the group consisting of Cm, P2_1, Pc, Pm, P3m1, P1, and Pmn2_1. A solid-state battery comprising Li3Ca3Cl7O, Li5Ca2Cl7O, or Li5CaCl5O electrolyte materials is provided. Methods for making Li3Ca3Cl7O, Li5Ca2Cl7O, and Li5CaCl5O electrolyte material are also provided.

Abstract: Provided in the present application are an image encoding method and apparatus, an image decoding method and apparatus and a storage medium. The encoding method comprises: acquiring an encoding unit, wherein the encoding unit is an image block in an image to be processed, and comprises encoding blocks of a plurality channels, the plurality channels comprise a first channel, and the first channel is any one of the plurality channels; and encoding the encoding block of the first channel according to a first encoding mode. The method is suitable for image encoding and decoding processes, and is used for solving the problem of substream buffers being set to be excessively large.

Abstract: Electrolyte materials having the formulas Li3ScI6 or Li5ScI8 are provided, wherein the electrolyte material crystallizes in a space group selected from the group consisting of R3m, Cmmm, and C2/m. A solid-state battery comprising Li3ScI6 or Li5ScI8 electrolyte materials is provided. Methods for making Li3ScI6 or Li5ScI8 electrolyte material are also provided.

Abstract: A lithium garnet material has the formula Li7-wLa3-x(Ax1Bx2Cx3)Zr2-y(Cy1Dy2Ey3)O12, where ?0.2?w?0.2, A is one or a combination of Na+ and K+, B is one or a combination of two or more of Mg2+, Ca2+, Sr2+, and Ba2+, and C is one or a combination of two or more of Y3+, Sc3+, and Ce3+ on the La3+ site, and D is one or a combination of two or more of Si4+, Sn4+, Ti4+, and Ce4+ and E is one or a combination of two or more of Sb5+, Bi5+, Ta5+, and Nb5+ on the Zr4+ site, 0<x<2, 0<y<2, and x1+x2+x3=x and y1+y2+y3=y either satisfy a charge balance mechanism with their respective doping site or satisfy any combination that maintains the charge neutrality of the material.

Abstract: The invention relates to method for the efficient expression and purification and application of a recombinant fusion protein of MANNase and homologues thereof and GLP-1. Through genetic recombination technology, soluble proteins are obtained by using high density fermentation of Pichia pastoris to induce secretory expression, followed by isolation and purification by filtration and concentration to obtain high yield of target proteins. The high fermentation expression and simple isolation steps solve the limitations of the current GLP-1 analogs such as low drug yield, high cost and the need for frequent injections. More importantly, the fusion protein has hypoglycemic effect not only by injection, but also by oral administration for hypoglycemia and weight reduction, which has good application value in obese and pre-diabetic patients. It also provides a basis for further research on the mechanism of hypoglycemia and weight loss of mannanase and homologues thereof with GLP-1 recombinant fusion protein.

Abstract: Methods and systems for generating a global database profile are described. The methods and systems receive, from each of a plurality of layers of a database system, profiling data, the profiling data comprising a first set of profiling data received from a first layer of the plurality of layers and a second set of profiling data received from a second layer of the plurality of layers, the profiling data representing database logic operations and physical states at each of the plurality of layers. The methods and systems aggregate the profiling data received from the plurality of layers into global database profiling data associated with the plurality of layers of the database system and present visual output based on the profiling data, the visual output representing the database logic operations and the physical states at each of the plurality of layers over time.