Abstract: The presently-disclosed subject matter relates to RNA-based composition and method to treat breast cancer in a subject. More particularly, the presently disclosed subject matter relates to a RNA nanostructure and composition containing a multiple branched RNA nanoparticle, a breast cancer targeting module, and an effective amount of a breast cancer therapeutic agent. Further, the presently disclosed subject matter relates to a method of using the RNA nanoparticle composition to treat breast cancer in a subject having or at risk of having breast cancer.

Abstract: A flexible solar cell chip packaging box includes a housing body and a housing cover. The housing body includes a bottom wall and a first side wall which is perpendicularly and fixedly connected to the bottom wall, the first side wall and the bottom wall enclose a receiving chamber provided with an opening, and the first side wall is provided with a first groove. The housing cover includes a top wall and a second side wall which is perpendicularly and fixedly connected to the top wall, the top wall is covered on the opening, and the second side wall is sleeved on the outside of the first side wall.

Abstract: The presently-disclosed subject matter relates to RNA-based composition and method to treat gastric cancer in a subject. More particularly, the presently disclosed subject matter relates to a RNA nanostructure and composition containing a multiple branched RNA nanoparticle, a gastric cancer targeting module, and an effective amount of a therapeutic agent. Further, the presently disclosed subject matter relates to a method of using the RNA nanoparticle composition to treat gastric cancer in a subject having or at risk of having gastric cancer.

Abstract: A key structure includes a base plate, an illumination module, a switch circuit board, a metallic elastic element, a supporting element, a metallic pressing plate and a covering member. The metallic elastic element is disposed on the switch circuit board. The supporting element is located beside the metallic elastic element. An edge of the metallic pressing plate is fixed on the supporting element. As the metallic pressing plate is swung relative to the base plate to push the metallic elastic element, the switch circuit board is triggered by the metallic elastic element. The covering member covers the base plate and the metallic pressing plate. The covering member has a light-transmissible region. A light beam from the illumination module passes through the light-transmissible region. Consequently, the key structure is illuminated.

Abstract: This disclosure describes engineered biosynthetic pathways, recombinant cells, and methods relating to biosynthesis of esters. The recombinant cells may be modified to exhibit increased biosynthesis of an ester compared to a wild-type control. The recombinant cell may be incubated in medium that includes a carbon source under conditions effective for the recombinant cell to produce an ester. This disclosure also describes a method that generally includes introducing into a host cell a heterologous polynucleotide encoding at least one polypeptide that catalyzes a step in converting a carbon source to an ester, wherein the at least one polynucleotide is operably linked to a promoter so that the modified host cell catalyzes conversion of the carbon source to an ester.

Abstract: A keyboard includes a base plate, a switch circuit board, plural swinging-type key structures, a light-emitting element, a light guide plate and a covering member. The light-emitting element emits a light beam. The plural swinging-type key structures are disposed on the switch circuit board. When one of the swinging-type key structures is pressed, the switch circuit board is triggered to generate a key signal. The light guide plate comprises plural light guide sub-plates. The light guide sub-plates are disposed on the corresponding swinging-type key structures. The covering member covers the base plate and the light guide plate. The covering member has a light-transmissible region. The light beam from the light-emitting element passes through the light-transmissible region. Consequently, the key structure is illuminated.

Abstract: A key structure includes a base plate, an illumination module, a switch circuit board, a metallic elastic element, a supporting element, a metallic pressing plate and a covering member. The metallic elastic element is disposed on the switch circuit board. The supporting element is located beside the metallic elastic element. An edge of the metallic pressing plate is fixed on the supporting element. As the metallic pressing plate is swung relative to the base plate to push the metallic elastic element, the switch circuit board is triggered by the metallic elastic element. The covering member covers the base plate and the metallic pressing plate. The covering member has a light-transmissible region. A light beam from the illumination module passes through the light-transmissible region. Consequently, the key structure is illuminated.

Abstract: A key structure includes a base plate, a keycap and a connecting element. The connecting element includes a first frame and a second frame. The first frame is connected with the base plate and the keycap. The first frame includes a first linking part. The second frame is connected with the base plate and the keycap. The second frame includes a second linking part. The second linking part is contacted with the first linking part. When a depressing force from the user is applied to the keycap, the first frame is swung relative to the second frame. Moreover, in response to a friction between the first linking part and the second linking part, the keycap is correspondingly moved.

Abstract: A key structure includes a base plate, a keycap and a connecting element. The connecting element includes a first frame and a second frame. The first frame is connected with the base plate and the keycap. The first frame includes a first linking part. The second frame is connected with the base plate and the keycap. The second frame includes a second linking part. The second linking part is contacted with the first linking part. When a depressing force from the user is applied to the keycap, the first frame is swung relative to the second frame. Moreover, in response to a friction between the first linking part and the second linking part, the keycap is correspondingly moved.

