Patents by Inventor Yasushi Saito

Yasushi Saito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130115229
    Abstract: Provided is a detection method for a malignant tumor cell, including measuring a protein marker expressed on a malignant tumor cell surface. The detection method for a malignant tumor cell includes measuring LR11 on a cell surface in a sample to be tested.
    Type: Application
    Filed: July 15, 2011
    Publication date: May 9, 2013
    Applicant: Sekisui Medical Co., Ltd.
    Inventors: Hiroyuki Ebinuma, Kohei Takubo, Isamu Fukamachi, Saishu Yoshida, Hideaki Bujo, Chiaki Nakaseko, Yasushi Saito
  • Patent number: 8382376
    Abstract: A split-type sliding bearing for a crankshaft is formed of a pair of semi-cylindrical bearings halves which are fitted between a pair of housing halves having respectively high and low thermal expansion coefficients, one of the pair of bearing halves being supported on the housing half having a low thermal expansion coefficient, and the other of the pair of bearing halves being supported on the housing half having a high thermal expansion coefficient. The circumferential end zones of the bearing half supported on the housing half having a high thermal expansion coefficient have a thickness which is greater than that of the circumferential end zones of the bearing half supported on the housing half having a low thermal expansion coefficient.
    Type: Grant
    Filed: December 24, 2009
    Date of Patent: February 26, 2013
    Assignee: Daido Metal Company Ltd.
    Inventors: Aisuke Kuwabara, Osamu Ishigo, Yasushi Saito
  • Patent number: 8371754
    Abstract: A split-type sliding bearing for a crankshaft in an internal combustion engine is incorporated in a split-type bearing housing. The sliding bearing is formed of a first and a second semi-cylindrical bearing bodies combined to form a cylindrical body. The bearing housing has a cylindrical bearing retaining bore and is formed of a pair of housing halves. One of the housing halves has a lower stiffness, and the other has a higher stiffness. The first bearing body is held by the housing half having a lower stiffness. The second bearing body is held by the stiffer housing half. The first and second bearing bodies have equal outer diameters, and both of the circumferential end parts of the first bearing body have a larger thickness than those of the second bearing body prior to incorporation into the housing halves.
    Type: Grant
    Filed: December 24, 2009
    Date of Patent: February 12, 2013
    Assignee: Daido Metal Company Ltd.
    Inventors: Aisuke Kuwabara, Osamu Ishigo, Yasushi Saito
  • Patent number: 8367725
    Abstract: Provided are composition and/or methods useful in preventing onset and/or recurrence of cardiovascular events, especially in patients who have escaped the unstable period after cardiovascular angioplasty or in hyperlipidemia patients who have been treated with HMG-CoA RI.
    Type: Grant
    Filed: July 7, 2006
    Date of Patent: February 5, 2013
    Assignee: Mochida Pharmaceutical Co., Ltd.
    Inventors: Mitsuhiro Yokoyama, Hideki Origasa, Masunori Matsuzaki, Yuji Matsuzawa, Yasushi Saito, Yuichi Ishikawa, Shinichi Oikawa, Jun Sasaki, Hitoshi Hishida, Hiroshige Itakura, Toru Kita, Akira Kitabatake, Noriaki Nakaya, Toshiie Sakata, Kazuyuki Shimada, Kunio Shirato
  • Publication number: 20130029363
    Abstract: To provide a method and a diagnostic kit for determining the presence of a malignant tumor or the severity thereof, a method for selecting a therapeutic method therefor or evaluating the effect of the therapeutic method, or a method for estimating the risk of recurrence of the malignant tumor or determining the presence or absence of the recurrence. The method for determining the presence of a malignant tumor or the severity thereof, method for selecting a therapeutic method therefor or evaluating the effect of the therapeutic method, or method for estimating the risk of recurrence of the malignant tumor or the presence or absence of the recurrence is characterized by including 1) a step of measuring the concentration and/or quantity of soluble LR11 in a sample originating from a subject and 2) a step of comparing the value measured above with a measurement value of soluble LR11 obtained from a healthy subject group.
