Abstract: Disclosed is a die-bonding method which provides a target substrate having a circuit structure with multiple electrical contacts and multiple semiconductor elements each semiconductor element having a pair of electrodes, arranges the multiple semiconductor elements on the target substrate with the pair of electrodes of each semiconductor element aligned with two corresponding electrical contacts of the target substrate, and applies at least one energy beam to join and electrically connect the at least one pair of electrodes of every at least one of the multiple semiconductor elements and the corresponding electrical contacts aligned therewith in a heating cycle by heat carried by the at least one energy beam in the heating cycle. The die-bonding method delivers scattering heated dots over the target substrate to avoid warpage of PCB and ensures high bonding strength between the semiconductor elements and the circuit structure of the target substrate.

Abstract: This invention provides antibodies directed against a highly specific and previously unrecognized marker for cancerous cells. In certain embodiments an isolated antibody or fragment thereof that specifically binds human placentally expressed ALPP and/or ALPPL2, but not ALPL and ALPI that are expressed outside the placenta is provided as well as immunoconjugates comprising such antibodies.

Abstract: This application discloses an antenna gain apparatus and a communication device. The antenna gain apparatus includes a first guiding portion and a second guiding portion. The first guiding portion is configured to be disposed at one side of an antenna radiating element in a first direction; and the second guiding portion is disposed on the first guiding portion, where the second guiding portion is located at one side of the first guiding portion in the first direction, and a shape of the second guiding portion matches a shape of the antenna radiating element.

Abstract: A method to upregulate CD46 cell surface expression and combination therapies for various cancers employing an anti-CD46 antibody, an androgen signaling inhibitor (ASI), a STAT3 inhibitor and/or a glucocorticoid receptor agonist or modular (SEGRAM) are provided.

Abstract: A curing agent comprising a polyetheramine, a tertiary amine substantially free of an aromatic tertiary amine and glycerin. The curing agent may be combined with an epoxy resin to form a curable composition which is capable of being applied to a substrate and cured to form a cured article.

Abstract: Antibodies are provided herein that agonize Wnt signaling, do not compete with a Wnt ligand for LRP6 binding, and activate Wnt signaling in the presence of inhibitors. Methods for promoting cell differentiation and tissue regeneration using the disclosed antibodies are also provided.

Abstract: A blood sample platelet uniform-mixing device for a blood analyzer includes a vortex oscillation device, the vortex oscillation device includes a fixing assembly, a rotating assembly and a vibrating assembly. The fixing assembly is used for fixing sample test tubes. The rotating assembly includes a rotating motor and a rotating disc. A rotating shaft of the rotating motor is connected with the rotating disc, the rotating disc is matched with the fixing assembly. A central axis of each of the sample test tubes fixed on the fixing assembly deviates from the rotating shaft of the rotating motor. The rotating assembly is used for rotating the fixing assembly and making a blood sample in each of the sample test tubes be in a vortex shape. The vibrating assembly is arranged on the fixing assembly.

Abstract: A quartz crystal resonator including a quartz crystal obtained from a quartz bar is provided. The quartz bar has a light axis, an electrical axis along a length of the quartz bar, and a mechanical axis that are perpendicular to one another. The quartz crystal has a major face cut from the quartz bar along a cutting plane. The cutting plane has a first angle of about 35° to about 36° with the light axis and has a second angle with the electric axis. The first angle is obtained by rotation about the electric axis, and the second angle is obtained by rotation about the light axis, such that the quartz crystal has a vibration frequency deviation inflection point in a range from about 30° C. to about 45° C. Methods for making the quartz crystal are also provided.

Abstract: Leave-on oral care compositions including a hyaluronic acid or a salt thereof good spreadability and improved retention period are provided for promoting Gum Health of a user. Kits and methods are also provided.

Abstract: Leave-on oral care compositions having good spreadability and improved retention property are provided for promoting Gum Health of a user. Leave-on oral care compositions can comprise a hyaluronic acid or a salt thereof, a polyacrylic acid as a mucoadhesive polymer, and an additional polymer.