Abstract: Disclosed herein is a radioimmune complex comprising an epidermal growth factor receptor (EGFR)-targeted antibody and a radioactive isotope of rhenium labeled thereon. The EGFR-targeted antibody is cetuximab or panitumumab.

Abstract: According to an embodiment of the present disclosure, a roll-to-roll apparatus may include an unwinding unit, a winding unit, at least one supporting unit, at least one breakage sensor, and at least one holding unit. The at least one supporting unit is disposed between the unwinding unit and the winding unit, and supports the flexible substrate to move from the unwinding unit to the winding unit. The at least one breakage sensor may sense whether the flexible substrate is broken or not. The at least one holding unit may grip the flexible substrate while a breakage of the flexible substrate is sensed by the at least one breakage sensor.

Abstract: An optical touch system includes a plurality of touch devices and an electronic device. The electronic device includes a touch display unit configured to generate a plurality of touch points when the plurality of touch devices are contacted thereon, a control unit configured to divide the plurality of touch devices into a plurality of groups according to characteristics of the plurality of touch devices to control or handle operations of the plurality of groups in time division, an optical device configured to obtain images corresponding to touch points generated by touch devices in one of the plurality of groups, and a calculating unit configured to receive the images obtained by the optical device to calculate positions of the touch points corresponding to the images.

Abstract: A power supply device includes a power conversion module and a power regulating module. The power conversion module is configured to convert an AC electric power into a DC electric power. The power regulating module includes a microprocessor, a voltage-dividing resistor, a constant-voltage regulator, and a constant-current regulator. The voltage-dividing resistor is electrically connected to the setting resistor and the microprocessor. The constant-voltage regulator is electrically connected to the power conversion module, the dividing resistor, and the setting resistor; The constant-current regulator is electrically connected to the power conversion module and the microprocessor.

Abstract: This disclosure describes methods for screening heterologous coding regions (e.g., a single gene coding region, and operon, or other gene cluster) for the ability to genetically modify a host cell to perform nonphosphorylative biosynthesis of 2,5-dioxopentanoate and downstream derivatives thereof (e.g., 1,4-butanediol, glutamate, or glutaconate. This disclosure further describes recombinant cells modified to increase nonphosphorylative biosynthesis of 2,5-dioxopentanoate compared to an appropriate control cell (e.g., a wild-type cell or an otherwise genetically-modified cell) and methods of using making and using such recombinant cells.

Abstract: A key structure includes a base, a keycap, a first longitudinal bar, a second longitudinal bar, a first transverse bar and a second transverse bar. The first longitudinal bar, the second longitudinal bar, the first transverse bar and the second transverse bar are uniformly distributed in the range of the keycap. Consequently, the keycap is stably moved relative to the base. The first longitudinal bar, the second longitudinal bar, the first transverse bar and the second transverse bar are made of a metallic material. Since these bars are thinner than the scissors-type connecting element of the conventional key structure, the key structure of the present invention has reduced thickness. Moreover, since these bars are made of the metallic material, the structural strength of the key structure is increased.

Abstract: A power supply device includes a power conversion module and a power regulating module. The power conversion module is configured to convert an AC electric power into a DC electric power. The power regulating module includes a microprocessor, a voltage-dividing resistor, a constant-voltage regulator, and a constant-current regulator. The voltage-dividing resistor is electrically connected to the setting resistor and the microprocessor. The constant-voltage regulator is electrically connected to the power conversion module, the dividing resistor, and the setting resistor; The constant-current regulator is electrically connected to the power conversion module and the microprocessor.

Abstract: An auto-sensing dimming lamp guides ambient light to a sensor installed in a lamp cover and at a base through a light pipe. The auto-sensing dimming lamp automatically adjusts a light emission status of LED light sources according to the ambient light by a processor installed at the base. The processor includes a pass filter unit and a modulation unit, and the pass filter unit receives a detected signal waveform of the sensor and a driving voltage waveform of the LED light sources.

Abstract: A light emitting diode (LED) driving device with control based on LED setting resistance is disclosed. The LED driving device is applied to an LED lighting fixture having a setting resistor and is configured to modulate output voltage and output current according to the setting resistor to fit the power requirement of the LED lighting fixture. The LED driving device includes a power conversion module and a driving module. The driving module includes a microprocessor and controlling unit. The microprocessor is electrically connected to the LED lighting fixture for sensing the setting resistor and generates a controlling signal in accordance with the sensed setting resistor to the controlling unit. The controlling unit is electrically connected to the microprocessor and the power conversion module and configured to drive the power conversion module to modulate output current and output voltage according to the controlling signal.

Abstract: An auto-sensing dimming lamp guides ambient light to a sensor installed in a lamp cover and at a base through a light pipe. The auto-sensing dimming lamp automatically adjusts a light emission status of LED light sources according to the ambient light by a processor installed at the base. The processor includes a pass filter unit and a modulation unit, and the pass filter unit receives a detected signal waveform of the sensor and a driving voltage waveform of the LED light sources.