Abstract: A display substrate includes an underlayer substrate and a circuit structure layer. The circuit structure layer is located in a display area of the underlayer substrate. The circuit structure layer includes at least one first circuit area and at least one second circuit area. The first circuit area includes at least one first gate drive circuit; the second circuit area includes at least one second gate drive circuit. The first gate drive circuit is cascaded with the second gate drive circuit. The first gate drive circuit includes a plurality of cascaded first gate drive units, and the second gate drive circuit includes a plurality of cascaded second gate drive units. A plurality of first gate drive units are sequentially arranged in a second direction, and a plurality of second gate drive units are sequentially arranged in the second direction.

Abstract: In an approach for post-modeling data visualization and analysis, a processor presents a first visualization of a training dataset in a first plot. Responsive to receiving a selection of a data group of the training dataset to analyze, a processor identifies three or fewer key model features of the data group of the training dataset. A processor ascertains a representative record of each key model feature of the three or fewer key model features using a Local Interpretable Model-Agnostic Explanation technique. A processor presents a second visualization of the three or fewer key model features and the representative record of each key model feature in a second plot.

Abstract: An engineered type V Cas protein is provided, including a parental type V Cas protein and an HNH domain. The HNH domain is located at an N-terminus of the parental type V Cas protein; or the HNH domain is located between two continuous or non-continuous amino acids of the parental type V Cas protein, named as a first amino acid and a second amino acid, respectively. The first amino acid and the second amino acid are selected from one of amino acids 1 to 10 at the N-terminus of the parental type V Cas protein, and the first amino acid and the second amino acid are different amino acid positions of the parental type V Cas protein; or the first amino acid and the second amino acid are selected from amino acid positions corresponding to amino acids 794 and 795 of SEQ ID NO: 9.

Abstract: Example methods and systems provide a workplace assistant application that can detect one or more received messages associated with a remote user and access multiple communication channels connected to a workplace assistant client application. Received message(s), information from the channels, and stored metadata can be submitted to one or more predictive models to provide a context for the message(s). The system can generate, using output from the predictive model(s), a response message based at least in part on the context of the received message. The system can display the response in the workplace assistant client application for acceptance or editing by the user, or transmit the response message.

Abstract: Determining whether synthetic data is sufficient for utilization in connection with one or more machine learning models. The computing device accesses a protected batch of data associated with a machine learning model. The computing device accesses a simulated batch of data, the simulated batch of data based upon but anonymizing the protected batch of data. The computing device accesses one or more comparisons of one or more variables in the protected batch of data and the simulated batch of data to obtain a similarity value. The computing device performs a machine learning function utilizing at least in-part the simulated batch of data if the similarity value exceeds a similarity threshold.

Abstract: Example methods and systems provide a workplace assistant application that can detect electronic content associated with a remote user and access multiple communication channels connected to a workplace assistant client application. The system can submit the electronic content to one or more predictive models to provide a context for the electronic content. The context is based at least in part on information from multiple channels. The system can generate, using the predictive model(s), an action item based at least in part on the context of the electronic content as well as display or store the action item using the workplace assistant client application. An action item, as examples, can be a “to do” item, a meeting agenda, a reminder, a meeting, a task, or some combination of one or more of these.

Abstract: A display panel includes: a substrate, sub-pixels and a gate drive circuit. The sub-pixel includes a pixel drive circuit. The gate drive circuit includes cascaded shift registers, and a shift register is electrically connected to pixel drive circuits in a row of sub-pixels. The gate drive circuit further includes cascade input signal lines and cascade display reset signal lines. The cascade input signal line is configured to connect a shift signal terminal and an input signal terminal of two different shift register; and the cascade display reset signal line is configured to connect a shift signal terminal and a display reset signal terminal of two different shift register. The display panel has sub-pixel regions for arranging the sub-pixels and first gap regions each located between two adjacent columns of sub-pixel regions; the cascade display reset signal lines and the cascade input signal lines are disposed in different first gap regions.

Abstract: An embodiment configures a plurality of parameters, the parameters being usable to generate artificial data from original data, the configuring adjusting a level of privacy in the artificial data. An embodiment fits a distribution type to a variable of the original data. An embodiment adjusts, using a desired level of privacy and the distribution type, a level of noise, wherein the level of noise corresponds to the desired level of privacy. An embodiment generates, using the distribution type and the level of noise, the artificial data, the artificial data achieving the desired level of privacy by including noise data corresponding to the level of noise.

Abstract: Disclosed are compounds of Formula (I): or a pharmaceutically acceptable salt, a tautomer, a stereoisomer, or a deuterated analog thereof, wherein R2, R3, R4, Y1, Y2, X, and Z are as described in any of the embodiments described in this disclosure; compositions thereof; and uses thereof.

Abstract: Provided is a comprehensive quantitative evaluation method and system for welding usability of welding consumables.

Abstract: A computer-implemented method for anomaly detection for a time series data is provided. Aspects include receiving a time series data including a plurality of sequential data points, calculating an expected next value for the time series data based on the plurality of sequential data points, and receiving an actual next value corresponding to the time series data. Aspects also include calculating an anomaly strength estimate based on the expected next value and the actual next value, identifying one of a plurality of anomaly detection pipelines based on the anomaly strength estimate and a portrait associated with each of the plurality of anomaly detection pipelines, and obtaining an anomaly prediction by inputting the time series data and the actual next value into the one of the plurality of anomaly detection pipelines.

