Abstract: A semiconductor device, includes a channel region, and a source/drain region adjacent to the channel region. The source/drain region includes a first epitaxial layer, a second epitaxial layer epitaxially formed on the first epitaxial layer and a third epitaxial layer epitaxially formed on the second epitaxial layer, and the first epitaxial layer is made of SiAs.

Abstract: The present invention provides novel chiral bisamino-ether compounds, and method of preparation and use thereof. The chiral bisamino-ether compounds have the structure of formula (I). The method of preparation includes: using chiral aminomethanol compounds as starting materials to react with halogenated aryl compounds in the presence of a base to give a variety of chiral bisamino-ether compounds. The novel chiral bisamino-ether compounds can be used for asymmetric fluorocyclization of unsaturated heterocyclic compounds with excellent enantioselectivity and great potentials for industrial applications.

Abstract: An immunochromatographic detection device adapted for detecting an analyte in a specimen includes a surface-modified cellulose membrane, a detection unit, and a substrate. The surface-modified cellulose membrane includes opposite top and bottom surfaces, cellulose fibers, and an anti-biofouling acrylic copolymer that is bonded to the cellulose fibers. The detection unit is disposed on the top surface of the cellulose membrane, is configured to interact with the specimen, and includes a diffusion layer, a capturing layer, a detection layer, a control line layer, and an absorbent layer. The substrate is disposed on the bottom surface of the surface-modified cellulose membrane.

Abstract: A lens driving device and a driving method thereof are provided. The lens driving device includes a lens frame, a magnetic group, a driving element group and a control device. The lens frame carries at least one optical element. The magnetic group includes a plurality of pairs of magnetic elements. The driving element group includes at least two coils. The control device supplies power to the driving element group so that the lens frame is driven by the driving element group to move. The driving element group is disposed on the lens frame, and the amount of the lens frame is equal to that of the driving element group. The control device in a first driving state supplies the power to the coils in sequence so that the driving element group is moved from a pair of magnetic elements to another pair of magnetic elements.

Abstract: The present invention discloses a method for treating or preventing hereditary retinal dystrophy, the method comprising: administering a composition comprising a RIP1 inhibitor or a MLKL inhibitor to a subject in need thereof. The RIP1 inhibitor is, for example, RIPA-56, and the MLKL inhibitor is, for example, GW806742X.

Abstract: A lacosamide pharmaceutical composition as well as a preparation method and application thereof are provided. According to the lacosamide pharmaceutical composition, lacosamide or a pharmaceutically acceptable salt thereof can be dissolved out at the same time, wherein the dissolution rate of the lacosamide pharmaceutical composition is not more than 40% within 1 hour, the dissolution rate of the lacosamide pharmaceutical composition is 20-70% within 6 hours, and the dissolution rate of the lacosamide pharmaceutical composition is not less than 65% within 24 hours. The lacosamide pharmaceutical composition has good slow release performance, the tablet size can be rapidly expanded in the in-vitro dissolution process, the expanded lacosamide pharmaceutical composition has good rigidity and elasticity and has a remarkable retention effect in the stomach, and the cumulative release rate within 24 hours can reach 80% or above.

Abstract: The present invention belongs to the technical field of biomedical formulations. Provided are a temperature sensitive gel damage repair formulation and an application thereof. The formulation includes 0.01-5 mg/mL rHSA/EGF, 1.9-2.6% m/m glycine, 3.9-6.2% m/m poloxamer 188, 16.3-18.2% m/m poloxamer 407, and 0.5-100 mM phosphate buffer.

Abstract: The present disclosure related to a silicone-based foam may include a component A and a component B, where the component A may include a silicone-based matrix component, a first filler component that may include alumina trihydrate, a second filler component that may include perlite, and a third filler component that may include calcium carbonate, and where the component B may include a silicone-based matrix component, a first filler component that may include alumina trihydrate, a second filler component that may include perlite, a third filler component that may include calcium carbonate, and a fourth filler component that may include zinc borate. The silicone-based foam may have a V-0 flammability rating as measured according to ASTM D3801.

Abstract: A method produces tantalum powder. The method includes: (1) uniformly mixing a tantalum powder raw material, metal magnesium and at least one alkali metal and/or alkaline earth metal halide, loading the mixture into a container, and putting the container in a furnace; (2) raising the temperature of the furnace to 600-1200° C. in the presence of inert gas, and soaking; (3) at the end of soaking, lowering the temperature of the furnace to 600-800° C., vacuumizing the interior of the furnace to 10 Pa or less, soaking under the negative pressure so that the excessive metal is separated; (4) thereafter, raising the temperature of the furnace to 750-1200° C. in the presence of inert gas, and soaking so that the tantalum powder is sintered in the molten salt after oxygen reduction; (5) then cooling to room temperature and passivating to obtain a mixed material containing halide and tantalum powder; and (6) separating the tantalum powder from the resulting mixture.

Abstract: In one aspect, the present disclosure provides compounds which inhibit bromodomain testis (BRDT). In some embodiments, the compounds inhibit bromodomain-2 of BRDT. In another aspect, the present disclosure provides a method of inhibiting BRDT in a male subject, the method comprising administering to the male subject a therapeutically effective amount of a compound of the disclosure. In some embodiments, the method provides a contraceptive effect in the male subject.

