Abstract: Aspects include a method that includes receiving a structured query language (SQL) database command at a processing device configured to manage a table space of a relational database, the database command including a merge statement. The method also includes identifying a group of target records from the database command, and associating each target record with one of a plurality of portions of the table space, and in response to determining that the group of target records is associated with more than one portion of the table space, sorting the target records into a plurality of sub-groups, each sub-group associated with a different portion of the table space. The method further includes generating a sub-task associated with each sub-group, the sub-task prescribing aspects of performing the merge operation using an associated sub-group respective sub-group, and performing all of the sub-tasks on the memory space in parallel.

Abstract: The invention provides stable aqueous pharmaceutical formulations comprising an anti-PDL1 antibody. The invention also provides methods for making such formulations and methods of using such formulations.

Abstract: A hybrid power supply system of diesel multiple unit is disclosed. When a train is running, an energy management module sends a level signal of a master controller of the train to an inverter, and the inverter, according to the received level signal of the master controller and the dynamic performance of the hybrid power supply system, sets an envelope curve of train speed vs. traction force and an envelope curve of train speed vs. regenerative braking force to control a traction motor to output the corresponding torque.

Abstract: The disclosure provides an adjustable fixing assembly. The adjustable fixing assembly includes a base plate and a cover plate. The cover plate includes a plate portion and a protrusion portion protruding from the plate portion. The cover plate includes a first installation position and a second installation position. When the cover plate is in the first installation position, the protrusion portion extends away from the base plate, and the cover plate is spaced apart from the base plate by a first minimum distance. When the cover plate is in the second installation position, the protrusion portion extends towards the base plate, and the cover plate is spaced apart from the base plate by a second minimum distance, where the second minimum distance is smaller than the first minimum distance.

Abstract: The present disclosure provides compositions that enable sustained release of a small molecule tyrosine kinase inhibitor, such as axitinib from a bioerodible polyester polymer implant for the treatment of disease. The composition is especially suitable for treating ophthalmic indications, such as neovascular age related macular degeneration and diabetic macular edema, by intravitreal injection of the implant. The implant is designed to be pre-loaded into a small diameter needle and injected via self-sealing scleral needle penetration at the pars plana. Small molecule tyrosine kinase inhibitors may be released from the implants over a period of one week to three years.

Abstract: An electrode for use in a lithium-ion battery. The electrode comprises a group IV-VI compound and a transition metal group VI compound on a three-dimensional graphene network. A major portion of the transition metal group VI compound is provided on top of the group IV-VI compound or in close proximity to it, whereby the molybdenum group VI compound contributes to the decomposition of a lithium group VI compound at the surface of the group IV-VI compound.

Abstract: A Fe—Ni based alloy comprising, in weight percent: Ni 30-35; Cr 12-14; Al 3-5; Ti 0-2; Ta 2-8; C<=0.05; B<=0.005; Zr<=0.2; Si<0.5; where Cr/(Cr+Fe+Ni)=0.125-0.145; Al/(Al+Ti+Ta)=0.15-0.5; and Fe?Ni; balance Fe, the alloy having a face-centered cubic (fcc) matrix with from 25 to 30 vol. % of L12-type ??-Ni3M (M=Al, Ta, Ti and mixtures thereof) precipitates.

Abstract: Compositions comprising covalently modified and mutated biotin-binding proteins, particularly biotin-binding proteins having a negative charge at physiological pH, are provided. Methods of producing such proteins are also provided, as are methods of immobilizing, sequencing, and making nucleic acids employing such proteins.

Abstract: A lithium (Li) ion battery includes a first electrode with a second electrode, and a shutdown polymer additive on an outer surface of the first electrode. The shutdown polymer additive includes at least two polyethylene layers, each polyethylene layer comprising a plurality of polyethylene microspheres. Each polyethylene microsphere is wrapped with carbon nanotubes. The polyethylene microspheres interconnect with each other such that the carbon nanotubes form a conductive network. The polyethylene layers are provided at predetermined areas of the outer surface of the first electrode.

Abstract: The present invention is directed to a depot composition for sustained release delivery of buprenorphine with enhanced stability and bioavailability. The composition is an injectable, low viscosity liquid and can form a depot in situ capable of delivering therapeutic level of buprenorphine over a period of time from one week to 3 months.

