Patents by Inventor Yefim Brun

Yefim Brun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190185893
    Abstract: Compositions are disclosed herein comprising a graft copolymer that comprises: (i) a backbone comprising dextran that has been modified with about 1%-25% alpha-1,2 branches, and (ii) one or more alpha-1,3-glucan side chains comprising at least about 50% alpha-1,3 glycosidic linkages. Further disclosed are reactions for producing such graft copolymers, as well as their use in derivatives, films and various other applications.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 20, 2019
    Inventors: RONG GUAN, JAMES JOSHUA OHANE, NIKITA ILTCHENKO, YEFIM BRUN, BRIAN MCCAULEY, LAURIE A. HOWE, YOUGEN LI
  • Patent number: 10308968
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: June 4, 2019
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Mark S. Payne, Yefim Brun, Hongxian He, Thomas Scholz
  • Publication number: 20190112585
    Abstract: Reactions comprising water, sucrose, and one or more glucosyltransferase enzymes are disclosed herein. Glucosyltransferase enzymes used in these reactions comprise certain motifs allowing production of insoluble poly alpha-1,3-glucan having at least 95% alpha-1,3 glycosidic linkages.
    Type: Application
    Filed: November 14, 2018
    Publication date: April 18, 2019
    Inventors: Mark S. Payne, Yefim Brun, Richard R. Bott
  • Patent number: 10260053
    Abstract: Compositions are disclosed herein comprising poly alpha-1,3-1,6-glucan with a weight average degree of polymerization (DPw) of at least 1000. This glucan polymer comprises at least 30% alpha-1,3 linkages and at least 30% alpha-1,6 linkages. Further disclosed are glucosyltransferase enzymes that synthesize poly alpha-1,3-1,6-glucan. Ether derivatives of poly alpha-1,3-1,6-glucan and methods of using such derivatives as viscosity modifiers are also disclosed.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: April 16, 2019
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Jayme L. Paullin, Mark S. Payne, T. Joseph Dennes, Yefim Brun, Rakesh Nambiar, Thomas H Scholz
  • Publication number: 20190040432
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Application
    Filed: October 18, 2018
    Publication date: February 7, 2019
    Applicant: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: MARK S. PAYNE, YEFIM BRUN, HONGXIAN HE, THOMAS SCHOLZ
  • Publication number: 20180355072
    Abstract: Compositions are disclosed herein comprising dextran that comprises (i) 87-93 wt % glucose linked at positions 1 and 6; (ii) 0.1-1.2 wt % glucose linked at positions 1 and 3; (iii) 0.1-0.7 wt % glucose linked at positions 1 and 4; (iv) 7.7-8.6 wt % glucose linked at positions 1, 3 and 6; and (v) about 0.4-1.7 wt % glucose linked at (a) positions 1, 2 and 6, or (b) positions 1, 4 and 6. Aqueous forms of this composition have enhanced viscosity profiles. Further disclosed are methods of using compositions comprising dextran, such as increasing the viscosity of an aqueous composition. Enzymatic reactions for producing dextran are also disclosed.
    Type: Application
    Filed: August 24, 2018
    Publication date: December 13, 2018
    Inventors: RAKESH NAMBIAR, RONG GUAN, QIONG CHENG, ROBERT DICOSIMO, JAYME L. PAULLIN, YUANFENG LIANG, CHARLES R. POWLEY, YEFIM BRUN
  • Patent number: 10150862
    Abstract: Transesterified-blend compositions comprising transesterified furan-based polyester and transesterified terephthalate-based polyester disclosed herein and articles made therefrom.
    Type: Grant
    Filed: May 1, 2015
    Date of Patent: December 11, 2018
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Yefim Brun, Alicia Maria Castagna, Ken-Hsuan Liao, Fredrik Nederberg, Elizabeth Forrester McCord, Christopher John Rasmussen
  • Publication number: 20180340199
    Abstract: A method for producing insoluble alpha-1,3-glucan is disclosed. Embodiments of the method comprise providing (i) oligosaccharides that comprise alpha-1,3 and alpha-1,6 glycosidic linkages, or (ii) oligosaccharides derived from a glucosyltransferase reaction; and contacting at least water, sucrose, a glucosyltransferase enzyme, and the oligosaccharides provided in the first step. Glucosyltransferase reaction compositions embodying such a method, and insoluble products thereof, are also disclosed. Yield and other product benefits can be realized when practicing the disclosed subject matter.
    Type: Application
    Filed: May 22, 2018
    Publication date: November 29, 2018
    Inventors: Kevin D. Nagy, Susan Marie Hennessey, Yefim Brun, Michael Reichman
  • Publication number: 20180305672
    Abstract: Glucosyltransferase enzymes are disclosed herein that produce branched alpha-glucan polymer. Also disclosed, for example, are polynucleotides encoding these enzymes, as well as methods of producing branched alpha-glucan polymer.
    Type: Application
    Filed: April 18, 2018
    Publication date: October 25, 2018
    Inventors: MARK S. PAYNE, YEFIM BRUN, RICHARD R. BOTT
  • Publication number: 20180282918
    Abstract: Nonwoven webs comprising a water insoluble ?-(1,3?glucan) polymer and methods of forming the nonwoven webs are disclosed. The water insoluble ?-(1,3?glucan) polymer comprises 90% or greater ?-1,3-glycosidic linkages, less than 1% by weight of ?-1,3,6-glycosidic branch points, a number average degree of polymerization in the range of from 55 to 10,000, and a ratio of apparent DPw to true DPw in the range of from 2 to 10. The nonwoven webs can be used for personal hygiene wipes, filtration media, apparel, or other uses.
