Patents by Inventor Yasuhisa Shiraishi

Yasuhisa Shiraishi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210107997
    Abstract: The present invention relates to a monoclonal antibody or antibody fragment thereof as a human IgG antibody including at least one lysine derivative in a constant region of the human IgG antibody; a modified antibody or antibody fragment thereof, wherein the lysine derivative is modified; a nucleic acid including a nucleotide sequence encoding the antibody or antibody fragment thereof; a vector including the nucleic acid; a transformed cell obtained by introducing the vector into a host cell; a method for producing the antibody or antibody fragment thereof; and a composition containing the antibody or antibody fragment thereof.
    Type: Application
    Filed: December 22, 2020
    Publication date: April 15, 2021
    Applicants: RIKEN, KYOWA KIRIN CO., LTD.
    Inventors: Kensaku Sakamoto, Kazumasa Ohtake, Yoshimi Yamaguchi, Shigeyuki Yokoyama, Tatsuo Yanagisawa, Akiko Matsumoto, Akifumi Kato, Yasuhisa Shiraishi, Kaname Kimura, Masakazu Homma
  • Patent number: 10906990
    Abstract: The present invention relates to a monoclonal antibody or antibody fragment thereof as a human IgG antibody including at least one lysine derivative in a constant region of the human IgG antibody; a modified antibody or antibody fragment thereof, wherein the lysine derivative is modified; a nucleic acid including a nucleotide sequence encoding the antibody or antibody fragment thereof; a vector including the nucleic acid; a transformed cell obtained by introducing the vector into a host cell; a method for producing the antibody or antibody fragment thereof; and a composition containing the antibody or antibody fragment thereof.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: February 2, 2021
    Assignees: RIKEN, KYOWA KIRIN CO., LTD.
    Inventors: Kensaku Sakamoto, Kazumasa Ohtake, Yoshimi Yamaguchi, Shigeyuki Yokoyama, Tatsuo Yanagisawa, Akiko Matsumoto, Akifumi Kato, Yasuhisa Shiraishi, Kaname Kimura, Masakazu Homma
  • Patent number: 10578922
    Abstract: This invention reduces or prevents a phenomenon where a screen close to a light source becomes yellowed. A liquid crystal display device includes a liquid crystal display panel and a backlight. The backlight includes a light guide plate 10 and white LEDs 21 arrayed in a first direction on a plane of incidence 11 of the light guide plate 10. The white LEDs 21 each includes, in the first direction on a light-emitting surface, a central area occupied by a blue spectrum more densely than at adjacent sides of the central area. Incident plane protrusions 111, each extending in a thickness direction of the light guide plate 10, are formed on a section corresponding to the area having the dense blue spectrum of each LED 21, at the plane of incidence 11 of the light guide plate 10.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: March 3, 2020
    Assignee: Japan Display Inc.
    Inventors: Yasuhisa Shiraishi, Tomohisa Onishi
  • Patent number: 10324249
    Abstract: A display device includes a prism sheet between a display cell and a light guiding plate. The prism sheet includes a plurality of prisms having a constant apex angle continuously arranged in a second direction on a surface thereof opposed to a light-exiting surface of the light guiding plate. Each of ridge lines of the prisms extends in a first direction. Each prism has a first inclined face on a side on which light from the light guiding plate is incident and a second inclined face on a side reflecting the incident light. An area of the first inclined face is made smaller than an area of the second inclined face, and an area of a light-emitting region in the prism sheet is made larger than an area of a non-light-emitting region.
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: June 18, 2019
    Assignee: Japan Display Inc.
    Inventors: Tetsuya Oshima, Masaki Nishikawa, Yasuhisa Shiraishi
  • Publication number: 20190127488
    Abstract: The present invention relates to a monoclonal antibody or antibody fragment thereof as a human IgG antibody including at least one lysine derivative in a constant region of the human IgG antibody; a modified antibody or antibody fragment thereof, wherein the lysine derivative is modified; a nucleic acid including a nucleotide sequence encoding the antibody or antibody fragment thereof; a vector including the nucleic acid; a transformed cell obtained by introducing the vector into a host cell; a method for producing the antibody or antibody fragment thereof; and a composition containing the antibody or antibody fragment thereof.