    Type: Application
    Filed: December 15, 2010
    Publication date: January 31, 2013
    Applicant: Sekisui Medical Co., Ltd.
    Inventors: Hiroyuki Ebinuma, Kohei Takubo, Masanao Matsuo, Isamu Fukamachi, Hideaki Bujo, Chiaki Nakaseko, Yasushi Saito
  • Publication number: 20120329852
    Abstract: Disclosed is a composition which is useful for preventing the occurrence of a cardiovascular event, particularly a composition which is expected to show a prophylactic effect on a cardiovascular event occurring in a hypercholesterolemia patient despite providing the patient with a treatment with HMG-CoA RI or a cardiovascular event occurring in a multiple risk patient.
    Type: Application
    Filed: September 5, 2012
    Publication date: December 27, 2012
    Inventors: Mitsuhiro YOKOYAMA, Hideki Origasa, Masunori Matsuzaki, Yuji Matsuzawa, Yasushi Saito
  • Patent number: 8328425
    Abstract: A split-type sliding bearing for a crankshaft in an internal combustion engine fits within a bearing housing having a housing half with a higher thermal expansion coefficient, and a housing half with a lower thermal expansion coefficient. The pair of semi-cylindrical bearings includes first and second semi-cylindrical bearings, the first being supported on the housing half having a higher thermal expansion coefficient, and the second being supported on the housing half having a lower thermal expansion coefficient. The first and second semi-cylindrical bearings have equal outer diameter, and the first has circumferential ends having a thickness smaller than that of the opposite circumferential ends of the second semi-cylindrical bearing.
    Type: Grant
    Filed: December 24, 2009
    Date of Patent: December 11, 2012
    Assignee: Daido Metal Company Ltd.
    Inventors: Tomohiro Ukai, Osamu Ishigo, Yasushi Saito
  • Publication number: 20120295976
    Abstract: By using a composition for preventing onset and/or recurrence of stroke which contains ethyl icosapentate as its effective component, onset and/or recurrence of stroke is prevented, or in particular, the onset and/or recurrence of stroke in a hyperlipidemia patient who has been treated with HMG-CoA RI, or in particular the recurrence of stroke in a patient who is beyond six months after the onset of stroke, is prevented.
    Type: Application
    Filed: July 26, 2012
    Publication date: November 22, 2012
    Inventors: Mitsuhiro Yokoyama, Hideki Origasa, Masunori Matsuzaki, Yuji Matsuzawa, Yasushi Saito
  • Patent number: 8315975
    Abstract: In one embodiment, the invention provides a method and apparatus for a wide area file system, including: creating a peer-to-peer wide-area file system that allows read and write sharing of data. In another embodiment, the invention provides a method and apparatus for a wide area file system, including using per-file replication to achieve high availability and performance in the wide-area distributed file system.
    Type: Grant
    Filed: December 9, 2002
    Date of Patent: November 20, 2012
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Yasushi Saito, Christos Karamanolis
  • Publication number: 20120287294
    Abstract: There is provided an image processing apparatus including an HDR (High Dynamic Range) processing unit inputting images picked up while exposure control that changes an exposure time is being carried out with a predetermined spatial period and a predetermined temporal period on pixels that compose an image sensor, and carrying out image processing. The HDR processing unit generates a first combined image by combining pixel values of a plurality of images with different sensitivities generated by an interpolation process using a plurality of consecutively picked-up images, generates a second combined image by combining pixel values of a plurality of images with different sensitivities generated by an interpolation process that uses a single picked-up image, and generates an HDR image by executing a pixel value blending process on the first combined image and the second combined image in accordance with a blending ratio calculated in accordance with movement detection information.
