Patents by Inventor Yihan Zhang

Yihan Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250074908
    Abstract: A salt of a ROCK inhibitor, a crystal form of the salt, a composition, and a pharmaceutical use are provided. The salt and the crystal form of the salt are an acid addition salt of a compound I and any acid in the following and a crystal form thereof: hydrochloric acid, sulfuric acid, p-toluenesulfonic acid, benzenesulfonic acid, maleic acid, tartaric acid, oxalic acid, ethanesulfonic acid, 2-hydroxyethanesulfonic acid, camphorsulfonic acid, and 1, 5-naphthalene disulfonic acid. A free alkali crystal form of the compound I, the salt, and the crystal form of the salt have stable physical and chemical properties.
    Type: Application
    Filed: January 10, 2023
    Publication date: March 6, 2025
    Inventors: Yuan CHENG, Jun LOU, Liang WANG, Yihan ZHANG, Yongkai CHEN, Wei PENG, Chaodong WANG
  • Publication number: 20250075130
    Abstract: The provided is a novel heat-induction decoking device and method tailored for the thermal conversion of solid fuels. The efficient heat-induction decoking device for the thermal conversion of the solid fuels includes: a decoking tank body, which is configured to condense a macromolecular tar in a pyrolysis gas and discharge the condensed tar from a bottom to a tar tank for storage; an electromagnetic induction heating system, which is disposed on an outer wall surface of the decoking tank body to heat the outer wall surface of the decoking tank body; an ultrasonic vibration decoking system, which is disposed on the decoking tank body to enable the decoking tank body to generate vibration by ultrasonic wave so as to enhance tar fluidity. This innovative design not only reduces energy consumption and equipment wear but also extends system operational lifespan, thereby offering substantial improvements in economic and environmental sustainability.
    Type: Application
    Filed: November 21, 2024
    Publication date: March 6, 2025
    Applicant: SOUTHEAST UNIVERSITY
    Inventors: Huiyan ZHANG, Siyu WANG, Kai WU, Jiajun YU, Yihan WANG, Bingbing LUO
  • Patent number: 12234909
    Abstract: A hydro-mechanical series and parallel transmission device and a control method thereof are provided. The device includes an input shaft assembly, a hydraulic transmission assembly, a planetary gear transmission assembly, an intermediate gear transmission assembly, and an output shaft assembly. Switching among a hydraulic transmission mode, a mechanical transmission mode, and a hydro-mechanical composite transmission mode is implemented through combination and engagement/disengagement of clutches and brakes. The hydro-mechanical series transmission is used to expand the speed regulation range of the hydraulic transmission and is combined with the hydraulic transmission to meet the requirements on precision and the speed regulation range. The requirements of low-power and high-power operations are met through combination of the hydro-mechanical series and parallel transmissions. Multiple transmission modes are formed to adapt to the working conditions of startup, operation, and transfer.
    Type: Grant
    Filed: February 23, 2022
    Date of Patent: February 25, 2025
    Assignee: JIANGSU UNIVERSITY
    Inventors: Zhen Zhu, Yihan Zhang, Yingfeng Cai, Long Chen, Changgao Xia, Xiaodong Sun, Xiang Tian, Rui Hou, Jie Sheng
  • Patent number: 12209646
    Abstract: A hybrid transmission device with a mechanical continuously variable transmission and a control method thereof are provided. The device includes an input shaft assembly, a front planetary gear transmission assembly, a rear planetary gear transmission assembly, an output shaft, and a mechanical continuously variable transmission. Single transmission modes and hybrid transmission modes are implemented through combination and engagement/disengagement of brakes and clutches. The device and the method realize free switching among various transmission modes and integrates the single transmission modes and the hybrid transmission modes, thereby increasing the degree of freedom in adjustment and expanding the speed regulation range. Input and output shafts of a front cup wheel and ring disc transmission mechanism and a rear cup wheel and ring disc transmission mechanism are coaxial, so that the structure is compact and intermediate rollers can stably and reliably transmit large torque.
