Patents by Inventor Yasheen Zhou

Yasheen Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220273683
    Abstract: Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed.
    Type: Application
    Filed: December 24, 2020
    Publication date: September 1, 2022
    Applicant: Bill & Melinda Gates Foundation
    Inventors: Xianfeng LI, Christopher S. LUNDE, Robert T. JACOBS, Yasheen ZHOU
  • Publication number: 20220242886
    Abstract: The present invention describes novel compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the invention have activity as Janus kinase (JAK) inhibitors and are useful in the in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described herein are methods of treating inflammation, auto-immune diseases, cancer, and other conditions susceptible to inhibition of JAK by administering a compound herein described.
    Type: Application
    Filed: February 1, 2022
    Publication date: August 4, 2022
    Inventors: Yasheen ZHOU, Chunliang LIU, Yong-Kang ZHANG, Marissa AUBREY, Chun Yu LIU
  • Publication number: 20220194965
    Abstract: The present invention describes novel boron containing pyrazole compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the invention have activity as Janus kinase (JAK) inhibitors and are useful in the in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described are methods of treating inflammation, auto-immune diseases, cancer, and other conditions that are susceptible to the inhibition of a Janus kinase by administering a compound herein described.
    Type: Application
    Filed: December 13, 2021
    Publication date: June 23, 2022
    Inventors: Alan LONG, Chun Yu LIU, Chunliang LIU, Yasheen ZHOU, Shon R. PULLEY, Keith Andrew Newton GRAHAM
  • Patent number: 11306108
    Abstract: The present invention describes novel compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the invention have activity as Janus kinase (JAK) inhibitors and are useful in the in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described herein are methods of treating inflammation, auto-immune diseases, cancer, and other conditions susceptible to inhibition of JAK by administering a compound herein described.
    Type: Grant
    Filed: December 23, 2020
    Date of Patent: April 19, 2022
    Assignee: Borah, Inc.
    Inventors: Yasheen Zhou, Chunliang Liu, Yong-Kang Zhang, Marissa Aubrey, Chun Yu Liu
  • Publication number: 20210188879
    Abstract: The present invention describes novel compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the invention have activity as Janus kinase (JAK) inhibitors and are useful in the in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described herein are methods of treating inflammation, auto-immune diseases, cancer, and other conditions susceptible to inhibition of JAK by administering a compound herein described.
    Type: Application
    Filed: December 23, 2020
    Publication date: June 24, 2021
    Inventors: Yasheen ZHOU, Chunliang LIU, Yong-Kang ZHANG, Marissa AUBREY, Chun Yu LIU
  • Publication number: 20210069219
    Abstract: The present invention relates to boron containing compounds of Formula (I) X—Y—Z?? Formula (I) that inhibit phosphodiesterase 4 (PDE4). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating diseases, conditions, or disorders ameliorated by inhibition of PDE4.
    Type: Application
    Filed: October 28, 2020
    Publication date: March 11, 2021
    Applicant: Pfizer Inc.
    Inventors: Joseph Walter Strohbach, Tsutomu Akama, David Clive Blakemore, Robert Toms Jacobs, Peter Jones, David Christopher Limburg, Martins Sunday Oderinde, Matthew Alexander Perry, Jacob John Plattner, Rubben Federico Torella, Yasheen Zhou, Thean Yeow Yeoh
  • Patent number: 10874679
    Abstract: Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed.
    Type: Grant
    Filed: April 3, 2020
    Date of Patent: December 29, 2020
    Assignee: Bill & Melinda Gates Foundation
    Inventors: Xianfeng Li, Christopher S Lunde, Robert T Jacobs, Yasheen Zhou
  • Publication number: 20200385409
    Abstract: A benzoxaborole formulation composition including a benzoxaborole, a non-ionic surfactant, or a non-ionic and ionic surfactant mixture, and a carrier is described herein. At least one of the non-ionic surfactant, the non-ionic and ionic surfactant mixture, and the carrier comprise a Lewis base or a N—H or O—H bond. The carrier is a solid or a liquid. Benzoxaborole compounds and methods of using the compounds and formulations of the compounds are described. For example, a method for reducing, preventing, ameliorating, or inhibiting an infestation by a pathogen by applying a compound or a formulation of a compound, wherein the pathogen is selected from insects, nematodes, bacteria, microbes, fungi, protozoa, viruses, and parasites, or any combinations thereof is described.
    Type: Application
    Filed: November 30, 2018
    Publication date: December 10, 2020
    Inventors: Marissa AUBREY, Chun Yu LIU, Chunliang LIU, Michael SAMUELS, Yong-Kang ZHANG, Yasheen ZHOU
  • Publication number: 20200230160
    Abstract: Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed.
