Patents by Inventor Ying Xia

Ying Xia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260036582
    Abstract: A novel immunoassay format design for determining a total antibody, and a kit accordingly provided for detecting antibodies of a pathogen or pathogens of infectious diseases within a human blood sample are provided. The kit includes: a first reagent containing at least one antigen coated on a solid phase support and an anti-human IgM antibody coated on a solid phase support; and a second reagent containing at least one labelled antigen and a labelled anti-human IgG antibody. At least one antigen of the at least one antigen coated on a solid phase support and at least one antigen of the at least one labelled antigen can bind to the same IgG antibody or the same IgM antibody in the sample. In addition, also provided is a new method for detecting an antibody produced after the infection of a pathogen or pathogens in a sample.
    Type: Application
    Filed: August 14, 2025
    Publication date: February 5, 2026
    Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Di WANG, Jianwen HE, Ying XIA
  • Patent number: 12396506
    Abstract: A breathable, high-visibility garment comprising an apertured fabric and a non-occlusive, unsupported, retroreflective laminate that is adhesively bonded to an outer major surface of at least one region of the apertured fabric.
    Type: Grant
    Filed: September 15, 2021
    Date of Patent: August 26, 2025
    Assignee: 3M Innovative Properties Company
    Inventors: Lok-Man Ng, Michael A. McCoy, Shri Niwas, Ying Xia
  • Publication number: 20250264645
    Abstract: A retroreflective article includes a mesh layer including a plurality of interconnected portions defining a plurality of enclosed openings therebetween, a bond layer, and a plurality of sets of optical elements. The bond layer includes a plurality of bond portions at least partially spaced apart from each other by the mesh layer. Each bond portion is at least partially disposed within a corresponding enclosed opening and fixedly bonded to one or more adjacent interconnected portions of the mesh layer. The plurality of sets of optical elements corresponds to the plurality of bond portions of the bond layer. Each of the sets of optical elements includes a plurality of optical elements partially embedded within a corresponding bond portion from the plurality of bond portions of the bond layer. The sets of optical elements are spaced apart from each other by the one or more interconnected portions of the mesh layer.
    Type: Application
    Filed: March 29, 2023
    Publication date: August 21, 2025
    Inventors: Lok-Man Ng, Shri Niwas, Ying Xia, Michael A. McCoy, Kui Chen-Ho
  • Publication number: 20250121433
    Abstract: The present disclosure discloses an oscillating-pressure-and-spark-plasma combined sintering equipment and sintering method. By providing a system comprising a mainframe structural system, a servo motor hydraulic system, an oscillating pressurized hydraulic system, a vacuum and inert gas supply system, a pulse plasma power control system, and a mainframe control system, the mainframe structure adopts a pre-tightened frame beam to ensure the strength of the system under oscillation pressure and the stability of the overall structure. The equipment is additionally provided with an oscillation hydraulic system with adjustable frequency and pressure. During the sintering process of workpieces, the oscillation pressure can achieve the slip rearrangement of particles. It adopts an overlay mode of dual hydraulic systems. Therefore, the accuracy of pressure control in the system is ensured.
    Type: Application
    Filed: December 27, 2023
    Publication date: April 17, 2025
    Applicants: Precision Industry Revolution Equipment Technology (Henan) Co., Ltd., ZHENGZHOU RESEARCH INSTITUTE FOR ABRASIVES & GRINDING CO., LTD.
    Inventors: Jiong ZHAO, Ning YAN, Jun WEI, Yanjun ZHAO, Jianfeng CAO, Xiangxu MENG, Ruifeng HAN, Yang ZHANG, Xiaolei WU, Ying XIA
  • Patent number: 12271010
    Abstract: A retroreflective article including a binder layer and a plurality of retroreflective elements. Each retroreflective element includes a transparent microsphere partially embedded in the binder layer. At least some of the retroreflective elements include a reflective layer that is a locally-laminated reflective layer that is embedded between the transparent microsphere and the binder layer. At least some of the locally-laminated reflective layers may be localized reflective layers.
