Patents by Inventor Yinghong Yu

Yinghong Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11147965
    Abstract: A leadless cardiac pacemaker (LCP) is configured to sense cardiac activity and to pace a patient's heart and is disposable within a ventricle of the patient's heart. The LCP may include a housing, a first electrode and a second electrode that are secured relative to the housing and are spaced apart. A controller is disposed within the housing and is operably coupled to the first electrode and the second electrode such that the controller is capable of receiving, via the first electrode and the second electrode, electrical cardiac signals of the heart. The LCP may include a pressure sensor and/or an accelerometer. The controller may determine a pace time for a cardiac cycle based at least in part upon a signal from the pressure sensor.
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: October 19, 2021
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Qi An, Jeffrey E. Stahmann, Pramodsingh Hirasingh Thakur, Michael J. Kane, Yinghong Yu, Keith R. Maile
  • Patent number: 11040207
    Abstract: Systems and methods for monitoring and treating patients with heart failure (HF) are discussed. The system may sense cardiac signals, and receives information about patient physiological or functional conditions. A stimulation parameter table that includes recommended values of atrioventricular delay (AVD) or other timing parameters maybe created at a multitude of patient physiological or functional conditions. The system may periodically reassess patient physiological or functional conditions. A therapy programmer circuit may dynamically switch between left ventricular-only pacing and biventricular pacing, or switch between single site pacing and multisite pacing based on the patient condition. The therapy programmer circuit may adjust AVD and other timing parameters using the cardiac signal input and the stored stimulation parameter table. A HF therapy may be delivered according to the determined stimulation site, stimulation mode, and the stimulation timing.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: June 22, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: David J. Ternes, Yinghong Yu, Jason Humphrey, David L. Perschbacher, Michael James Dufresne, Adam MacEwen, Keith L. Herrmann
  • Patent number: 11020011
    Abstract: Arterial diastolic pressure of a patient can be estimated using ventricular pressure information of a heart of the patient and heart sound information of the heart of the patient, such as a timing of at least one of a first heart sound (S1) or a second heat sound (S2), in certain examples, adjusted by a respective correction factor.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: June 1, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Qi An, Pramodsingh Hirasingh Thakur, Michael J. Kane, Yinghong Yu, Jeffrey E. Stahmann
  • Publication number: 20210106271
    Abstract: Methods and systems for use of the Q-wave to R-wave interval to guide placement of a leadless cardiac pacemaker are disclosed. An implant delivery device is equipped with sensing electrodes to sense R-wave onset in a ventricle of a patient's heart to allow placement at a location of last or latest onset of the R-wave. Guidance tools are provided to assist in determination of the Q-wave to R-wave interval during implantation. For a chronic system, a cooperative approach is disclosed in which an implantable medical device and a leadless cardiac pacemaker exchange data to determine Q-wave to R-wave intervals and enhance cardiac resynchronization therapy delivery by the leadless cardiac pacemaker.
    Type: Application
    Filed: October 26, 2020
    Publication date: April 15, 2021
    Applicant: CARDIAC PACEMAKERS, INC.