    Type: Grant
    Filed: February 23, 2022
    Date of Patent: January 28, 2025
    Assignee: JIANGSU UNIVERSITY
    Inventors: Zhen Zhu, Yihan Zhang, Yingfeng Cai, Long Chen, Xiaodong Sun, Changgao Xia, Xiang Tian, Jie Sheng, Rui Hou
  • Patent number: 12202748
    Abstract: The present disclosure relates to a desalination system of photovoltaic direct-driven membrane capacitive deionization. The system includes a photovoltaic direct-driven group and a municipal power grid-connected group. The photovoltaic direct-driven group includes a photovoltaic power collection unit, a power storage unit, a direct-driven power monitoring unit, a voltage adjustment unit, and a membrane capacitive deionization water purification unit. The municipal power grid-connected group includes a grid-connected control unit, a grid busbar unit, and an intelligent detection unit.
    Type: Grant
    Filed: August 1, 2022
    Date of Patent: January 21, 2025
    Assignees: CHANGZHOU UNIVERSITY, JIANGSU MAYMUSE ENVIRONMENTAL TECHNOLOGY CO. LTD
    Inventors: Yi Zhang, Yihan Zhang, Min Shen, Jianfeng Jiang, Shi Bu
  • Publication number: 20250020206
    Abstract: A hydro-mechanical series and parallel transmission device and a control method thereof are provided. The device includes an input shaft assembly, a hydraulic transmission assembly, a planetary gear transmission assembly, an intermediate gear transmission assembly, and an output shaft assembly. Switching among a hydraulic transmission mode, a mechanical transmission mode, and a hydro-mechanical composite transmission mode is implemented through combination and engagement/disengagement of clutches and brakes. The hydro-mechanical series transmission is used to expand the speed regulation range of the hydraulic transmission and is combined with the hydraulic transmission to meet the requirements on precision and the speed regulation range. The requirements of low-power and high-power operations are met through combination of the hydro-mechanical series and parallel transmissions. Multiple transmission modes are formed to adapt to the working conditions of startup, operation, and transfer.
    Type: Application
    Filed: February 23, 2022
    Publication date: January 16, 2025
    Applicant: JIANGSU UNIVERSITY
    Inventors: Zhen ZHU, Yihan ZHANG, Yingfeng CAI, Long CHEN, Changgao XIA, Xiaodong SUN, Xiang TIAN, Rui HOU, Jie SHENG
  • Publication number: 20240391877
    Abstract: Disclosed are a compound as an inhibitor of complement factor D, and a pharmaceutical composition thereof and the use thereof. Specifically disclosed are a compound as represented by formula (I), a tautomer thereof, a stereoisomer thereof and a prodrug thereof, or a pharmaceutically acceptable salt of any one of the above-mentioned compounds, or a solvate of any one of the above-mentioned compounds. The compound has a good inhibitory activity on complement factor D, and has an excellent pharmacokinetic and pharmacodynamic activity.
    Type: Application
    Filed: September 30, 2022
    Publication date: November 28, 2024
    Applicant: WUHAN CREATERNA SCIENCE AND TECHNOLOGY CO.,LTD.
    Inventors: Jun LOU, Jingkang WU, Li LIU, Youyou SUN, Yongkai CHEN, Yihan ZHANG, Xiaoqin LU, Feng ZHOU, Ying CHEN, Liqian ZHANG, Fan YANG, Chaodong WANG
  • Patent number: 12135073
    Abstract: A mechanical-double ring-hydraulic composite transmission mechanism includes an input member, a convergence mechanism, a hydraulic transmission mechanism, a double ring mechanism, an output member, a clutch assembly, and a brake assembly. The clutch assembly connects a left planetary gear train to a right planetary gear train. The clutch assembly connects the input member to the hydraulic transmission mechanism, the double ring mechanism, the left planetary gear train, and the right planetary gear train. The clutch assembly connects the hydraulic transmission mechanism to the right planetary gear train. The clutch assembly connects the double ring mechanism to the left planetary gear train. The clutch assembly connects the left planetary gear train and the right planetary gear train to the output member. A continuous transmission ratio between the input member and the output member is provided by adjusting a displacement ratio of the hydraulic transmission mechanism.
