Patents by Inventor Yiwen Tang

Yiwen Tang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Coating Comprising An Elastin-Based Copolymer
    Publication number: 20120263759
    Abstract: A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided. The copolymer may be used as a coating on a stent. Methods of using a stent coated with the copolymer are also provided.
    Type: Application
    Filed: September 2, 2011
    Publication date: October 18, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Syed F.A. Hossainy, Yiwen Tang, Lothar W. Kleiner
  • Methods for fabricating coatings for drug delivery devices having gradient of hydration
    Patent number: 8277926
    Abstract: A method for fabricating a coating for an implantable medical device is provided comprising applying a first polymer on at least a portion of the device to form a first layer of the coating and applying a second polymer on at least a portion of the first layer to form a second layer of the coating. The second polymer has a lower degree of hydration than the first polymer.
    Type: Grant
    Filed: January 18, 2008
    Date of Patent: October 2, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Syed F. A. Hossainy, Yiwen Tang, Andrew C. Tung, Thierry Glauser
  • DRUG ELUTING IMPLANTABLE MEDICAL DEVICE WITH HEMOCOMPATIBLE AND/OR PROHEALING TOPCOAT
    Publication number: 20120209371
    Abstract: The present invention relates to implantable medical devices coated with polymer having hemocompatible and/or prohealing moieties appended thereto and to their use in the treatment of vascular diseases.
    Type: Application
    Filed: April 23, 2012
    Publication date: August 16, 2012
    Applicant: Abbott Cardiovasular Systems Inc.
    Inventors: Lothar W. Kleiner, Yiwen Tang
  • DRUG ELUTING IMPLANTABLE MEDICAL DEVICE WITH HEMOCOMPATIBLE AND/OR PROHEALING TOPCOAT
    Publication number: 20120209372
    Abstract: The present invention relates to implantable medical devices coated with polymer having hemocompatible and/or prohealing moieties appended thereto and to their use in the treatment of vascular diseases.
    Type: Application
    Filed: April 23, 2012
    Publication date: August 16, 2012
    Applicant: Abbott Cardiovasular Systems Inc.
    Inventors: Lothar W. Kleiner, Yiwen Tang
  • Coatings for drug delivery devices having gradient of hydration
    Patent number: 8231962
    Abstract: A coating for an implantable medical device is provided comprising a first layer including a first polymer and a second layer including a second polymer. The second layer is disposed over at least a portion of the first layer. The second polymer has a lower degree of hydration than the first polymer.
    Type: Grant
    Filed: January 18, 2008
    Date of Patent: July 31, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Syed F. A. Hossainy, Yiwen Tang, Andrew C. Tung, Thierry Glauser
  • Coatings for implantable devices including biologically erodable polyesters and methods for fabricating the same
    Patent number: 8192752
    Abstract: A medical article comprising an implantable substrate having a coating is disclosed, the coating comprising a biologically erodable polymer having the glass transition temperature below about ?50° C. The biologically erodable polymer can be blended with a polymeric additive which either has the glass transition temperature of about ?50° C. or higher, or a degree of crystallinity greater than that of the first polymer.
    Type: Grant
    Filed: November 21, 2003
    Date of Patent: June 5, 2012
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Yiwen Tang, Stephen D. Pacetti
  • Drug eluting implantable medical device with hemocompatible and/or prohealing topcoat
    Patent number: 8182829
    Abstract: The present invention relates to implantable medical devices coated with polymer having hemocompatible and/or prohealing moieties appended thereto and to their use in the treatment of vascular diseases.
    Type: Grant
    Filed: July 27, 2007
    Date of Patent: May 22, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Lothar W. Kleiner, Yiwen Tang
  • Coating Comprising An Elastin-Based Copolymer
    Publication number: 20120046640
    Abstract: The present invention is directed to medical devices including coatings. The coatings include a topcoat which includes a copolymer comprising a block of an elastin pentapeptide. The topcoat is over a layer of poly(vinyl alcohol) on a hydrophobic coating or over a porous coating comprising pores or depots that include a bioactive agent.
    Type: Application
    Filed: September 2, 2011
    Publication date: February 23, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Syed F.A. Hossainy, Yiwen Tang, Lothar W. Kleiner
  • DETECTION AND CHARACTERIZATION OF LASER-INDUCED HEAT AFFECTED ZONES ON POLYMER BASED DEVICES
    Publication number: 20110302677
    Abstract: Detection and characterization of laser-induced heat affected zones on polymer based devices, such as polymeric stents, are described where Nano Thermal Analysis may be used with atomic force microscopy to obtain the thermal behavior of materials with a spatial resolution of under, e.g., 100 nm. Heat may be applied locally to the measured polymeric stem via a probe tip and the resulting thermal-mechanical response can be measured.
    Type: Application
    Filed: June 3, 2011
    Publication date: December 8, 2011
    Applicant: Amaranth Medical Pte
    Inventors: Kamal RAMZIPOOR, Yiwen TANG
  • Methods for fabricating coatings for drug delivery devices having gradient of hydration
    Patent number: 8052988
    Abstract: A method for fabricating a coating for an implantable medical device is provided comprising applying a first polymer on at least a portion of the device to form a first layer of the coating and applying a second polymer on at least a portion of the first layer to form a second layer of the coating. The second polymer has a higher degree of hydration than the first polymer. The first or second polymer can comprise a polyorthoester.