    Type: Application
    Filed: November 8, 2016
    Publication date: October 4, 2018
    Inventors: Natnael Behabtu, Joseph F. Roeske, Yefim Brun
  • Publication number: 20180273919
    Abstract: Compositions are disclosed herein comprising poly alpha-1,3-1,6-glucan with a weight average degree of polymerization (DPw) of at least 1000. This glucan polymer comprises at least 30% alpha-1,3 linkages and at least 30% alpha-1,6 linkages. Further disclosed are glucosyltransferase enzymes that synthesize poly alpha-1,3-1,6-glucan. Ether derivatives of poly alpha-1,3-1,6-glucan and methods of using such derivatives as viscosity modifiers are also disclosed.
    Type: Application
    Filed: March 23, 2018
    Publication date: September 27, 2018
    Inventors: JAYME L PAULLIN, MARK S. PAYNE, T. JOSEPH DENNES, YEFIM BRUN, RAKESH NAMBIAR, THOMAS H SCHOLZ
  • Patent number: 10059779
    Abstract: Compositions are disclosed herein comprising dextran that comprises (i) 87-93 wt % glucose linked at positions 1 and 6; (ii) 0.1-1.2 wt % glucose linked at positions 1 and 3; (iii) 0.1-0.7 wt % glucose linked at positions 1 and 4; (iv) 7.7-8.6 wt % glucose linked at positions 1, 3 and 6; and (v) about 0.4-1.7 wt % glucose linked at (a) positions 1, 2 and 6, or (b) positions 1, 4 and 6. Aqueous forms of this composition have enhanced viscosity profiles. Further disclosed are methods of using compositions comprising dextran, such as increasing the viscosity of an aqueous composition. Enzymatic reactions for producing dextran are also disclosed.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: August 28, 2018
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Rakesh Nambiar, Rong Guan, Qiong Cheng, Robert Dicosimo, Jayme L Paullin, Yuanfeng Liang, Charles R Powley, Yefim Brun
  • Patent number: 9988610
    Abstract: Glucosyltransferase enzymes are disclosed herein that produce branched alpha-glucan polymer. Also disclosed, for example, are polynucleotides encoding these enzymes, as well as methods of producing branched alpha-glucan polymer.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: June 5, 2018
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Mark S Payne, Yefim Brun, Richard R Bott
  • Patent number: 9926541
    Abstract: Compositions are disclosed herein comprising poly alpha-1,3-1,6-glucan with a weight average degree of polymerization (DPw) of at least 1000. This glucan polymer comprises at least 30% alpha-1,3 linkages and at least 30% alpha-1,6 linkages. Further disclosed are glucosyltransferase enzymes that synthesize poly alpha-1,3-1,6-glucan. Ether derivatives of poly alpha-1,3-1,6-glucan and methods of using such derivatives as viscosity modifiers are also disclosed.
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: March 27, 2018
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Jayme L Paullin, Mark S Payne, T Joseph Dennes, Yefim Brun, Rakesh Nambiar, Thomas Scholz
  • Publication number: 20170058119
    Abstract: Transesterified-blend compositions comprising transesterified furan-based polyester and transesterified terephthalate-based polyester disclosed herein and articles made therefrom.
    Type: Application
    Filed: May 1, 2015
    Publication date: March 2, 2017
    Inventors: Yefim Brun, Alicia Maria Castagna, Ken-Hsuan Liao, Fredrik Nederberg, Elizabeth Forrester McCord, Christopher John Rasmussen
  • Publication number: 20170002335
    Abstract: Reactions comprising water, sucrose, and one or more glucosyltransferase enzymes are disclosed herein. Glucosyltransferase enzymes used in these reactions comprise certain motifs allowing production of insoluble poly alpha-1,3-glucan having at least 95% alpha-1,3 glycosidic linkages.
    Type: Application
    Filed: June 15, 2016
    Publication date: January 5, 2017
    Inventors: MARK S PAYNE, Yefim Brun, Richard R Bott
  • Publication number: 20170002336
    Abstract: Glucosyltransferase enzymes are disclosed herein that produce branched alpha-glucan polymer. Also disclosed, for example, are polynucleotides encoding these enzymes, as well as methods of producing branched alpha-glucan polymer.
    Type: Application
    Filed: June 15, 2016
    Publication date: January 5, 2017
    Inventors: MARK S. PAYNE, YEFIM BRUN, RICHARD R. BOTT
  • Publication number: 20160273012
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Application
    Filed: March 25, 2016
    Publication date: September 22, 2016
    Inventors: MARK S. PAYNE, Yefim Brun, Hongxian He, Thomas Scholz
  • Publication number: 20160122445
    Abstract: Compositions are disclosed herein comprising dextran that comprises (i) 87-93 wt % glucose linked at positions 1 and 6; (ii) 0.1-1.2 wt % glucose linked at positions 1 and 3; (iii) 0.1-0.7 wt % glucose linked at positions 1 and 4; (iv) 7.7-8.6 wt % glucose linked at positions 1, 3 and 6; and (v) about 0.4-1.7 wt % glucose linked at (a) positions 1, 2 and 6, or (b) positions 1, 4 and 6. Aqueous forms of this composition have enhanced viscosity profiles. Further disclosed are methods of using compositions comprising dextran, such as increasing the viscosity of an aqueous composition. Enzymatic reactions for producing dextran are also disclosed.
    Type: Application
    Filed: November 5, 2015
    Publication date: May 5, 2016
    Inventors: RAKESH NAMBIAR, Rong Guan, Qiong Cheng, Robert Dicosimo, Jayme L. Paullin, Yuanfeng Liang, Charles R. Powley, Yefim Brun
  • Patent number: 9296997
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: March 29, 2016
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Mark S Payne, Yefim Brun, Hongxian He, Thomas Scholz