Patents by Inventor Ying-Cheng Lo
Ying-Cheng Lo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200113781Abstract: A sterile solution product bag includes sterilization grade filter integrated directly into the product bag such that microbial and particulate matter filtration can be performed using the filter directly at the point of fill. The filter can include a hollow fiber filter membrane contained in a stem connected to a bladder of the product bag.Type: ApplicationFiled: December 11, 2019Publication date: April 16, 2020Inventors: Grant Anthony Bomgaars, Bernd Krause, Mark Edward Pasmore, Michael Joseph Sadowski, Yuanpang Samuel Ding, Ying-Cheng Lo, Joseph Vincent Ranalletta
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Patent number: 10617603Abstract: A sterile solution product bag includes sterilization grade filter integrated directly into the product bag such that microbial and particulate matter filtration can be performed using the filter directly at the point of fill. The filter can include a hollow fiber filter membrane contained in a stem connected to a bladder of the product bag.Type: GrantFiled: January 20, 2017Date of Patent: April 14, 2020Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Grant Anthony Bomgaars, Bernd Krause, Mark Edward Pasmore, Michael Joseph Sadowski, Yuanpang Samuel Ding, Ying-Cheng Lo, Joseph Vincent Ranalletta
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Publication number: 20200046890Abstract: A handheld personal communication apparatus for dialysis includes a reader to (i) read a marking displayed on a dialysis fluid container to acquire data concerning at least one of a dialysis fluid type or a dialysis fluid volume from the marking, and/or (ii) receive a patient weight signal from a weight scale; a processor using at least one of the dialysis fluid type, dialysis fluid volume, or patient weight to determine a dialysis dwell time for at least one cycle of a dialysis therapy, the dialysis dwell time being a time to achieve, over the at least one cycle, at least one of (a) a specified ultrafiltrate level, (b) a urea removal level, or (c) a creatinine removal level; and an output interface providing an indication to the patient of a completion of the dialysis dwell time.Type: ApplicationFiled: October 21, 2019Publication date: February 13, 2020Inventors: Bijan Elahi, Ying-Cheng Lo, Vikram Prabhakar Mehendale
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Publication number: 20190388611Abstract: An infusion device for dispensing fluid at a predetermined flow rate includes an elastic bladder, a pressure regulator, and a flow restrictor. The elastic bladder includes a bladder volume portion and a bladder outlet, and the elastic bladder stores fluid in the bladder volume portion and dispenses fluid through the outlet at a bladder pressure. The pressure regulator is in fluid communication with the outlet of the elastic bladder. The pressure regulator includes a fluid inlet and a fluid outlet. The fluid inlet is coupled to the bladder outlet to receive fluid from the bladder. The flow restrictor is in fluid communication with the fluid outlet. The flow restrictor and the pressure regulator cooperate to discharge fluid from the flow restrictor at a predetermined flow rate.Type: ApplicationFiled: June 20, 2018Publication date: December 26, 2019Inventors: Dustin Christopher Cawthon, Ieng Kin Lao, Thomas Edward Dudar, Yuanpang Samuel Ding, Ying-Cheng Lo, Houzhi Luo, Michael Patrick Morrissey, Jeffrey Scott Packard
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Publication number: 20190351121Abstract: A renal failure blood therapy system includes a renal failure blood therapy machine, concentration levels for each of a plurality of solutes removed from a patient's blood at each of the multiple times, a display device configured to display for selection at least one removed blood solute from the plurality of removed blood solutes, and a device programmed to (i) estimate at least one renal failure blood therapy patient parameter using the determined concentration levels for the at least one selected removed blood solute, (ii) determine a plurality of acceptable renal failure blood therapy treatments that meet a predetermined removed blood solute clearance for the at least one selected removed blood solute using the at least one renal failure blood therapy patient parameter, and (iii) enable selection of at least one of the plurality of acceptable renal failure blood therapy treatments for operation at the renal failure blood therapy machine.Type: ApplicationFiled: July 29, 2019Publication date: November 21, 2019Inventors: Alp Akonur, John Kenneth Leypoldt, Ying-Cheng Lo, Baris Ugur Agar
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Patent number: 10449284Abstract: A handheld personal communication apparatus for dialysis includes: a reader to (i) read a marking displayed on a dialysis fluid container to acquire data concerning at least one of a dialysis fluid type or a dialysis fluid volume from the marking, and/or (ii) receive a patient weight signal from a weight scale; a processor using at least one of the dialysis fluid type, dialysis fluid volume, or patient weight to determine a dialysis dwell time for at least one cycle of a dialysis therapy, the dialysis dwell time being a time to achieve, over the at least one cycle, at least one of (a) a specified ultrafiltrate level, (b) a urea removal level, or (c) a creatinine removal level; and an output interface providing an indication to the patient of a completion of the dialysis dwell time.Type: GrantFiled: April 27, 2015Date of Patent: October 22, 2019Assignees: Baxter Interntional Inc., Baxter Healthcare SAInventors: Bijan Elahi, Ying-Cheng Lo, Vikram Prabhakar Mehendale