    Type: Application
    Filed: August 18, 2016
    Publication date: May 2, 2019
    Applicants: RIKEN, KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Kensaku SAKAMOTO, Kazumasa OHTAKE, Yoshimi YAMAGUCHI, Shigeyuki YOKOYAMA, Tatsuo YANAGISAWA, Akiko MATSUMOTO, Akifumi KATO, Yasuhisa SHIRAISHI, Kaname KIMURA, Masakazu HOMMA
  • Patent number: 10233246
    Abstract: The present invention relates to an antibody or antibody fragment comprising novel Cys residue, to which a hydrophilic macromolecular group or amphipathic macromolecular group can be bound at a high efficiency. In addition, the present invention relates to a monoclonal antibody modified product or an antibody fragment modified product in which cysteine residue is chemically modified.
    Type: Grant
    Filed: August 19, 2015
    Date of Patent: March 19, 2019
    Assignee: KYOWA HAKKO KIRIN CO., LTD
    Inventors: Motoo Yamasaki, Yasuhisa Shiraishi
  • Patent number: 10088624
    Abstract: To provide a thin liquid crystal display device featuring excellent color reproducibility. The liquid crystal display panel includes: a liquid crystal display panel outputting different colors on a per-pixel basis; and a backlight. The backlight includes: a light source; a light guide; a reflective sheet on a back side of the light guide; and a group of optical sheets including a wavelength converter and disposed between the liquid crystal display panel and the light guide. The wavelength converter has a structure where quantum dots are dispersed in a transparent medium. The wavelength converter is bonded to another optical medium by means of a diffusing adhesive. Nanoparticles for developing Rayleigh scattering are dispersed in the wavelength converter.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: October 2, 2018
    Assignee: Japan Display Inc.
    Inventors: Masaki Nishikawa, Tetsuya Ooshima, Yasuhisa Shiraishi, Masateru Morimoto
  • Publication number: 20180120645
    Abstract: This invention reduces or prevents a phenomenon where a screen close to a light source becomes yellowed. A liquid crystal display device includes a liquid crystal display panel and a backlight. The backlight includes a light guide plate 10 and white LEDs 21 arrayed in a first direction on a plane of incidence 11 of the light guide plate 10. The white LEDs 21 each includes, in the first direction on a light-emitting surface, a central area occupied by a blue spectrum more densely than at adjacent sides of the central area. Incident plane protrusions 111, each extending in a thickness direction of the light guide plate 10, are formed on a section corresponding to the area having the dense blue spectrum of each LED 21, at the plane of incidence 11 of the light guide plate 10.
    Type: Application
    Filed: December 26, 2017
    Publication date: May 3, 2018
    Inventors: Yasuhisa SHIRAISHI, Tomohisa Onishi
  • Patent number: 9885913
    Abstract: This invention reduces or prevents a phenomenon where a screen close to a light source becomes yellowed. A liquid crystal display device includes a liquid crystal display panel and a backlight. The backlight includes a light guide plate 10 and white LEDs 21 arrayed in a first direction on a plane of incidence 11 of the light guide plate 10. The white LEDs 21 each includes, in the first direction on a light-emitting surface, a central area occupied by a blue spectrum more densely than at adjacent sides of the central area. Incident plane protrusions 111, each extending in a thickness direction of the light guide plate 10, are formed on a section corresponding to the area having the dense blue spectrum of each LED 21, at the plane of incidence 11 of the light guide plate 10.
    Type: Grant
    Filed: October 22, 2015
    Date of Patent: February 6, 2018
    Assignee: Japan Display Inc.
    Inventors: Yasuhisa Shiraishi, Tomohisa Onishi
  • Publication number: 20170227701
    Abstract: To provide a thin liquid crystal display device featuring excellent color reproducibility. The liquid crystal display panel includes: a liquid crystal display panel outputting different colors on a per-pixel basis; and a backlight. The backlight includes: a light source; a light guide; a reflective sheet on a back side of the light guide; and a group of optical sheets including a wavelength converter and disposed between the liquid crystal display panel and the light guide. The wavelength converter has a structure where quantum dots are dispersed in a transparent medium. The wavelength converter is bonded to another optical medium by means of a diffusing adhesive. Nanoparticles for developing Rayleigh scattering are dispersed in the wavelength converter.
