Patents by Inventor Yinghong Yu
Yinghong Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10493285Abstract: Systems and methods for multi-site cardiac stimulation are disclosed. The system includes an electrostimulation circuit to deliver electrostimulation to one or more candidate sites of at least one heart chamber. The system may sense a physiological signal including during electrostimulation of the heart, use the physiological signal to determine a first stimulation vector for electrostimulation at a first left ventricular (LV) site and a second stimulation vector for electrostimulation at a different second LV site, and determine a therapy mode including a first chronological order and a first timing offset between stimulations delivered according to the first and second stimulation vectors. The electrostimulation circuit may deliver electrostimulation to the heart in accordance with the first and second stimulation vectors and the therapy mode.Type: GrantFiled: May 24, 2017Date of Patent: December 3, 2019Assignee: Cardiac Pacemakers, Inc.Inventors: Yinghong Yu, David J. Ternes, Keith L. Herrmann, Sunipa Saha, Pratik K. Pandya, Jason Humphrey, David L. Perschbacher
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Patent number: 10485978Abstract: An apparatus comprises a cardiac signal sensing circuit configured to sense a plurality of intrinsic cardiac signals using a plurality of cardiac pacing sites, a heart sound sensing circuit, a stimulus circuit configured to provide an electrical cardiac pacing stimulus to the plurality of pacing sites, and a control circuit electrically coupled to the cardiac signal sensing circuit and the stimulus circuit. The control circuit includes a pacing site locating circuit configured to generate an indication of a preferred pacing site as one of a) a subset of the respective cardiac pacing sites selected using the intrinsic ventricular activation time interval value, from which subset the preferred pacing site is selected using the heart sound characteristic value; or b) a subset of the respective cardiac pacing sites selected using the heart sound characteristic value, from which subset the preferred pacing site is selected using the ventricular activation time interval value.Type: GrantFiled: March 15, 2018Date of Patent: November 26, 2019Assignee: Cardiac Pacemakers, Inc.Inventors: Pramodsingh Hirasingh Thakur, Yinghong Yu, David L. Perschbacher
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Publication number: 20190351233Abstract: Some systems and methods may facilitate selection of a vector for delivering electrical stimulation to a patient's heart. One method may include displaying a plurality of vectors on a display screen wherein each vector represents a different combination of three or more electro-stimulation electrodes, determining an electrical impedance for each of the plurality of vectors, displaying on the display screen the electrical impedance for each of the plurality of vectors, receiving a selection of a set of the plurality of vectors, determining, for each of the vectors in the set of vectors, a capture threshold, displaying on the display screen the capture threshold for each of the vectors in the set of vectors, receiving a selection of a vector from the set of vectors for delivery of electrical stimulation to the patient's heart, and programming the electro-stimulation device electrical stimulation to the patient's heart via the selected vector.Type: ApplicationFiled: July 30, 2019Publication date: November 21, 2019Inventors: Holly E. Rockweiler, Sunipa Saha, Keith L. Herrmann, Yinghong Yu, Joel A. Krueger
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Patent number: 10478124Abstract: This document discusses, among other things, using a pressure sensor to detect body sound information of a patient, such as cardiac murmurs, respiratory sounds, etc.Type: GrantFiled: July 20, 2017Date of Patent: November 19, 2019Assignee: Cardiac Pacemakers, Inc.Inventors: Qi An, Yinghong Yu, Jeffrey E. Stahmann, Pramodsingh Hirasingh Thakur, Michael J. Kane
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Patent number: 10478629Abstract: A leadless cardiac pacemaker (LCP) configured to sense cardiac activity and to pace a patient's heart. The LCP may include a housing, a first electrode secured relative to the housing, a second electrode secured relative to the housing, and a pressure sensor secured relative to the housing and coupled to the environment outside of the housing. The LCP may further include circuitry in the housing in communication with the first electrode, the second electrode, and the pressure sensor. The circuitry may be configured to determine and store a plurality of impedance-pressure data pairs, from which a representation of a pressure-volume loop may be determined.Type: GrantFiled: June 22, 2017Date of Patent: November 19, 2019Assignee: CARDIAC PACEMAKERS, INC.Inventors: Qi An, Pramodsingh Hirasingh Thakur, Yinghong Yu, Jeffrey E. Stahmann, Michael J. Kane
