Abstract: A method of finishing edges of glass sheets may include engaging an edge of a glass sheet with a groove of an edge finishing wheel as the edge finishing wheel is rotated with a motor. A working current of the motor may be monitored when the edge finishing wheel is engaged with the edge of the glass sheet. The working current may be indicative of a working torque of the motor. The method may further include determining if the working torque of the motor is greater than an upper threshold torque value corresponding to a maximum groove depth. A blade of a cutting head is engaged with an outer diameter of the edge finishing wheel when the working torque of the motor is greater than the upper threshold torque value thereby shaving material from the outer diameter of the edge finishing wheel and decreasing the working torque of the motor.

Abstract: A glass or glass-ceramic carrier substrate, the substrate having undergone at least one complete cycle of a semiconductor fabrication process and having also undergone a reclamation process following the end of the semiconductor fabrication process; the glass or glass-ceramic carrier substrate comprising at least one of the following properties: (i) a coefficient of thermal expansion of less than 13 ppm/° C.; (ii) a Young's Modulus of 70 GPa to 150 GPa; (iii) an IR transmission of greater than 80% at a wavelength of 1064 nm; (iv) a UV transmission of greater than 20% at a wavelength of 255 nm to 360 nm; (v) a thickness tolerance within the same range as the thickness tolerance of the carrier substrate before undergoing at least one complete cycle of the semiconductor fabrication process; (vi) a total thickness variation of less than 2.5 ?m; (vii) a failure strength of greater than 80 MPa using a 4-point-bending test; (viii) a pre-shape of 50 ?m to 300 ?m.

Abstract: A glass or glass-ceramic carrier substrate, the substrate having undergone at least one complete cycle of a semiconductor fabrication process and having also undergone a reclamation process following the end of the semiconductor fabrication process; the glass or glass-ceramic carrier substrate comprising at least one of the following properties: (i) a coefficient of thermal expansion of less than 13 ppm/° C.; (ii) a Young's Modulus of 70 GPa to 150 GPa; (iii) an IR transmission of greater than 80% at a wavelength of 1064 nm; (iv) a UV transmission of greater than 20% at a wavelength of 255 nm to 360 nm; (v) a thickness tolerance within the same range as the thickness tolerance of the carrier substrate before undergoing at least one complete cycle of the semiconductor fabrication process; (vi) a total thickness variation of less than 2.5 ?m; (vii) a failure strength of greater than 80 MPa using a 4-point-bending test; (viii) a pre-shape of 50 ?m to 300 ?m.

Abstract: The disclosure relates to methods for nucleic acid purification, comprising (a) combining a sample comprising at least one nucleic acid with a binding buffer comprising at least one magnetic particle and having a pH ranging from about 4 to about 10 to form a solution; (b) incubating the sample with the binding buffer for a time period sufficient to reversibly bind the at least one nucleic acid to the at least one magnetic particle to form at least one modified magnetic particle, (c) separating the at least one modified magnetic particle from the solution, (d) washing the at least one modified magnetic particle with at least one wash buffer; and (e) combining the at least one modified magnetic particle with an elution buffer Kits comprising these buffers and magnetic particles are also disclosed herein.

Abstract: Articles with at least one finished edge and methods and systems for forming the same are disclosed. A method of forming a glass article having at least one finished edge includes heating a substrate to a preparation temperature, the substrate having at least one unfinished edge, applying a laser to the at least one unfinished edge of the substrate, the laser causing a temperature of the at least one unfinished edge to increase from the preparation temperature to a finishing temperature, and reducing a power of the laser over a time period of at least about 10 seconds until the laser is deactivated, resulting in the glass article comprising the at least one finished edge.