    Type: Application
    Filed: April 27, 2012
    Publication date: November 15, 2012
    Applicant: Sony Corporation
    Inventors: Shun Kaizu, Tomoo Mitsunaga, Yasushi Saito, Masanori Kasai
  • Patent number: 8311980
    Abstract: The invention is a system for and a method of maintaining namespace consistency in a wide-area file system. In one embodiment, a wide-area file system has a plurality of replicas for a file. Each replica of a file and parent directories for the file are at a node. An update to a replica of the file is propagated to other replicas of the file. In response to receiving a propagated update to a replica at a node, the replica for the file at the node is updated. A directory operation (e.g., rename, link or unlink) may affect a backpointer for a replica. When a backpointer for a replica at a node is not consistent with the parent directories for the replica at the node, the the parent directories are modified to be consistent with the backpointer. A modification may be performed at a node while an earlier inconsistent modification may be ignored. As a result, consistency is maintained among the replicas.
    Type: Grant
    Filed: December 1, 2003
    Date of Patent: November 13, 2012
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Yasushi Saito, Christos Karamanolis
  • Publication number: 20120257821
    Abstract: To provide an apparatus that generates an RGB pattern data from an image pickup signal by an image pickup element having an RGBW pattern and a method. An edge detection unit analyzes an output signal of the image pickup signal of the RGBW pattern to obtain edge information corresponding to the respective pixels, and a texture detection unit generates texture information. Furthermore, a parameter calculation unit executes an interpolation processing in which an applied pixel position is changed in accordance with an edge direction of a transform target pixel to generate parameters equivalent to an interpolation pixel value.
    Type: Application
    Filed: August 19, 2010
    Publication date: October 11, 2012
    Inventors: Yasushi Saito, Isao Hirota
  • Patent number: 8258183
    Abstract: By using a composition for preventing onset and/or recurrence of stroke which contains ethyl icosapentate as its effective component, onset and/or recurrence of stroke is prevented, or in particular, the onset and/or recurrence of stroke in a hyperlipidemia patient who has been treated with HMG-CoA RI, or in particular the recurrence of stroke in a patient who is beyond six months after the onset of stroke, is prevented.
    Type: Grant
    Filed: August 9, 2010
    Date of Patent: September 4, 2012
    Assignee: Mochida Pharmaceutical Co., Ltd.
    Inventors: Mitsuhiro Yokoyama, Hideki Origasa, Masunori Matsuzaki, Yuji Matsuzawa, Yasushi Saito
  • Patent number: 8251354
    Abstract: A gas spring includes a rod body that has a base end side movable into and out of a cylinder body. The rod body is urged in a direction outward of the cylinder body by pressure from a gas sealed inside the cylinder body. A cylindrical cover body includes a base end portion connected to a distal end portion of the rod body that projects outside of the cylinder body. An end portion of the cover body receives a head end portion of the cylinder body inside a cylindrical cover member at an end portion of the cylinder body. The cover member covers a portion of the spring that would otherwise be exposed to the air between the end portion of the cover body and the end portion of the cylinder body when the cylinder body is contracted inside the cover body.
    Type: Grant
    Filed: October 14, 2008
    Date of Patent: August 28, 2012
    Assignees: Kayaba Industry Co., Ltd, KYB-YS Co., Ltd.
    Inventors: Takashi Asa, Yasushi Saito
  • Patent number: 8170378
    Abstract: An image processing apparatus that generates an output image according to interpolation performed by using an input image includes a pixel-value calculating unit that calculates a pixel value of a pixel of the output image according to interpolation performed by using pixel values of pixels of the input image and an interpolation function, an edge determining unit that determines an edge direction, which is a direction of an edge in the pixel of the output image, using the input image, and an adjusting unit that adjusts the interpolation function such that a degree of pixels of the input image present in a direction along the edge direction contributing to the interpolation is large and a degree of pixels of the input image present in a direction orthogonal to the edge direction contributing to the interpolation is small.