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Patent number: 10463305Abstract: Methods, systems and devices for providing cardiac resynchronization therapy (CRT) to a patient using a leadless cardiac pacemaker (LCP) and an extracardiac device (ED). The system is configured to identify atrial events to use as timing markers for the LCP to deliver CRT, and further to determine whether the timing markers are incorrectly sensed and to make adjustment or call for re-initialization as needed.Type: GrantFiled: October 25, 2017Date of Patent: November 5, 2019Assignee: CARDIAC PACEMAKERS, INC.Inventors: Qi An, Pramodsingh Hirasingh Thakur, Stephen J. Hahn, Yinghong Yu, Krzysztof Z. Siejko, Viktoria A. Averina, Brendan Early Koop, Keith R. Maile, Bin Mi
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Patent number: 10441795Abstract: Systems and methods for providing CRT therapy to a patient with an implanted multi-site pacing medical device. In one example, an intrinsic electrical delay associated with each of two or more left ventricle electrodes may be determined. The intrinsic electrical delay associated with each of the two or more left ventricle electrodes may be compared to an electrical delay threshold. If the electrical delay associated with one or fewer left ventricle electrodes is greater than the electrical delay threshold, a single left ventricle electrode may be selected for use during subsequent CRT therapy. If the electrical delay associated with more than one left ventricle electrode is greater than the electrical delay threshold, two or more of the left ventricle electrodes may be selected for use during subsequent CRT therapy.Type: GrantFiled: January 4, 2018Date of Patent: October 15, 2019Assignee: Cardiac Pacemakers, Inc.Inventors: Yinghong Yu, Keith L. Herrmann, Holly E. Rockweiler, Sunipa Saha, Benjamin J Nyquist
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Patent number: 10434318Abstract: Some systems and methods may facilitate selection of a vector for delivering electrical stimulation to a patient's heart. One method may include displaying a plurality of vectors on a display screen wherein each vector represents a different combination of three or more electro-stimulation electrodes, determining an electrical impedance for each of the plurality of vectors, displaying on the display screen the electrical impedance for each of the plurality of vectors, receiving a selection of a set of the plurality of vectors, determining, for each of the vectors in the set of vectors, a capture threshold, displaying on the display screen the capture threshold for each of the vectors in the set of vectors, receiving a selection of a vector from the set of vectors for delivery of electrical stimulation to the patient's heart, and programming the electro-stimulation device electrical stimulation to the patient's heart via the selected vector.Type: GrantFiled: December 18, 2014Date of Patent: October 8, 2019Assignee: Cardiac Pacemakers, Inc.Inventors: Holly E. Rockweiler, Sunipa Saha, Keith L. Herrmann, Yinghong Yu, Joel A. Krueger
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Patent number: 10426962Abstract: Methods, devices, and systems for performing pacing capture verification in implantable medical devices such as a leadless cardiac pacemakers using a pressure signal. An example medical device includes a pressure sensor and is configured to monitor for an evoked capture response using the pressure sensor following pace delivery. Various factors of the pressure waveform may be used including the use of threshold, templating, and slope, as well as comparing cross-domain sensed events including using a fiducial point from the pressure signal for comparison to an acoustic, electrical, or motion event, or the use of data obtained from a second device which may be implanted, wearable, or external to the patient.Type: GrantFiled: June 28, 2017Date of Patent: October 1, 2019Assignee: CARDIAC PACEMAKERS, INC.Inventors: Qi An, Jeffrey E. Stahmann, Pramodsingh Hirasingh Thakur, Yinghong Yu, Michael J. Kane
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Patent number: 10413733Abstract: An implantable medical device (IMD) that includes a housing, a first electrode secured relative to the housing, a second electrode secured relative to the housing, and a gyroscope secured relative to the housing. The IMD may include circuitry in the housing in communication with the first electrode, the second electrode, and the gyroscope. The circuitry may be configured to determine and store a plurality of torsion data measurements, from which a representation of a twist profile may be determined.Type: GrantFiled: October 23, 2017Date of Patent: September 17, 2019Assignee: CARDIAC PACEMAKERS, INC.Inventors: Bin Mi, Pramodsingh Hirasingh Thakur, Jeffrey E. Stahmann, Keith R. Maile, Qi An, Brendan Early Koop, Yinghong Yu, Viktoria A. Averina, Michael J. Kane, Krzysztof Z. Siejko
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Publication number: 20190275338Abstract: Devices and methods for improving device therapy such as cardiac resynchronization therapy by determining a value for a device parameter are described. An ambulatory medical device (AMD) can include a sensor circuit to sense a physiological signal and generate two or more signal metrics, and detect an event of worsening cardiac condition using the two or more signal metrics. In response to the detection of worsening cardiac condition, the AMD can determine, for a stimulator, a value of at least one stimulation parameter based on temporal responses of two or more signal metrics. The temporal responses include near-term and long-term responses to the stimulation. The AMD can program the stimulator with the determined parameter value, and generate stimulation according to the determined parameter value to stimulate target tissue.Type: ApplicationFiled: May 30, 2019Publication date: September 12, 2019Inventors: Qi An, Julie A. Thompson, Yinghong Yu, Yi Zhang, Pramodsingh Hirasingh Thakur
