Abstract: The present invention provides compositions and methods comprising chimeric antigen receptors (CARs) wherein the ‘Signal 1’ has been optimized, for example wherein the CAR comprises an intracellular domain comprising a truncated version of CD3?, a FcR? or portion thereof, or a hybrid of CD3? and CD3?. Compositions and methods of treatment are also provided.

Abstract: A metal member for a household appliance includes a first surface and a second surface connected to each other. The second surface is inclined with respect to the first surface, and the second surface has a reflectivity higher than that of the first surface. A household appliance having the metal member is also provided.

Abstract: Disclosed is a novel timer module. The novel timer module includes a replaceable movement, a master control circuit board, an upper housing, and a lower housing. A circuit board is disposed inside the replaceable movement. Five first inserting pins are welded on the circuit board. The first inserting pins are exposed from the outside of a housing of the replaceable movement. The master control circuit board is located in the upper housing and the lower housing, and is fixed on an upper surface of the lower housing. A relay is disposed inside the master control circuit board. Contacts of the relay respectively extend and are fixed on a surface of the master control circuit board by using leads. Therefore, a problem that a conventional timer movement is fixedly welded on a circuit of a timer module can be resolved.

Abstract: A titanium aluminide (TiAl) coating capable of improving high-temperature oxidation resistance of titanium alloys and a preparation method thereof are provided. The TiAl coating includes ?-AlF3 nanoparticles, and a content of the ?-AlF3 nanoparticles is 5-30 vol. % of the TiAl coating. The preparation method of the TiAl coating includes: using a TiAl alloy target and an ?-AlF3 target as raw materials, and performing magnetron sputtering on a substrate surface to prepare a coating; the magnetron sputtering is double-target co-sputtering, and a substrate temperature during the magnetron sputtering is 150° C., the TiAl alloy target is performed direct current sputtering with a power of 0.5-2 kW, and the ?-AlF3 target is performed radio frequency sputtering with a power of 0.07-0.2 kW. After the coating is obtained by the double-target co-sputtering, the obtained coating is heat-treated at 600-800° C. for 5-20 h to obtain a final coating.

Abstract: Disclosed is a novel timer module. The novel timer module includes a replaceable movement, a master control circuit board, an upper housing, and a lower housing. A circuit board is disposed inside the replaceable movement. Five first inserting pins are welded on the circuit board. The first inserting pins are exposed from the outside of a housing of the replaceable movement. The master control circuit board is located in the upper housing and the lower housing, and is fixed on an upper surface of the lower housing. A relay is disposed inside the master control circuit board. Contacts of the relay respectively extend and are fixed on a surface of the master control circuit board by using leads. Therefore, a problem that a conventional timer movement is fixedly welded on a circuit of a timer module can be resolved.

Abstract: A metal member for a household appliance includes a first surface and a second surface connected to each other. The second surface is inclined with respect to the first surface, and the second surface has a reflectivity higher than that of the first surface. A household appliance having the metal member is also provided.

Abstract: The present invention relates to the use of a combination of D-panthenol, allantoin and oat kernel extract in protecting mast cells thereby anti-allergy. The present invention also provides an anti-allergic cosmetic composition having the function of protecting mast cells, comprising a combination of D-panthenol, allantoin and oat kernel extract, and ingredients commonly used in cosmetics; and an anti-allergic cosmetic method, comprising applying the cosmetic composition to the skin.

Abstract: It is described an information processing method. On a display screen of a terminal it is presented at least one piece of promotion information associated with an application when the application is running on the terminal. Upon detecting that one piece of the promotion information is selected, a payment platform which is in-built in the application is triggered to perform the following: requesting a server to determine whether a payment option corresponding to the selected piece of the promotion information shall be presented on a first page or a second page; jumping to the first page upon reception from the server of a first operation instruction of presenting the payment option corresponding to the selected piece of the promotion information on the first page; and presenting on the first page the payment option corresponding to the selected piece of the promotion information.

Abstract: The present invention relates to novel compositions and uses thereof as antioxidants and/or neuroprotective agents for the treatment of medical conditions associated with oxidative stress and/or neural damage, such as, for example, neurological diseases, disorders and trauma, and hence in the treatment of CNS-associated diseases, disorders and trauma.

Abstract: A film profile forming device includes a supporting table, a screw coupled to the supporting table in a perpendicular direction, a motor arranged on an end of the screw for rotating the screw, a guiding base having a screw hole engaged with the screw being driven by the screw for dispersing force and moving in the perpendicular direction, a lower base fixed under the supporting table, and a upper base glidingly arranged between the supporting table and the lower base. The upper base is brought by the guiding base and moves to and fro in the perpendicular direction to close or away from the lower base.

Abstract: A film thermoforming method includes inserting a film prefabricated material need to be thermoformed into a lower die of a thermoforming device. The thermoforming device includes an upper die movable to-and-fro opposite to the lower die based on the shape of a film product. The upper die moves downwards gradually to press from a predetermined manufacturing height and then moves upwards to release the prefabricated material by a cycle mode, and the method decreases gradually the manufacturing height of the upper die for thermoforming the film product in a predetermined time. The present method can improve the precision and the quality of the film product, and can decrease largely the manufacturing time.