Patents by Inventor Yinghong Yu

Yinghong Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11497918
    Abstract: Systems and methods for monitoring and treating patients with heart failure (HF) are discussed. The system may sense cardiac signals, and receives information about patient physiological or functional conditions. A stimulation parameter table that includes recommended values of atrioventricular delay (AVD) or other timing parameters maybe created at a multitude of patient physiological or functional conditions. The system may periodically reassess patient physiological or functional conditions. A therapy programmer circuit may dynamically switch between left ventricular-only pacing and biventricular pacing, or switch between single site pacing and multisite pacing based on the patient condition. The therapy programmer circuit may adjust AVD and other timing parameters using the cardiac signal input and the stored stimulation parameter table. A HF therapy may be delivered according to the determined stimulation site, stimulation mode, and the stimulation timing.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: November 15, 2022
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: David J. Ternes, Yinghong Yu, Jason Humphrey, David L. Perschbacher, Michael James Dufresne, Adam MacEwen, Keith L. Herrmann
  • Patent number: 11452876
    Abstract: Systems and methods for monitoring and treating patients with heart failure are discussed. The system may receive patient atrioventricular (AV) conduction characteristic under different heart rates or patient conditions. Stimulation parameters including stimulation timing parameters may be stored in a memory. The system may include a stimulation control circuit configured to determine a parameter update schedule indicating a timing at which to update stimulation parameter using patient AV conduction characteristic, and dynamically update at least a portion of the stored set of stimulation parameters at the determined parameter update schedule. For a specified heart rate or heart rate range, a stimulation parameter may be selected from the set of the stimulation parameters for use during cardiac stimulation.
    Type: Grant
    Filed: November 25, 2019
    Date of Patent: September 27, 2022
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Qi An, Yinghong Yu
  • Publication number: 20220257948
    Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods for pacing a HIS bundle of a patient. The apparatuses, systems, and methods may include applying stimulation energy through one or more of a plurality of electrodes to direct a stimulation locus and pace a HIS bundle of a patient.
    Type: Application
    Filed: May 5, 2022
    Publication date: August 18, 2022
    Inventors: Pramodsingh H. Thakur, Allan C. Shuros, Brian Soltis, Juan G. Hincapie, Qi An, Yinghong Yu, Keith R. Maile
  • Patent number: 11338145
    Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods for pacing a HIS bundle of a patient. The apparatuses, systems, and methods may include applying stimulation energy through one or more of a plurality of electrodes to direct a stimulation locus and pace a HIS bundle of a patient.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: May 24, 2022
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Pramodsingh H. Thakur, Allan C. Shuros, Brian Soltis, Juan G. Hincapie, Qi An, Yinghong Yu, Keith R. Maile
  • Patent number: 11318313
    Abstract: This document discusses, among other things, systems and methods to determine a response between received cardiac electrical information from a subject, such as a time of a P wave, and received cardiac acceleration information of the subject, such as a time of a first heart sound (S1) or a second heart sound (S2), across a set of stimulation signals provided to the subject at different AVD intervals, and determining one or more cardiac resynchronization therapy (CRT) parameters using an inflection point of the determined response.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: May 3, 2022
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Yinghong Yu, Krzysztof Z. Siejko, Qi An
  • Patent number: 11311731
    Abstract: This document discusses, among other things, systems and methods to determine a response curve between received cardiac electrical information from a subject, such as a time of a P wave, and received cardiac acceleration information of the subject, such as a time of a first heart sound (S1) or a second heart sound (S2), to a set of stimulation signals provided to the subject at different AVD intervals. In certain examples, one or more cardiac resynchronization therapy (CRT) parameters can be determined for the subject using the determined response curve.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: April 26, 2022
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Yinghong Yu, Krzysztof Z. Siejko, Qi An
  • Patent number: 11305125
    Abstract: An implantable medical device (IMD) that includes a housing, a first electrode secured relative to the housing, a second electrode secured relative to the housing, and a gyroscope secured relative to the housing. The IMD may include circuitry in the housing in communication with the first electrode, the second electrode, and the gyroscope. The circuitry may be configured to determine and store a plurality of torsion data measurements, from which a representation of a twist profile may be determined.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: April 19, 2022
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Bin Mi, Pramodsingh Hirasingh Thakur, Jeffrey E. Stahmann, Keith R. Maile, Qi An, Brendan Early Koop, Yinghong Yu, Viktoria A. Averina, Michael J. Kane, Krzysztof Z. Siejko
  • Publication number: 20220111215
    Abstract: Systems and methods for monitoring and treating patients with heart failure are discussed. The system can store in a memory stimulation parameters, including stimulation timing parameters for a plurality of heart rate ranges. The system includes a plurality of timers with respective durations for the plurality of heart rate ranges. A stimulation control circuit can identify a target heart range in which a detected heart rate falls, and measure an atrioventricular (AV) conduction characteristic value in response to the timer for the target heart range being expired at the detected heart rate. The stimulation control circuit can update a stimulation parameter corresponding to the target heart rate range using the measured AV conduction characteristic. The updated stimulation parameter can be used in cardiac stimulation.
