Patents by Inventor Yasheen Zhou

Yasheen Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-Amino-7,8-dihydro-6H-pyrido[4,3-D]pyrimidin-5-ones
    Publication number: 20100004237
    Abstract: Disclosed are 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, their stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent. Disclosed also are methods of using the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cellular proliferative, viral, autoimmune, cardiovascular, and central nervous system diseases.
    Type: Application
    Filed: July 31, 2009
    Publication date: January 7, 2010
    Inventors: Timothy D. Machakewski, Cynthia M. Shafer, Christopher McBride, William Antonios-McCrea, Brandon M. Doughan, Barry H. Levine, Yi Xia, Maureen McKenna, X. Michael Wang, Kris Mendenhall, Yasheen Zhou, Baoqing Gong, Dan Gu, John Dolan, John Tulinsky, Kristin Brinner, Zhenhai Gao, Daniel Poon, Paul Barsanti, Xiaodong Lin, Abran Costales, Alice Rico, Nathan Brammeier, Teresa Pick, Paul A. Renhowe
  • Substituted 2,5-heterocyclic derivatives
    Patent number: 7470701
    Abstract: The present invention relates to new substituted five-membered compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds.
    Type: Grant
    Filed: March 30, 2005
    Date of Patent: December 30, 2008
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Xiaodong Lin, Alice Rico, Xiaojing Michael Wang, Yasheen Zhou, Ann B. Jefferson, Annette Walter
  • SUBSTITUTED 2,5-HETEROCYCLIC DERIVATIVES
    Publication number: 20080255120
    Abstract: The present invention relates to new substituted five-membered compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds.
    Type: Application
    Filed: May 29, 2008
    Publication date: October 16, 2008
    Applicant: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Xiaodong Lin, Alice Rico, Xiaojing Michael Wang, Yasheen Zhou, Ann B. Jefferson, Annette Walter
  • 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-ones
    Publication number: 20070123546
    Abstract: Disclosed are 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, their stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent. Disclosed also are methods of using the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cellular proliferative, viral, autoimmune, cardiovascular, and central nervous system diseases.
    Type: Application
    Filed: September 28, 2006
    Publication date: May 31, 2007
    Inventors: Timothy Machajewski, Cynthia Shafer, Christopher McBride, William Antonios-McCrea, Brandon Doughan, Barry Levine, Yi Xia, Maureen McKeena, X. Wang, Kris Mendenhall, Yasheen Zhou, Baoquing Gong, Dan Gu, John Dolan, John Tulinsky, Kristin Brinner, Zhenhai Gao
  • 2-Amino-quinazolin-5-ones
    Publication number: 20070027150
    Abstract: 2-Amino-quinazolin-5-one compounds, stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-quinazolin-5-one compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the 2-amino-quinazolin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cell proliferative diseases.
    Type: Application
    Filed: April 14, 2006
    Publication date: February 1, 2007
    Inventors: Cornelia Bellamacina, Abran Costales, Brandon Doughan, Susan Fong, Zhenhai Gao, Thomas Hendrickson, Barry Levine, Xiaodong Lin, Timothy Machajewski, Christopher McBride, William Antonios-McCrea, Maureen McKenna, Kris Mendenhall, Alice Rico, Cynthia Shafer, X. Wang, Yi Xia, Yasheen Zhou
  • Indolocarbazole anticancer agents and methods of using same
    Patent number: 7122526
    Abstract: The present invention relates to anti-tumor compounds, compositions and methods.
    Type: Grant
    Filed: June 30, 2003
    Date of Patent: October 17, 2006
    Assignee: Nanosphere, Inc.
    Inventors: Ze-Qi Xu, Yasheen Zhou, Michael T. Flavin
  • Substituted 2,5-heterocyclic derivatives
    Publication number: 20050256121
    Abstract: The present invention relates to new substituted five-membered compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds.
    Type: Application
    Filed: March 30, 2005
    Publication date: November 17, 2005
    Applicant: Chiron Corporation
    Inventors: Anne Jefferson, Xiaodong Lin, Xiaojing Wang, Alice Rico, Annette Walter, Yasheen Zhou
  • Combination therapy with CHK1 inhibitors
    Publication number: 20050256157
    Abstract: Compounds of Structure I, and salts, tautomers, stereoisomers, and mixtures thereof may be used in methods of inhibiting checkpoint kinase 1 in subjects, in methods for inducing cell cycle progression, and in methods for increasing apoptosis in cells. Such compounds may be used to prepare pharmaceutical compositions and may be used in conjunction with DNA damaging agents.
    Type: Application
    Filed: January 21, 2005
    Publication date: November 17, 2005
    Inventors: Thomas Gesner, Paul Barsanti, Stephen Harrison, Zhi-Jie Ni, Nathan Brammeier, Yasheen Zhou, Vincent Le
  • Indolocarbazole anticancer agents and methods of using same
    Publication number: 20040077554
    Abstract: The present invention relates to anti-tumor compounds, compositions and methods. In particular, the invention relates to indolocarbazole analogues of the following general formulas that inhibit topoisomerase I activity.
    Type: Application
    Filed: June 30, 2003
    Publication date: April 22, 2004
    Applicant: Advanced Life Sciences, Inc.
    Inventors: Ze-Qi Xu, Yasheen Zhou, Michael T. Flavin
  • Indolocarbazole anticancer agents and methods of using them
    Patent number: 6605596
    Abstract: The present invention relates to anti-tumor compounds, compositions and methods.
    Type: Grant
    Filed: October 29, 2001
    Date of Patent: August 12, 2003
    Assignee: Advanced Life Sciences, Inc.
    Inventors: David E. Zembower, Yongping Xie, Yasheen Zhou
  • Indolocarbazole anticancer agents and methods of using them
    Publication number: 20030087842
    Abstract: The present invention relates to anti-tumor compounds, compositions and methods. In particular, the invention relates to indolocarbazole analogues of the following general formulas that inhibit topoisomerase I activity.
    Type: Application
    Filed: October 29, 2001
    Publication date: May 8, 2003
    Applicant: Advanced Life Sciences, Inc.
    Inventors: David E. Zembower, Yongping Xie, Yasheen Zhou