    Type: Application
    Filed: April 3, 2020
    Publication date: July 23, 2020
    Applicant: Bill and Melinda Gates Foundation
    Inventors: Xianfeng LI, Christopher S. LUNDE, Robert T. JACOBS, Yasheen ZHOU
  • Publication number: 20200108083
    Abstract: The present invention relates to boron containing compounds of Formula (I) X—Y—Z?? Formula (I) that inhibit phosphodiesterase 4 (PDE4). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating diseases, conditions, or disorders ameliorated by inhibition of PDE4.
    Type: Application
    Filed: October 4, 2019
    Publication date: April 9, 2020
    Applicant: Pfizer Inc.
    Inventors: Joseph Walter Strohbach, Tsutomu Akama, David Clive Blakemore, Robert Toms Jacobs, Peter Jones, David Christopher Limburg, Martins Sunday Oderinde, Matthew Alexander Perry, Jacob John Plattner, Rubben Federico Torella, Yasheen Zhou, Thean Yeow Yeoh
  • Patent number: 10611781
    Abstract: Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: April 7, 2020
    Assignee: Bill and Melinda Gates Foundation
    Inventors: Xianfeng Li, Christopher S. Lunde, Robert T. Jacobs, Yasheen Zhou
  • Publication number: 20190185493
    Abstract: Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed.
    Type: Application
    Filed: February 27, 2017
    Publication date: June 20, 2019
    Inventors: Xianfeng Li, Christopher S. Lunde, Robert T. Jacobs, Yasheen Zhou
  • Patent number: 9617285
    Abstract: Provided are compounds useful for controlling endoparasites both in animals and agriculture. Further provided are methods for controlling endoparasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling endoparasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: April 11, 2017
    Assignees: ELI LILLY AND COMPANY, ANACOR PHARMACEUTICALS, INC.
    Inventors: Tsutomu Akama, Kurt Jarnagin, Jacob J. Plattner, Shon Roland Pulley, William Hunter White, Yong-Kang Zhang, Yasheen Zhou
  • Patent number: 9493490
    Abstract: This invention provides novel compounds of the following formula and pharmaceutical compositions containing such compounds.
    Type: Grant
    Filed: July 22, 2014
    Date of Patent: November 15, 2016
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Tsutomu Akama, Kurt Jarnagin, Yong-Kang Zhang, Yasheen Zhou, Jacob J. Plattner, David C. Sullivan
  • Patent number: 9346834
    Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
    Type: Grant
    Filed: October 19, 2010
    Date of Patent: May 24, 2016
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Huchen Zhou, Dazhong Ding, Daoan Sun, Yasheen Zhou, Yong-Kang Zhang, Jacob J. Plattner
  • Publication number: 20160000813
    Abstract: This invention provides novel compounds, methods of using the compounds, and pharmaceutical formulations comprising the compounds.
    Type: Application
    Filed: September 11, 2015
    Publication date: January 7, 2016
    Inventors: Tsutomu AKAMA, Terry William Balko, Jean Marie Defauw, Jacob J. Plattner, William Hunter White, Joseph Raymond Winkle, Yong-Kang Zhang, Yasheen Zhou
  • Publication number: 20150353581
    Abstract: Provided are compounds useful for controlling endoparasites both in animals and agriculture. Further provided are methods for controlling endoparasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling endoparasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier.
    Type: Application
    Filed: March 6, 2014
    Publication date: December 10, 2015
    Applicant: Eli Lilly and Company
    Inventors: Tsutomu Akama, Kurt Jarnagin, Jacob J. Plattner, Shon Roland Pulley, William Hunter White, Yong-Kang Zhang, Yasheen Zhou
  • Patent number: 9156860
    Abstract: This invention provides novel compounds, methods of using the compounds, and pharmaceutical formulations comprising the compounds.
    Type: Grant
    Filed: October 6, 2014
    Date of Patent: October 13, 2015
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Tsutomu Akama, Terry William Balko, Jean Marie Defauw, Jacob J. Plattner, William Hunter White, Joseph Raymond Winkle, Yong-Kang Zhang, Yasheen Zhou
  • Publication number: 20150025038
    Abstract: This invention provides novel compounds, methods of using the compounds, and pharmaceutical formulations comprising the compounds.
    Type: Application
    Filed: October 6, 2014
    Publication date: January 22, 2015
    Inventors: Tsutomu AKAMA, Terry William Balko, Jean Marie Defauw, Jacob J. Plattner, William Hunter White, Joseph Raymond Winkle, Yong-Kang Zhang, Yasheen Zhou
  • Patent number: 8853186
    Abstract: This invention provides novel compounds, methods of using the compounds, and pharmaceutical formulations comprising the compounds.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: October 7, 2014
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Tsutomu Akama, Terry William Balko, Jean Marie Defauw, Jacob J. Plattner, William Hunter White, Joseph Raymond Winkle, Yong-Kang Zhang, Yasheen Zhou