    Inventors: STEVEN LEE EDDY, BRENDAN EARLY KOOP, YINGHONG YU
  • Patent number: 10945670
    Abstract: An apparatus comprises a respiration sensing circuit configured for coupling electrically to a plurality of electrodes and for sensing a respiration signal representative of respiration of a subject; a signal processing circuit electrically coupled to the respiration sensing circuit and configured to extract a respiration parameter from a sensed respiration signal and determine a signal performance metric for the sensed respiration signal using the respiration parameter; and a control circuit. The control circuit is configured to: initiate sensing of a plurality of respiration signals using different electrode combinations of the plurality of electrodes and determining of the signal performance metric for the sensed respiration signals; and enable an electrode combination from the plurality of electrodes and for use in monitoring respiration of the subject according to the signal performance metric.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: March 16, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Qi An, Yinghong Yu, Yi Zhang, Viktoria A. Averina, Pramodsingh Hirasingh Thakur
  • Patent number: 10918858
    Abstract: An Implantable Medical Device (IMD) configured to be implantable in a ventricle of a patient's heart may include a housing, a first electrode secured relative to the housing, a second electrode secured relative to the housing, the second electrode spaced from the first electrode, and circuitry in the housing operatively coupled to the first electrode and the second electrode. The circuitry may be configured to identify a measure of impedance between the first electrode and the second electrode at each of a plurality of times during a cardiac cycle. Each measure of impedance may represent a measure of volume of the ventricle in which the IMD is implanted. In some cases, the circuitry may generate a pacing pulse, the timing of which is based at least in part on the measure of volume of the ventricle at two or more of the plurality of times during the cardiac cycle.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: February 16, 2021
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Qi An, Jeffrey E. Stahmann, Yinghong Yu, Pramodsingh Hirasingh Thakur, Michael J. Kane, Keith R. Maile
  • Patent number: 10905465
    Abstract: A delivery device for delivering an implantable leadless pacing device may include a catheter shaft a distal holding section for receiving the implantable leadless pacing device. In some cases, the delivery device may include a flow-sensing device to determine a pressure or flow-rate of a fluid within the distal holding section. Also included may be a handle assembly and a deployment mechanism to deploy the implantable leadless pacing device.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: February 2, 2021
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Allan Charles Shuros, Brian Soltis, Yinghong Yu, Arjun D. Sharma
  • Patent number: 10874860
    Abstract: A leadless cardiac pacemaker (LCP) is configured to sense cardiac activity and to pace a patient's heart and is disposable within a ventricle of the patient's heart. The LCP MAY include a housing, a first electrode and a second electrode that are secured relative to the housing and are spaced apart. A controller is disposed within the housing and is operably coupled to the first electrode and the second electrode such that the controller is capable of receiving, via the first electrode and the second electrode, electrical cardiac signals of the heart. The LCP may include a pressure sensor and/or an accelerometer. The controller may determine a pace time within a cardiac cycle based at least in part upon an indication of metabolic demand.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: December 29, 2020
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Qi An, Michael J. Kane, Yinghong Yu, Jeffrey E. Stahmann, Pramodsingh Hirasingh Thakur, Keith R. Maile
  • Patent number: 10870008
    Abstract: Methods, systems and devices for providing cardiac resynchronization therapy (CRT) to a patient using a leadless cardiac pacemaker and an extracardiac device. The extracardiac device is configured to analyze one or more QRS complexes of the patient's heart, determine whether fusion pacing is taking place, and, if not, to communicate with the leadless cardiac pacemaker to adjust intervals used in the CRT in order to generate desirable fusion of the pace and intrinsic signals. The extracardiac device may take the form of a subcutaneous implantable monitor, a subcutaneous implantable defibrillator, or other devices including wearable devices.
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: December 22, 2020
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Stephen J. Hahn, Kenneth M. Stein, Yinghong Yu, Scott J. Healy, John Morgan
  • Patent number: 10849522
    Abstract: Methods and systems for use of the Q-wave to R-wave interval to guide placement of a leadless cardiac pacemaker are disclosed. An implant delivery device is equipped with sensing electrodes to sense R-wave onset in a ventricle of a patient's heart to allow placement at a location of last or latest onset of the R-wave. Guidance tools are provided to assist in determination of the Q-wave to R-wave interval during implantation. For a chronic system, a cooperative approach is disclosed in which an implantable medical device and a leadless cardiac pacemaker exchange data to determine Q-wave to R-wave intervals and enhance cardiac resynchronization therapy delivery by the leadless cardiac pacemaker.
    Type: Grant
    Filed: April 2, 2018
    Date of Patent: December 1, 2020
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Steven Lee Eddy, Brendan Early Koop, Yinghong Yu
  • Publication number: 20200324121
    Abstract: This document discusses, among other things, systems and methods to determine a response between received cardiac electrical information from a subject, such as a time of a P wave, and received cardiac acceleration information of the subject, such as a time of a first heart sound (S1) or a second heart sound (S2), across a set of stimulation signals provided to the subject at different AVD intervals, and determining one or more cardiac resynchronization therapy (CRT) parameters using an inflection point of the determined response.
