Abstract: An optimizing device for freely switching RBC removal and plasma exchange are provided, which is used to solve the problems in the prior art that the treatment effect is poor, the consumption of consumables is excessive, and the application range is narrow. According to the device, an additional hanging hook is added, a plasma exchange output pipeline is modified to be separated from the plasma collection pump and to be installed to the additional hanging hook. Then, the RBC recirculation tube is clamped through a freely movable cassette, so that the flow rate control of a plasma collection pump is released. Thereafter, HCT data is adjusted, and liquid is compensated, so that the RBC removal or replacement, lymphoplasma exchange and plasma exchange can be freely switched, which can meet the clinical treatment needs, optimize the process and reduce the cost. Therefore, the application range of a pipeline is greatly increased.

Abstract: Provided herein are methods of treating chemotherapy-induced neutropenia in a patient in need thereof by administering to the patient an effective amount of Eflapegrastim. Also provided herein are methods of treating radiation-induced neutropenia in a patient in need thereof by administering to the patient an effective amount of Eflapegrastim.

Abstract: An optimizing device for freely switching RBC removal and plasma exchange are provided, which is used to solve the problems in the prior art that the treatment effect is poor, the consumption of consumables is excessive, and the application range is narrow. According to the device, an additional hanging hook is added, a plasma exchange output pipeline is modified to be separated from the plasma collection pump and to be installed to the additional hanging hook. Then, the RBC recirculation tube is clamped through a freely movable cassette, so that the flow rate control of a plasma collection pump is released. Thereafter, HCT data is adjusted, and liquid is compensated, so that the RBC removal or replacement, lymphoplasma exchange and plasma exchange can be freely switched, which can meet the clinical treatment needs, optimize the process and reduce the cost. Therefore, the application range of a pipeline is greatly increased.

Abstract: The present application provides a target object display method and apparatus and an electronic device, relating to the technical field of target object display. The method comprises: displaying at least two image preview areas; and for each image preview area, executing the following operations: displaying a video comprising a target object in the corresponding image preview area; and according to a trigger instruction, displaying the target object in the corresponding image preview area in a freeze-frame mode.

Abstract: An electromechanical manipulandum device can include: a drive system having a plurality of electrical motors; an arm driveable by the drive system and having three degrees-of-freedom of motion; a capstan transmission for transmitting actuating force from the drive system to the arm; an end-effector coupled to the arm, the end-effector configured to engage a user and having at least three degrees-of-freedom of rotational motion; and a control system for controlling the drive system such as to provide a force to the end-effector in a selected direction.

Abstract: Provided herein are methods for administering a hepatitis B virus surface antigen (HBsAg) to subjects with chronic hepatitis B to distinguish between responder subjects who respond to the HBsAg administration with an increase in an HBV antibody levels and non-responder subjects, and treating chronic hepatitis B in the responder subjects with an HBV therapy. Methods of excluding non-responder subjects from a clinical study are also provided.

Abstract: A metamaterial force sensor, the sensor comprising: one or more metamaterial modules, each module comprising a plurality of mechanical unit cells operatively interconnected to allow force transmission therethrough; a transducer operatively coupled to the or each module, the transducer being configured to output a signal corresponding to a displacement of the or each module in response to a force transmission, wherein each of the mechanical unit cells provides a predetermined range of displacement, based on preconfigured structural parameters of said unit cell, in response to force transmissions, and wherein at least two of the mechanical unit cells of the or each module are configured with different predetermined ranges of displacement in response to force transmissions resulting in multiple sensitivity regimes.

Abstract: The present application provides a target object display method and apparatus and an electronic device, relating to the technical field of target object display. The method comprises: displaying at least two image preview areas; and for each image preview area, executing the following operations: displaying a video comprising a target object in the corresponding image preview area; and according to a trigger instruction, displaying the target object in the corresponding image preview area in a freeze-frame mode. The target object display method provided in the present application can improve the user's shooting experience.

Abstract: A method is described for seismic depth uncertainty analysis including receiving wavelet basis functions and cutoff thresholds and randomly perturbing wavelet coefficients in reduced wavelet space based on the wavelet basis functions and the cutoff thresholds to generate a plurality of random wavelet fields; receiving a reference model in a depth domain; transforming the plurality of random wavelet fields to the depth domain and combining them with the reference model to form candidate models; performing a hierarchical Bayesian modeling with Markov Chain Monte Carlo (MCMC) sampling methods using the candidate models as input to generate a plurality of realizations; and computing statistics of the plurality of realizations to estimate depth uncertainty. The method may be executed by a computer system.

Abstract: The present invention is directed to a dry suspension for reconstitution containing Tecovirimat (ST-246) powder and simethicone. The dry suspension is dispersed in water to provide an aqueous pharmaceutical suspension formulation for oral administration for treating orthopoxvirus infections and/or eczema vaccinatum. The suspension formulation exhibits excellent stability and good dissolution and has an improved taste and texture.

