Abstract: Provided herein is a photoresponsive prodrug comprising an active agent conjugated to a photoresponsive group, and a nanoparticle, wherein the photoresponsive prodrug is co-assembled with a polymer to form a nanoparticle. Also provided is a method of treating a subject, comprising administering photoresponsive prodrug or the nanoparticle to the subject, and irradiating at the target site with a light source.

Abstract: The present disclosure is directed to medical devices and provides a temperature control method, device, electronic device, and computer-readable storage medium for a pulmonary artery radio frequency ablation system. The radio frequency ablation system can comprise a radio frequency power source, an ablation electrode and a temperature sensing wire coupled with the ablation electrode. The method can comprise, during each of a plurality of ablation cycles, obtaining a current temperature measurement value measured by the temperature sensing wire and comparing the current temperature measurement value with a preset target temperature.

Abstract: A display substrate includes a base substrate, multiple sub-pixels, multiple first gate drive circuits, and at least one auxiliary structure. The base substrate includes a display region and a peripheral region located at a periphery of the display region. The multiple sub-pixels are located in the display region. The multiple first gate drive circuits and the at least one auxiliary structure are located in the peripheral region. The multiple first gate drive circuits are configured to provide first gate drive signals to the multiple sub-pixels. One auxiliary structure is disposed between adjacent first gate drive circuits.

Abstract: A purification method for detection of a strontium isotope in a silk cultural relic. The method includes: (1) enrichment of the strontium isotope: after cleaning the silk cultural relic, adding the silk cultural relic to a digestion agent for microwave digestion, and conducting evaporation drying; and adding a dried product to a nitric acid solution for centrifugal separation, and extracting a supernatant; and (2) purification of the strontium isotope: first, mixing 4?,4?(5?)-di-tert-butyldicyclohexano-18-crown-6 and a defoamer and adsorbed to a purified resin separation column, and pre-cleaning the purified resin separation column with a nitric acid solution; next, injecting the supernatant in step (1) into the purified resin separation column with a nitric acid solution as a carrier solution; and then, injecting an 84Sr solution and an elution solution into the purified resin separation column in sequence to obtain a separated and purified strontium solution.

Abstract: An image processing method and device, an equipment, and a computer-readable storage medium are provided. The method includes the following. An image is obtained. Object detection is performed on the image with an object detection network to obtain an object detection result. The object detection network is a network obtained by performing object detection on sample images in a sample image set based on at least one cluster center value with an initial object detection network and training iteratively the initial object detection network based on results of the object detection. The at least one cluster center value is obtained by clustering labeled regions in a labeled region set corresponding to the sample image set based on preset attribute information. The image is processed based on the object detection result.

Abstract: A display substrate includes at least two barrier layers in a peripheral area of the display substrate. The at least two barrier layers includes a first barrier layer forming an enclosure; and a third barrier layer on a side of the first barrier layer closer to a display area. The third barrier layer includes one or more discontinuous portions.

Abstract: A method of manufacturing an IC structure includes configuring each of an n-well and a p-well in a first IC die to have a first portion extending in a first direction and second and third portions extending from the first portion in a second direction perpendicular to the first direction, and forming IC devices including a first pickup structure electrically connected to the n-well and a second pickup structure electrically connected to the p-well. Forming the IC devices includes forming a PMOS transistor in the second or third portion of the n-well and forming an NMOS transistor in the second or third portion of the p-well.

Abstract: A display panel, including an active area and a peripheral area, which is located outside of the active area, wherein the active area comprises a base substrate, and a display structure layer and a touch structure layer sequentially arranged on the base substrate; the peripheral area includes an isolation dam, a first ground trace and a second ground trace arranged on the base substrate; and the first ground trace is located at a side of the isolation dam close to the active area, and the second ground trace is located at a side of the isolation dam away from the active area.

Abstract: An integrated circuit (IC) device includes at least one circuit having an input and an output, and an output connector electrically coupled to the output. The circuit further includes a plurality of transistors electrically coupled with each other between the input and the output. The output is in a first metal layer. The output connector includes a first conductive pattern in the first metal layer, and a second conductive pattern in a second metal layer different from the first metal layer. The second conductive pattern electrically couples the output to the first conductive pattern.

Abstract: A display substrate and a display device are provided. The display substrate includes sub-pixels including a light emitting element and a pixel circuit, the light emitting element includes a second electrode including a main body electrode. The sub-pixels include a first color sub-pixel which includes a first connecting portion. In the first color sub-pixel, the connecting electrode is connected with the first connecting portion through a first via hole, and the first connecting portion is electrically connected with the pixel circuit through a first connecting hole; and the first via hole and the first connecting hole are not overlapped with the main body electrode, and orthographic projections of the first via hole and the first connection hole on a first straight line extending in an extension direction of the data line are overlapped.

Abstract: The embodiments of the present disclosure disclose an object detection method and system, and a non-transitory computer-readable medium. In the object detection method, multiple candidate bounding boxes of an interest object in a current image frame are obtained. Based on a determined bounding box of the interest object in a previous image frame, the multiple candidate bounding boxes are filtered to obtain a determined bounding box of the interest object in the current image frame.