    Type: Grant
    Filed: February 28, 2022
    Date of Patent: November 5, 2024
    Assignee: JIANGSU UNIVERSITY
    Inventors: Qing Yu, Zhen Zhu, Rui Hou, Long Chen, Yingfeng Cai, Xiang Tian, Xiaodong Sun, Jiangyi Han, Changgao Xia, Yihan Zhang, Jie Sheng
  • Publication number: 20240317755
    Abstract: Disclosed are a heterocyclic compound, and an intermediate thereof, a preparation method therefor and the use thereof. Namely, provided are a heterocyclic compound as shown in formula I-a, and a tautomer and a pharmaceutically acceptable salt thereof, wherein the compound has a good water solubility and pharmacokinetic properties.
    Type: Application
    Filed: January 28, 2022
    Publication date: September 26, 2024
    Inventors: Jinping Li, Jun Lou, Zhanying Wang, Li Liu, Xiaodan Guo, Feng Zhou, Yihan Zhang, Yongkai Chen, Chaodong Wang
  • Publication number: 20240293420
    Abstract: Disclosed in the present invention are a pharmaceutical composition, a preparation, and a preparation method therefor and the use thereof. The pharmaceutical composition contains an active ingredient and a pharmaceutically acceptable excipient. The active ingredient contains a compound represented by formula A. The compound represented by formula A is selected from one, two or more of the crystal form I, the crystal form III and the crystal form V. The excipient is selected-from or comprises, but is not limited to, one, two or more of the following excipients: a diluent, a disintegrant, an adhesive, a glidant and a lubricant. The pharmaceutical composition and the preparation of the present invention have a good safety and/or stability, and a high P2X3 antagonistic activity, and have less effect on the taste.
    Type: Application
    Filed: June 10, 2022
    Publication date: September 5, 2024
    Inventors: Huayun Hong, Jian Hang, Jun Lou, Li Liu, Wei Wu, Yongkai Chen, Yihan Zhang, Chaodong Wang
  • Publication number: 20240288055
    Abstract: A hybrid transmission device with a mechanical continuously variable transmission and a control method thereof are provided. The device includes an input shaft assembly, a front planetary gear transmission assembly, a rear planetary gear transmission assembly, an output shaft, and a mechanical continuously variable transmission. Single transmission modes and hybrid transmission modes are implemented through combination and engagement/disengagement of brakes and clutches. The device and the method realize free switching among various transmission modes and integrates the single transmission modes and the hybrid transmission modes, thereby increasing the degree of freedom in adjustment and expanding the speed regulation range. Input and output shafts of a front cup wheel and ring disc transmission mechanism and a rear cup wheel and ring disc transmission mechanism are coaxial, so that the structure is compact and intermediate rollers can stably and reliably transmit large torque.
    Type: Application
    Filed: February 23, 2022
    Publication date: August 29, 2024
    Applicant: JIANGSU UNIVERSITY
    Inventors: Zhen ZHU, Yihan ZHANG, Yingfeng CAI, Long CHEN, Xiaodong SUN, Changgao XIA, Xiang TIAN, Jie SHENG, Rui HOU
  • Publication number: 20240280166
    Abstract: A mechanical-double ring-hydraulic composite transmission mechanism includes an input member, a convergence mechanism, a hydraulic transmission mechanism, a double ring mechanism, an output member, a clutch assembly, and a brake assembly. The clutch assembly connects a left planetary gear train to a right planetary gear train. The clutch assembly connects the input member to the hydraulic transmission mechanism, the double ring mechanism, the left planetary gear train, and the right planetary gear train. The clutch assembly connects the hydraulic transmission mechanism to the right planetary gear train. The clutch assembly connects the double ring mechanism to the left planetary gear train. The clutch assembly connects the left planetary gear train and the right planetary gear train to the output member. A continuous transmission ratio between the input member and the output member is provided by adjusting a displacement ratio of the hydraulic transmission mechanism.