    Type: Application
    Filed: April 10, 2020
    Publication date: October 15, 2020
    Inventors: Yinghong Yu, Krzysztof Z. Siejko, Qi An
  • Publication number: 20200324120
    Abstract: This document discusses, among other things, systems and methods to determine a response curve between received cardiac electrical information from a subject, such as a time of a P wave, and received cardiac acceleration information of the subject, such as a time of a first heart sound (S1) or a second heart sound (S2), to a set of stimulation signals provided to the subject at different AVD intervals. In certain examples, one or more cardiac resynchronization therapy (CRT) parameters can be determined for the subject using the determined response curve.
    Type: Application
    Filed: April 10, 2020
    Publication date: October 15, 2020
    Inventors: Yinghong Yu, Krzysztof Z. Siejko, Qi An
  • Patent number: 10758737
    Abstract: A medical system for sensing and regulating cardiac activity of a patient may include a cardioverter that is configured to generate and deliver shocks to cardiac tissue and a leadless cardiac pacemaker (LCP) that is configured to sense cardiac activity and to communicate with the cardioverter. The cardioverter may be configured to detect a possible arrhythmia and, upon detecting the possible arrhythmia, may send a verification request to the LCP to help conform that the possible arrhythmia is occurring. The LCP, upon receiving the verification request from the cardioverter, may be configured to activate one or more of a plurality of sensors to attempt to help confirm that the possible arrhythmia is occurring.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: September 1, 2020
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Qi An, Pramodsingh Hirasingh Thakur, Jeffrey E. Stahmann, Yinghong Yu, Michael J. Kane
  • Patent number: 10758724
    Abstract: A delivery and deployment device may include a handle assembly and a shaft extending distally from the handle assembly. A device containment housing may be coupled to a distal region of the shaft and may extend distally therefrom. The distal containment housing may be configured to accommodate at least a portion of the IMD therein. The IMD may, for example, be a leadless pacemaker, a lead, a neurostimulation device, a sensor or any other suitable IMD. A plurality of electrodes may be distributed about an exterior surface of the device containment housing such that at least some of the plurality of electrodes may be positioned to test a potential IMD deployment location before deploying the IMD.
    Type: Grant
    Filed: October 25, 2017
    Date of Patent: September 1, 2020
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Brendan Early Koop, Yinghong Yu, Qi An, Keith R. Maile, Pramodsingh Hirasingh Thakur, Bin Mi, Jeffrey E. Stahmann, Viktoria A. Averina, Krzysztof Z. Siejko, Michael J. Kane, Allan Charles Shuros, Arjun D. Sharma, Brian Soltis
  • Patent number: 10729898
    Abstract: An apparatus comprises a cardiac signal sensing circuit configured for coupling electrically to a plurality of electrodes and to sense intrinsic cardiac activation at three or more locations within a subject's body using the electrodes; a stimulus circuit configured for coupling to the plurality of electrodes; a signal processing circuit electrically coupled to the cardiac signal sensing circuit and configured to determine a baseline intrinsic activation vector according to the sensed intrinsic cardiac activation; and a control circuit electrically coupled to the cardiac signal sensing circuit and stimulus circuit and configured to: initiate delivery of electrical pacing therapy using initial pacing parameters determined according to the baseline intrinsic activation vector; initiate sensing of a paced activation vector; and adjust one or more pacing therapy parameters according to the paced activation vector.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: August 4, 2020
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Allan Charles Shuros, Yinghong Yu, David J. Ternes, Michael J. Kane, William J. Linder
  • Patent number: 10688304
    Abstract: A leadless cardiac pacemaker (LCP) is configured to sense cardiac activity and to pace a patient's heart and is disposable within a ventricle of the patient's heart. The LCP may include a housing, a first electrode and a second electrode that are secured relative to the housing and are spaced apart. A controller is disposed within the housing and is operably coupled to the first electrode and the second electrode such that the controller is capable of receiving, via the first electrode and the second electrode, electrical cardiac signals of the heart. The LCP may include a pressure sensor and/or an accelerometer. The controller may determine an atrial contraction timing fiducial based at least in part upon two or more of a signal from the pressure sensor, a signal from the accelerometer representing, and an electrical cardiac signal.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: June 23, 2020
    Assignee: CARDIAC PACEMAKERS, INC.