Abstract: A tumor radiotherapy planning design method and apparatus, an electronic device, and a computer storage medium are provided, including: obtaining a current optimization parameter vector set, and calculating a current cost function value; randomly correcting the current optimization parameter vector set to generate alternative optimization parameter vector sets; then performing planning parameter optimization, and calculating corresponding total cost function values; determining current optimal or suboptimal alternative optimization parameter vector sets according to the total cost function values, sampling to update the current optimization parameter vector set and the current cost function value according to the total cost function values of the current alternative optimization parameter vector sets, and then performing an iteration repeatedly until a convergence condition is satisfied; and outputting an optimal optimization parameter vector set after the iteration, determining planning parameters, and calcu

Abstract: Disclosed is a reusable actuator for use with a drug container including a stopper comprising a container having a closed end, an open end, and a sidewall extending therebetween in a longitudinal direction, an electrode disposed inside the container for use in generating a gas, an actuating element disposed at and closing the open end of the container, the actuating element and the container defining an actuator interior, wherein the actuating element is movable relative to the container in the longitudinal direction by a gas pressure of the gas in the actuator interior, such that the actuating element applies a force to the stopper to cause a drug delivery from the drug container, and a retracting mechanism for use in removing the gas to assist the actuating element's retraction for reuse.

Abstract: A control method of a touchpad is provided. The touchpad has a determination module including a neural network. The determination module is used to determine the type of object. When the user uses the touchpad, the touchpad uses the captured object feature data of the touch object to update the determination module. Therefore, when determining the type of the touch object, the updated determination module can more accurately determine the touch object used by the user, so as to improve the determination accuracy.

Abstract: A method for forming peptide-coated nanoparticles. The nanoparticles are polylactic co-glycol polymer (PLGA). The coatings are self-assembled layers selected from RGDFFF (SEQ ID NO: 1); NGRFFF (SEQ ID NO: 2), EKHFFF (SEQ ID NO: 3) or TPP-KFF. A cargo molecule, such as a dye or a therapeutic may be bound to the nanoparticle.

Abstract: A transition method of locomotion gait of a robot includes: executing a deployment procedure multiple times, each execution includes: randomly selecting a source policy and a destination policy, simulating a transition operation from the source policy to the destination policy, and recording a transition configuration and a transition result to a transition database, where each policy is a neural network model, and a latent state in the transition configuration is a hidden layer of the neural network model of the source policy. The method further includes: training a transition-net according to the transition database, and performing the following steps by a meta-controller disposed on the robot: selecting two gait policies as an active policy and a queued policy, executing the active policy, inputting the two policies to the transition-net to obtain a success probability, and when the success probability is greater than a threshold, executing the queued policy.

Abstract: The present disclosure proposes a service plan automatic generation system and operation method thereof. The operation method includes a method for generating standardized items based on a service record, which includes the following steps: analyzing multiple instances to generate multiple feature tags, generating multiple word frequency vectors corresponding to the feature tags according to the instances, and performing an aggregation procedure for a plurality of times. Each time performing the aggregation procedure includes: executing a clustering algorithm to divide multiple instances into multiple groups, analyzing multiple variable parts and an identical part of multiple feature vectors in each group, outputting the variable parts as feature tag sets, and using the identical part as an index of the group, when a stop condition is detected, the index generated by the aggregation procedure in the last time is outputted as a standardized item.

Abstract: NFT transaction method and system relating to biological feature include: receiving, at a biological asset module of an NFT transaction system, a biological cell or tissue from a provider; obtaining, at the biological asset module, the biological feature from the biological cell or tissue; producing, at a digital asset module of the NFT transaction system, a digital creation based on the biological feature; minting, at the digital asset module, a to-be-traded NFT corresponding to the digital creation; evaluating and updating, at a transaction module of the NFT transaction system, a market price of the to-be-traded NFT based on a market condition of the biological feature; and conducting a first transaction matchmaking for the to-be-traded NFT on a virtual transaction platform based on the market price.

Abstract: Systems and methods for increasing peak ion energy with a low angular spread of ions are described. In one of the systems, multiple radio frequency (RF) generators that are coupled to an upper electrode associated with a plasma chamber are operated in two different states, such as two different frequency levels, for pulsing of the RF generators. The pulsing of the RF generators facilitates a transfer of ion energy during one of the states to another one of the states for increasing ion energy during the other state to further increase a rate of processing a substrate.

Abstract: A breathable and waterproof non-woven fabric is manufactured by a manufacturing method including the following steps. Performing a kneading process on 87 to 91 parts by weight of a polyester, 5 to 7 parts by weight of a water repellent, and 3 to 6 parts by weight of a flow promoter to form a mixture, in which the polyester has a melt index between 350 g/10 min and 1310 g/10 min at a temperature of 270° C., and the mixture has a melt index between 530 g/10 min and 1540 g/10 min at a temperature of 270° C. Performing a melt-blowing process on the mixture, such that the flow promoter is volatilized and a melt-blown fiber is formed, in which the melt-blown fiber has a fiber body and the water repellent disposed on the fiber body with a particle size (D90) between 350 nm and 450 nm.

Abstract: In an image optimization method, an image generation network, a to-be-optimized image, and a plurality of preset image features are obtained. A target feature is selected from the plurality of preset image features based on (i) the target feature and the to-be-optimized image and (ii) a preset similarity condition. The target feature and an initial offset parameter are input to the image generation network. The initial offset parameter is adjusted according to a difference between an output of the image generation network and the to-be-optimized image, to obtain a target offset parameter. The target feature and the target offset parameter are input to the image generation network, to generate an optimized image. Apparatus and non-transitory computer-readable storage medium counterpart embodiments are also contemplated.