Abstract: A method and a kit for determining genome instability based on next generation sequencing (NGS) are disclosed. The new method is used to determine whether there is homologous recombination defect by calculating a comprehensive value of one or more of pathogenic germline and somatic mutations, such as SNV, indels, and CNVs, and Biallelic germline and somatic mutations, pathogenic mutational signature, copy number variation (CNV) in homologous recombination repair (HRR) gene, genomic structural variation and genome instability. The genomics DNA is interrupted and added with an A adapter; then corresponding polymerase chain reaction (PCR) is conducted, and Whole genome sequencing is performed; the hybrid capture is conducted with designed probes of HRR genes and SNPs, and a captured DNA library is subjected to amplification and library sequencing; and then professional bioinformatics software is used for evaluation to determine the homologous recombination deficiency (HRD) status.

Abstract: Methods are disclosed for determining the minimal residual cancer status of an individual utilizing assays that detect cancer associated genetic variation in extracellular DNA. The disclosed methods provide for personalized cancer detection based on the genetic profile of solid cancer tissue of an individual under study. The disclosed methods further provide for noise reduction in the sequencing of extracellular DNA and reduced false positive rates in minimal residual cancer status determination.

Abstract: Methods are disclosed for determining the minimal residual cancer status of an individual utilizing assays that detect cancer associated genetic variation in extracellular DNA. The disclosed methods provide for personalized cancer detection based on the genetic profile of solid cancer tissue of an individual under study. The disclosed methods further provide for noise reduction in the sequencing of extracellular DNA and reduced false positive rates in minimal residual cancer status determination.

Abstract: A method and a kit for determining genome instability based on next generation sequencing (NGS) are disclosed. The new method is used to determine whether there is homologous recombination defect by calculating a comprehensive value of one or more of pathogenic germline and somatic mutations, such as SNV, indels, and CNVs, and Biallelic germline and somatic mutations, pathogenic mutational signature, copy number variation (CNV) in homologous recombination repair (HRR) gene, genomic structural variation and genome instability. The genomics DNA is interrupted and added with an A adapter; then corresponding polymerase chain reaction (PCR) is conducted, and Whole genome sequencing is performed; the hybrid capture is conducted with designed probes of HRR genes and SNPs, and a captured DNA library is subjected to amplification and library sequencing; and then professional bioinformatics software is used for evaluation to determine the homologous recombination deficiency (HRD) status.

Abstract: The present disclosure relates to the technical field of industrial waste gas purification, in particular to a core-shell structured catalyst, a preparation method and use thereof. The present disclosure provides a core-shell structured catalyst including a metal oxide-molecular sieve as a core and porous silica (SiO2) as a shell, where the metal oxide-molecular sieve includes a molecular sieve and a metal oxide loaded on the molecular sieve, the metal oxide includes an oxide of a first metal and an oxide of a second metal, the first metal is Fe, Cu, Ti, Ni or Mn, and the second metal is Ce or La. The core-shell structured catalyst of the present disclosure can enable effective removal of HCN and AsH3 at the same time with a stable effect, and no secondary pollution.

Abstract: A system is provided for use with a video input signal and a video unit. The video input signal can be one of a two dimensional video signal and a three dimensional video signal. The video unit can display a three dimensional video and a two dimensional video. The system includes a receiver portion, a processing portion, a switching portion and an output portion. The receiver portion can receive the video input signal. The processing portion can output a first signal in a first mode of operation and can output a second signal in a second mode of operation, wherein the first signal is based on the video input signal and the second signal is based on the video input signal. The switching portion can switch the processing portion from the first mode of operation to the second mode of operation.

Abstract: A system is provided for use with a video input signal and a video unit. The video input signal can be one of a two dimensional video signal and a three dimensional video signal. The video unit can display a three dimensional video and a two dimensional video. The system includes a receiver portion, a processing portion, a switching portion and an output portion. The receiver portion can receive the video input signal. The processing portion can output a first signal in a first mode of operation and can output a second signal in a second mode of operation, wherein the first signal is based on the video input signal and the second signal is based on the video input signal. The switching portion can switch the processing portion from the first mode of operation to the second mode of operation.

Abstract: A system is provided for use with a video input signal and a video unit. The video input signal can be one of a two dimensional video signal and a three dimensional video signal. The video unit can display a three dimensional video and a two dimensional video. The system includes a receiver portion, a processing portion, a switching portion and an output portion. The receiver portion can receive the video input signal. The processing portion can output a first signal in a first mode of operation and can output a second signal in a second mode of operation, wherein the first signal is based on the video input signal and the second signal is based on the video input signal. The switching portion can switch the processing portion from the first mode of operation to the second mode of operation.

Abstract: A method of processing a sequence of coded video frames conveyed by a digital data stream, where each frame represents an image, includes receiving the sequence of coded video frames at a recording device, determining a frame interval between presentation of an ith coded frame of the sequence and an (i+1)th coded frame of the sequence, calculating a stream time stamp for the ith coded frame, and calculating a stream time stamp for the (i+1)th coded video frame based on the stream time stamp for the ith coded video frame and the previously determined frame interval.

