Abstract: An extrusion device of a three-dimensional printer includes a ratchet, a spray head, an idler, a feeding wheel and an optical detection mechanism. The spray head and the idler are disposed adjacent to the ratchet. A thermofusible material is provided to the spray head by the feeding wheel. The optical detection mechanism includes a guiding element and an optical detecting assembly. The guiding element is disposed between the ratchet and the feeding wheel along a feeding path. The optical detecting assembly is disposed adjacent to the guiding element. The thermofusible material is guided by the guiding element and partially disposed on a detecting area. A waveband light is emitted to the detecting area by the optical detecting assembly. The image produced by the reflection of the waveband light reflected by the detecting area is detected by the optical detecting assembly. Therefore, the operation of the equipment is completely monitored.

Abstract: The present invention pertains to a cell culture medium comprising hypotaurine, GABA, and/or beta-alanine or the combination of choline and hypotaurine, GABA, and/or beta-alanine as media supplements which is shown to control viability, growth, and waste byproduct accumulation. The present invention further pertains to a method of producing a polypeptide of interest in a large scale cell culture containing hypotaurine, GABA, and/or beta-alanine or the combination of choline and hypotaurine, GABA, and/or beta-alanine.

Abstract: A cleaning apparatus includes a combing unit including a series of spaced protrusions or teeth extending into a cleaning roller for preventing build up and removing debris (such as hair, string, and the like). The protrusions extend along a substantial portion of the cleaning roller and extend partially into the cleaning roller to intercept the debris as it passes around the roller. The protrusions have angled leading edges that are not aligned with a rotation center of the cleaning roller and are directed into or against a direction of rotation of the cleaning roller. The combing unit and protrusions have a shape and configuration designed to facilitate debris removal from the cleaning roller with minimal impact on the operation of the cleaning apparatus. The cleaning apparatus may include a surface cleaning head of an upright vacuum cleaner or sweeper or a robotic vacuum cleaner.

Abstract: An omnidirectional manipulator is provided for use with a spring forming machine and includes a tool module, a first linear guideway, a second linear guideway, and a third linear guideway. The first linear guideway supports, in a manner of being mounted thereon, and drives the tool module to move along a first linear axis. The second linear guideway supports, in a manner of being mounted thereon, and drives the first linear guideway to move along a second linear axis. The third linear guideway supports, in a manner of being mounted thereon, and drives the second linear guideway to move along a third linear axis. The first linear axis, the second linear axis, and the third linear axis are perpendicular to one another.

Abstract: A servo-rotating all-function tool module is provided for use with a spring forming machine and includes an axle rotating tool module and a servo transmission module assembly. The axle rotating tool module is mounted to the axle and includes an axle slide base and a tool, so that the axle slide base is acted upon by a force to slide along the axle, the tool is caused to press downward or return upward. The servo transmission module assembly is mounted to the spring forming machine to provide a driving force for causing the axle slide base to slide along the axle. Since the tool module is mounted to an axle mounted to a front wall board of the spring forming machine, the direction in which the tool approaches a wire can be varied by rotating the axle in order to conduct operations of bending at different angles and twisting/looping.

Abstract: The present invention pertains to methods of producing polypeptide of interest in cell cultures lacking glutamine. The present invention further pertains to a method of producing a protein of interest in a large scale cell culture, comprising supplementing the cell culture with nucleic acid synthesis precursors and/or corticosteroids.

Abstract: A stanchion capable of providing prompted information comprises a post and a prompt device disposed in the post. The prompt device senses the queuing state and outputs the prompted information corresponding to the queuing state. Hence, the stanchion offers information favorable for the queue such as waiting time and other helpful functions available for being applied to prompt people in the queue as well in addition to partitioning the moving line of the queue.

Abstract: The present invention pertains to a cell culture medium comprising media supplements that are shown to control recombinant protein glycosylation and/or cell culture in a controlled or modulated (shifted) temperature to control recombinant protein glycosylation and/or cell culture with controlled or modulated seed density to control recombinant protein glycosylation, and methods of using thereof. The present invention further pertains to a method of controlling or manipulating glycosylation of a recombinant protein of interest in a large scale cell culture.

Abstract: Methods of improving the efficiency of production of a protein product of interest in mammalian cell culture are presented. In particular, the methods result in an increase in the quantity of a protein product produced, or decreases protein product production time in a manufacturing-scale bioreactor cell culture. The disclosed methods comprise: (a) culturing the N-1 bioreactor culture to high viable cell densities; and (b) seeding the production bioreactor culture at high viable cell seeding densities.

Abstract: A display panel and a fabrication method thereof are provided. The display panel includes a substrate, a plurality of thin film transistor devices, color filters having different colors and a plurality of auxiliary color filter patterns. The thin film transistor devices and the color filters are disposed in corresponding pixel regions of the substrate, and each color filter layer has an opening uncovering one corresponding thin film transistor device. The auxiliary color filter patterns are respectively disposed in the openings of the color filter layers, and the auxiliary color filter patterns have the same light transmission spectrum.

