Abstract: Provided is a dual recombinant viral vector system for expressing, in a cell, a polypeptide molecule which is composed of two different peptide chains and has an antigen binding activity, wherein the first chain is expressed using a first viral vector, the second chain is expressed using a second viral vector, and the first and second chains can be assembled, after being expressed in a cell, into the polypeptide molecule which has an antigen binding activity. Further provided are a dual plasmid system for the production of the dual recombinant viral vector system, a host cell containing the dual recombinant viral vector system, a pharmaceutical composition, and the use of and the method for delivering the polypeptide molecule to a subject by using the dual recombinant viral vector system.

Abstract: The resource allocation method and apparatus are based on edge computing. The method includes: decomposing all application systems in a server into a plurality of meta-service units according to the coupling degree between different service modules in the application systems, and obtaining the quality of experience (QoE) index parameter value of each meta-service unit; clustering the plurality of meta-service units by using a clustering algorithm based on the QoE index parameter value of each meta-service unit; and allocating resources to each cluster according to the QoE index parameter values of all meta-service units in each cluster, so that all meta-service units in each cluster share the allocated resources. According to the invention, the resource allocation is more reasonable, the QoE value of a user is increased, and the resource use is more effective.

Abstract: An induced earthquake evaluation method for hydraulic fracturing activated faults includes obtaining an induced earthquake evaluation unit, cumulative injection equivalent energy, induced earthquake probability of fault type, induced earthquake probability of fault distance, hydraulic fracturing fluid diffusion capacity in fractured formation, new effective fault stress after fracturing, formation fluid pressure change rate and cumulative released equivalent energy. The probability of induced earthquake by hydraulic fracturing can be obtained. The induced earthquake possibility of each evaluation unit or single well under different stages of hydraulic fracturing, different construction injection methods and production conditions can be quantitatively evaluated. The method provides a quantitative result that can provide data support for optimizing hydraulic fracturing and reducing induced earthquake hazards.

Abstract: Disclosed is a pyridazinone compound represented by Formula (I), or a pharmaceutically acceptable salt, prodrug, hydrate, solvate, polymorph, stereoisomer, or isotopic variant thereof. The compound can be used for preparation of medicinal products for treatment and/or prophylaxis of a disease or condition associated with thyroid hormone abnormalities. The compound has higher selectivity to TH?, better pharmacokinetic parameters, desired stability, and higher agonistic activity toward TH?.

Abstract: A preparation method of a zeolite/polyimide composite membrane includes: synthesizing a zeolite-doped polyamic acid precursor casting solution by condensation polymerization synthesis; coating a substrate with the obtained casting solution, and obtaining a zeolite/polyamic acid composite porous membrane by non-solvent induced phase separation; and obtaining the zeolite/polyimide composite membrane by performing thermal imidization on the zeolite/polyamic acid composite porous membrane through gradient heating.

Abstract: A reactive power-voltage control method for integrated transmission and distribution networks is provided. The reactive power-voltage control method includes: establishing a reactive power-voltage control model for a power system consisting of a transmission network and a plurality of distribution networks; performing a second order cone relaxation on a non-convex constraint of the plurality of distribution network constraints to obtain the convex-relaxed reactive power-voltage control model; solving the convex-relaxed reactive power-voltage control model to acquire control variables of the transmission network and control variables of each distribution network; and controlling the transmission network based on the control variables of the transmission network and controlling each distribution network based on the control variables of the distribution network, so as to realize coordinated control of the power system.

Abstract: The disclosure provides an ultrasonic signal detection circuit including a sensing circuit, a unidirectional conduction circuit and a source follower circuit. The sensing circuit is connected to an input terminal of the source follower circuit through the unidirectional conduction circuit; the sensing circuit is configured to generate a piezoelectric signal according to a received ultrasonic echo signal and output the piezoelectric signal to the unidirectional conduction circuit. The piezoelectric signal is an alternating current signal; the unidirectional conduction circuit is configured to rectify the alternating current signal to only allow a forward or a reverse current portion thereof to pass through. The forward/reverse current portion charges/discharges the input terminal of the source follower circuit after passing through the unidirectional conduction circuit.

Abstract: A preparation method for and an application of a modified siloxane-based supercritical carbon dioxide thickener are disclosed. The method includes the following steps: using 1,3-diallyl-1,3,5-triazine-2,4,6-trione as a polymerization monomer, and dropwise adding 1,3,5,7-tetramethylcyclotetrasiloxane for hydrosilylation in the presence of a catalyst to obtain a modified siloxane polymer. The obtained modified siloxane polymer is directly used as a supercritical carbon dioxide thickener without purification post-treatment; when in use, the modified siloxane polymer is prepared into a solution with a concentration of 1-2%, has an excellent thickening effect with no cosolvent required, and has high solubility in carbon dioxide and high temperature resistance.

Abstract: A pollen polysaccharide extract prepared by the following method: mixing rape pollen with water, then heating and stirring for extraction, filtering, mixing filtrates, adding chitosan to a resulting filtrate to obtain a liquid to be clarified, keeping the liquid to be clarified at 60-80° C. for at least 1 h, cooling and allowing to stand, and performing solid-liquid separation to obtain a liquid, namely the pollen polysaccharide extract.