    Type: Grant
    Filed: May 12, 2022
    Date of Patent: April 8, 2025
    Assignee: 3M Innovative Properties Company
    Inventors: Kevin W. Gotrik, Kui Chen-Ho, Scott J. Jones, Michael A McCoy, Christopher A. Merton, Shri Niwas, Ramasubramani Kuduva Raman Thanumoorthy, Ying Xia
  • Publication number: 20250059383
    Abstract: An antimicrobial article includes a supporting layer and an antimicrobial layer. The antimicrobial layer has a first major surface at least partially formed by a plurality of particles and a second major surface coupled to the supporting layer. Each particle of the plurality of particles is formed by a bead of nonconductive material. A first set of the particles include beads coated by a first conductive material.
    Type: Application
    Filed: December 2, 2022
    Publication date: February 20, 2025
    Inventors: Lijun Zu, Minghua Dai, Stephen A. O. Olson, Ying Xia, Qihong Nie, Yen-Lin Wu
  • Patent number: 12228755
    Abstract: A retroreflective article comprises a binder layer and a plurality of retroreflective elements, each retroreflective element comprising a transparent microsphere partially embedded in the binder layer. At least some of the retroreflective elements comprise a first locally laminated layer and a second locally laminated layer that may be reflective layers. A transfer article comprises a disposable carrier layer in which the retroreflective article is detachably disposed with at least some of the transparent microspheres in contact with the disposable carrier layer.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: February 18, 2025
    Assignee: 3M Innovative Properties Company
    Inventors: Kevin W. Gotrik, Kui Chen-Ho, Graham M. Clarke, Scott J. Jones, Michael A. McCoy, Shri Niwas, David J. Rowe, Tien Yi T. H. Whiting, Ying Xia
  • Patent number: 12099220
    Abstract: A retroreflective article including a binder layer and a plurality of retroreflective elements. Each retroreflective element includes a transparent microsphere partially embedded in the binder layer. At least some of the retroreflective elements include a reflective layer that is embedded between the transparent microsphere and the binder layer. At least some of the embedded reflective layers are localized reflective layers.
    Type: Grant
    Filed: September 30, 2022
    Date of Patent: September 24, 2024
    Assignee: 3M Innovative Properties Company
    Inventors: Kui Chen-Ho, Ann M. Gilman, Kevin W. Gotrik, Scott J. Jones, Daniel M. Lentz, Michael A. McCoy, Shri Niwas, Matthew S. Stay, Ramasubramani Kuduva Raman Thanumoorthy, Ying Xia
  • Publication number: 20230358918
    Abstract: The present invention belongs to the technical field of marine exploration, and discloses a forward physical simulation method for seismic response characteristics of a marine natural gas hydrate system. A physical model is established according to distribution characteristics of a hydrate system in a research area; seismic response characteristics of natural gas hydrates and underlying free gas are determined; and a seismic interpretation result of the natural gas hydrate system is corrected according to a forward physical simulation result, so that forward physical simulation of the marine natural gas hydrate system is realized.
    Type: Application
    Filed: June 1, 2023
    Publication date: November 9, 2023
    Applicants: China University of Petroleum (East China), Sanya Institute of South China Sea Geology, Guangzhou Marine Geological Survey
    Inventors: Jinxiu YANG, Jinlei XIA, Wei ZHANG, Shaogui DENG, Yong CHEN, Zhoutuo WEI, Ying XIA
  • Publication number: 20230337758
    Abstract: A breathable, high-visibility garment comprising discrete islands of unsupported, retroreflective laminate.