    Inventors: Qi An, Pramodsingh Hirasingh Thakur, Yinghong Yu, Michael J. Kane, Jeffrey E. Stahmann, Keith R. Maile
  • Publication number: 20200188677
    Abstract: Systems and methods for monitoring and treating patients with heart failure are discussed. The system can store in a memory stimulation parameters, including stimulation timing parameters for a plurality of heart rate ranges. The system includes a plurality of timers with respective durations for the plurality of heart rate ranges. A stimulation control circuit can identify a target heart range in which a detected heart rate falls, and measure an atrioventricular (AV) conduction characteristic value in response to the timer for the target heart range being expired at the detected heart rate. The stimulation control circuit can update a stimulation parameter corresponding to the target heart rate range using the measured AV conduction characteristic. The updated stimulation parameter can be used in cardiac stimulation.
    Type: Application
    Filed: November 25, 2019
    Publication date: June 18, 2020
    Inventors: Qi An, Yinghong Yu, Adam MacEwen
  • Publication number: 20200188674
    Abstract: Systems and methods for monitoring and treating patients with heart failure are discussed. The system may receive patient atrioventricular (AV) conduction characteristic under different heart rates or patient conditions. Stimulation parameters including stimulation timing parameters may be stored in a memory. The system may include a stimulation control circuit configured to determine a parameter update schedule indicating a timing at which to update stimulation parameter using patient AV conduction characteristic, and dynamically update at least a portion of the stored set of stimulation parameters at the determined parameter update schedule. For a specified heart rate or heart rate range, a stimulation parameter may be selected from the set of the stimulation parameters for use during cardiac stimulation.
    Type: Application
    Filed: November 25, 2019
    Publication date: June 18, 2020
    Inventors: Qi An, Yinghong Yu
  • Patent number: 10675472
    Abstract: Systems and methods for evaluating electrostimulation of a heart are disclosed. A system can comprise an electrostimulation circuit that can deliver multi-site electrostimulation, including pacing at two or more sites of the heart during the same cardiac cycle. The system can comprise a heart sound sensor circuit configured to sense a heart sound (HS) signal during multi-site stimulation. The heart sound sensor circuit can also sense HS signals in response to uni-site stimulation at a specified site capturing at least a portion of the heart. The system can comprise a pacing analyzer circuit that uses the HS signals during the multi-site stimulation and during the uni-site stimulation to determine a capture status indication that indicates whether the multi-site stimulation captures the two or more sites of the heart, and can be one of a full capture indication, a partial capture indication, or a loss of capture indication.
    Type: Grant
    Filed: October 15, 2015
    Date of Patent: June 9, 2020
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Qi An, Pramodsingh Hirasingh Thakur, Yinghong Yu
  • Publication number: 20200001092
    Abstract: An implantable medical device (IMD) that includes a housing, a first electrode secured relative to the housing, a second electrode secured relative to the housing, and a gyroscope secured relative to the housing. The IMD may include circuitry in the housing in communication with the first electrode, the second electrode, and the gyroscope. The circuitry may be configured to determine and store a plurality of torsion data measurements, from which a representation of a twist profile may be determined.
    Type: Application
    Filed: August 8, 2019
    Publication date: January 2, 2020
    Applicant: CARDIAC PACEMAKERS, INC.
    Inventors: Bin Mi, Pramodsingh Hirasingh Thakur, Jeffrey E. Stahmann, Keith R. Maile, Qi An, Brendan Early Koop, Yinghong Yu, Viktoria A. Averina, Michael J. Kane, Krzysztof Z. Siejko