    Type: Application
    Filed: February 28, 2022
    Publication date: August 22, 2024
    Applicant: JIANGSU UNIVERSITY
    Inventors: Zhen ZHU, Rui HOU, Long CHEN, Yingfeng CAI, Xiang TIAN, Xiaodong SUN, Jiangyi HAN, Changgao XIA, Yihan ZHANG, Jie SHENG
  • Publication number: 20240256738
    Abstract: Provided is an environmental sensing method based on model evolution, and the method performs a channel estimation task under the current communication system to obtain channel response data, thereby realizing environmental sensing. Firstly, an interaction mechanism between electromagnetic waves and environmental objective is divided into reflection and transmission. Subsequently, a mathematical model of channel response and environmental objective is constructed, and an environmental sensing problem is modeled as a compressed sensing optimization problem. Lastly, the present disclosure initiates from a baseline model and enables iteration and evolution of the model by solving the objective to solve the compressed sensing optimization problem, ultimately achieving environmental sensing.
    Type: Application
    Filed: April 8, 2024
    Publication date: August 1, 2024
    Inventors: Zhaoyang ZHANG, Yihan ZHANG, Xin TONG
  • Publication number: 20240239735
    Abstract: An acid addition salt of a ROCK inhibitor, and a crystal form, a composition and the pharmaceutical use thereof are provided. The acid addition salt is an acid addition salt of compound A and any one of the following acids: hydrochloric acid, p-toluenesulfonic acid, benzenesulfonic acid, maleic acid, tartaric acid, oxalic acid, fumaric acid, sulfuric acid, methanesulfonic acid, phosphoric acid, succinic acid or citric acid (A). The acid addition salt of compound A and the crystal form thereof have the characteristics of high solubility, good stability, high purity, few impurities and high bioequivalence, and are beneficial for the storage, quality control and druggability of drugs.
    Type: Application
    Filed: May 13, 2022
    Publication date: July 18, 2024
    Inventors: Liang WANG, Jun LOU, Yi YUAN, Xiaodan GUO, Yongkai CHEN, Yihan ZHANG, Huayun HONG, Wei PENG, Chaodong WANG
  • Patent number: 12019181
    Abstract: Provided is an iterative focused millimeter wave integrated communication and sensing method, which converts an environmental sensing problem into a compressed sensing reconstruction problem, and realizes the initial coarse sensing of the environment based on an approximate message passing algorithm; according to a background determining method, the present disclosure divides and determines a target object, removes the influence of background scatters on a receiving signal, and removes the background scatters repeatedly and iteratively, so as to obtain a more accurate focus sensing result of the target object.
    Type: Grant
    Filed: July 26, 2023
    Date of Patent: June 25, 2024
    Assignee: ZHEJIANG UNIVERSITY
    Inventors: Zhaoyang Zhang, Xin Tong, Yihan Zhang
  • Publication number: 20240174450
    Abstract: The present disclosure relates to the technical field of coal-fired power plant equipment, in particular to a PLC coal machine control system, including a PLC control unit, a weighing unit one, a weighing unit two, a drive unit, a frequency converter, a belt motor and a velocity measuring unit; wherein the PLC control unit is electrically connected to the weighing units one and two, for making a real-time collection of weight values of the two units; and the PLC control unit is electrically connected to the drive unit, frequency converter and velocity measuring unit, for making a real-time collection of output signals of the drive unit, velocities of the frequency converter and velocities detected by the velocity measuring unit. According to the present disclosure, the PLC controller is employed to process signals, so that the stability of the system is improved and stable operation of a generator set is guaranteed.