    Type: Grant
    Filed: January 18, 2008
    Date of Patent: November 8, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Syed F. A. Hossainy, Yiwen Tang, Andrew C. Tung, Thierry Glauser
  • Medical device coated with a coating containing elastin pentapeptide VGVPG
    Patent number: 8029816
    Abstract: The present invention is directed to medical devices including coatings. The coatings include a topcoat which includes a copolymer comprising a block of an elastin pentapeptide. The topcoat is over a layer of poly(vinyl alcohol) on a hydrophobic coating or over a porous coating comprising pores or depots that include a bioactive agent.
    Type: Grant
    Filed: May 10, 2007
    Date of Patent: October 4, 2011
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Syed Faiyaz Ahmed Hossainy, Yiwen Tang, Lothar W. Kleiner
  • Drug-delivery stent formulations for restenosis and vulnerable plaque
    Patent number: 8017140
    Abstract: Drug-delivery stents capable of providing release of two or more drugs such as everolimus and estradiol are provided. The stents can be used for treating a disease such as restenosis and vulnerable plaque.
    Type: Grant
    Filed: May 21, 2007
    Date of Patent: September 13, 2011
    Assignee: Advanced Cardiovascular System, Inc.
    Inventors: Syed Faiyaz Ahmed Hossainy, Gordon Stewart, Deborah Kilpatrick, Jeffrey Ellis, Gene Park, Gina Zhang, Paul Consigny, Yiwen Tang
  • Biologically absorbable coatings for implantable devices and methods for fabricating the same
    Patent number: 8003123
    Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising a biologically degradable, biologically erodable, and/or biologically resorbable ABA or AB block copolymer. A biologically active agent can be conjugated to the block copolymer.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: August 23, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Eugene T. Michal, Yiwen Tang
  • Purification of polymers for coating applications
    Patent number: 7985441
    Abstract: Various embodiments of methods and devices for coating stents are described herein. Among these embodiments are methods of manufacturing an implantable medical device by purifying a polymer with a fluid capable of swelling the polymer, and subsequently coating a device with the purified polymer or fabricating a device from the purified polymer. A preferred polymer is poly(vinylidene fluoride-co-hexafluoropropylene).
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: July 26, 2011
    Inventors: Yiwen Tang, Stephen D. Pacetti, Qing Lin, Ni Ding
  • BIOLOGICALLY ABSORBABLE COATINGS FOR IMPLANTABLE DEVICES AND METHODS FOR FABRICATING THE SAME
    Publication number: 20110117161
    Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising a biologically degradable, biologically erodable, and/or biologically resorbable ABA or AB block copolymer. A biologically active agent can be conjugated to the block copolymer.
    Type: Application
    Filed: May 5, 2008
    Publication date: May 19, 2011
    Inventors: Syed F.A. Hossainy, Eugene T. Michal, Yiwen Tang
  • COATINGS FOR IMPLANTABLE MEDICAL DEVICES COMPRISING HYDROPHILIC SUBSTANCES AND METHODS FOR FABRICATING THE SAME
    Publication number: 20110033517
    Abstract: A segmented polyurethane and an amphiphilic random or block copolymer are disclosed. The segmented polyurethane and the amphiphilic random or block copolymer can be used for fabricating a coating for an implantable medical device such as a stent.
    Type: Application
    Filed: October 21, 2010
    Publication date: February 10, 2011
    Inventors: Thierry Glauser, Connie S. Kwok, Charles D. Claude, Eugene T. Michal, Yiwen Tang, Irina Astafieva, John Whatley, Stephen D. Pacetti, Ashok Shah
  • COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME
    Publication number: 20110027336
    Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid.
    Type: Application
    Filed: April 19, 2010
    Publication date: February 3, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Yiwen Tang, Eugene T. Michal, Thierry Glauser, Stephen D. Pacetti, Jessica DesNoyer
  • Thermal Treatment Of An Implantable Medical Device
    Publication number: 20110008529
    Abstract: A method of manufacturing an implantable medical device, such as a drug eluting stent, is disclosed. The method includes subjecting an implantable medical device that includes a polymer to a thermal condition. The thermal condition can result in reduction of the rate of release of an active agent from the device subsequent to the implantation of the device and/or improve the mechanical properties of a polymeric coating on the device.
    Type: Application
    Filed: September 16, 2010
    Publication date: January 13, 2011
    Applicant: ADVANCED CARDIOVASCULAR SYSTEMS, INC.
    Inventors: Syed F.A. Hossainy, Yiwen Tang, Manish Gada
  • Thermal Treatment Of An Implantable Medical Device
    Publication number: 20110001271
    Abstract: A method of manufacturing an implantable medical device, such as a drug eluting stent, is disclosed. The method includes subjecting an implantable medical device that includes a polymer to a thermal condition. The thermal condition can result in reduction of the rate of release of an active agent from the device subsequent to the implantation of the device and/or improve the mechanical properties of a polymeric coating on the device.
    Type: Application
    Filed: September 10, 2010
    Publication date: January 6, 2011
    Applicant: ADVANCED CARDIOVASCULAR SYSTEMS, INC.
    Inventors: Syed F. A. Hossainy, Yiwen Tang, Manish Gada
  • Thermal Treatment Of An Implantable Medical Device
    Publication number: 20110003068
    Abstract: A method of manufacturing an implantable medical device, such as a drug eluting stent, is disclosed. The method includes subjecting an implantable medical device that includes a polymer to a thermal condition. The thermal condition can result in reduction of the rate of release of an active agent from the device subsequent to the implantation of the device and/or improve the mechanical properties of a polymeric coating on the device.
    Type: Application
    Filed: September 15, 2010
    Publication date: January 6, 2011
    Applicant: ADVANCED CARDIOVASCULAR SYSTEMS, INC.
    Inventors: Syed F. A. Hossainy, Yiwen Tang, Manish Gada