    Type: Application
    Filed: September 20, 2021
    Publication date: October 26, 2023
    Inventors: Ying Xia, Shri Niwas, Michael A. McCoy, Lok-Man Ng
  • Patent number: 11752731
    Abstract: Articles that include at least one application layer; at least one bead bond layer (10); a layer of optical elements (20) that are partially embedded in the at least one bead bond layer (10); and at least one reflective layer (30) that is located functionally between the layer of optical elements (20) and the bead bond layer (10), wherein the at least one bead bond layer (10), the at least one application layer, or both comprise a cured product of an adhesive compositions that include polymerized units of one or more (meth)acrylate ester monomers derived from an alcohol containing 1 to 14 carbon atoms; at least one of urethane acrylate polymer or at least one acrylic copolymer; and at least one initiator.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: September 12, 2023
    Assignee: 3M Innovative Properties Company
    Inventors: Ying Xia, Tien Yi T. H. Whiting, Shri Niwas, Duane D. Fansler, Carla S. Thomas, Anthony F. Schultz, Alexander J. Kugel, Corinne E. Lipscomb, Mary M. Caruso Dailey, Jonathan E. Janoski
  • Publication number: 20230142645
    Abstract: Described herein is a multilayered article and methods of making and using such articles. The multilayered article comprises: · (a) a microsphere layer comprising a plurality of microspheres (11) disposed in a monolayer; · (b) a bead bonding layer (12) comprising a first major surface and a second opposing major surface wherein the plurality of microspheres is at least partially embedded in the first major surface of the bead bonding layer, and wherein the bead bonding layer comprises a thermoset polyurethane, and wherein the thermoset polyurethane is derived from one or more liquid polyols; and · (c) an elastomeric layer (14) disposed on the second opposing major surface of the bead bonding layer.
    Type: Application
    Filed: April 9, 2021
    Publication date: May 11, 2023
    Inventors: Yongshang Lu, Charlie C. Ho, Ryan M. Braun, John J. Jaros, Shri Niwas, Ying Xia
  • Publication number: 20230105298
    Abstract: Articles that include at least one application layer; at least one bead bond layer (10); a layer of optical elements (20) that are partially embedded in the at least one bead bond layer (10); and at least one reflective layer (30) that is located functionally between the layer of optical elements (20) and the bead bond layer (10), wherein the at least one bead bond layer (10), the at least one application layer, or both comprise a cured product of an adhesive compositions that include polymerized units of one or more (meth)acrylate ester monomers derived from an alcohol containing 1 to 14 carbon atoms; at least one of urethane acrylate polymer or at least one acrylic copolymer; and at least one initiator.
    Type: Application
    Filed: June 27, 2018
    Publication date: April 6, 2023
    Inventors: Ying Xia, Tien Yi T. H. Whiting, Shri Niwas, Duane D. Fansler, Carla S. Thomas, Anthony F. Schultz, Alexander J. Kugel, Corinne E. Lipscomb, Mary M. Caruso Dailey, Jonathan E. Janoski
  • Publication number: 20230031047
    Abstract: A retroreflective article including a binder layer and a plurality of retroreflective elements. Each retroreflective element includes a transparent microsphere partially embedded in the binder layer. At least some of the retroreflective elements include a reflective layer that is embedded between the transparent microsphere and the binder layer. At least some of the embedded reflective layers are localized reflective layers.
    Type: Application
    Filed: September 30, 2022
    Publication date: February 2, 2023
    Inventors: Kui Chen-Ho, Ann M. Gilman, Kevin W. Gotrik, Scott J. Jones, Daniel M. Lentz, Michael A. McCoy, Shri Niwas, Matthew S. Stay, Ramasubramani Kuduva Raman Thanumoorthy, Ying Xia
  • Patent number: 11560411
    Abstract: The present disclosure provides the use of a recombinant human secretory DDRGK1. Experiments demonstrate that the recombinant human secretory DDRGK1 prepared by the present disclosure can be used in the preparation of biological medicines for treating intervertebral disc degeneration, fractures or bone defects. The recombinant human secretory DDRGK1 of the present disclosure provides a promising direction for the treatment of bone related diseases and has obtained firm scientific evidence, thereby expanding the further application of recombinant human secretory DDRGK1 in clinical practice.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: January 24, 2023
    Assignee: SHANGHAI NINTH PEOPLE'S HOSPITAL, SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Tangjun Zhou, Ying Xia, Xiao Yang, An Qin, Yu Cao, Jie Zhao
  • Publication number: 20220365260
    Abstract: A retroreflective article including a binder layer and a plurality of retroreflective elements. Each retroreflective element includes a transparent microsphere partially embedded in the binder layer and a discontinuous binder-borne reflective layer that is provided by a portion of a fractured binder-borne reflective sheet.