Abstract: The present invention pertains to a cell culture medium comprising media supplements that are shown to control recombinant protein glycosylation and/or cell culture in a controlled or modulated (shifted) temperature to control recombinant protein glycosylation and/or cell culture with controlled or modulated seed density to control recombinant protein glycosylation, and methods of using thereof. The present invention further pertains to a method of controlling or manipulating glycosylation of a recombinant protein of interest in a large scale cell culture.

Abstract: A contact operating device for a bicycle includes a mount and two touch sensors. The mount is fixed to a handle bar or a brake lever base of the bicycle and has a touch surface and two touch-site indicating portions located on the touch surface. The touch sensors are installed on the touch surface of the mount and correspond to the touch-site indicating portions of the mount for detecting a touch motion from a cyclist of the bicycle and sending a sensing signal to a controller, so that the controller performs a desired operation according to the received sensing signal.

Abstract: A non-contact operating device for a bicycle includes a mount and two light sensors. The mount has two sensing portions, and each of the light sensors located in one of the sensing portions of the mount. For an operational need, a cyclist riding the bicycle can trigger one of the light sensors by moving his/her thumb to cover that light sensor, and the triggered light sensor sends a sensing signal correspondingly to a controller, so that the controller performs a desired operation according to the received sensing signal.

Abstract: The present invention relates to methods of reducing substitution of amino acids during the production of polypeptides of interest in mammalian cells. By varying the concentration of amino acids in the culture medium, heterogeneity of the polypeptide's amino acid sequence is decreased, leading to higher yields of functional protein.

Abstract: The present invention discloses a photo kiosk device. The photo kiosk device may include a housing with an extendable arm to provide a photo taking environment, a digital lens provided at one side of the housing to capture a photo image, a user interface provided at one side of the housing to display the captured photo image; and a photo slot provided at one side of the housing to output a finished photo product of the captured photo image, wherein the extendable arm, when extended, is provided with a back light source at a surface thereof to enhance a brightness of the photo taking environment.

Abstract: A method for treating a cell proliferative disorder in a subject is provided. The method for treating a cell proliferative disorder has a step of: administering a C1GALT1 inhibition substance to the subject for inhibiting C1GALT1 expression or activity in the subject, so as to treat the cell proliferative disorder in the subject.

Abstract: A semiconductor package structure includes a chip unit, a package unit and an electrode unit. The chip unit includes at least one semiconductor chip. The semiconductor chip has an upper surface, a lower surface, and a surrounding peripheral surface connected between the upper and the lower surfaces, and the semiconductor chip has a first conductive pad and a second conductive pad disposed on the lower surface thereof. The package unit includes a package body covering the upper surface and the surrounding peripheral surface of the semiconductor chip. The package body has a first lateral portion and a second lateral portion respectively formed on two opposite lateral sides thereof. The electrode unit includes a first electrode structure covering the first lateral portion and a second electrode structure covering the second lateral portion. The first and the second electrode structures respectively electrically contact the first and the second conductive pads.

Abstract: A semiconductor package structure includes a chip unit, a package unit and an electrode unit. The chip unit includes at least one semiconductor chip. The semiconductor chip has an upper surface, a lower surface, and a surrounding peripheral surface connected between the upper and the lower surfaces, and the semiconductor chip has a first conductive pad and a second conductive pad disposed on the lower surface thereof. The package unit includes a package body covering the upper surface and the surrounding peripheral surface of the semiconductor chip. The package body has a first lateral portion and a second lateral portion respectively formed on two opposite lateral sides thereof. The electrode unit includes a first electrode structure covering the first lateral portion and a second electrode structure covering the second lateral portion. The first and the second electrode structures respectively electrically contact the first and the second conductive pads.

Abstract: The present invention relates to a vibration energy harvest device. In the present invention, the vibration energy harvest device is provided for being used to recycle the mechanical energy and thermal energy generated during the vibration, and effectively to improve the power generation efficiency with newly added hydraulic motor and electricity generating unit. Wherein by using an ameliorating valve module and removing the damping hole in the prior art, no matter the damping oil flows from inner cylinder module through hydraulic motor to outer cylinder module or the contrary direction, the flowing damping oil could avoid the hydraulic motor from reciprocating to improve the power generation efficiency.

Abstract: A proportional electromagnet includes a cylindrical shell, first and second covers connected to two ends of the shell by riveting, a metal core inserted through an axial defined in the second cover and formed with a first section located in the shell and a second section located outside the shell, a coil unit provided between the shell and the metal core, a supporting element provided on the first section of the metal core, a bushing provided on the second section of the metal core, a copper ring provided on the first section of the metal core to improve magnetic thrust of the proportional electromagnet, a stop provided on the first section of the metal core, and a magnetic shield provided between the first section of the metal core and the coil unit to direct magnetic flux toward the supporting element and the metal core to stably drive the metal core.