Abstract: Large scale processes for producing high purity samples of biologically active molecules of interest from bacterial cells are disclosed. The methods comprise the steps of producing a lysate solution by contacting a cell suspension of said plurality of cells with lysis solution; neutralizing said lysate solution with a neutralizing solution to produce a dispersion that comprises neutralized lysate solution and debris; filtering the dispersion through at least one filter; performing ion exchange separation on said neutralized lysate solution to produce an ion exchange eluate; and performing hydrophobic interaction separation on said ion exchange eluate to produce a hydrophobic interaction solution. Further, provided are compositions comprising large scale amounts of plasmid DNA produced by the disclosed large scale processes.

Abstract: Articles and methods regarding the making and use of low-shedding nonwoven abrasive articles, such as abrasive wheels and hand pads, that have a low shed rate and achieve a high grind ratio. The abrasive articles comprise a blend of a plurality of primary abrasive particles and a plurality of reinforcing abrasive particles that is disposed on a nonwoven web substrate. The primary abrasive particles have an average particle size equal to or larger than the average fiber diameter of the substrate fibers, and the reinforcing abrasive particles have an average particle size smaller than the average fiber diameter.

Abstract: The invention belongs to the technical field of medicines. In particular, the invention relates to use of (benzenesulfonamido) benzamide compounds for inhibiting liver fibrosis, or preventing and/or treating a liver injury, or improving a liver function, or preventing and/or treating a liver disease associated with liver fibrosis, for modulating (e.g. reducing) the content of collagen (e.g. type I collagen) in liver tissue, for modulating (e.g. inhibiting) the activity of COL1A1 promoter in a cell, and for modulating (e.g. inhibiting) expression level of a gene associated with liver fibrosis in a cell.

Abstract: The present disclosure relates to abrasive buffing articles (“abrasive buffs”) and methods of making the same. The abrasive buffs include a substrate, such as a fabric, that has been impregnated with an abrasive polymeric composition that includes abrasive particles, such as primary abrasive particles and/or abrasive aggregates, such as spray dried abrasive aggregates. The abrasive buffs are flexible and capable of conforming to and effectively abrading, polishing, and buffing workpieces possessing a complex geometry.

Abstract: The invention belongs to the technical field of medicines. In particular, the invention relates to use of (benzenesulfonamido) benzamide compounds for inhibiting liver fibrosis, or preventing and/or treating a liver injury, or improving a liver function, or preventing and/or treating a liver disease associated with liver fibrosis, for modulating (e.g. reducing) the content of collagen (e.g. type I collagen) in liver tissue, for modulating (e.g. inhibiting) the activity of COL1A1 promoter in a cell, and for modulating (e.g. inhibiting) expression level of a gene associated with liver fibrosis in a cell.

Abstract: The present disclosure relates to abrasive buffing articles (“abrasive buffs”) and methods of making the same. The abrasive buffs include a substrate, such as a fabric, that has been impregnated with an abrasive polymeric composition that includes abrasive particles, such as primary abrasive particles and/or abrasive aggregates, such as spray dried abrasive aggregates. The abrasive buffs are flexible and capable of conforming to and effectively abrading, polishing, and buffing workpieces possessing a complex geometry.

Abstract: In a wireless network including a first cell and a second cell, it is determined whether a measure of mobility of a user device meets a mobility criterion, and it is determined whether a size of the second cell meets a cell size criterion. When it is determined that (i) the measure of mobility of the user device meets the mobility criterion and (ii) the size of the second cell meets the cell size criterion, the user device is prevented from being switched from the first cell to the second cell, or at least one of (i) a handover parameter or (ii) a cell reselection parameter is adjusted in order to change a probability that the user device will switch from the first cell to the second cell.

Abstract: A non-volatile memory module includes a volatile memory circuit; an interface to a reference voltage source external to the module providing an external reference voltage to the volatile memory circuit by which the volatile memory circuit and external devices may communicate reliably at high speeds; an internal reference voltage generator; and a control circuit adapted to cause the volatile memory circuit to be decoupled from using the external reference voltage and coupled to using a reference voltage from the internal reference voltage generator upon the non-volatile memory module ceasing to draw power from an external power source.

Abstract: A wireless communication device first and second transceivers to transmit in respective first and second frequency bands. The device includes an arbiter to map the first frequency band into a plurality of regions and sub-regions and map a plurality of channels to the sub-regions, and a first controller to select one of the plurality of sub-regions and inform the arbiter of the selected one of the plurality of sub-regions. The arbiter is further to select a first group of channels in the second frequency band when the selected one of the plurality of sub-regions is a first sub-region, select a second group of channels in the second frequency band when the selected one of the plurality of sub-regions is a second sub-region, and select a third group of channels in the second frequency band when the selected one of the plurality of sub-regions is a third sub-region.

Abstract: A method for using a location-based service while preserving anonymity includes receiving a location associated with a mobile node, receiving an anonymity level associated with the mobile node, computing a region containing the location of the mobile node and a number of footprints based on the anonymity level, wherein each of the footprints from a different user, and providing the region to a location-based service to thereby preserve anonymity of the mobile node. A method also allow a mobile device or its user to specify the anonymity level by selecting a public region consistent with a user's feelings towards desired privacy.

