Abstract: There are provided measures for enabling/realizing more efficient radio link problem handling in a mobile communication system. Such measures exemplarily comprise detecting a radio problem of a radio link carrying a network connection of a communication device, and initiating a recovery procedure for recovering the connection on said radio link and a re-establishment procedure for re-establishing the connection on an alternative radio link, upon detection of the radio link problem, before a radio link failure of said radio link is declared.

Abstract: Provided is a method for preparing a PD-1 gene-modified humanized animal model. The method utilizes the CRIPSR/Cas9 technique to replace partial fragments of a mouse PD-1 gene with fragments of a human PD-1 gene using homologous recombination by constructing a targeting vector, thereby preparing a gene-modified humanized mouse. This mouse can normally express a PD-1 protein containing the functional domain of the human PD-1 protein, and can be used as an animal model for mechanism research regarding PD-1, PD-L1 and other signals, for screening regulators, and for toxicological research. The method has an important and high application value in studies on functions of the PD-1 gene and in the development of new drugs.

Abstract: A hard macro includes a periphery defining a hard macro area and having a top and a bottom and a hard macro thickness from the top to the bottom, the hard macro including a plurality of vias extending through the hard macro thickness from the top to the bottom. Also an integrated circuit having a top layer, a bottom layer and at least one middle layer, the top layer including a top layer conductive trace, the middle layer including a hard macro and the bottom layer including a bottom layer conductive trace, wherein the top layer conductive trace is connected to the bottom layer conductive trace by a via extending through the hard macro.

Abstract: The present invention discloses a method for remolding bone marrow microenvironment in a subject having an impaired bone marrow microenvironment, which comprises implanting a composition comprising isolated mesenchymal stromal cells (MSCs) into the bone marrow cavity of the subject. The method of the present invention successfully remolds the bone marrow microenvironment, recovers the normal hematopoiesis of bone marrow, inhibits/delays the pathological process of leukemia and significantly prolongs the survival period. In addition, the method according to the present invention can be used for the treatment of hematologic tumors such as leukemia and aplastic anemia (AA), which is safe and effective but has no side effects.

Abstract: A data transmission method and a network device are provided. The method can include: determining, by a first network device, that a terminal device enters an RRC inactive state; sending, by the first network device, a first message to a second network device, where the first message is used to configure the second network device, so that the second network device transmits data for the terminal device in the RRC inactive state; and receiving, by the first network device, an acknowledgment message the first message and sent by the second network device. The second network device can transmit data of the terminal device to the first network device to enable the first network device to send the data to a core network, without having to establish a path between the second network device and the core network for the second network device to send the data to the core network.

Abstract: Provided is a method for preparing a PD-1 gene-modified humanized animal model. The method utilizes the CRIPSR/Cas9 technique to replace partial fragments of a mouse PD-1 gene with fragments of a human PD-1 gene using homologous recombination by constructing a targeting vector, thereby preparing a gene-modified humanized mouse. This mouse can normally express a PD-1 protein containing the functional domain of the human PD-1 protein, and can be used as an animal model for mechanism research regarding PD-1, PD-L1 and other signals, for screening regulators, and for toxicological research. The method has an important and high application value in studies on functions of the PD-1 gene and in the development of new drugs.

Abstract: The present invention provides a multi-connectivity establishment method, communication system, user equipment (UE) and access point (AP), the method comprising: a UE setting up a first RRC connection with a CN node via a first AP; the UE, when the first AP transmits to the UE a notification that RAN anchoring function is supported by the first AP and the UE determines to use a second AP to set up a second RRC connection, transmitting a second connection request message to the second AP, wherein, the second connection request message including identifying information of the first AP; and the second AP, according to the second connection request message, transmitting an anchoring request message to the first AP so as to obtain UE context information, and setting up the second RRC connection with the UE according to the UE context information.

Abstract: This application provides a display panel and a display device. The display panel includes an array substrate, an encapsulation layer and a fingerprint recognition module. The array substrate includes a first substrate and a plurality of light-emitting units on the first substrate. The encapsulation layer is disposed on top of the plurality of light-emitting units. The fingerprint recognition module is disposed on the encapsulation layer and includes at least one fingerprint recognition unit. The projection of the fingerprint recognition unit onto the array substrate is located in the non-light-emitting area of the first substrate. The non-light-emitting area is located between two adjacent light-emitting units.

Abstract: The present invention provides a connection setup method, the corresponding user equipment, common central control node and communication system. A connection setup method performed by a user device, comprising: acquiring information transmitted by a plurality of cells; determining a plurality of candidate cells according to the information transmitted by the plurality of cells, sending a common connection setup request for the plurality of candidate cells to a common central control node, the common central control node corresponding to each of the plurality of candidate cells; receiving a common connection setup message for a plurality of connecting cells transmitted by the common central control node, the plurality of connecting cells being determined from the plurality of candidate cells by the common central control node, so that the user equipment establishes multiple radio connections through each of the plurality of connecting cells.

Abstract: Provided are a method and a device for detecting a genetic mutation, and a kit for typing genotypes of a pregnant woman and a fetus. The method comprises: performing high-throughput sequencing on free DNA in a pregnant woman's peripheral blood to obtain sequencing data; comparing the sequencing data with reference genome to obtain SNP sites; performing mixed genotyping on each SNP site to obtain target genotypes for each SNP site; and selecting a mutation site that causes the gene mutation from the genotype of the fetus in the target genotypes.

Abstract: An aqueous solvent composition is provided, comprising a nucleophilic component having one or more sterically unhindered primary or secondary amine moieties, a Brønsted base component having one or more basic nitrogen moieties, a water-soluble organic solvent, and water. A biphasic composition is provided, comprising one or more carbamate compounds, one or more conjugate acids of Brønsted base, a water-soluble organic solvent, and water. A biphasic CO2 absorption process is also provided, utilizing the biphasic solvent composition.