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Publication number: 20190217097Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods for pacing a HIS bundle of a patient. The apparatuses, systems, and methods may include applying stimulation energy through one or more of a plurality of electrodes to direct a stimulation locus and pace a HIS bundle of a patient.Type: ApplicationFiled: January 17, 2019Publication date: July 18, 2019Inventors: Pramodsingh H. Thakur, Allan C. Shuros, Brian Soltis, Juan G. Hincapie, Qi An, Yinghong Yu, Keith R. Maile
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Patent number: 10350418Abstract: Devices and methods for improving device therapy such as cardiac resynchronization therapy by determining a value for a device parameter are described. An ambulatory medical device (AMD) can include a sensor circuit to sense a physiological signal and generate two or more signal metrics, and detect an event of worsening cardiac condition using the two or more signal metrics. In response to the detection of worsening cardiac condition, the AMD can determine, for a stimulator, a value of at least one stimulation parameter based on temporal responses of two or more signal metrics. The temporal responses include near-term and long-term responses to the stimulation. The AMD can program the stimulator with the determined parameter value, and generate stimulation according to the determined parameter value to stimulate target tissue.Type: GrantFiled: October 26, 2016Date of Patent: July 16, 2019Assignee: Cardiac Pacemakers, Inc.Inventors: Qi An, Julie A. Thompson, Yinghong Yu, Yi Zhang, Pramodsingh Hirasingh Thakur
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Publication number: 20190083789Abstract: Systems and methods for managing heart failure are described. The system receives physiological information including a first HS signal corresponding to paced ventricular contractions and a second HS signal corresponding to intrinsic ventricular contractions. The system detects worsening heart failure (WHF) using the received physiological information. A signal analyzer circuit can generate a paced HS metric from the first HS signal and a sensed HS metric from the second HS signal, and determine a concordance indicator between the paced and the sensed HS metrics. In response to the detected WHF, the system can use the concordance indicator to generate a therapy adjustment indicator for adjusting electrostimulation therapy, or a worsening cardiac contractility indicator indicating the detected WHF is attributed to degrading myocardial contractility.Type: ApplicationFiled: August 28, 2018Publication date: March 21, 2019Inventors: Pramodsingh Hirasingh Thakur, Jason Humphrey, David J. Ternes, Qi An, Krzysztof Z. Siejko, Michael James Dufresne, Yinghong Yu
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Publication number: 20190076655Abstract: Systems and methods for selecting one or more sites at or within at least one heart chamber for cardiac stimulation are disclosed. The system can include a physiologic sensor circuit to sense physiologic signals at two or more candidate stimulation sites. The system can generate respective activation timing indicators corresponding to the two or more candidate stimulation sites, and detect MI indicators indicating the presence of, or spatial proximity of each of the two or more candidate stimulation sites to a MI tissue. The system can use the activation timing indicators and the MI indicators to select at least one target stimulation site or to determine an electrostimulation vector. The system can display the selected target stimulation site to a user, or deliver electrostimulation to the patient at the target stimulation site or according to the determined electrostimulation vector.Type: ApplicationFiled: November 14, 2018Publication date: March 14, 2019Inventors: Yinghong Yu, Martin McDaniel, Jason Humphrey, Qi An
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Patent number: 10195442Abstract: Systems and methods for determining multiple sites for multi-site cardiac stimulation are disclosed. The system can comprise an electrostimulation circuit that can deliver electrostimulation to one or more candidate sites in at least one chamber of the heart, such as a left ventricle of the heart, within the same cardiac cycle. The system can sense a physiologic signal during the electrostimulation of the heart, determine activation timings from first and second sets of physiologic signals respectively sensed at the plurality of candidate sites when the heart undergoes specified intrinsic activities or stimulation, and determine at least first and second selected sites, among a plurality of candidate sites, using the respective activation timings. The system can deliver multi-site stimulation such as to the first and second selected sites during a same cardiac cycle, simultaneously or separated by a specified temporal offset.Type: GrantFiled: March 18, 2016Date of Patent: February 5, 2019Assignee: Cardiac Pacemakers, Inc.Inventors: Yinghong Yu, Qi An, Pramodsingh Hirasingh Thakur
