Patents by Inventor Yi-Chun Huang

Yi-Chun Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIKV RNA VACCINES
    Publication number: 20200368344
    Abstract: Aspects of the disclosure relate to nucleic acid vaccines. The vaccines include one or more RNA polynucleotides having an open reading frame encoding one or more Chikungunya antigen(s), one or more Zika virus antigens, and one or more Dengue antigens. Methods for preparing and using such vaccines are also described.
    Type: Application
    Filed: June 10, 2020
    Publication date: November 26, 2020
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Eric Yi-Chun Huang, Kapil Bahl, Tal Zaks, Sunny Himansu, Sayda Mahgoub Elbashir
  • ZIKA VIRUS MRNA VACCINES
    Publication number: 20200368343
    Abstract: Aspects of the disclosure relate to nucleic acid vaccines. The vaccines include one or more RNA polynucleotides having an open reading frame encoding one or more Chikungunya antigen(s), one or more Zika virus antigens, and one or more Dengue antigens. Methods for preparing and using such vaccines are also described.
    Type: Application
    Filed: June 10, 2020
    Publication date: November 26, 2020
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Eric Yi-Chun Huang, Kapil Bahl, Tal Zaks, Sunny Himansu
  • ZIKA VIRUS RNA VACCINES
    Publication number: 20200289638
    Abstract: The disclosure relates to tropical diseases such as viral mosquito borne illnesses and the treatment thereof. The invention includes ribonucleic acid vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines for treating and preventing tropical disease.
    Type: Application
    Filed: April 16, 2020
    Publication date: September 17, 2020
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu, Eric Yi-Chun Huang, Tal Zaks
  • CHIKUNGUNYA VIRUS RNA VACCINES
    Publication number: 20200289639
    Abstract: The disclosure relates to tropical diseases such as viral mosquito borne illnesses and the treatment thereof. The invention includes ribonucleic acid vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines for treating and preventing tropical disease.
    Type: Application
    Filed: April 21, 2020
    Publication date: September 17, 2020
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu, Eric Yi-Chun Huang, Tal Zaks, Sayda Mahgoub Elbashir
  • MESSENGER RIBONUCLEIC ACIDS FOR ENHANCING IMMUNE RESPONSES AND METHODS OF USE THEREOF
    Publication number: 20200261572
    Abstract: The disclosure features isolated mRNAs encoding a polypeptide that enhances immune responses to an antigen(s) of interest, such as polypeptides that activate Type I interferon pathway signaling or NFkB signaling, including mRNAs comprising one or more modified nucleobase. The disclosure also features methods of using the same, for example, for enhancing immune responses when administered with an antigen(s) of interest, such as to stimulate anti-cancer immune responses or anti-pathogen immune responses.
    Type: Application
    Filed: November 1, 2019
    Publication date: August 20, 2020
    Inventors: Eric Yi-Chun HUANG, Sze-Wah TSE, Jared IACOVELLI, Kristine MCKINNEY, Kristen HOPSON
  • Nucleic acid vaccines
    Patent number: 10709779
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use ribonucleic acid vaccines (NAVs) comprising polynucleotide molecules encoding one or more antigens.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: July 14, 2020
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Axel Bouchon, Eric Yi-Chun Huang
  • CHIKV RNA vaccines
    Patent number: 10702597
    Abstract: Aspects of the disclosure relate to nucleic acid vaccines. The vaccines include one or more RNA polynucleotides having an open reading frame encoding one or more Chikungunya antigen(s), one or more Zika virus antigens, and one or more Dengue antigens. Methods for preparing and using such vaccines are also described.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: July 7, 2020
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Eric Yi-Chun Huang, Kapil Bahl, Tal Zaks, Sunny Himansu, Sayda Mahgoub Elbashir
  • Chikungunya virus RNA vaccines
    Patent number: 10675342
    Abstract: The disclosure relates to tropical diseases such as viral mosquito borne illnesses and the treatment thereof. The invention includes ribonucleic acid vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines for treating and preventing tropical disease.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: June 9, 2020
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu, Eric Yi-Chun Huang, Tal Zaks, Sayda Mahgoub Elbashir
  • PHARMACEUTICAL KIT AND USES THEREOF
    Publication number: 20200163995
    Abstract: Disclosed herein is a pharmaceutical kit for treating cancers. The present pharmaceutical kit comprises an agent and an engineered natural killer cell. The agent is capable of increasing a tumor-associated antigen expression in cancer cells, which can then be targeted and destroyed by the engineered natural killer cell having a tumor-associated antigen-specific chimeric antigen receptor. Also disclosure herein is the uses of the present pharmaceutical kit for the treatment of cancers.