Abstract: A pollen polysaccharide extract prepared by the following method: mixing rape pollen with water, then heating and stirring for extraction, filtering, mixing filtrates, adding chitosan to a resulting filtrate to obtain a liquid to be clarified, keeping the liquid to be clarified at 60-80° C. for at least 1 h, cooling and allowing to stand, and performing solid-liquid separation to obtain a liquid, namely the pollen polysaccharide extract.

Abstract: A tabletop microphone assembly is provided that exhibits improved spatial audio pick-up characteristics, for example for use as an extension microphone for a conference system. In one embodiment, the tabletop microphone assembly comprises at least a housing with a top cover and a bottom cover, wherein the bottom cover is configured for placement on a table surface; a printed circuit board, arranged in the housing; and a microphone, arranged between the printed circuit board and the bottom cover; wherein the microphone is facing the bottom cover.

Abstract: A tabletop microphone assembly is provided that exhibits improved spatial audio pick-up characteristics, for example for use as an extension microphone for a conference system. In one embodiment, the tabletop microphone assembly comprises at least a housing with a top cover and a bottom cover, wherein the bottom cover is configured for placement on a table surface; a printed circuit board, arranged in the housing; and a microphone, arranged between the printed circuit board and the bottom cover; wherein the microphone is facing the bottom cover.

Abstract: Recommendations, such as recipients and attachments, are determined from content that is associated with a message item. A user may enter one or more: recipients; attachments; and message content for the message that may be used in determining recommendations. Keywords may also be identified by analyzing the content of the message to determine recommended content/recipients. Behavior patterns may also be used to determine recommendations. The recommended users/content of a message may be obtained from a messaging program, a local data store, a network data store, a cloud service, and the like. The recommended items (e.g. users/content) determined from analyzing the content are displayed such that they may be used by the user when editing the message item. The recommended items may be ranked by relevancy using metrics such as keywords, people, time last viewed and use patterns.

Abstract: Electronic messages are displayed as tiles. A tile may include a background related to the electronic message. For example, the background of a tile may be a preview of an attachment to the message. When the message includes an attachment (e.g. document, picture, link . . . ), an overlay is displayed over the background. The overlay includes information relating to the electronic message (i.e. subject, sender, time, message preview . . . ). When the message does not include an attachment then the tile may include all/portion of the content of the electronic message. For example, the tile may include the subject, sender, time stamp, and message content. A user may switch between different browsing experiences (e.g. conversation view, list view, strip view, . . . ). When a tile represents a conversation each sender within the conversation may be displayed on a tile along with a preview of the messages of the conversation (i.e. the most recent message).

Abstract: A first set of changes to a first version of a digital document, as compared to a baseline version of the document, can be detected. The first set of changes can include a first change to a page of the document in the first version of the document, as compared to the baseline version of the document. Also, a second set of changes to a second version of a document, as compared to the baseline version of the document, can be detected. The second set of changes can include a second change to the page of the document in the second version of the document, as compared to the baseline version of the document. A conflict between the first change and the second change can be detected, and the conflict can be resolved by receiving user input or applying conflict resolution rule(s) to choose between the first and second changes.

Abstract: A first set of changes to a first version of a digital document, as compared to a baseline version of the document, can be detected. The first set of changes can include a first change to a page of the document in the first version of the document, as compared to the baseline version of the document. Also, a second set of changes to a second version of a document, as compared to the baseline version of the document, can be detected. The second set of changes can include a second change to the page of the document in the second version of the document, as compared to the baseline version of the document. A conflict between the first change and the second change can be detected, and the conflict can be resolved by receiving user input or applying conflict resolution rule(s) to choose between the first and second changes.

Abstract: A first set of changes to a first version of a digital document, as compared to a baseline version of the document, can be detected. The first set of changes can include a first change to a page of the document in the first version of the document, as compared to the baseline version of the document. Also, a second set of changes to a second version of a document, as compared to the baseline version of the document, can be detected. The second set of changes can include a second change to the page of the document in the second version of the document, as compared to the baseline version of the document. A conflict between the first change and the second change can be detected, and the conflict can be resolved by receiving user input or applying conflict resolution rule(s) to choose between the first and second changes.

Abstract: The invention is directed to processes for synthesizing bicyclic nucleoside antiviral compounds and for synthesizing the intermediates used in the process. The invention is also directed to novel intermediate compounds useful in the process. The antiviral compounds are useful in the treatment of herpes zoster (i.e., varicella zoster virus, VZV, shingles) and for the prevention of post herpetic neuralgia (PHN) resulting from this viral infection.

Abstract: The invention is directed to processes for synthesizing bicyclic nucleoside antiviral compounds and for synthesizing the intermediates used in the process. The invention is also directed to novel intermediate compounds useful in the process. The antiviral compounds are useful in the treatment of herpes zoster (i.e., varicella zoster virus, VZV, shingles) and for the prevention of post herpetic neuralgia (PHN) resulting from this viral infection.