Patents by Inventor Yi-Han Dai

Yi-Han Dai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11672827
    Abstract: Disclosed herein are a pharmaceutical composition and a disease therapy method. The pharmaceutical composition relates to an artificial chimeric antigen receptor (CAR). Specifically, the pharmaceutical composition includes a CAR protein that is highly specific to CD19 antigen, a vector that is capable of inducing a cell to generate the certain CAR 19 protein and a population of a modified mammal cell including the CAR19 protein, the vector or combination thereof. Furthermore, the artificial CAR19 includes a CD19 antigen-binding fragment, a transmembrane domain, and a signaling domain. The CD19 antigen-binding fragment is a single-chain variable fragment (scFv) having specific amino acid sequences. Additionally, the method relates to a cancer therapy by using said modified mammal cells. Furthermore, the method includes the steps of purifying a population of autologous cells, modifying the population of autologous cells with an artificial CAR, and administrating the modified autologous cells.
    Type: Grant
    Filed: August 9, 2018
    Date of Patent: June 13, 2023
    Inventors: Te-Ling Pang, Ming Chin Ko, Yi Han Dai, Yi-Ting Lai
  • Publication number: 20210069244
    Abstract: Disclosed herein provides a pharmaceutical composition and a disease therapy method. The pharmaceutical composition relates to an artificial chimeric antigen receptor (CAR). Specifically, the pharmaceutical composition includes a CAR protein that is highly specific to CD19 antigen, a vector that is capable of inducing a cell to generate the certain CAR 19 protein and a population of a modified mammal cell including the CAR19 protein, the vector or combination thereof. Furthermore, the artificial CAR19 includes a CD19 antigen-binding fragment, a transmembrane domain, and a signaling domain. The CD19 antigen-binding fragment is a single-chain variable fragment (scFv) having specific amino acid sequences. Additionally, the method relates to a cancer therapy by using said modified mammal cells. Furthermore, the method includes the steps of purifying a population of autologous cells, modifying the population of autologous cells with an artificial CAR, and administrating the modified autologous cells.
    Type: Application
    Filed: August 9, 2018
    Publication date: March 11, 2021
    Applicant: UWELL BIOPHARMA INC.
    Inventors: TE-LING PANG, MING CHIN KO, YI HAN DAI, YI-TING LAI
  • Patent number: D618246
    Type: Grant
    Filed: September 10, 2009
    Date of Patent: June 22, 2010
    Assignee: Hon Hai Precision Industry Co., Ltd.
    Inventor: Yi-Han Dai
  • Patent number: D618247
    Type: Grant
    Filed: November 2, 2009
    Date of Patent: June 22, 2010
    Assignee: Hon Hai Precision Industry Co., Ltd.
    Inventor: Yi-Han Dai
  • Patent number: D618690
    Type: Grant
    Filed: November 2, 2009
    Date of Patent: June 29, 2010
    Assignee: Hon Hai Precision Industry Co., Ltd.
    Inventor: Yi-Han Dai