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Patent number: 10183169Abstract: Systems and methods may facilitate selection of a vector for delivering electrical stimulation to a patient's heart. One illustrative method may include delivering electrical stimulation at a first voltage to each vector in a first set of two or more vectors of a multi-vector medical system, determining whether the delivered electrical stimulation at the first voltage resulted in capture for each of the vectors in the first set of two or more vectors, identifying those vectors of the first set of two or more vectors that were determined to result in capture as a second set of vectors, delivering electrical stimulation at a second voltage that is lower than the first voltage to each vector in the second set of vectors, and determining whether the delivered electrical stimulation at the second voltage resulted in capture for each of the vectors in the second set of vectors.Type: GrantFiled: March 9, 2017Date of Patent: January 22, 2019Assignee: Cardiac Pacemakers, Inc.Inventors: Holly E. Rockweiler, Sunipa Saha, Keith L. Herrmann, Yinghong Yu, Joel A. Krueger
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Publication number: 20180361161Abstract: Systems and methods for monitoring and treating patients with heart failure (HF) are discussed. The system may sense cardiac signals, and receives information about patient physiological or functional conditions. A stimulation parameter table that includes recommended values of atrioventricular delay (AVD) or other timing parameters maybe created at a multitude of patient physiological or functional conditions. The system may periodically reassess patient physiological or functional conditions. A therapy programmer circuit may dynamically switch between left ventricular-only pacing and biventricular pacing, or switch between single site pacing and multisite pacing based on the patient condition. The therapy programmer circuit may adjust AVD and other timing parameters using the cardiac signal input and the stored stimulation parameter table. A HF therapy may be delivered according to the determined stimulation site, stimulation mode, and the stimulation timing.Type: ApplicationFiled: June 13, 2018Publication date: December 20, 2018Inventors: David J. Ternes, Yinghong Yu, Jason Humphrey, David L. Perschbacher, Michael James Dufresne, Adam MacEwen, Keith L. Herrmann
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Publication number: 20180361150Abstract: Systems and methods for monitoring and treating patients with heart failure (HF) are discussed. The system may sense cardiac signals, and receives information about patient physiological or functional conditions. A stimulation parameter table that includes recommended values of atrioventricular delay (AVD) or other timing parameters maybe created at a multitude of patient physiological or functional conditions. The system may periodically reassess patient physiological or functional conditions. A therapy programmer circuit may dynamically switch between left ventricular-only pacing and biventricular pacing, or switch between single site pacing and multisite pacing based on the patient condition. The therapy programmer circuit may adjust AVD and other timing parameters using the cardiac signal input and the stored stimulation parameter table. A HF therapy may be delivered according to the determined stimulation site, stimulation mode, and the stimulation timing.Type: ApplicationFiled: June 13, 2018Publication date: December 20, 2018Inventors: David J. Ternes, Yinghong Yu, Jason Humphrey, David L. Perschbacher, Michael James Dufresne, Adam MacEwen, Keith L. Herrmann
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Publication number: 20180361162Abstract: Systems and methods for monitoring and treating patients with heart failure (HF) are discussed. The system may sense cardiac signals, and receives information about patient physiological or functional conditions. A stimulation parameter table that includes recommended values of atrioventricular delay (AVD) or other timing parameters maybe created at a multitude of patient physiological or functional conditions. The system may periodically reassess patient physiological or functional conditions. A therapy programmer circuit may dynamically switch between left ventricular-only pacing and biventricular pacing, or switch between single site pacing and multisite pacing based on the patient condition. The therapy programmer circuit may adjust AVD and other timing parameters using the cardiac signal input and the stored stimulation parameter table. A HF therapy may be delivered according to the determined stimulation site, stimulation mode, and the stimulation timing.Type: ApplicationFiled: June 13, 2018Publication date: December 20, 2018Inventors: David J. Ternes, Yinghong Yu, Jason Humphrey, David L. Perschbacher, Michael James Dufresne, Adam MacEwen, Keith L. Herrmann