    Type: Application
    Filed: September 29, 2020
    Publication date: November 17, 2022
    Inventors: Kui Chen-Ho, Graham M. Clarke, Kevin W. Gotrik, Michael A. McCoy, Christopher A. Merton, Aaron M. Nash, Shri Niwas, Anthony F. Schultz, Carla S. Thomas, Tien Yi T.H. Whiting, Ying Xia, Scott J. Jones
  • Patent number: 11493674
    Abstract: A retroreflective article including a binder layer and a plurality of retroreflective elements. Each retroreflective element includes a transparent microsphere partially embedded in the binder layer. At least some of the retroreflective elements include a reflective layer that is embedded between the transparent microsphere and the binder layer. At least some of the embedded reflective layers are localized reflective layers.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: November 8, 2022
    Assignee: 3M Innovative Properties Company
    Inventors: Kui Chen-Ho, Ann M. Gilman, Kevin W. Gotrik, Scott J. Jones, Daniel M. Lentz, Michael A. McCoy, Shri Niwas, Matthew S. Stay, Ramasubramani Kuduva Raman Thanumoorthy, Ying Xia
  • Publication number: 20220276417
    Abstract: A retroreflective article including a binder layer and a plurality of retroreflective elements. Each retroreflective element includes a transparent microsphere partially embedded in the binder layer. At least some of the retroreflective elements include a reflective layer that is a locally-laminated reflective layer that is embedded between the transparent microsphere and the binder layer. At least some of the locally-laminated reflective layers may be localized reflective layers.
    Type: Application
    Filed: May 12, 2022
    Publication date: September 1, 2022
    Inventors: Kevin W. Gotrik, Kui Chen-Ho, Scott J. Jones, Michael A. McCoy, Christopher A. Merton, Shri Niwas, Ramasubramani Kuduva Raman Thanumoorthy, Ying Xia
  • Patent number: 11415731
    Abstract: A retroreflective article including a reflective-particle-containing binder layer and a plurality of retroreflective elements. Each retroreflective element includes a transparent microsphere partially embedded in the binder layer. At least some of the retroreflective elements comprise a primary reflective layer that covers a portion of the embedded surface area of the transparent microsphere, and a secondary reflective layer provided by portions of the reflective-particle-containing binder layer that are adjacent to portions of the embedded surface area of the transparent microsphere that are not covered by the primary reflective layer.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: August 16, 2022
    Assignee: 3M Innovative Properties Company
    Inventors: Michael A. McCoy, Ying Xia, Lok-Man Ng, Shri Niwas, Scott J. Jones, Kevin W. Gotrik, Kui Chen-Ho
  • Publication number: 20220214478
    Abstract: A retroreflective article comprises a binder layer and a plurality of retroreflective elements, each retroreflective element comprising a transparent microsphere partially embedded in the binder layer. At least some of the retroreflective elements comprise a first locally laminated layer and a second locally laminated layer that may be reflective layers. A transfer article comprises a disposable carrier layer in which the retroreflective article is detachably disposed with at least some of the transparent microspheres in contact with the disposable carrier layer.
    Type: Application
    Filed: April 24, 2020
    Publication date: July 7, 2022
    Inventors: Kevin W. Gotrik, Kui Chen-Ho, Graham M. Clarke, Scott J. Jones, Michael A. McCoy, Shri Niwas, David J. Rowe, Tien Yi T.H. Whiting, Ying Xia