Abstract: A content delivery network (CDN) management system is provided. The CDN management system includes: a central controller; and at least one CDN node. Each of the at least one CDN node includes: a node controller connected to the central controller, at least one service server, and a switch connected to the node controller and each service server. The central controller is configured to receive a task invoking request, generate a management task according to the task invoking request, and send the management task to the node controller, the task invoking request indicating a request to perform remote management on one service server of the at least one service server of the CDN node, and the node controller is configured to receive the management task sent by the central controller, and control the service server based on the management task.

Abstract: Embodiments of the present invention provide efficient systems and methods for searching a keyword. Embodiments of the present invention can be used to more quickly and comprehensively search a document for a keyword or phrase, based on the preferences and behaviors of a user, so that the returned results to the user are ranked in order of the preferences of the user. By factoring in user data such as time spent on certain content and highlighted content, the system is able to more efficiently return preferred results of a user of a keyword search.

Abstract: A delay locked loop detection system (10), the system can be used for detecting the working state of a delay locked loop (400) and comprises: a signal generator (300), which is used for generating a reference clock and providing the reference clock to the delay locked loop (400); and a testing instrument (500), which is used for acquiring the clock signals output from the delay locked loop (400) and measuring whether the time delays thereof are consistent with expectations; the detection system (10) further comprises at least one of the following circuits: a pre-receiving circuit (100), which is used for receiving the reference clock from the signal generator (300) and amplifying and shaping the reference clock and then providing the reference clock to the delay locked loop (400); and a multiphase multiplexing circuit (200), which is used for receiving the clock signals output from the delay locked loop (400) and synthesizing and then providing a plurality of clock signals with different delay to the testing

Abstract: The present invention provides a compound of formula (1): wherein X, Y, Z1, Z2, R1, R2, A, B, p and q are as disclosed in the specification. A pharmaceutical composition and a method for modulating the Hedgehog pathway are also provided. The present invention rurthe r provides a process for preparing the compound.

Abstract: The present invention relates to new immunogenic compositions comprising conjughated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates) and uses thereof. Immunogenic compositions of the present invention will typically comprise at least one glycoconjugate from a S. pneumoniae serotype not found in PREVNAR®, SYNFLORIX® and/or PREVNAR 13®. The invention also relates to vaccination of human subjects, in particular infants and elderly, against pneumococcal infections using said novel immunogenic compositions.

Abstract: A pacemaker fixation system, a leadless pacemaker system and a method of use thereof are disclosed. The leadless pacemaker system includes: a pacemaker fixation system including a leadless pacemaker and an elastic unfoldable element attached thereto, wherein in an unfolded configuration of the elastic unfoldable element, it fixes the leadless pacemaker at a target location in a blood vessel in communication with the heart; a delivery system for delivering the pacemaker fixation system to the target location; and a guide for guiding the delivery system into the blood vessel. According to the present invention, atrial pacing can be achieved by the leadless pacemaker through fixing the leadless pacemaker in the blood vessel in communication with the heart with the elastic unfoldable element.

Abstract: A technique relates to determining when to skip a group by clause in a query. A computer checks that a condition is satisfied for a table. The condition is selected from the group consisting of having a unique index on one or more columns of the table or having a function on the one or more columns that makes rows in the GROUP BY clause unique. The group by clause is part of the query on the table. In response to the condition being satisfied, the group by clause associated with the one or more columns is skipped. In response to the condition not being satisfied, the group by clause associated with the one or more columns is executed.

Abstract: This invention relates to oral care compositions comprising zingerone, bisabolol, a stannous ion source, zinc oxide, and zinc citrate, as well as to methods of using and of making these compositions.

Abstract: A Flash memory controller for a system having first and second microcontrollers configured to perform first and second functions, and further having a Flash memory medium shared by the two microcontrollers, includes first and second execute-in-place cache controllers respectively configured to cache program code retrieved from the Flash memory for execution by the respective microcontrollers. A cache-miss arbiter controls access by the microcontrollers to the Flash memory on occurrence of a cache miss in one of the cache controllers. The arbiter may allow aborting of a first fetching operation on behalf of one of the microcontrollers upon receipt of a fetch request from the other microcontroller if the first fetching operation has retrieved a desired data unit and a threshold amount of data. The Flash memory controller may also include a decryption engine configured to decrypt encrypted program code. The decryption mode is determined from address ranges.

Abstract: A computer-implemented method includes identifying a primary database interaction statement and determining one or more intermediate database interaction statements based on the primary database interaction statement. The computer-implemented further includes determining, for each of the one or more intermediate database interaction statements, an intermediate statement transformation indicator. The computer-implemented method further includes determining one or more transformed database interaction statements based on each intermediate statement transformation indicator. A corresponding computer program product and computer system are also disclosed.