Abstract: The present disclosure provides a circuitry structure and a display substrate. The circuitry structure includes a base substrate, and a functional transistor and a signal transmission line arranged on the base substrate. The functional transistor includes a first conductive connection member, a first electrode, a second electrode, at least two gate electrode patterns and at least one active pattern. Orthogonal projections of the first electrode, the second electrode and the at least two gate electrode patterns onto the base substrate at least partially overlap with an orthogonal projection of the active pattern onto the base substrate, and first ends of the gate electrode patterns are coupled to each other. The first conductive connection member is arranged at a layer different from the gate electrode pattern, and coupled to second ends of the gate electrode patterns. The signal transmission line is coupled to the first conductive connection member.

Abstract: An antibody or an antigen-binding fragment thereof that binds to CD228, and an antibody-drug conjugate containing the antibody or antigen-binding fragment thereof. The antibody or antigen-binding fragment thereof has a high affinity to a CD228 protein and an ability to mediate ADCC. The antibody-drug conjugate exhibits an inhibitory effect on various tumors. A nucleic acid encoding the antibody or antigen-binding fragment thereof; a cell containing the nucleic acid; a pharmaceutical composition containing the antibody or antigen-binding fragment thereof, the nucleic acid, the cell or the antibody-drug conjugate; and a kit. The use of the antibody or antigen-binding fragment thereof, the nucleic acid, the antibody-drug conjugate or the pharmaceutical composition in the prevention, treatment, detection or diagnosis of diseases related to CD228.

Abstract: A computer-implemented method for generating an artificial data set is provided. Aspects include obtaining an input data set, calculating an association between the plurality of categorical variables of the input data set, and creating, based on the association, a plurality of clusters of categorical variables. Aspects also include identifying a key variable for each of the plurality of clusters of categorical variables, creating a key cluster for each of the plurality of clusters, and creating a cluster contingency table for each of the clusters. Aspects further include generating, based on the cluster contingency table for each of the plurality of clusters and for the key cluster, a data set for each of the plurality of clusters and the key cluster and generating the artificial data set based on a combination of the data set for each of the plurality of clusters and the key cluster.

Abstract: The present disclosure discloses an oscillating-pressure-and-spark-plasma combined sintering equipment and sintering method. By providing a system comprising a mainframe structural system, a servo motor hydraulic system, an oscillating pressurized hydraulic system, a vacuum and inert gas supply system, a pulse plasma power control system, and a mainframe control system, the mainframe structure adopts a pre-tightened frame beam to ensure the strength of the system under oscillation pressure and the stability of the overall structure. The equipment is additionally provided with an oscillation hydraulic system with adjustable frequency and pressure. During the sintering process of workpieces, the oscillation pressure can achieve the slip rearrangement of particles. It adopts an overlay mode of dual hydraulic systems. Therefore, the accuracy of pressure control in the system is ensured.

Abstract: An autonomous mobile robot and an operating method thereof are provided. The autonomous mobile robot includes a movement module, a detection module, a control module and an interaction module. The control module includes a determination unit and a navigation unit. The determination unit determines whether there is an obstacle near or on a predetermined path of the autonomous mobile robot according to the environment information. When the obstacle is on the predetermined path, the navigation unit decides an obstacle avoidance strategy according to the environment information and the type of the obstacle. The obstacle avoidance strategy at least includes moving along a side path, stopping aside to yield, moving backward and stopping at a yielding point to yield, and detouring. When the obstacle is near or on the predetermined path, the interaction module performs an interaction action according to the obstacle avoidance strategy and the type of the obstacle.

Abstract: The present disclosure provides a circuitry structure and a display substrate. The circuitry structure includes a base substrate, and a functional transistor and a signal transmission line arranged on the base substrate. The functional transistor includes a first conductive connection member, a first electrode, a second electrode, at least two gate electrode patterns and at least one active pattern. Orthogonal projections of the first electrode, the second electrode and the at least two gate electrode patterns onto the base substrate at least partially overlap with an orthogonal projection of the active pattern onto the base substrate, and first ends of the gate electrode patterns are coupled to each other. The first conductive connection member is arranged at a layer different from the gate electrode pattern, and coupled to second ends of the gate electrode patterns. The signal transmission line is coupled to the first conductive connection member.

Abstract: A tumor neoantigen prediction method and a tumor neoantigen prediction system are provided. In the method, multiple amino acid sequences in genes of a person to be tested are extracted as multiple test peptides to be compared with multiple human protein sequences in a protein sequence database to find multiple similar peptides that match the human protein sequences. The similar peptides are filtered out from the test peptides and the filtered test peptides are input to multiple trained human leukocyte antigen (HLA) models to obtain multiple ranking results of the test peptides. A weighted sum of rankings of each test peptide in the ranking results is calculated as a score of the test peptide. At least one of the test peptides is selected as a neoantigen adapted for the person to be tested according to the score.

Abstract: A neural network parameter quantization method includes obtaining a parameter of each neuron in a to-be-quantized model to obtain a parameter set, clustering parameters in the parameter set to obtain types of classified data, and quantizing each type of classified data in the types of classified data to obtain at least one type of quantization parameter, where the at least one type of quantization parameter is used to obtain a compression model, and precision of the at least one type of quantization parameter is lower than precision of a parameter in the to-be-quantized model.

Abstract: Provided are a display substrate and a display device. The display substrate includes a driving transistor and a storage capacitor, the storage capacitor includes a first electrode plate and a second electrode plate, the second electrode plate is arranged in a same layer as the channel of the driving transistor, the second electrode plate is closer to the base substrate than the first electrode plate, an orthographic projection of the second electrode plate on the base substrate overlaps with an orthographic projection of the pixel opening on the base substrate, the display substrate satisfies a following relationship: a value range of (W*L+S2)*M1/M2 is [0.014, 0.133], and a value range of S2/(W*L) is [2.82, 28.