    Type: Application
    Filed: January 31, 2017
    Publication date: August 10, 2017
    Inventors: Masaki NISHIKAWA, Tetsuya OOSHIMA, Yasuhisa SHIRAISHI, Masateru MORIMOTO
  • Publication number: 20170059765
    Abstract: A display device includes a prism sheet between a display cell and a light guiding plate. The prism sheet includes a plurality of prisms having a constant apex angle continuously arranged in a second direction on a surface thereof opposed to a light-exiting surface of the light guiding plate. Each of ridge lines of the prisms extends in a first direction. Each prism has a first inclined face on a side on which light from the light guiding plate is incident and a second inclined face on a side reflecting the incident light. An area of the first inclined face is made smaller than an area of the second inclined face, and an area of a light-emitting region in the prism sheet is made larger than an area of a non-light-emitting region.
    Type: Application
    Filed: August 24, 2016
    Publication date: March 2, 2017
    Applicant: Japan Display Inc.
    Inventors: Tetsuya OSHIMA, Masaki NISHIKAWA, Yasuhisa SHIRAISHI
  • Patent number: 9520094
    Abstract: According to an aspect, a display device includes: an image display panel; and a planar light source including a light guide plate and an edge-lit light source, the light guide plate illuminating the image display panel from a back side, the edge-lit light source including a plurality of light sources arranged facing a plane of incidence; and a controller that controls luminance of each of the light sources independently. The controller stores therein, as lookup tables for the respective light sources, information on light intensity distributions of light that is incident on the light guide plate from the respective light sources and is emitted to a plane of the image display panel from the light guide plate, and controls a light quantity of each of the light sources based on information on an input signal of an image, and on the lookup tables.
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: December 13, 2016
    Assignee: Japan Display Inc.
    Inventors: Tsutomu Harada, Naoyuki Takasaki, Susumu Kimura, Yasuhisa Shiraishi
  • Publication number: 20160116667
    Abstract: This invention reduces or prevents a phenomenon where a screen close to a light source becomes yellowed. A liquid crystal display device includes a liquid crystal display panel and a backlight. The backlight includes a light guide plate 10 and white LEDs 21 arrayed in a first direction on a plane of incidence 11 of the light guide plate 10. The white LEDs 21 each includes, in the first direction on a light-emitting surface, a central area occupied by a blue spectrum more densely than at adjacent sides of the central area. Incident plane protrusions 111, each extending in a thickness direction of the light guide plate 10, are formed on a section corresponding to the area having the dense blue spectrum of each LED 21, at the plane of incidence 11 of the light guide plate 10.
    Type: Application
    Filed: October 22, 2015
    Publication date: April 28, 2016
    Inventors: Yasuhisa SHIRAISHI, Tomohisa ONISHI
  • Publication number: 20160039937
    Abstract: The present invention relates to an antibody or antibody fragment comprising novel Cys residue, to which a hydrophilic macromolecular group or amphipathic macromolecular group can be bound at a high efficiency. In addition, the present invention relates to a monoclonal antibody modified product or an antibody fragment modified product in which cysteine residue is chemically modified.
    Type: Application
    Filed: August 19, 2015
    Publication date: February 11, 2016
    Applicant: KYOWA HAKKO KIRIN CO., LTD
    Inventors: Motoo YAMASAKI, Yasuhisa SHIRAISHI
  • Patent number: 9194994
    Abstract: A liquid crystal display device includes: a light guide plate including a front surface, a back surface and an edge surface, the light guide plate being arranged such that the edge surface faces a light source, the light guide plate internally reflecting light incident from the edge surface and causing surface emission from the front surface; a liquid crystal display panel; and a reflective sheet arranged so as to face the back surface of the light guide plate. The back surface includes a first portion and a second portion. A surface of the second portion is located at a position recessed relatively from a surface of the first portion. The surface of the first portion is a rough surface. The surface of the second portion is a smooth surface. The reflective sheet is in contact with the first portion but avoids contact with the second portion.
