Patents by Inventor Yefim Brun

Yefim Brun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170002336
    Abstract: Glucosyltransferase enzymes are disclosed herein that produce branched alpha-glucan polymer. Also disclosed, for example, are polynucleotides encoding these enzymes, as well as methods of producing branched alpha-glucan polymer.
    Type: Application
    Filed: June 15, 2016
    Publication date: January 5, 2017
    Inventors: MARK S. PAYNE, YEFIM BRUN, RICHARD R. BOTT
  • Publication number: 20160273012
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Application
    Filed: March 25, 2016
    Publication date: September 22, 2016
    Inventors: MARK S. PAYNE, Yefim Brun, Hongxian He, Thomas Scholz
  • Publication number: 20160122445
    Abstract: Compositions are disclosed herein comprising dextran that comprises (i) 87-93 wt % glucose linked at positions 1 and 6; (ii) 0.1-1.2 wt % glucose linked at positions 1 and 3; (iii) 0.1-0.7 wt % glucose linked at positions 1 and 4; (iv) 7.7-8.6 wt % glucose linked at positions 1, 3 and 6; and (v) about 0.4-1.7 wt % glucose linked at (a) positions 1, 2 and 6, or (b) positions 1, 4 and 6. Aqueous forms of this composition have enhanced viscosity profiles. Further disclosed are methods of using compositions comprising dextran, such as increasing the viscosity of an aqueous composition. Enzymatic reactions for producing dextran are also disclosed.
    Type: Application
    Filed: November 5, 2015
    Publication date: May 5, 2016
    Inventors: RAKESH NAMBIAR, Rong Guan, Qiong Cheng, Robert Dicosimo, Jayme L. Paullin, Yuanfeng Liang, Charles R. Powley, Yefim Brun
  • Patent number: 9296997
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: March 29, 2016
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Mark S Payne, Yefim Brun, Hongxian He, Thomas Scholz
  • Patent number: 9296996
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: March 29, 2016
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Mark S Payne, Yefim Brun, Hongxian He, Thomas Scholz
  • Patent number: 9284539
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: March 15, 2016
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Mark S Payne, Yefim Brun, Hongxian He, Thomas Scholz
  • Patent number: 9284540
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: March 15, 2016
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Mark S. Payne, Yefim Brun, Hongxian He, Thomas Scholz
  • Patent number: 9260701
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: February 16, 2016
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Mark S Payne, Yefim Brun, Hongxian He, Thomas Scholz
  • Patent number: 9260702
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: February 16, 2016
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Mark S Payne, Yefim Brun, Hongxian He, Thomas Scholz
  • Patent number: 9228177
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: January 5, 2016
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Mark S Payne, Yefim Brun, Hongxian He, Thomas Scholz
  • Patent number: 9228176
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: January 5, 2016
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Mark S Payne, Yefim Brun, Hongxian He, Thomas Scholz
  • Publication number: 20150232819
    Abstract: Compositions are disclosed herein comprising poly alpha-1,3-1,6-glucan with a weight average degree of polymerization (DPw) of at least 1000. This glucan polymer comprises at least 30% alpha-1,3 linkages and at least 30% alpha-1,6 linkages. Further disclosed are glucosyltransferase enzymes that synthesize poly alpha-1,3-1,6-glucan. Ether derivatives of poly alpha-1,3-1,6-glucan and methods of using such derivatives as viscosity modifiers are also disclosed.
    Type: Application
    Filed: February 11, 2015
    Publication date: August 20, 2015
    Inventors: JAYME L. PAULLIN, Mark S. Payne, T. Joseph Dennes, Yefim Brun, Rakesh Nambiar, Thomas Scholz
  • Publication number: 20150232785
    Abstract: Compositions are disclosed herein comprising poly alpha-1,3-1,6-glucan with a weight average degree of polymerization (DPw) of at least 1000. This glucan polymer comprises at least 30% alpha-1,3 linkages and at least 30% alpha-1,6 linkages. Further disclosed are glucosyltransferase enzymes that synthesize poly alpha-1,3-1,6-glucan. Ether derivatives of poly alpha-1,3-1,6-glucan and methods of using such derivatives as viscosity modifiers are also disclosed.
    Type: Application
    Filed: February 11, 2015
    Publication date: August 20, 2015
    Inventors: JAYME L. PAULLIN, Mark S. Payne, T. Joseph Dennes, Yefim Brun, Rakesh Nambiar, Thomas Scholz
  • Publication number: 20150010956
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Application
    Filed: September 19, 2014
    Publication date: January 8, 2015
    Inventors: MARK S. PAYNE, Yefim Brun, Hongxian He, Thomas Scholz
  • Publication number: 20150010955
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Application
    Filed: September 19, 2014
    Publication date: January 8, 2015
    Inventors: MARK S. PAYNE, YEFIM BRUN, HONGXIAN HE, THOMAS SCHOLZ
  • Publication number: 20150010954
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Application
    Filed: September 19, 2014
    Publication date: January 8, 2015
    Inventors: MARK S. PAYNE, Yefim Brun, Hongxian He, Thomas Scholz
  • Publication number: 20150004651
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Application
    Filed: September 19, 2014
    Publication date: January 1, 2015
    Inventors: MARK S PAYNE, Yefim Brun, Hongxian He, Thomas Scholz
  • Publication number: 20150004653
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Application
    Filed: September 19, 2014
    Publication date: January 1, 2015
    Inventors: MARK S. PAYNE, Yefim Brun, Hongxian He, Thomas Scholz
  • Publication number: 20150004650
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Application
    Filed: September 19, 2014
    Publication date: January 1, 2015
    Inventors: MARK S. PAYNE, Yefim Brun, Hongxian He, Thomas Scholz
  • Publication number: 20150004649
    Abstract: Reaction solutions are disclosed herein comprising water, sucrose and a glucosyltransferase enzyme that synthesizes poly alpha-1,3-glucan. The glucosyltransferase enzyme can synthesize insoluble glucan polymer having at least 50% alpha-1,3 glycosidic linkages and a number average degree of polymerization of at least 100. Further disclosed are methods of using such glucosyltransferase enzymes to produce insoluble poly alpha-1,3-glucan.
    Type: Application
    Filed: September 19, 2014
    Publication date: January 1, 2015
    Inventors: MARK S. PAYNE, Yefim Brun, Hongxian He, Thomas Scholz