Abstract: A method, apparatus, non-transitory computer readable medium, and system for generating synthetic videos includes obtaining an input prompt describing a video scene. The embodiments then generate a plurality of frame-wise token embeddings corresponding to a sequence of video frames, respectively, based on the input prompt. Subsequently, embodiments generate, using a video generation model, a synthesized video depicting the video scene. The synthesized includes a plurality of images corresponding to the sequence of video frames.

Abstract: An evaluating method and a system for face verification, and a computer storage medium. The method comprises: obtaining a querying dataset and a training dataset, wherein the querying dataset comprises querying images, and the training dataset comprises training images; generating verification pairs and an evaluation list respectively according to the querying dataset and the training dataset; wherein the evaluation list comprises the querying images and the training images; determining feature information based on the evaluation list; establishing correspondences between identifiers and features according to first identifiers of the querying images, second identifiers of the training image, and the feature information; and determining evaluation results of the verification pairs according to the correspondences between the identifiers and the features.

Abstract: Disclosed are a display substrate and a display apparatus, wherein the display substrate may include a base substrate including a display region and a non-display region, and a drive circuit layer disposed on the base substrate, the drive circuit layer includes a pixel drive circuit located in the display region and a gate drive circuit located in the non-display region; a boundary of the display region includes an arc-shaped boundary, a non-display region located on an outside of the arc-shaped boundary is referred to as a rounded corner region, and the rounded corner region includes a plurality of first regions and at least one second region; the gate drive circuit is configured to provide a drive signal to the pixel drive circuit, and is partially located within a first region, and the second region is located between adjacent first regions.

Abstract: Described are a hand posture estimation method, an electronic device, and a non-transitory computer-readable storage medium. The method includes: obtaining an initial feature map corresponding to a hand region in a candidate image; obtaining a fused feature map by performing feature fusion processing on the initial feature map; wherein the feature fusion processing is configured to fuse features around a plurality of key points; the plurality of key points represent skeleton key nodes of the hand region; obtaining a target feature map by performing deconvolution processing on the fused feature map; wherein the deconvolution processing is configured to adjust a resolution of the fused feature map; and obtaining coordinate information of the plurality of key points based on the target feature map to determine a posture estimation result of the hand region in the candidate image.

Abstract: An integrated platform system that employ a series of machine learning techniques and prediction and detection units that can process input data and extract and generate meaningful insights and predictions therefrom. The system integrates together multiple different data storage types and applications that generates data of different types, and an associated processing system for processing the different data types, store the data in a common data model to normalize the data, determine the data lineage of the data, and then process the data using different types of techniques. The data can also be processed by a prediction unit for generating meaningful insights and predictions or by an anomaly detection unit for detecting one or more anomalies in the data.

Abstract: The invention provides for delivery, engineering and optimization of systems, methods and compositions for manipulation of sequences and/or activities of target sequences. Provided are delivery systems and tissues or organ which are targeted as sites for delivery. Also provided are vectors and vector systems some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells to ensure enhanced specificity for target recognition and avoidance of toxicity and to edit or modify a target site in a genomic locus of interest to alter or improve the status of a disease or a condition.

Abstract: An array substrate is provided. The array substrate includes a node connecting line in a same layer as a respective one of the plurality of voltage supply lines, connected to a first capacitor electrode through a first via, and connected to a semiconductor material layer through a second via; and an interference preventing block in a same layer as the second capacitor electrode. Along the first direction, a portion of the node connecting line at a position connecting to the semiconductor material layer through the second via is spaced apart from a first adjacent data line by a first arm, and is spaced apart from a second adjacent data line by a second arm.

Abstract: Disclosed are a display substrate and a preparation method therefor, and a display apparatus. The display substrate includes a plurality of circuit units, a plurality of data signal lines extending along a second direction, a plurality of first connection lines, and a plurality of second connection lines; a circuit unit includes a pixel drive circuit, at least one data signal line is connected with a plurality of pixel drive circuits of a unit column, first ends of the plurality of first connection lines are correspondingly connected with the plurality of data signal lines, and second ends of the plurality of first connection lines are correspondingly connected with the plurality of second connection lines; pixel drive circuits in adjacent unit columns are mirror symmetrical with respect to a center line, and a second connection line is disposed at a gap between pixel drive circuits in adjacent unit columns.

Abstract: The display substrate includes a plurality of circuit units, wherein at least one circuit unit includes a pixel drive circuit, the pixel drive circuit includes a storage capacitor and a plurality of oxide transistors, the storage capacitor includes a first capacitor plate and a second capacitor plate, and a capacitor insulating layer is arranged between the first capacitor plate and the second capacitor plate; and on a plane perpendicular to the display substrate, at least one circuit unit includes a semiconductor layer and a first source-drain metal layer arranged on a base substrate in a direction away from the base substrate, at least one capacitor insulating layer is arranged on a side of the semiconductor layer close to the base substrate, or at least one capacitor insulating layer is arranged on a side of the first source-drain metal layer away from the base substrate.