Abstract: The present invention discloses a method for non-invasively detecting EGFR gene mutations in subjects, comprising the following steps: designing primers according to EGFR gene exons; extracting plasma DNAs in subjects; connecting the extracted plasma DNAs with tagging linkers; PCR pre-amplifying the tagging linkers connected plasma DNAs; cyclising the pre-amplified DNAs to obtain cyclised DNAs; PCR amplifying the cyclised DNAs using the designed primers; and high throughput sequencing the PCR amplified product and analyzing the EGFR gene mutations. The present invention also discloses a corresponding kit.

Abstract: A system is provided for use with a video input signal and a video unit. The video input signal can be one of a two dimensional video signal and a three dimensional video signal. The video unit can display a three dimensional video and a two dimensional video. The system includes a receiver portion, a processing portion, a switching portion and an output portion. The receiver portion can receive the video input signal. The processing portion can output a first signal in a first mode of operation and can output a second signal in a second mode of operation, wherein the first signal is based on the video input signal and the second signal is based on the video input signal. The switching portion can switch the processing portion from the first mode of operation to the second mode of operation.

Abstract: A client device, which can be a set-top box or a gateway device, can be operative to continue processing content (e.g., a television program) in its pipeline, while it is requesting a different content (e.g., tuning or obtaining a targeted ad). Instead of seeing a blank screen or a muted still-shot, the user in some circumstances would be able to continue to see a segment of the processed content information.

Abstract: A system is provided for use with a video input signal and a video unit. The video input signal can be one of a two dimensional video signal and a three dimensional video signal. The video unit can display a three dimensional video and a two dimensional video. The system includes a receiver portion, a processing portion, a switching portion and an output portion. The receiver portion can receive the video input signal. The processing portion can output a first signal in a first mode of operation and can output a second signal in a second mode of operation, wherein the first signal is based on the video input signal and the second signal is based on the video input signal. The switching portion can switch the processing portion from the first mode of operation to the second mode of operation.

Abstract: A system is provided for use with a video input signal and a video unit. The video input signal can be one of a two dimensional video signal and a three dimensional video signal. The video unit can display a three dimensional video and a two dimensional video. The system includes a receiver portion, a processing portion, a switching portion and an output portion. The receiver portion can receive the video input signal. The processing portion can output a first signal in a first mode of operation and can output a second signal in a second mode of operation, wherein the first signal is based on the video input signal and the second signal is based on the video input signal. The switching portion can switch the processing portion from the first mode of operation to the second mode of operation.

Abstract: A client device, which can be a set-top box or a gateway device, can be operative to continue processing content (e.g., a television program) in its pipeline, while it is requesting a different content (e.g., tuning or obtaining a targeted ad). Instead of seeing a blank screen or a muted still-shot, the user in some circumstances would be able to continue to see a segment of the processed content information.

Abstract: The present invention discloses a method for non-invasively detecting EGFR gene mutations in subjects, comprising the following steps: designing primers according to EGFR gene exons; extracting plasma DNAs in subjects; connecting the extracted plasma DNAs with tagging linkers; PCR pre-amplifying the tagging linkers connected plasma DNAs; cyclising the pre-amplified DNAs to obtain cyclised DNAs; PCR amplifying the cyclised DNAs using the designed primers; and high throughput sequencing the PCR amplified product and analyzing the EGFR gene mutations. The present invention also discloses a corresponding kit.

Abstract: A system is provided for use with a video input signal and a video unit. The video input signal can be one of a two dimensional video signal and a three dimensional video signal. The video unit can display a three dimensional video and a two dimensional video. The system includes a receiver portion, a processing portion, a switching portion and an output portion. The receiver portion can receive the video input signal. The processing portion can output a first signal in a first mode of operation and can output a second signal in a second mode of operation, wherein the first signal is based on the video input signal and the second signal is based on the video input signal. The switching portion can switch the processing portion from the first mode of operation to the second mode of operation.

Abstract: A method and system that configures an HDMI source device to use initial output parameters for communicating with an HDMI sink device, detects an abnormal operation performed by the HDMI sink device, selects a test of the HDMI sink device, applies the test, evaluates a result to determine whether the test produces a desired result, and modifies the initial output parameters to create revised output parameters. When the test produces the desired result, the revised output parameters will enable the HDMI sink device to produce the desired result. When the test fails to produce the desired result, the revised output parameters are conservative parameters that fail to produce the abnormal operation. The method reconfigures the HDMI source device to use the revised output parameters for communicating with the HDMI sink device, and saves the revised output parameters.

Abstract: A system is provided for use with a video input signal and a video unit. The video input signal can be one of a two dimensional video signal and a three dimensional video signal. The video unit can display a three dimensional video and a two dimensional video. The system includes a receiver portion, a processing portion, a switching portion and an output portion. The receiver portion can receive the video input signal. The processing portion can output a first signal in a first mode of operation and can output a second signal in a second mode of operation, wherein the first signal is based on the video input signal and the second signal is based on the video input signal. The switching portion can switch the processing portion from the first mode of operation to the second mode of operation.

Abstract: A method of modifying a digital data stream composed of a sequence of frames, where each frame represents an image and includes a data field specifying a presentation time stamp value for the frame. If there is a discontinuity in presentation time stamp value between a next frame and a first frame, a value representing a stream time stamp of interest is assigned to a variable for representing the value of the stream time stamp of interest at a point of discontinuity in presentation time stamp, and a value of the presentation time stamp is assigned to a variable for representing the first frame's clock time based on presentation time stamp, and the next frame is stored in a database using as an index the value representing a stream time stamp of interest.