Abstract: The disclosure relates to methods for nucleic acid purification, comprising (a) combining a sample comprising at least one nucleic acid with a binding buffer comprising at least one magnetic particle and having a pH ranging from about 4 to about 10 to form a solution; (b) incubating the sample with the binding buffer for a time period sufficient to reversibly bind the at least one nucleic acid to the at least one magnetic particle to form at least one modified magnetic particle, (c) separating the at least one modified magnetic particle from the solution, (d) washing the at least one modified magnetic particle with at least one wash buffer; and (e) combining the at least one modified magnetic particle with an elution buffer Kits comprising these buffers and magnetic particles are also disclosed herein.

Abstract: The disclosure relates to methods for nucleic acid purification, comprising (a) combining a sample comprising at least one nucleic acid with a binding buffer comprising at least one magnetic particle and having a pH ranging from about 4 to about 10 to form a solution; (b) incubating the sample with the binding buffer for a time period sufficient to reversibly bind the at least one nucleic acid to the at least one magnetic particle to form at least one modified magnetic particle, (c) separating the at least one modified magnetic particle from the solution, (d) washing the at least one modified magnetic particle with at least one wash buffer; and (e) combining the at least one modified magnetic particle with an elution buffer Kits comprising these buffers and magnetic particles are also disclosed herein.

Abstract: Provided herein are systems, kits, and methods for nucleic acid purification from blood samples. In particular, provided herein are reagents, e.g. dissolving buffer comprising sarcosine, and methods of using such reagents, for high yield purification of nucleic acids from blood samples, including dried blood samples. Also claimed is a system for purifying nucleic acids from whole blood samples comprising a lysis buffer comprising guanidine and disodium hydrogen phosphate. Magnetic particles are suggested as solid support for capturing the nucleic acids.

Abstract: The disclosure relates to methods for nucleic acid purification, comprising (a) combining a sample comprising at least one nucleic acid with a suspension buffer to form a suspension, (b) combining the suspension with a lysis buffer to form a lysate, (c) combining the lysate with a binding buffer to form a solution; (d) combining the solution with at least one magnetic particle to form a combined solution comprising at least one modified magnetic particle reversibly bound to the at least one nucleic acid, (e) separating the at least one modified magnetic particle from the combined solution, (f) washing the at least one modified magnetic particle with a first wash buffer and a second wash buffer, and (g) combining the at least one modified magnetic particle with an elution buffer. Kits comprising these buffers and magnetic particles are also disclosed herein.

Abstract: The disclosure relates to methods for nucleic acid purification, comprising (a) combining a sample comprising at least one nucleic acid with a binding buffer comprising at least one magnetic particle and having a pH ranging from about 4 to about 10 to form a solution; (b) incubating the sample with the binding buffer for a time period sufficient to reversibly bind the at least one nucleic acid to the at least one magnetic particle to form at least one modified magnetic particle, (c) separating the at least one modified magnetic particle from the solution, (d) washing the at least one modified magnetic particle with at least one wash buffer; and (e) combining the at least one modified magnetic particle with an elution buffer Kits comprising these buffers and magnetic particles are also disclosed herein.

Abstract: A level shifter includes a signal receiving module, including at least one signal receiving end for receiving at least one input signal and being conducted or non-conducted according to the input signal; a level adjusting module, configured to generate the adjusted output signal according to the input signal, wherein the level adjusting module includes a first connection end and a second connection end, the second connection end is coupled to the signal receiving module; and a switch module, including a first end coupling to the first connection end and a second end coupling to the second connection end. If the switch module is conducted, an current path is formed between the first connection end, the second connection end and the signal receiving module through the switch module. If the switch module is not conducted, current is blocked from flowing from the first connection end to the second connection end.

Abstract: A level shifter includes a signal receiving module, including at least one signal receiving end for receiving at least one input signal and being conducted or non-conducted according to the input signal; a level adjusting module, configured to generate the adjusted output signal according to the input signal, wherein the level adjusting module includes a first connection end and a second connection end, the second connection end is coupled to the signal receiving module; and a switch module, including a first end coupling to the first connection end and a second end coupling to the second connection end. If the switch module is conducted, an current path is formed between the first connection end, the second connection end and the signal receiving module through the switch module. If the switch module is not conducted, current is blocked from flowing from the first connection end to the second connection end.