Abstract: A device including a transmitter, a receiver and an arbiter. The transmitter transmits a first signal. The first signal has a fundamental frequency in a first frequency band of a first wireless protocol. The receiver receives a second signal. The second signal has a fundamental frequency in a second frequency band of a second wireless protocol. The first frequency band is adjacent to or at least partially overlaps the second frequency band. The arbiter allows the transmitter to transmit the first signal in the first frequency band while the receiver receives the second signal in the second frequency band. The arbiter also, if a power level of the first signal is less than a first threshold, changes: a modulation and coding scheme of the transmitter for the first signal; a modulation and coding scheme of the receiver for the second signal; or a multiple input and multiple output rank.

Abstract: A circuit includes a series arrangement of capacitors and a balancing circuit coupled to the series arrangement of capacitors, the balancing circuit having drive circuits each coupled at a node in the series arrangement at which two of the capacitors are coupled in series. The drive circuit includes an output stage having switches arranged to either push or pull current from a drive circuit output depending on the state of the switches.

Abstract: A method for using a location-based service while preserving anonymity includes receiving a location associated with a mobile node, receiving an anonymity level associated with the mobile node, computing a region containing the location of the mobile node and a number of footprints based on the anonymity level, wherein each of the footprints from a different user, and providing the region to a location-based service to thereby preserve anonymity of the mobile node. A method also allow a mobile device or its user to specify the anonymity level by selecting a public region consistent with a user's feelings towards desired privacy.

Abstract: A wireless communication device first and second transceivers to transmit in respective first and second frequency bands. The device includes an arbiter to map the first frequency band into a plurality of regions and sub-regions and map a plurality of channels to the sub-regions, and a first controller to select one of the plurality of sub-regions and inform the arbiter of the selected one of the plurality of sub-regions. The arbiter is further to select a first group of channels in the second frequency band when the selected one of the plurality of sub-regions is a first sub-region, select a second group of channels in the second frequency band when the selected one of the plurality of sub-regions is a second sub-region, and select a third group of channels in the second frequency band when the selected one of the plurality of sub-regions is a third sub-region.

Abstract: In a wireless network including a first cell and a second cell, it is determined whether a measure of mobility of a user device meets a mobility criterion, and it is determined whether a size of the second cell meets a cell size criterion. When it is determined that (i) the measure of mobility of the user device meets the mobility criterion and (ii) the size of the second cell meets the cell size criterion, the user device is prevented from being switched from the first cell to the second cell, or at least one of (i) a handover parameter or (ii) a cell reselection parameter is adjusted in order to change a probability that the user device will switch from the first cell to the second cell.

Abstract: 3D mesh models are represented by three types of data: connectivity data, geometry data and property data. The surface of a 3D object is a triangle mesh. 3D meshes contain huge amounts of data that need to be compressed efficiently. Additionally to the common world coordinate system for the complete model and local coordinate system for a single triangle, an individual component coordinate system for each connected component is used. The component coordinate system is used to normalize the orientation of the respective component for quantization and de-quantization. This improves the accuracy of encoded 3D mesh models after quantization/de-quantization, particularly if a 3D mesh model comprises one or more distinct components.

Abstract: Apparatus having corresponding methods and computer-readable media comprise: a transmitter configured to transmit, according to a first protocol, first wireless signals in a first frequency band; and a receiver configured to receive, according to a second protocol, second wireless signals in a second frequency band, wherein the second frequency band is adjacent to or overlaps the first frequency band; and an arbiter configured to allow the transmitter to transmit the first wireless signals according to the first protocol while the receiver receives the second wireless signals according to the second protocol responsive to at least one of i) a signal power level of the first wireless signals being less than a first signal power threshold; and ii) a signal power level of the second wireless signals being greater than a second signal power threshold.

Abstract: A method for using a location-based service while preserving anonymity includes receiving a location associated with a mobile node, receiving an anonymity level associated with the mobile node, computing a region containing the location of the mobile node and a number of footprints based on the anonymity level, wherein each of the footprints from a different user, and providing the region to a location-based service to thereby preserve anonymity of the mobile node. A method also allow a mobile device or its user to specify the anonymity level by selecting a public region consistent with a user's feelings towards desired privacy.

Abstract: A method for encoding vertex orientations, also known as normal components, of a 3D mesh model comprises a first clustering of the normal components, determining for each of the first clusters a sphere sector to which most of its elements belong, mapping normal components to a predefined sector, re-clustering the normal components in the predefined sector into second clusters, determining predictors for the second clusters and encoding a normal component by its residual, a reference to its predictor and data indicating which of said mirror mapping operations were performed. A sphere sector is obtained by dividing a sphere into m equal spherical segments and dividing each of said spherical segments into n equal sectors. The first clustering for the sector mapping and the second clustering for predictive coding result in an improved compression ratio.

Abstract: Apparatus having corresponding methods and computer-readable media comprise: a first transceiver comprising a controller configured to select one of a plurality of frequency regions, wherein bandwidths of the frequency regions are non-uniform, and wherein the first transceiver is configured to transceive, according to a first protocol, first wireless signals in the one of the plurality of frequency regions selected by the controller; an arbiter configured to select one or more frequency channels based on the one of the plurality of the frequency regions selected by the controller; and a second transceiver configured to transceive, according to a second protocol, second wireless signals only in the one or more frequency channels selected by the arbiter.