    Type: Grant
    Filed: January 6, 2014
    Date of Patent: November 24, 2015
    Assignee: JAPAN DISPLAY INC.
    Inventors: Ken Kagabu, Yasuhisa Shiraishi, Yoshikazu Tanabe, Yoshihiro Nishimine
  • Patent number: 9150639
    Abstract: The present invention relates to an antibody or antibody fragment comprising novel Cys residue, to which a hydrophilic macromolecular group or amphipathic macromolecular group can be bound at a high efficiency. In addition, the present invention relates to a monoclonal antibody modified product or an antibody fragment modified product in which cysteine residue is chemically modified.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: October 6, 2015
    Assignee: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Motoo Yamasaki, Yasuhisa Shiraishi
  • Publication number: 20150109351
    Abstract: According to an aspect, a display device includes: an image display panel; and a planar light source including a light guide plate and an edge-lit light source, the light guide plate illuminating the image display panel from a back side, the edge-lit light source including a plurality of light sources arranged facing a plane of incidence; and a controller that controls luminance of each of the light sources independently. The controller stores therein, as lookup tables for the respective light sources, information on light intensity distributions of light that is incident on the light guide plate from the respective light sources and is emitted to a plane of the image display panel from the light guide plate, and controls a light quantity of each of the light sources based on information on an input signal of an image, and on the lookup tables.
    Type: Application
    Filed: October 21, 2014
    Publication date: April 23, 2015
    Inventors: Tsutomu Harada, Naoyuki Takasaki, Susumu Kimura, Yasuhisa Shiraishi
  • Patent number: 8992062
    Abstract: Provided is a display device including: a light guide plate arranged so that an edge surface thereof is opposed to a light source, the light guide plate being configured to internally reflect light entering from the edge surface to cause planar light emission from a front surface of the light guide plate; and a reflective sheet arranged so as to be opposed to a rear surface of the light guide plate. Irregularities are formed on the front surface. The irregularities are formed to have a shape of a combination of first convex portions and second convex portions, each of the first convex portions including a first ridge line which continuously extends along a first direction corresponding to a light traveling direction, each of the second convex portions including a second ridge line which continuously extends along a second direction intersecting the first direction.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: March 31, 2015
    Assignee: Japan Display Inc.
    Inventors: Kentaro Oku, Yasuhisa Shiraishi, Masao Uehara, Akiyoshi Tobe, Takashi Kuwabara
  • Patent number: 8882324
    Abstract: A lighting device includes a light source 30, a light guide 20 provided adjacent to the light source 30 and including a light source light incident surface 21 on which light emitted by the light source 30 enters and a planar light emission surface 22 from which planar light is emitted, and an optical sheet 50 including a planar light incident surface 53 on which the planar light enters, and configured to change a traveling direction of the planar light because a light emission side of the optical sheet 50 has a shape in which plural columnar prisms 51 extending in parallel to the light source light incident surface 21 are arranged side by side. In each of the prisms 51, a distal surface has at least different two kinds of inclination angles.
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: November 11, 2014
    Assignee: Japan Display Inc.
    Inventors: Masaya Adachi, Akiyoshi Tobe, Yasuhisa Shiraishi
  • Publication number: 20140192293
    Abstract: A liquid crystal display device includes: a light guide plate including a front surface, a back surface and an edge surface, the light guide plate being arranged such that the edge surface faces a light source, the light guide plate internally reflecting light incident from the edge surface and causing surface emission from the front surface; a liquid crystal display panel; and a reflective sheet arranged so as to face the back surface of the light guide plate. The back surface includes a first portion and a second portion. A surface of the second portion is located at a position recessed relatively from a surface of the first portion. The surface of the first portion is a rough surface. The surface of the second portion is a smooth surface. The reflective sheet is in contact with the first portion but avoids contact with the second portion.
    Type: Application
    Filed: January 6, 2014
    Publication date: July 10, 2014
    Applicant: Japan Display Inc.
    Inventors: Ken KAGABU, Yasuhisa SHIRAISHI, Yoshikazu TANABE, Yoshihiro NISHIMINE