    Type: Grant
    Filed: December 2, 2010
    Date of Patent: May 1, 2012
    Assignee: Sony Corporation
    Inventor: Yasushi Saito
  • Patent number: 8071085
    Abstract: The present invention relates to primary cultured adipocytes for gene therapy, where the adipocytes stably maintain a foreign gene encoding a protein that is secreted outside of cells. This invention provides cells suitable for gene therapy, which can replace bone marrow cells and liver cells used for conventional ex vivo gene therapy. The present invention established methods for transferring foreign genes into primary cultured adipocytes, which are suitable for ex vivo gene therapy; can be easily collected and implanted; and can be removed after implantation. Specifically, the present invention established these methods that use retroviral vectors. The present invention also established primary cultured adipocytes for gene therapy, where the adipocytes stably maintain a foreign gene encoding a protein that is secreted outside of cells.
    Type: Grant
    Filed: July 17, 2008
    Date of Patent: December 6, 2011
    Assignee: Eisai Co., Ltd.
    Inventors: Masashi Ito, Yasushi Saito
  • Patent number: 8055845
    Abstract: An embodiment of a method of cooperative caching for a distributed storage system begins with a step of requesting data from storage devices which hold the data. The method continues with a step of receiving any cached blocks and expected response times for providing non-cached blocks from the storage devices. The method concludes with a step of requesting a sufficient number of the non-cached blocks from one or more particular storage devices which provides an expectation of optimal performance.
    Type: Grant
    Filed: February 3, 2005
    Date of Patent: November 8, 2011
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Craig Soules, Arif Merchant, Alistair C. Veitch, Yasushi Saito, John Wilkes
  • Patent number: 8044753
    Abstract: A common-mode choke coil includes a core, external electrodes, a pair of wires, and a top plate. The core includes a winding core portion and a pair of flanges at both ends of the winding core portion. The upper surface of the winding core portion and the upper surfaces of the flanges are covered with a metal film. The external electrodes are provided on lower portions of the flanges. A pair of wires are wound on the winding core portion of the core, and the ends of the wires are connected to the external electrodes. The top plate is bonded to the upper surfaces of the flanges preferably via an adhesive.
    Type: Grant
    Filed: December 23, 2009
    Date of Patent: October 25, 2011
    Assignee: Murata Manufacturing Co., Ltd.
    Inventors: Takahiro Azuma, Tetsuya Morinaga, Takahiro Aoki, Yoshie Nishikawa, Shinya Hirai, Yoshimasa Goto, Yasushi Saito, Yu Ishiwata
  • Publication number: 20110243594
    Abstract: Upon recovery from a power-saving mode to a normal mode and then restart of fixing temperature control from a state in which the fixing temperature control is stopped, a control part (display control part 10 obtains a current temperature of a fixing part based on output of a temperature detector and required stabilization time T1 based on required stabilization time data, and based on necessary time data A and the number of remaining setting screens on which settings need to be made in a wizard format, issues a restart signal RS for restarting the fixing temperature control between a first time point TP1 reached by tracing back by the required stabilization time T1 from a predicted time point at which making the settings is predicted to complete and a second time point TP2 as a time point the necessary time before the first time point.
    Type: Application
    Filed: April 5, 2011
    Publication date: October 6, 2011
    Applicant: KYOCERA MITA CORPORATION
    Inventor: Yasushi SAITO
  • Publication number: 20110242603
    Abstract: A display input device 1 includes: a display part 11 displaying character string regions; an input part 12 accepting operation; a storage part 18 storing data including data for an image; and a display control part 10 controlling the display at the display part. The display control part 10 judges whether or not, of the character string regions, the adjacent character string regions include the same character string, and if they include the same character string, makes the display part highlight characters other than the same character string.
    Type: Application
    Filed: April 5, 2011
    Publication date: October 6, 2011
    Applicant: KYOCERA MITA CORPORATION
    Inventor: Yasushi SAITO