Abstract: A method to upregulate CD46 cell surface expression and combination therapies for various cancers employing an anti-CD46 antibody and an immunomodulatory imide drug (IMiD) or a Signal Transducer And Activator of Transcription 3 (STAT3) inhibitor or both are provided.

Abstract: Leave-on oral care compositions comprising a hyaluronic acid and a gum-strengthening polyol are provided for promoting Gum Health of a user.

Abstract: The present disclosure relates to an engineered antibody that co-engages a cell type-selective (or specific) antigen (guide) and a signaling receptor (effector) on a target cell. In some instances, the engineered antibody is capable of modulating a signaling pathway on a target cell. In other embodiments, an engineered antibody of the present disclosure is administered to a subject for the treatment of a disease or condition.

Abstract: Leave-on oral care compositions comprising a hyaluronic acid or a salt thereof having good spreadability and improved retention period are provided for promoting Gum Health of a user.

Abstract: A die including a first contact with a first shape (e.g., ring-shaped) and a second contact with a second shape (e.g., cylindrical shaped) different from the first shape. The first contact has an opening that extends through a central region of a surface of the first contact. A first solder portion is coupled to the surface of the first contact and the first solder portion has the first shape. A second solder portion is coupled to a surface of the second contact and the second solder portion has the second shape. The first solder portion and the second solder portion both have respective points furthest away from a substrate of the die. These respective points of the first solder portion and the second solder portion are co-planar with each other such that a standoff height of the die remains consistent when coupled to a PCB or an electronic component.

Abstract: Leave-on oral care compositions having good spreadability and improved retention property are provided for promoting Gum Health of a user. Said leave-on oral care compositions comprise a hyaluronic acid or a salt thereof, a polyacrylic acid as a mucoadhesive polymer and an additional polymer.

Abstract: Leave-on oral care compositions comprising a hyaluronic acid, and a gum-strengthening polyol are provided for promoting Gum Health of a user.

Abstract: A fuel system, comprising at least one fuel component formed of a steel alloy comprising 0.01-0.31 wt. % carbon, 0.0-0.20 wt. % silicon, 0.15-0.50 wt. % manganese, 0.0-0.015 wt. % phosphorous, 0.0-0.001 wt. % sulfur, 4.80-5.20 wt. % chromium, 4.80-6.20 wt. % nickel, 0.60-0.80 wt. % molybdenum, 0.0-0.550 wt. % vanadium, and 2.000-2.400 wt. % aluminum, wherein the at least one fuel component is configured to come in contact with fuel when fuel is ran through the fuel system.

Abstract: Disclosed herein are system, method, and computer program product embodiments for providing offline capabilities to customizable live applications in a cloud collaboration platform. The cloud collaboration platform may provide offline functions and a data application programming interface to devices connecting to the cloud collaboration platform. The offline capabilities allow devices to store data related to documents and customizable live applications in a local cache. The offline capabilities retrieve data from and store modifications to data within the local cache. The cloud collaboration platform may subsequently process the changes and determine if conflicts arise, resolving conflicts where appropriate and possible. The cloud collaboration platform may then determine a final state for a record, return the final state to the devices, and update the local caches.

Abstract: Disclosed is a die-bonding method which provides a target substrate having a circuit structure with multiple electrical contacts and multiple semiconductor elements each semiconductor element having a pair of electrodes, arranges the multiple semiconductor elements on the target substrate with the pair of electrodes of each semiconductor element aligned with two corresponding electrical contacts of the target substrate, and applies at least one energy beam to join and electrically connect the at least one pair of electrodes of every at least one of the multiple semiconductor elements and the corresponding electrical contacts aligned therewith in a heating cycle by heat carried by the at least one energy beam in the heating cycle. The die-bonding method delivers scattering heated dots over the target substrate to avoid warpage of PCB and ensures high bonding strength between the semiconductor elements and the circuit structure of the target substrate.