Abstract: The present invention provides compounds of the formula below pharmaceutically acceptable salts of the compounds, methods of treating patients for liver disease, and processes for preparing the compounds.

Abstract: Data is replicated between primary and secondary storage systems using a data pulling process or a log shipping process. If data is to be replicated through the log shipping process, a transaction and its associated data get stored in a transaction log in the secondary storage system. Subsequently, when the transaction gets executed, actual data gets persisted from the transaction log to a data log in the secondary storage system. If the data is to be replicated through the data pulling process, the transaction is stored in the transaction log. However, the associated data for the transaction is retrieved from the first primary storage system and stored directly in the data log in the secondary system.

Abstract: A distributed storage system includes multiple partitions. A block received for storage is striped across the partitions if it meets predetermined criteria. Multiple tables are maintained for indexing the blocks and the subblocks of blocks that are partitioned. The tables for the subblocks and the tables for the corresponding blocks of the subblocks are updated to include metadata for the subblocks for retrieving the subblocks in response to a request for a corresponding stored block.

Abstract: Provided are novel compounds of Formula I: pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula I and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: A method for fabricating semiconductor device includes the steps of: forming a fin-shaped structure on a substrate; forming a shallow trench isolation (STI) around the fin-shaped structure; forming a liner on the fin-shaped structure; and removing the liner and part of the fin-shaped structure so that a sidewall of the fin-shaped structure comprises a curve. Moreover, the method includes forming an epitaxial layer around the sidewall of the fin-shaped structure while a top surface of the fin-shaped structure is exposed.

Abstract: A method for intracellular delivery of single proteins or other cargo molecules by encapsulation within nanocapsules formed by interfacial polymerization of one or more types of monomers and selected protease cleavable cross-linkers is provided. The thin positively charged capsules are readily brought into the cytosol of target cells by endocytosis. The capsules are degraded by the action of endogenous proteases or co-delivered proteases on the cross-linkers releasing the functional cargo unaltered. The cross-linkers can be adapted to be cleavable by specific enzymes selected from available intracellular enzymes within the target cell or co-delivered or self-cleaving when the cargo itself is a protease. The nanocapsules produced by the methods have been shown to have long-term stability, high cell penetration capability, low toxicity and efficient protease-modulated specific degradability without affecting cargo protein function.

Abstract: Aspects of the present disclosure describe receiving an indication of a covariance matrix from an access point, receiving downlink signaling from the access point, deriving, based at least in part on the covariance matrix or the downlink signaling, one or more precoders for uplink communications over an uplink channel, and indicating, based at least in part on the one or more precoders, uplink channel feedback to the access point.

Abstract: Provided are a quinazoline derivative, a pharmaceutical composition containing the same, a method for preparation of said derivative, and an application of same as an anti-cancer drug.

Abstract: The present invention provides compounds of the formula below pharmaceutically acceptable salts of the compounds, methods of treating patients for liver disease, and processes for preparing the compounds.

Abstract: A lensed beam-splitter prism array includes a beam-splitter substrate with a plurality of planar and parallel thin-film coatings each spanning a top substrate surface and a bottom substrate surface, and making an oblique angle therebetween, and a lens form layer formed on the top surface and having a plurality of lens forms, each lens form being above one of the plurality of coatings. A method for fabricating a lensed beam-splitter prism includes bonding a plurality of substrates to form a substrate stack having a coating between each adjacent substrate pair. The method also includes forming a stack slice by applying a plurality of parallel cuts at an oblique angle with respect to each coating. Each coating spans a first stack-slice surface and a second stack-slice surface opposing the first stack-slice surface. The method also includes forming a lens form layer on the first stack-slice surface spanning one or more coatings.

Abstract: Embodiments of the present invention provide methods for optimizing a lithographic projection apparatus including optimizing projection optics therein. The current embodiments include several flows including optimizing a source, a mask, and the projection optics and various sequential and iterative optimization steps combining any of the projection optics, mask and source. The projection optics is sometimes broadly referred to as “lens”, and therefore the optimization process may be termed source mask lens optimization (SMLO). SMLO may be desirable over existing source mask optimization process (SMO) or other optimization processes that do not include projection optics optimization, partially because including the projection optics in the optimization may lead to a larger process window by introducing a plurality of adjustable characteristics of the projection optics.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: A probe card includes a probe seat having upper and lower dies and a probe accommodating hole, a spring probe inserted through the probe accommodating hole and including a spring sleeve having upper and lower non-spring sections, and a circuit board disposed on the upper die and having a contact pad against which the spring probe is abutted. At least one of the upper and lower dies has a stopping surface partially facing the probe accommodating hole and an extended portion inserting hole in alignment with the probe accommodating hole. At least one of the upper and lower non-spring sections has a cylinder portion abutted on the stopping surface and an extended portion inserted through the extended portion inserting hole.

Abstract: The present invention provides a method for preparing a rare earth permanent magnet material. The preparation method of the present invention comprises atomizing spray process and infiltrating process, wherein the atomizing-sprayed sintered rare earth magnet is placed in a closed container before infiltrating. Through the atomizing spray process a solution containing a heavy rare earth element is coated on the surface of a sintered R1-Fe(Co)—B-A-X-M rare earth magnet, and after baking, heat treatment is performed to infiltrate the sprayed heavy rare earth element to the grain boundary phase of the sintered rare earth magnet. This method decreases the amount of a heavy rare earth element used, increases the coercive force of magnets with a little decrease of remanence, decreases the remanence temperature coefficient and coercive force temperature coefficient of the magnet, and improves resistance of the magnet against demagnetization at a high temperature.