    Type: Application
    Filed: July 23, 2018
    Publication date: May 28, 2020
    Applicant: Johnpro Biotech Inc.
    Inventors: Kwan-Hwa CHI, Yu-Shan WANG, Yi-Chun HUANG, Hsin-Chien CHIANG
  • POP-UP ADJUSTMENT FOR MOBILE DEVICES
    Publication number: 20200133481
    Abstract: Determining the position of a pop-up on a touch screen. Locations of user interactions on a touch screen are determined. Times are also determined for each of the user interactions. A hot spot on the touch screen is defined on the touch screen based on a number of user interactions occurring in proximity of one another during a particular period of time. In one or more embodiments, the particular time period corresponds with a most recent period of time. At least a portion of a pop-up is then displayed within the hot spot on the touch screen for user interaction.
    Type: Application
    Filed: October 29, 2018
    Publication date: April 30, 2020
    Inventors: Hong Gang Liu, Na Fei Yang, Biao Cao, Shi Lin Huang, YaLian Pan, Yi Chun Huang, Shuang Li
  • STORAGE MANAGEMENT FOR DEPLOYMENT OF VIRTUAL MACHINE
    Publication number: 20200065254
    Abstract: A method, computer system, and a computer program product for storage management for deployment of a virtual machine is provided. The present invention may include receiving a request to deploy a virtual machine based on a master VM image. The present invention may also include determining a free disk space for the virtual machine. The present invention may then include determining a disk storage space storing the master VM image. The present invention may further include mapping the disk storage space and the free disk space into a single virtual storage. The present invention may include designating the single virtual storage to be a virtual storage of the virtual machine.
    Type: Application
    Filed: August 21, 2018
    Publication date: February 27, 2020
    Inventors: Biao Cao, Shi Lin Huang, Yi Chun Huang, Shuang Li, Hong Gang Liu, YaLian Pan, Huang Rui, Na Fei Yang
  • USE OF MTOR INHIBITOR AND CHLOROQUINE FOR TREATING CANCER
    Publication number: 20200009127
    Abstract: Disclosed herein are uses of a mammalian target of rapamycin (mTOR) inhibitor and chloroquine or analogue thereof in the manufacture of a medicament for treating cancer patients who are not responsive to a hormone therapy and an immunotherapy. In particular, the medicament is used during the hormone therapy and the immunotherapy to sensitize the patients to the hormone therapy and the immunotherapy.
    Type: Application
    Filed: March 8, 2017
    Publication date: January 9, 2020
    Applicant: Johnpro Biotech Inc.
    Inventors: Kwan-Hwa CHI, Yu-Shan WANG, Yi-Chun HUANG, Hsin-Chien CHIANG
  • Zika virus RNA vaccines
    Patent number: 10517940
    Abstract: The disclosure relates to Zika virus infection and the treatment thereof. The invention includes ribonucleic acid compositions, as well as methods of using the compositions for treating and preventing Zika virus infection.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: December 31, 2019
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu, Eric Yi-Chun Huang, Tal Zaks
  • IMMUNOMODULATORY THERAPEUTIC MRNA COMPOSITIONS ENCODING ACTIVATING ONCOGENE MUTATION PEPTIDES
    Publication number: 20190351039
    Abstract: The disclosure features immunomodulatory therapeutic compositions of an mRNA encoding an activating oncogene mutation peptide and an mRNA encoding a polypeptide that enhances immune responses to the activating oncogene mutation peptide, for example an mRNA encoding an immune potentiator. The disclosure also features methods of using the same, for example, to stimulate anti-cancer immune responses.