Abstract: A charging/discharging circuit includes a connection terminal, a reference current providing module, an up current module and a down current module. The down current module includes: a first switch module, having a first control terminal, for receiving the down signal to determine whether the first switch module is turned on; a first bias transistor, having a first terminal coupled to the connection terminal, a second terminal coupled to the first switch module, and a control terminal coupled to the reference current providing module; and a first capacitor simulation transistor, having a first terminal and a second terminal coupled to the control terminal of the first switch module, and a control terminal coupled to the control terminal of the first bias transistor.

Abstract: A microfluidic cell culture apparatus includes a cell retention chamber and a perfusion channel. The cell retention chamber has a structured surface. The structured surface includes a major surface from which a plurality of projections extends into the chamber. The plurality of projections are arranged to suspend cells cultured in the chamber above the major surface. The first perfusion channel is configured to provide laminar flow of a fluid through the channel and forms a plurality of openings in communication with the cell retention chamber. The openings are configured to prevent cells from the retention chamber from entering the perfusion channel.

Abstract: A touch sensing method and associated circuit are provided. In one aspect, a touch control circuit includes a first current source, a second current source, a plurality of switches, a hysteresis comparator, a frequency divider and a flip-flop. The switches are couple to a plurality of external contact points. The hysteresis comparator is coupled to a first reference comparison voltage and a second reference comparison voltage. Each of the external contact points is selectively coupled to an input terminal of the hysteresis comparator through the switches. The first current source and the second current source are coupled to the input terminal of the hysteresis comparator to generate a sensing voltage. The hysteresis comparator compares the sensing voltage with the first reference comparison voltage and the second reference comparison voltage to generate a hysteresis comparison output to control the first current source or the second current source.

Abstract: A microfluidic cell culture apparatus includes a cell retention chamber and a perfusion channel. The cell retention chamber has a structured surface. The structured surface includes a major surface from which a plurality of projections extends into the chamber. The plurality of projections are arranged to suspend cells cultured in the chamber above the major surface. The first perfusion channel is configured to provide laminar flow of a fluid through the channel and forms a plurality of openings in communication with the cell retention chamber. The openings are configured to prevent cells from the retention chamber from entering the perfusion channel.

Abstract: An envelope detecting method performing squelch detection on a pair of differential signal includes: by a voltage divider, providing a real-time reference signal according to a sum of the pair of differential signals; and comparing two comparison signals associated with the real-time reference signals and the pair of differential signals to generate a squelch detection signal.

Abstract: A microfluidic cell culture apparatus includes a cell retention chamber and a perfusion channel. The cell retention chamber has a structured surface. The structured surface includes a major surface from which a plurality of projections extends into the chamber. The plurality of projections are arranged to suspend cells cultured in the chamber above the major surface. The first perfusion channel is configured to provide laminar flow of a fluid through the channel and forms a plurality of openings in communication with the cell retention chamber. The openings are configured to prevent cells from the retention chamber from entering the perfusion channel.

Abstract: A digital apparatus includes a timing control circuit, a period counter, a phase digitizer and a calculation circuit. The timing control circuit generates a first control signal according to a square wave signal and a predetermined value. The period counter generates a first digital value according to a reference clock signal and the first control signal. The phase digitizer generates a second digital value according to a phase difference between the square wave signal and the reference clock signal. The calculation circuit generates an output digital value according to the first digital value and the second digital value. An object of obtaining a high-resolution digitization with a reasonable sampling clock is realized by effectively combining the period counter with the phase digitizer.

Abstract: An envelope detecting method performing squelch detection on a pair of differential signal includes: by a voltage divider, providing a real-time reference signal according to a sum of the pair of differential signals; and comparing two comparison signals associated with the real-time reference signals and the pair of differential signals to generate a squelch detection signal.