Abstract: Techniques perform data input and output. For example, there is provided a technique for updating a data pattern table. The technique involves: during a time period for establishing or updating the data pattern table: receiving a data write request; making statistics of a frequency of data being written; and writing data frequently used and an identification of the data to a corresponding entry of the data pattern table based on a result of the statistics. Using such a technique, a data pattern table can be customized and data storage efficiency can be improved.

Abstract: Systems and methods for modeling subsurface rock formations based on well log data are provided. Systems include a downhole tool for acquiring data from which borehole dips may be picked and a processor including machine-readable instructions for curvature analysis based on inputs generated from the picked borehole dips data and which may be independent of 2D cross section model orientation. Methods (which may be incorporated in the machine-readable instructions corresponding to the systems) include pre-processing borehole dips data to generate inputs such as true stratigraphic thickness index, Local Constant Dips, borehole structural dip, and attributes for structural dip projections which may be used in a curvature analysis process for generating curvature logs such as standard, curvature along axis and curvature normal to axis logs from for smoothed dips, short zone structural dips and/or long zone structural dips.

Abstract: The present invention relates to a method for promoting acetylglucosamine synthesis of Bacillus subtilis, which belongs to the field of genetic engineering. The present invention adopts the recombinant Bacillus subtilis BSGNKAP2 as a starting strain, exogenously introducing pyruvate carboxylase BalpycA derived from Bacillus cereus, eliminating the central carbon metabolism overflow of the Bacillus subtilis and avoiding the synthesis of the by-product acetoin; further, five exogenous reducing force metabolic reactions are introduced to replace the reaction of generating NADH in glycolysis pathway and tricarboxylic acid cycle to reconstruct intracellular reducing force metabolism, which specifically comprise glyceraldehyde-3-phosphate ferredoxin dehydrogenase, isocitrate NAD+ dehydrogenase, a malate quinone dehydrogenase, a ketoacid ferredoxin oxidoreductase and a nitrogenase ferritin. In a shake-flask fermentation process using a complex medium, acetylglucosamine yield of the recombinant strain BSGNKAP8 is 24.

Abstract: Provided are a display panel and a display device. The display panel includes a display assembly, the display assembly includes an array substrate and a plurality of pixel units disposed on the array substrate; and a fingerprint recognition assembly, the fingerprint recognition assembly disposed on one side of the array substrate facing away from the plurality of pixel units, the fingerprint recognition assembly includes a first substrate and at least one fingerprint recognition unit disposed on the first substrate, the fingerprint recognition unit includes a photosensitive region. The array substrate includes a plurality of transparent regions and a plurality of non-transparent regions. Along a direction perpendicular to the array substrate, at least a portion of the plurality of transparent regions in the array substrate is covered by a photosensitive region of any one of the at least one fingerprint recognition units.

Abstract: Provided are a display panel and a display device. The display panel includes a display assembly and a fingerprint recognition assembly. The display assembly includes a base substrate, a plurality of pixel driving circuit units disposed on one side of the base substrate and at least two kinds of metal wires extending along a first direction, the plurality of pixel driving circuit units are arranged in a matrix along the first direction and a second direction, and a first gap region is formed between adjacent two of the plurality of pixel driving circuit units in the first direction. The display panel provided by the present disclosure provides the at least two kinds of metal wires to include a plurality of first type metal wires and a plurality of second type metal wires.

Abstract: An example technique is provided that includes establishing a multi-cell communication session for a user device, the multi-cell communication session including a plurality of wireless connections that include a wireless connection between the user device and each of a plurality of cells in a same frequency layer, wherein the plurality of cells are used to transmit data to or receive data from the user device using a coordinated multi-cell communication technique, and performing, by the user device, communication session failure detection for the multi-cell communication session taking into account signal gains provided by the coordinated multi-cell communication technique.

Abstract: Provided are a display panel and a display device. The display panel includes a display assembly, the display assembly includes an array substrate and a plurality of pixel units disposed on the array substrate; a fingerprint recognition assembly disposed on one side of the array substrate facing away from the plurality of pixel units, the fingerprint recognition assembly includes a first substrate and at least one fingerprint recognition unit disposed on the first substrate; and the array substrate includes a plurality of transparent regions and a plurality of non-transparent regions, the array substrate further includes a plurality of metal wires, a ratio of a line width of a portion of at least one of the metal wires disposed in at least one respective transparent region to a line width of a portion of the at least of the metal wires disposed in a respective non-transparent region is less than 1.

Abstract: Isolated polynucleotides and polypeptides, and recombinant DNA constructs, suppression DNA constructs and CRISPR/Cas9 DNA constructs are provided. Compositions (such as plants or seeds) with modified expression or activity of the isolated polypeptides are obtained by transforming the regenerable plant cell with a suppression DNA construct or CRISPR/Cas construct. The plants with improving drought tolerance are obtained by decreasing the expression or activity of the isolated polynucleotide.

Abstract: Exemplary embodiments of the present disclosure relate to methods of manufacturing display panels and display panels. The method of manufacturing a display panel includes: preparing a driving film layer on a substrate of the display panel, and removing at least a removal part of the driving film layer along a slotting-cutting path of the display panel; performing a cutting process on a slotted area of the display panel along the slotting-cutting path. By removing at least a removal part of the driving film layer along the slotting-cutting path before performing the cutting process on the slotted area of the display panel, problems such as thermal damage to the driving film layer and the like can be prevented, so that the problem of reducing the strength of the screen body in the slotted area can be avoided, and the quality of the product can be improved.