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Publication number: 20190307939Abstract: A gravity fed peritoneal dialysis (“PD”) machine includes: a frame configured to be set on a supporting surface; at least one load cell; a scale platform supported by the frame via the at least one load cell positioned between the frame and the scale platform; a drain container support in mechanical communication with and extending downwardly from the scale platform, the machine configured such that when the frame is set on the supporting surface, at least one fresh PD fluid supply container is supportable by the scale platform above the at least one load cell and at least one used PD fluid drain container is supportable by the drain container support below the at least one load cell, so that a combined weight of fresh PD fluid and used PD fluid may be sensed by the at least one load cell.Type: ApplicationFiled: April 5, 2018Publication date: October 10, 2019Inventors: Ying-Cheng Lo, Aaron W. Brown, Yuanpang Samuel Ding, Alex Lao, Zachariah Louis Fuller, Aaron Joseph Geier, Alan John Harvey, Leansu Kiatoukaysy Lo
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Publication number: 20190262527Abstract: Dialysis is enhanced by using nanoclay sorbents to better absorb body wastes in a flow-through system. The nanoclay sorbents, using montmorillonite, bentonite, and other clays, absorb significantly more ammonium, phosphate, and creatinine, and the like, than conventional sorbents. The montmorillonite, the bentonite, and the other clays may be used in wearable systems, in which a dialysis fluid is circulated through a filter with the nanoclay sorbents. Waste products are absorbed by the montmorillonite, the bentonite, and the other clays and the dialysis fluid is recycled to a patient's peritoneum. Using an ion-exchange capability of the montmorillonite, the bentonite, and the other clays, waste ions in the dialysis fluid are replaced with desirable ions, such as calcium, magnesium, and bicarbonate. The nanoclay sorbents are also useful for refreshing a dialysis fluid used in hemodialysis and thus reducing a quantity of the dialysis fluid needed for the hemodialysis.Type: ApplicationFiled: May 15, 2019Publication date: August 29, 2019Inventors: Rosa H. Yeh, Wei Xie, Hsinjin E. Yang, Michael T.K. Ling, Ying-Cheng Lo
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Patent number: 10363351Abstract: A renal failure blood therapy system includes a renal failure blood therapy machine, concentration levels for each of a plurality of solutes removed from a patient's blood at each of the multiple times, a display device configured to display for selection at least one removed blood solute from the plurality of removed blood solutes, and a device programmed to (i) estimate at least one renal failure blood therapy patient parameter using the determined concentration levels for the at least one selected removed blood solute, (ii) determine a plurality of acceptable renal failure blood therapy treatments that meet a predetermined removed blood solute clearance for the at least one selected removed blood solute using the at least one renal failure blood therapy patient parameter, and (iii) enable selection of at least one of the plurality of acceptable renal failure blood therapy treatments for operation at the renal failure blood therapy machine.Type: GrantFiled: March 9, 2017Date of Patent: July 30, 2019Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Alp Akonur, John Kenneth Leypoldt, Ying-Cheng Lo, Baris Ugur Agar
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Patent number: 10342912Abstract: Dialysis is enhanced by using nanoclay sorbents to better absorb body wastes in a flow-through system. The nanoclay sorbents, using montmorillonite, bentonite, and other clays, absorb significantly more ammonium, phosphate, and creatinine, and the like, than conventional sorbents. The montmorillonite, the bentonite, and the other clays may be used in wearable systems, in which a dialysis fluid is circulated through a filter with the nanoclay sorbents. Waste products are absorbed by the montmorillonite, the bentonite, and the other clays and the dialysis fluid is recycled to a patient's peritoneum. Using an ion-exchange capability of the montmorillonite, the bentonite, and the other clays, waste ions in the dialysis fluid are replaced with desirable ions, such as calcium, magnesium, and bicarbonate. The nanoclay sorbents are also useful for refreshing a dialysis fluid used in hemodialysis and thus reducing a quantity of the dialysis fluid needed for the hemodialysis.Type: GrantFiled: November 17, 2017Date of Patent: July 9, 2019Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Rosa H. Yeh, Wei Xie, Hsinjin E. Yang, Michael T. K. Ling, Ying-Cheng Lo
