Patents by Inventor Yi-Chun Huang

Yi-Chun Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MESSENGER RIBONUCLEIC ACIDS FOR ENHANCING IMMUNE RESPONSES AND METHODS OF USE THEREOF
    Publication number: 20180311343
    Abstract: The disclosure features isolated mRNAs encoding a polypeptide that enhances immune responses to an antigen(s) of interest, such as polypeptides that activate Type I interferon pathway signaling or NFkB signaling, including mRNAs comprising one or more modified nucleobase. The disclosure also features methods of using the same, for example, for enhancing immune responses when administered with an antigen(s) of interest, such as to stimulate anti-cancer immune responses or anti-pathogen immune responses.
    Type: Application
    Filed: June 1, 2018
    Publication date: November 1, 2018
    Inventors: Eric Yi-Chun HUANG, Sze-Wah TSE, Jared IACOVELLI, Kristine MCKINNEY, Kristen HOPSON
  • MODIFIED POLYNUCLEOTIDES FOR ALTERING CELL PHENOTYPE
    Publication number: 20180291335
    Abstract: The present invention relates to compositions, methods and kits using cell phenotype altering polynucleotides, cell phenotype altering primary transcripts and cell phenotype altering mmRNA molecules.
    Type: Application
    Filed: November 16, 2017
    Publication date: October 11, 2018
    Inventors: Stephane Bancel, Antonin de Fougerolles, Susan Whoriskey, Tirtha Chakraborty, Eric Yi-Chun Huang
  • ZIKA RNA VACCINES
    Publication number: 20180280496
    Abstract: Aspects of the disclosure relate to nucleic acid vaccines. The vaccines include one or more RNA polynucleotides having an open reading frame encoding one or more Chikungunya antigen(s), one or more Zika virus antigens, and one or more Dengue antigens. Methods for preparing and using such vaccines are also described.
    Type: Application
    Filed: June 15, 2018
    Publication date: October 4, 2018
    Applicant: ModernaTX, Inc.
    Inventors: GIUSEPPE CIARAMELLA, ERIC YI-CHUN HUANG, KAPIL BAHL, TAL ZAKS, SUNNY HIMANSU
  • Nucleic acid vaccines
    Patent number: 10022435
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use ribonucleic acid vaccines (NAVs) comprising polynucleotide molecules encoding one or more antigens.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: July 17, 2018
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Axel Bouchon, Eric Yi-Chun Huang
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF OPHTHALMIC DISEASES AND CONDITIONS
    Publication number: 20180085391
    Abstract: The present invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides in the treatment, prevention and/or amelioration of ophthalmic disease or conditions.
    Type: Application
    Filed: August 7, 2015
    Publication date: March 29, 2018
    Inventors: Axel Bouchon, Eric Yi-Chun Huang
  • LONG-LIVED POLYNUCLEOTIDE MOLECULES
    Publication number: 20180086816
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of long-lived polynucleotides, primary transcripts and mmRNA molecules.
    Type: Application
    Filed: May 10, 2017
    Publication date: March 29, 2018
    Inventors: Stephen G. Hoge, Eric Yi-Chun Huang, Tirtha Chakraborty, Sayda M. Elbashir
  • Modified polynucleotides for the production of cosmetic proteins and peptides
    Patent number: 9878056
    Abstract: The invention relates to cosmetic mRNAs encoding elastin, and methods of using such mRNAs.
    Type: Grant
    Filed: March 9, 2013
    Date of Patent: January 30, 2018
    Assignee: ModernaTX, Inc.
    Inventors: Stephane Bancel, Eric Yi-Chun Huang
  • Nucleic acid vaccines
    Patent number: 9872900
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use ribonucleic acid vaccines (NAVs) comprising polynucleotide molecules encoding one or more antigens.
    Type: Grant
    Filed: April 5, 2016
    Date of Patent: January 23, 2018
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Axel Bouchon, Eric Yi-Chun Huang
  • CHIKAGUNYA VIRUS RNA VACCINES
    Publication number: 20180008694
    Abstract: The disclosure relates to tropical diseases such as viral mosquito borne illnesses and the treatment thereof. The invention includes ribonucleic acid vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines for treating and preventing tropical disease.
    Type: Application
    Filed: August 11, 2017
    Publication date: January 11, 2018
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu, Eric Yi-Chun Huang, Tal Zaks
  • TOLEROGENIC COMPOSITIONS AND METHODS
    Publication number: 20170348415
    Abstract: The invention relates to tolerogenic compositions and methods for the preparation, manufacture and therapeutic use thereof.
    Type: Application
    Filed: September 3, 2015
    Publication date: December 7, 2017
    Inventors: Stephen G. HOGE, Eric Yi-Chun HUANG, Louis Saint Laurence O'DEA
  • ZIKA VIRUS RNA VACCINES
    Publication number: 20170340724
    Abstract: The disclosure relates to tropical diseases such as viral mosquito borne illnesses and the treatment thereof. The invention includes ribonucleic acid vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines for treating and preventing tropical disease.