    Type: Application
    Filed: May 16, 2023
    Publication date: May 30, 2024
    Inventors: Jian Lan, Weiqing Li, Ziyang Guo, Chuanwei Zhang, Lijie Zhang, Rong Xiao, Qiaoxia Cai, Yihan Zhang, Yichong Chen
  • Publication number: 20240045026
    Abstract: Provided is an iterative focused millimeter wave integrated communication and sensing method, which converts an environmental sensing problem into a compressed sensing reconstruction problem, and realizes the initial coarse sensing of the environment based on an approximate message passing algorithm; according to a background determining method, the present disclosure divides and determines a target object, removes the influence of background scatters on a receiving signal, and removes the background scatters repeatedly and iteratively, so as to obtain a more accurate focus sensing result of the target object.
    Type: Application
    Filed: July 26, 2023
    Publication date: February 8, 2024
    Inventors: Zhaoyang ZHANG, Xin TONG, Yihan ZHANG
  • Publication number: 20240034729
    Abstract: Disclosed by the invention is a heterocyclic compound, an intermediate, and a preparation method therefor and an application thereof. Provided by the invention are a heterocyclic compound as shown in formula I, and a stereoisomer, a geometric isomer, a tautomer, a nitrogen oxide, a hydrate, a solvate, a metabolite, an ester, a pharmaceutically acceptable salt or a prodrug thereof. The heterocyclic compound has a high P2X3 antagonistic activity, and has good selectivity, low toxicity, good metabolic stability and little taste influence.
    Type: Application
    Filed: December 27, 2019
    Publication date: February 1, 2024
    Inventors: Jun LOU, Yongkai CHEN, Junhua LIU, Yihan ZHANG, Xiaodan GUO, Li LIU, Lina QIAN, Chaodong WANG
  • Publication number: 20240001310
    Abstract: The present disclosure discloses a preparation method of an organosilica/ceramic composite membrane with a gradient pore structure. The preparation method comprises: (1) selecting a porous ceramic material as a membrane support layer; (2) gradually replacing a solvent with water to prepare zirconium colloidal sols with different particle sizes, and successively coating the prepared zirconium colloidal sols onto a ceramic support from large to small so as to form a membrane transition layer with a gradient pore structure; and (3) catalytically synthesizing an organosilica polymeric sol using hydrochloric acid, coating the prepared organosilica sol onto the preheated transition layer through ultrasonic thermal spraying to undergo heat treatment, so as to prepare the organosilica/ceramic composite membrane with the gradient pore structure. According to the present disclosure, the transition layer with the gradient pore structure is prepared by using the zirconium colloidal sols with different particle sizes.
    Type: Application
    Filed: August 16, 2022
    Publication date: January 4, 2024
    Inventors: Jing ZHONG, Rong XU, Meng GUO, Xiuxiu REN, Yaohui WANG, Yihan ZHANG, Tiandan LU, Dongliang JIN, Ting QI
  • Publication number: 20230406850
    Abstract: Provided are a crystalline form of a compound represented by formula A, the crystalline form being crystalline form I, crystalline form II, crystalline form III, crystalline form IV, crystalline form V, crystalline form VI, crystalline form VII, crystalline form VIII or crystalline form IX, a preparation method therefor, a composition thereof, and an application thereof in the preparation of a P2X3 receptor antagonist or an application thereof in the preparation of drugs preventing and/or treating pains, urinary tract illness or respiratory system illness. The compound has high P2X3 antagonist activity, and has good selectivity, low toxicity, good metabolic stability and little taste influence.
    Type: Application
    Filed: June 24, 2021
    Publication date: December 21, 2023
    Inventors: Liang Wang, Jun Lou, Huayun Hong, Xiaodan Guo, Lina Qian, Yihan Zhang, Yongkai Chen, Chaodong Wang