    Type: Application
    Filed: December 22, 2021
    Publication date: April 14, 2022
    Inventors: Qi An, Yinghong Yu, Adam MacEwen
  • Patent number: 11235157
    Abstract: Systems and methods for monitoring and treating patients with heart failure are discussed. The system can store in a memory stimulation parameters, including stimulation timing parameters for a plurality of heart rate ranges. The system includes a plurality of timers with respective durations for the plurality of heart rate ranges. A stimulation control circuit can identify a target heart range in which a detected heart rate falls, and measure an atrioventricular (AV) conduction characteristic value in response to the timer for the target heart range being expired at the detected heart rate. The stimulation control circuit can update a stimulation parameter corresponding to the target heart rate range using the measured AV conduction characteristic. The updated stimulation parameter can be used in cardiac stimulation.
    Type: Grant
    Filed: November 25, 2019
    Date of Patent: February 1, 2022
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Qi An, Yinghong Yu, Adam MacEwen
  • Patent number: 11207527
    Abstract: Method and system for determining an atrial contraction timing fiducial in a leadless cardiac pacemaker system is disclosed. An electrical cardiac signal associated with an atrial contraction of the patient's heart and a mechanical response to the atrial contraction of a patient's heart are used to determine an atrial contraction timing fiducial. A ventricle pacing pulse may then be generated an A-V delay after the atrial contraction timing fiducial.
    Type: Grant
    Filed: July 5, 2017
    Date of Patent: December 28, 2021
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Qi An, Yinghong Yu, Pramodsingh Hirasingh Thakur, Krzysztof Z. Siejko
  • Patent number: 11185700
    Abstract: Systems and methods for monitoring and treating patients with heart failure (HF) are discussed. The system may sense cardiac signals, and receives information about patient physiological or functional conditions. A stimulation parameter table that includes recommended values of atrioventricular delay (AVD) or other timing parameters maybe created at a multitude of patient physiological or functional conditions. The system may periodically reassess patient physiological or functional conditions. A therapy programmer circuit may dynamically switch between left ventricular-only pacing and biventricular pacing, or switch between single site pacing and multisite pacing based on the patient condition. The therapy programmer circuit may adjust AVD and other timing parameters using the cardiac signal input and the stored stimulation parameter table. A HF therapy may be delivered according to the determined stimulation site, stimulation mode, and the stimulation timing.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: November 30, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: David J. Ternes, Yinghong Yu, Jason Humphrey, David L. Perschbacher, Michael James Dufresne, Adam MacEwen, Keith L. Herrmann
  • Patent number: 11173310
    Abstract: Devices and methods for improving device therapy such as cardiac resynchronization therapy by determining a value for a device parameter are described. An ambulatory medical device (AMD) can include a sensor circuit to sense a physiological signal and generate two or more signal metrics, and detect an event of worsening cardiac condition using the two or more signal metrics. In response to the detection of worsening cardiac condition, the AMD can determine, for a stimulator, a value of at least one stimulation parameter based on temporal responses of two or more signal metrics. The temporal responses include near-term and long-term responses to the stimulation. The AMD can program the stimulator with the determined parameter value, and generate stimulation according to the determined parameter value to stimulate target tissue.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: November 16, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Qi An, Julie A. Thompson, Yinghong Yu, Yi Zhang, Pramodsingh Hirasingh Thakur
  • Patent number: 11147965
    Abstract: A leadless cardiac pacemaker (LCP) is configured to sense cardiac activity and to pace a patient's heart and is disposable within a ventricle of the patient's heart. The LCP may include a housing, a first electrode and a second electrode that are secured relative to the housing and are spaced apart. A controller is disposed within the housing and is operably coupled to the first electrode and the second electrode such that the controller is capable of receiving, via the first electrode and the second electrode, electrical cardiac signals of the heart. The LCP may include a pressure sensor and/or an accelerometer. The controller may determine a pace time for a cardiac cycle based at least in part upon a signal from the pressure sensor.