Abstract: The present invention makes public a method and an apparatus for the revalorization of various organic waste, by means of physics and mechanics. The bubbles are produced and injected into the mixture in the sealed tank under depressure, then establish the movement of toric rotation in the vertical direction. The high-speed movement bubble carrying focused energy vigorously collide into the mixture, thus showing the Rheo-fluidizing effect (Shear thinning), decreasing the viscosity and depolymerizing long-chain molecules. This achieves active bacteria killing, separation, concentration and de-emulsification; the solution's advantage is applied to various organic residue, with short and efficient processing cycles, without producing unpleasant odors and is non-polluting, chemical free, at low temperature, low energy consumption, no GHG emission, preserving the microorganisms and nutrients of organic matter, and separating the pollutants such as the oils and fats.

Abstract: A method is described for seismic depth uncertainty analysis including receiving wavelet basis functions and cutoff thresholds and randomly perturbing wavelet coefficients in reduced wavelet space based on the wavelet basis functions and the cutoff thresholds to generate a plurality of random wavelet fields; receiving a reference model in a depth domain; transforming the plurality of random wavelet fields to the depth domain and combining them with the reference model to form candidate models; performing a hierarchical Bayesian modeling with Markov Chain Monte Carlo (MCMC) sampling methods using the candidate models as input to generate a plurality of realizations; and computing statistics of the plurality of realizations to estimate depth uncertainty. The method may be executed by a computer system.

Abstract: The present technology is directed to determine that an autonomous vehicle needs remote assistance. The present technology may include receiving inputs into a stuck detection algorithm, the inputs including data descriptive of an environment in which the autonomous vehicle is located at a first time, objects surrounding the AV in the environment, data perceived by the autonomous vehicle prior to the first time, and events occurring in an AV stack leading up to a current state. The present technology may also include classifying the current AV state as stuck based on the received inputs by the stuck detection algorithm and initiating remote assistance session.

Abstract: The present invention is directed to a dry suspension for reconstitution containing Tecovirimat (ST-246) powder and simethicone. The dry suspension is dispersed in water to provide an aqueous pharmaceutical suspension formulation for oral administration for treating orthopoxvirus infections and/or eczema vaccinatum. The suspension formulation exhibits excellent stability and good dissolution and has an improved taste and texture.

Abstract: The present invention discloses a generative adversarial network-based optimization (GAN-O) method. The method includes: transforming an application into a function optimization problem; establishing a GAN-based function optimization model based on a test function and a test dimension of the function optimization problem, including constructing a generator G and a discriminator D based on the GAN; training the function optimization model by training the discriminator and the generator alternatively, to obtain a trained function optimization model; and using the trained function optimization model to perform iterative calculation to obtain an optimal solution. In this way, the optimal solution is obtained based on the GAN. The present invention can improve the parameter training process of a deep neural network to obtain a better local optimal solution in a shorter time, making the training of the deep neural network more stable and obtaining better local search results.

Abstract: The present invention is directed to a dry suspension for reconstitution containing Tecovirimat (ST-246) powder and simethicone. The dry suspension is dispersed in water to provide an aqueous pharmaceutical suspension formulation for oral administration for treating orthopoxvirus infections and/or eczema vaccinatum. The suspension formulation exhibits excellent stability and good dissolution and has an improved taste and texture.

Abstract: A spectrally-resolved Raman water lidar, including: a transmitter unit, a receiver unit, and a data acquisition and control unit. The transmitter unit includes a seeder, a solid Neodymium-doped Yttrium Aluminum Garnet (Nd:YAG) laser, a beam expander, and a first reflecting mirror to emit a 354.8-nm laser beam. The receiver unit includes a telescope, an iris, a collimator, a second reflecting mirror, a first bandpass filter, a beam splitter, a narrow-band interference filter, a third lens, a first detector, a second bandpass filter, a coupler and a home-made dual-grating polychromator to enable simultaneous profiling of backscattered Raman spectrum signals from water vapor, water droplets and ice crystals as well as aerosol fluorescence in the atmosphere. The data acquisition and control unit includes a computer to store the acquired data and guarantee an automatic operation of the lidar system through a time-sequence circuit.

Abstract: An electromechanical manipulandum device, comprising: a drive system comprising a plurality of electrical motors; an arm driveable by the drive system and having three degrees-of-freedom of motion; a capstan transmission for transmitting actuating force from the drive system to the arm; an end-effector coupled to the arm, the end-effector configured to engage a user and having at least three degrees-of-freedom of rotational motion; and a control system for controlling the drive system such as to provide a force to the end-effector in a selected direction.

Abstract: The present invention is directed to a dry suspension for reconstitution containing Tecovirimat (ST-246) powder and simethicone. The dry suspension is dispersed in water to provide an aqueous pharmaceutical suspension formulation for oral administration for treating orthopoxvirus infections and/or eczema vaccinatum. The suspension formulation exhibits excellent stability and good dissolution and has an improved taste and texture.

Abstract: The present invention discloses a generative adversarial network-based optimization (GAN-O) method. The method includes: transforming an application into a function optimization problem; establishing a GAN-based function optimization model based on a test function and a test dimension of the function optimization problem, including constructing a generator G and a discriminator D based on the GAN; training the function optimization model by training the discriminator and the generator alternatively, to obtain a trained function optimization model; and using the trained function optimization model to perform iterative calculation to obtain an optimal solution. In this way, the optimal solution is obtained based on the GAN. The present invention can improve the parameter training process of a deep neural network to obtain a better local optimal solution in a shorter time, making the training of the deep neural network more stable and obtaining better local search results.