    Type: Application
    Filed: August 11, 2017
    Publication date: November 30, 2017
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu, Eric Yi-Chun Huang, Tal Zaks
  • Interconnect structures and methods of forming same
    Patent number: 9793212
    Abstract: An embodiment semiconductor device includes a first conductive feature in a dielectric layer and a second conductive feature over the dielectric layer and electrically connected to the first conductive feature. The second conductive feature includes a dual damascene structure and further includes a top portion within both a line portion and a via portion of the second conductive feature and a bottom portion in the via portion of the second conductive feature. The bottom portion comprises a different conductive material than the top portion, and a thickness of the bottom portion is at least about twenty percent of a total thickness of the via portion of the second conductive feature.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: October 17, 2017
    Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Yi-Chun Huang, Chih-Hsiang Yao, Jye-Yen Cheng, Wen-Chuan Chiang, Ying-Wen Huang
  • SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREOF
    Publication number: 20170271198
    Abstract: In a method for manufacturing a semiconductor device, a first dielectric layer is formed over a substrate. A first set of recesses is formed in the first dielectric layer. A metal layer is formed in the first set of recesses. A set of metal wirings is formed from the metal layer in the first set of recesses. A second set of recesses is formed in the first dielectric layer. A second dielectric layer is formed over the set of metal wirings and in the second set of recesses. A third set of recesses is formed in the first dielectric layer and the second dielectric layer. A third dielectric layer is formed over the metal wirings and in the third set of recesses.
    Type: Application
    Filed: June 7, 2017
    Publication date: September 21, 2017
    Inventors: Yi-Chun HUANG, Chih-Hsiang YAO, Jye-Yen CHENG
  • MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF INTRABODIES
    Publication number: 20170210788
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of modified polynucleotides comprising at least one intrabody construct.
    Type: Application
    Filed: July 23, 2015
    Publication date: July 27, 2017
    Inventors: Eric Yi-Chun HUANG, Josh FREDERICK, Kristine MCKINNEY, Christina HENDERSON
  • SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREOF
    Publication number: 20170207112
    Abstract: In a method for manufacturing a semiconductor device, a first dielectric layer is formed over a substrate. A first set of recesses is formed in the first dielectric layer. A metal layer is formed in the first set of recesses. A set of metal wirings is formed from the metal layer in the first set of recesses. A second set of recesses is formed in the first dielectric layer. A second dielectric layer is formed over the set of metal wirings and in the second set of recesses. A third set of recesses is formed in the first dielectric layer and the second dielectric layer. A third dielectric layer is formed over the metal wirings and in the third set of recesses.
    Type: Application
    Filed: January 20, 2016
    Publication date: July 20, 2017
    Inventors: Yi-Chun Huang, Chih-Hsiang Yao, Jye-Yen Cheng
  • Semiconductor device and manufacturing method thereof
    Patent number: 9711391
    Abstract: In a method for manufacturing a semiconductor device, a first dielectric layer is formed over a substrate. A first set of recesses is formed in the first dielectric layer. A metal layer is formed in the first set of recesses. A set of metal wirings is formed from the metal layer in the first set of recesses. A second set of recesses is formed in the first dielectric layer. A second dielectric layer is formed over the set of metal wirings and in the second set of recesses. A third set of recesses is formed in the first dielectric layer and the second dielectric layer. A third dielectric layer is formed over the metal wirings and in the third set of recesses.
    Type: Grant
    Filed: January 20, 2016
    Date of Patent: July 18, 2017
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD.
    Inventors: Yi-Chun Huang, Chih-Hsiang Yao, Jye-Yen Cheng
  • TARGETED ADAPTIVE VACCINES
    Publication number: 20170173128
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotide molecules for targeted adaptive vaccines (TAVs).
    Type: Application
    Filed: December 8, 2014
    Publication date: June 22, 2017
    Inventors: Stephen G. Hoge, Eric Yi-Chun Huang
  • Multiband Filter Circuitry, Multiband Duplexer Circuitry, and Related Radio-Frequency System
    Publication number: 20170012763
    Abstract: A multiband filter circuitry utilized in a radio-frequency (RF) system is disclosed. The multiband filter circuitry operates at a plurality of operating frequency bands. The multiband filter circuitry comprises at least a switchable-filtering series. Each of the at least a switchable-filtering series comprises a first terminal coupled between the antenna and the RF processing unit; a second terminal coupled to a ground; and a plurality of switchable-filtering units connected in series, each comprising a filtering unit; and a switching unit, connected to the filtering unit in parallel.
    Type: Application
    Filed: July 8, 2015
    Publication date: January 12, 2017
    Inventors: Min-Shou Wu, Lien Chien, Yi-Chun Huang
  • POLYNUCLEOTIDES FOR THE IN VIVO PRODUCTION OF ANTIBODIES
    Publication number: 20170002060
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding an antibody, variant or fragment.
    Type: Application
    Filed: January 8, 2015
    Publication date: January 5, 2017
    Inventors: Joseph Beene Bolen, Axel Bouchon, Giuseppe Ciaramella, Eric Yi-Chun Huang
  • NUCLEIC ACID VACCINES
    Publication number: 20160331828
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use ribonucleic acid vaccines (NAVs) comprising polynucleotide molecules encoding one or more antigens.
    Type: Application
    Filed: April 5, 2016
    Publication date: November 17, 2016
    Applicant: Moderna Therapeutics, Inc.
    Inventors: Giuseppe Ciaramella, Axel Bouchon, Eric Yi-Chun Huang