    Type: Application
    Filed: February 1, 2018
    Publication date: November 21, 2019
    Inventors: Eric Yi-Chun HUANG, Sze-Wah TSE, Jared IACOVELLI, Kristine MCKINNEY, Nicholas VALIANTE
  • Zika RNA vaccines
    Patent number: 10449244
    Abstract: Aspects of the disclosure describe compositions that comprise RNA polynucleotides having an open reading frame encoding one or more Zika virus antigens. Methods for preparing and using the compositions are also described.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: October 22, 2019
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Eric Yi-Chun Huang, Kapil Bahl, Tal Zaks, Sunny Himansu
  • Industrial input/output device with movable connector
    Patent number: 10365696
    Abstract: An industrial input/output device with movable connector is provided. The industrial input/output device with movable connector is controlled to make the first connector provide connection or not by moving a moving link thereof. Therefore, the technical effect of preventing the interruption of the operation of the industrial input/output device can be achieved.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: July 30, 2019
    Assignee: MOXA INC.
    Inventors: Yi-Chun Huang, Chung-Kun Hou
  • Clamping mechanism for industrial input/output device
    Patent number: 10367295
    Abstract: The present disclosure illustrates a clamping mechanism for an industrial input/output device. In the clamping mechanism, an operating link can be slid and rotated to drive links of mechanism elements. Therefore, the efficiency of clamping the industrial input/output device on a DIN rail or unloading the industrial input/output device from the DIN rail fast and conveniently may be achieved.
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: July 30, 2019
    Assignee: MOXA INC.
    Inventor: Yi-Chun Huang
  • COMPOSITIONS AND METHODS FOR TOLERIZING CELLULAR SYSTEMS
    Publication number: 20190192653
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of molecules for tolerizing cellular systems.
    Type: Application
    Filed: August 3, 2018
    Publication date: June 27, 2019
    Inventors: Stephen G. Hoge, Eric Yi-Chun Huang
  • IMMUNOMODULATORY THERAPEUTIC MRNA COMPOSITIONS ENCODING ACTIVATING ONCOGENE MUTATION PEPTIDES
    Publication number: 20190175727
    Abstract: The disclosure features immunomodulatory therapeutic compositions of an mRNA encoding an activating oncogene mutation peptide and an mRNA encoding a polypeptide that enhances immune responses to the activating oncogene mutation peptide, for example an mRNA encoding an immune potentiator. The disclosure also features methods of using the same, for example, to stimulate anti-cancer immune responses.
    Type: Application
    Filed: February 19, 2019
    Publication date: June 13, 2019
    Inventors: Eric Yi-Chun HUANG, Sze-Wah TSE, Jared IACOVELLI, Kristine MCKINNEY, Nicholas VALIANTE
  • SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREOF
    Publication number: 20190139815
    Abstract: In a method for manufacturing a semiconductor device, a first dielectric layer is formed over a substrate. A first set of recesses is formed in the first dielectric layer. A metal layer is formed in the first set of recesses. A set of metal wirings is formed from the metal layer in the first set of recesses. A second set of recesses is formed in the first dielectric layer. A second dielectric layer is formed over the set of metal wirings and in the second set of recesses. A third set of recesses is formed in the first dielectric layer and the second dielectric layer. A third dielectric layer is formed over the metal wirings and in the third set of recesses.
    Type: Application
    Filed: December 28, 2018
    Publication date: May 9, 2019
    Inventors: Yi-Chun HUANG, Chih-Hsiang YAO, Jye-Yen CHENG