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: October 19, 2021
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Qi An, Jeffrey E. Stahmann, Pramodsingh Hirasingh Thakur, Michael J. Kane, Yinghong Yu, Keith R. Maile
  • Patent number: 11040207
    Abstract: Systems and methods for monitoring and treating patients with heart failure (HF) are discussed. The system may sense cardiac signals, and receives information about patient physiological or functional conditions. A stimulation parameter table that includes recommended values of atrioventricular delay (AVD) or other timing parameters maybe created at a multitude of patient physiological or functional conditions. The system may periodically reassess patient physiological or functional conditions. A therapy programmer circuit may dynamically switch between left ventricular-only pacing and biventricular pacing, or switch between single site pacing and multisite pacing based on the patient condition. The therapy programmer circuit may adjust AVD and other timing parameters using the cardiac signal input and the stored stimulation parameter table. A HF therapy may be delivered according to the determined stimulation site, stimulation mode, and the stimulation timing.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: June 22, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: David J. Ternes, Yinghong Yu, Jason Humphrey, David L. Perschbacher, Michael James Dufresne, Adam MacEwen, Keith L. Herrmann
  • Patent number: 11020011
    Abstract: Arterial diastolic pressure of a patient can be estimated using ventricular pressure information of a heart of the patient and heart sound information of the heart of the patient, such as a timing of at least one of a first heart sound (S1) or a second heat sound (S2), in certain examples, adjusted by a respective correction factor.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: June 1, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Qi An, Pramodsingh Hirasingh Thakur, Michael J. Kane, Yinghong Yu, Jeffrey E. Stahmann
  • Publication number: 20210106271
    Abstract: Methods and systems for use of the Q-wave to R-wave interval to guide placement of a leadless cardiac pacemaker are disclosed. An implant delivery device is equipped with sensing electrodes to sense R-wave onset in a ventricle of a patient's heart to allow placement at a location of last or latest onset of the R-wave. Guidance tools are provided to assist in determination of the Q-wave to R-wave interval during implantation. For a chronic system, a cooperative approach is disclosed in which an implantable medical device and a leadless cardiac pacemaker exchange data to determine Q-wave to R-wave intervals and enhance cardiac resynchronization therapy delivery by the leadless cardiac pacemaker.
    Type: Application
    Filed: October 26, 2020
    Publication date: April 15, 2021
    Applicant: CARDIAC PACEMAKERS, INC.
    Inventors: STEVEN LEE EDDY, BRENDAN EARLY KOOP, YINGHONG YU
  • Patent number: 10945670
    Abstract: An apparatus comprises a respiration sensing circuit configured for coupling electrically to a plurality of electrodes and for sensing a respiration signal representative of respiration of a subject; a signal processing circuit electrically coupled to the respiration sensing circuit and configured to extract a respiration parameter from a sensed respiration signal and determine a signal performance metric for the sensed respiration signal using the respiration parameter; and a control circuit. The control circuit is configured to: initiate sensing of a plurality of respiration signals using different electrode combinations of the plurality of electrodes and determining of the signal performance metric for the sensed respiration signals; and enable an electrode combination from the plurality of electrodes and for use in monitoring respiration of the subject according to the signal performance metric.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: March 16, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Qi An, Yinghong Yu, Yi Zhang, Viktoria A. Averina, Pramodsingh Hirasingh Thakur
  • Patent number: 10918858
    Abstract: An Implantable Medical Device (IMD) configured to be implantable in a ventricle of a patient's heart may include a housing, a first electrode secured relative to the housing, a second electrode secured relative to the housing, the second electrode spaced from the first electrode, and circuitry in the housing operatively coupled to the first electrode and the second electrode. The circuitry may be configured to identify a measure of impedance between the first electrode and the second electrode at each of a plurality of times during a cardiac cycle. Each measure of impedance may represent a measure of volume of the ventricle in which the IMD is implanted. In some cases, the circuitry may generate a pacing pulse, the timing of which is based at least in part on the measure of volume of the ventricle at two or more of the plurality of times during the cardiac cycle.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: February 16, 2021
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Qi An, Jeffrey E. Stahmann, Yinghong Yu, Pramodsingh Hirasingh Thakur, Michael J. Kane, Keith R. Maile
  • Patent number: 10905465
    Abstract: A delivery device for delivering an implantable leadless pacing device may include a catheter shaft a distal holding section for receiving the implantable leadless pacing device. In some cases, the delivery device may include a flow-sensing device to determine a pressure or flow-rate of a fluid within the distal holding section. Also included may be a handle assembly and a deployment mechanism to deploy the implantable leadless pacing device.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: February 2, 2021
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Allan Charles Shuros, Brian Soltis, Yinghong Yu, Arjun D. Sharma
  • Patent number: 10874860
    Abstract: A leadless cardiac pacemaker (LCP) is configured to sense cardiac activity and to pace a patient's heart and is disposable within a ventricle of the patient's heart. The LCP MAY include a housing, a first electrode and a second electrode that are secured relative to the housing and are spaced apart. A controller is disposed within the housing and is operably coupled to the first electrode and the second electrode such that the controller is capable of receiving, via the first electrode and the second electrode, electrical cardiac signals of the heart. The LCP may include a pressure sensor and/or an accelerometer. The controller may determine a pace time within a cardiac cycle based at least in part upon an indication of metabolic demand.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: December 29, 2020
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Qi An, Michael J. Kane, Yinghong Yu, Jeffrey E. Stahmann, Pramodsingh Hirasingh Thakur, Keith R. Maile