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Publication number: 20190046712Abstract: A hemodiafiltration system with a disposable pumping unit is disclosed. An example system includes a medical fluid pump actuator, a medical fluid heater, a blood filter and a disposable unit. The example disposable unit includes a medical fluid cassette portion including a medical fluid cassette housing configured to be operatively connected to the medical fluid pump actuator to pump medical fluid through the medical fluid cassette portion when the medical fluid cassette portion is in fluid communication with a medical fluid source. The example medical fluid cassette portion is also configured to be placed in fluid communication with the blood filter and with an extracorporeal circuit communicating with the blood filter, the fluid communication enabling hemodiafiltration to be performed. The example disposable unit also includes a heater bag configured to be placed in operable communication with the medical fluid heater and in fluid communication with the medical fluid cassette portion.Type: ApplicationFiled: October 15, 2018Publication date: February 14, 2019Inventors: Ying-Cheng Lo, Robert W. Childers, Thomas D. Kelly, Justin Rohde
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Publication number: 20190021947Abstract: A sterile solution product bag includes sterilization grade filter integrated directly into the product bag such that microbial and particulate matter filtration can be performed using the filter directly at the point of fill. The filter can include a hollow fiber filter membrane contained in a stem connected to a bladder of the product bag.Type: ApplicationFiled: January 20, 2017Publication date: January 24, 2019Inventors: Grant Anthony Bomgaars, Bernd Krause, Mark Edward Pasmore, Michael Joseph Sadowski, Yuanpang Samuel Ding, Ying-Cheng Lo, Joseph Vincent
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Publication number: 20190002136Abstract: A method of providing filled product bags of sterile and particulate-free fluid includes securing a product bag to one of a plurality of movable cradles, wherein the product bag has a bladder, a stem fluidly connected to an opening of the bladder, and a filter disposed in-line with the stem. After securing the bag, an inlet of the stem is connected to an outlet of a nozzle assembly and at least partially filling the product bag with a fluid through a nozzle of the nozzle assembly to create a filled product bag, wherein filling the product bag includes passing the fluid through the filter and into the bladder. After filling, the stem of the filled product bag is sealed at a location below the filter. The stem is cut at a location above the seal and below the filter.Type: ApplicationFiled: January 20, 2017Publication date: January 3, 2019Inventors: Grant Anthony Bomgaars, Joseph Vincent Ranalletta, Yuanpang Samuel Ding, Ying-Cheng Lo, Mark Edward Pasmore, Michael Joseph Sadowski, Anastasios Hristakos, Thomas Edward Dudar, Bernd Krause
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Patent number: 10155080Abstract: A renal therapy system with cassette-based blood and dialysate pumping is disclosed. An example system includes a blood pump actuator, a dialysis fluid pump actuator, a dialysis fluid heater, a dialyzer, and a disposable unit. The example disposable unit includes a blood cassette portion configured to be operatively connected to the blood pump actuator to pump blood through the blood cassette portion. The example disposable unit also includes a dialysis fluid cassette portion, separate from the blood cassette portion, configured to be operatively connected to the dialysis fluid pump actuator to pump dialysis fluid through the dialysis fluid cassette portion. The blood cassette portion and the dialysis fluid cassette portion are both in fluid communication with the dialyzer. The example disposable unit also includes a heater bag configured to be placed in operable communication with the dialysis fluid heater and in fluid communication with the dialysis fluid cassette portion.Type: GrantFiled: February 5, 2018Date of Patent: December 18, 2018Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Ying-Cheng Lo, Robert W. Childers, Thomas D. Kelly, Justin Rohde
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Publication number: 20180221555Abstract: A system for monitoring water quality for dialysis, dialysis fluids, and body fluids treated by dialysis fluids, is disclosed. The system uses microelectromechanical systems (MEMS) sensors for detecting impurities in input water or dialysis fluid, and in the prepared dialysate. These sensors may also be used to monitor and check the blood of the patient being treated. These sensors include ion-selective sensors, for ions such as ammonium or calcium, and also include amperometric array sensors, suitable for ions from chlorine or chloramines, e.g., chloride. These sensors assist in the monitoring of water supplies from a city water main or well. The sensors may be used in conjunction with systems for preparing dialysate solutions from water for use at home or elsewhere.Type: ApplicationFiled: March 30, 2018Publication date: August 9, 2018Inventors: Justin B. Rohde, William Wenli Han, Elizabeth A. Everitt, Michael Edward Hogard, Ying-Cheng Lo, Erin Michele Copeland, William Patrick Burns
