Abstract: A system and method for evaluating driver performance is provided. The system includes a GPS navigation module for locating a running vehicle; a running vehicle data collection module for collecting data of the vehicle; a vehicle specifications memory for storing specifications of the vehicle; a road maps memory for storing maps of an area so as to identify the location of the vehicle by cooperating with the GPS navigation module; a road evaluation parameters memory for storing road evaluation parameters of the vehicle, and outputting evaluation parameters of the vehicle by cooperating with the road maps memory; and an evaluation module for combining the data of the vehicle from the running vehicle data collection module, the road evaluation parameters of the vehicle from the road evaluation parameters memory, and the specifications of the vehicle from the vehicle specifications memory, evaluating the combination, and outputting an evaluation report.

Abstract: Methods for identifying a candidate compound with an ability to modulate cation transport through a transient receptor potential (TRP) channel in a cell are disclosed. The methods can include (a) providing a cell expressing a recombinant nucleic acid sequence encoding an transient receptor potential (TRP) channel gene product or a functional fragment or derivative thereof; (b) contacting the cell with the candidate compound; (c) comparing cation transport in the cell in the absence of the candidate compound with cation transport in the cell in the presence of the candidate compound; and (d) identifying a candidate compound through the comparing step that modulates cation transport in the cell through the transient receptor potential (TRP) channel. Also disclosed are nucleic acid and amino acid sequences for insect TRP channel gene products, antibodies that bind to the disclosed TRP channels, and recombinant host cells the include the disclosed biosequences.

Abstract: Methods for identifying a candidate compound with an ability to modulate cation transport through a transient receptor potential (TRP) channel in a cell are disclosed. The methods can include (a) providing a cell expressing a recombinant nucleic acid sequence encoding an transient receptor potential (TRP) channel gene product or a functional fragment or derivative thereof; (b) contacting the cell with the candidate compound; (c) comparing cation transport in the cell in the absence of the candidate compound with cation transport in the cell in the presence of the candidate compound; and (d) identifying a candidate compound through the comparing step that modulates cation transport in the cell through the transient receptor potential (TRP) channel. Also disclosed are nucleic acid and amino acid sequences for insect TRP channel gene products, antibodies that bind to the disclosed TRP channels, and recombinant host cells the include the disclosed biosequences.