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Publication number: 20180221557Abstract: A system for performing a peritoneal dialysis therapy includes at least one dialysis fluid pump, and a logic implementer operable with the at least one dialysis fluid pump to perform a plurality of peritoneal dialysis cycles, the cycles including a fill phase, a dwell phase and a drain phase, the logic implementer configured to: (i) store a first peritoneal dialysis treatment having a total prescribed fresh dialysis fluid fill volume delivered over a number of cycles; and (ii) convert the first peritoneal dialysis treatment into a second peritoneal dialysis treatment having a different number of cycles and using the same total prescribed fresh dialysis fluid fill volume.Type: ApplicationFiled: April 4, 2018Publication date: August 9, 2018Inventors: Robert W. Childers, Ying-Cheng Lo, Peter A. Hopping
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Publication number: 20180169316Abstract: A renal therapy system with cassette-based blood and dialysate pumping is disclosed. An example system includes a blood pump actuator, a dialysis fluid pump actuator, a dialysis fluid heater, a dialyzer, and a disposable unit. The example disposable unit includes a blood cassette portion configured to be operatively connected to the blood pump actuator to pump blood through the blood cassette portion. The example disposable unit also includes a dialysis fluid cassette portion, separate from the blood cassette portion, configured to be operatively connected to the dialysis fluid pump actuator to pump dialysis fluid through the dialysis fluid cassette portion. The blood cassette portion and the dialysis fluid cassette portion are both in fluid communication with the dialyzer. The example disposable unit also includes a heater bag configured to be placed in operable communication with the dialysis fluid heater and in fluid communication with the dialysis fluid cassette portion.Type: ApplicationFiled: February 5, 2018Publication date: June 21, 2018Inventors: Ying-Cheng Lo, Robert W. Childers, Thomas D. Kelly, Justin Rohde
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Patent number: 9943632Abstract: A system for performing a peritoneal dialysis therapy includes at least one dialysis fluid pump, and a control unit operable with the at least one dialysis fluid pump to perform a plurality of peritoneal dialysis cycles, the cycles including a fill phase, a dwell phase and a drain phase. The control unit configured to (i) store a previously entered continuous cycling peritoneal dialysis (“CCPD”) therapy having a total prescribed fresh dialysate fill volume delivered over n cycles, the cycles performed over a total therapy duration, and (ii) automatically convert the CCPD therapy into a tidal peritoneal dialysis therapy having n+1 cycles, less a number of cycles already completed during the CCPD therapy, using the total prescribed fresh dialysis fill volume, and maintaining the total therapy duration.Type: GrantFiled: September 15, 2015Date of Patent: April 17, 2018Assignees: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE SAInventors: Robert W. Childers, Ying-Cheng Lo, Peter A. Hopping
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Patent number: 9931454Abstract: A medical fluid or dialysis system includes an auto-connection mechanism that connects connectors from the supply bags to dialysis cassette ports or cassette supply lines. The system provides for multiple, e.g., four, supply bags, which can be connected to a manifold of the auto-connection mechanism. Tip protecting caps that protect the supply line ends and cassette ports or cassette supply line ends are made to be compatible with the auto-connection mechanism. The auto-connection mechanism removes all the caps and connects the supply lines to the cassette. At least one roller occluder is provided that occludes the supply tubing prior to the tip protecting caps being removed. The roller occludes prevent medical dialysis fluid from spilling out of the supply lines between the time that the caps are removed and connection to the cassette is made.Type: GrantFiled: May 1, 2015Date of Patent: April 3, 2018Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Ying-Cheng Lo, Yuanpang Samuel Ding
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Publication number: 20180071446Abstract: Dialysis is enhanced by using nanoclay sorbents to better absorb body wastes in a flow-through system. The nanoclay sorbents, using montmorillonite, bentonite, and other clays, absorb significantly more ammonium, phosphate, and creatinine, and the like, than conventional sorbents. The montmorillonite, the bentonite, and the other clays may be used in wearable systems, in which a dialysis fluid is circulated through a filter with the nanoclay sorbents. Waste products are absorbed by the montmorillonite, the bentonite, and the other clays and the dialysis fluid is recycled to a patient's peritoneum. Using an ion-exchange capability of the montmorillonite, the bentonite, and the other clays, waste ions in the dialysis fluid are replaced with desirable ions, such as calcium, magnesium, and bicarbonate. The nanoclay sorbents are also useful for refreshing a dialysis fluid used in hemodialysis and thus reducing a quantity of the dialysis fluid needed for the hemodialysis.Type: ApplicationFiled: November 17, 2017Publication date: March 15, 2018Inventors: Rosa H. Yeh, Wei Xie, Hsinjin E. Yang, Michael T.K. Ling, Ying-Cheng Lo