Patents by Inventor Yiwen Tang

Yiwen Tang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Morphology profiles for control of agent release rates from polymer matrices
    Publication number: 20080124372
    Abstract: The present disclosure teaches methods of controlling the release rate of agents from a polymeric matrix that include designing and creating a predetermined initial morphology (IM) profile in a polymeric matrix. The teachings indicate, inter alia, that control over the release rate of agents can provide for an improved control over the administration of agents as well as have an effect upon the mechanical integrity and absorption rate of the polymeric matrix.
    Type: Application
    Filed: June 6, 2006
    Publication date: May 29, 2008
    Inventors: Syed F. A. Hossainy, Fuh-Wei Tang, Lothar Kleiner, Thierry Glauser, Yiwen Tang, Wouter Roorda, Stephen Pacetti, Gina Zhang, Yung-Ming Chen, Andrew F. McNiven, Sean A. McNiven, Brandon J. Yoe
  • Biologically absorbable coatings for implantable devices and methods for fabricating the same
    Patent number: 7378106
    Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising a biologically degradable, biologically erodable, and/or biologically resorbable ABA or AB block copolymer. A biologically active agent can be conjugated to the block copolymer.
    Type: Grant
    Filed: December 18, 2006
    Date of Patent: May 27, 2008
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Eugene T. Michal, Yiwen Tang
  • Stent Coatings comprising hydrophilic additives
    Publication number: 20080118543
    Abstract: A coating for implantable medical devices and a method for fabricating thereof are disclosed. The coating includes a mixture of a hydrophobic polymer and a polymeric hydrophilic additive, wherein the hydrophobic polymer and the hydrophilic additive form a physically entangled or interpenetrating system.
    Type: Application
    Filed: September 19, 2007
    Publication date: May 22, 2008
    Inventors: Stephen D. Pacetti, Yiwen Tang
  • Coatings For Drug Delivery Devices Having Gradient Of Hydration
    Publication number: 20080113207
    Abstract: A coating for an implantable medical device is provided comprising a first layer including a first polymer and a second layer including a second polymer. The second layer is disposed over at least a portion of the first layer. The second polymer has a lower degree of hydration than the first polymer.
    Type: Application
    Filed: January 18, 2008
    Publication date: May 15, 2008
    Inventors: Stephen Pacetti, Syed Hossainy, Yiwen Tang, Andrew Tung, Thierry Glauser
  • Coating comprising an elastin-based copolymer
    Publication number: 20080038310
    Abstract: A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided.
    Type: Application
    Filed: May 10, 2007
    Publication date: February 14, 2008
    Inventors: Syed Hossainy, Yiwen Tang, Lothar Kleiner
  • Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof
    Patent number: 7329413
    Abstract: Coatings for implantable medical devices, and methods for fabricating thereof, are provided. The coatings include a first polymer layer and a second polymer layer, where the second polymer has a higher degree of hydration than the first polymer.
    Type: Grant
    Filed: November 6, 2003
    Date of Patent: February 12, 2008
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Syed F. A. Hossainy, Yiwen Tang, Andrew C. Tung, Thierry Glauser
  • Stent coatings comprising hydrophilic additives
    Publication number: 20080021008
    Abstract: A coating for implantable medical devices and a method for fabricating thereof are disclosed. The coating includes a mixture of a hydrophobic polymer and a polymeric hydrophilic additive, wherein the hydrophobic polymer and the hydrophilic additive form a physically entangled or interpenetrating system.
    Type: Application
    Filed: September 19, 2007
    Publication date: January 24, 2008
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen Pacetti, Yiwen Tang
  • Polyactive/polylactic acid coatings for an implantable device
    Patent number: 7311980
    Abstract: A polymeric coating for a medical device that comprises poly(lactic acid) and a block copolymer including blocks of poly(ethylene glycol) and poly(butylene terephthalate) is provided.
    Type: Grant
    Filed: August 2, 2004
    Date of Patent: December 25, 2007
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Yiwen Tang, Gina Zhang
  • Solvent systems for coating medical devices
    Publication number: 20070286882
    Abstract: The present invention discloses a method of modulating drug release from a coating on a medical device, a medical device including a coating formed thereby, and a method of using the medical device for treating, preventing or ameliorating a medical condition.
    Type: Application
    Filed: June 9, 2006
    Publication date: December 13, 2007
    Inventors: Yiwen Tang, Gina Zhang
  • Elastin-based copolymers
    Publication number: 20070286885
    Abstract: A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided.
    Type: Application
    Filed: June 9, 2006
    Publication date: December 13, 2007
    Inventors: Syed F. A. Hossainy, Mikael Trollsas, Thierry Glauser, Yiwen Tang
  • Drug-delivery stent formulations for restenosis and vulnerable plaque
    Publication number: 20070269484
    Abstract: Drug-delivery stents capable of providing release of two or more drugs such as everolimus and estradiol are provided. The stents can be used for treating a disease such as restenosis and vulnerable plaque.
    Type: Application
    Filed: May 21, 2007
    Publication date: November 22, 2007
    Inventors: Syed Hossainy, Gordon Stewart, Deborah Kilpatrick, Jeffrey Ellis, Gene Park, Gina Zhang, Paul Consigny, Yiwen Tang
  • Stent coatings comprising hydrophilic additives
    Patent number: 7279174
    Abstract: A coating for implantable medical devices and a method for fabricating thereof are disclosed. The coating includes a mixture of a hydrophobic polymer and a polymeric hydrophilic additive, wherein the hydrophobic polymer and the hydrophilic additive form a physically entangled or interpenetrating system.
    Type: Grant
    Filed: May 8, 2003
    Date of Patent: October 9, 2007
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Yiwen Tang
  • Coatings formed from stimulus-sensitive material
    Publication number: 20070231363
    Abstract: A coating comprising a stimulus-responsive material and a bioactive agent for controlled release of the bioactive agent and methods of making and using the same are disclosed.
    Type: Application
    Filed: March 29, 2006
    Publication date: October 4, 2007
    Inventors: Yung-Ming Chen, Yiwen Tang, Stephen Pacetti, Lothar Kleiner
  • Coating for implantable medical devices
    Patent number: 7247364
    Abstract: An implantable medical device, such as a stent, is disclosed having a coating. The coating includes a poly(butylene terephthalate-co-ethylene glycol)polymer. The coating can also include a drug.
    Type: Grant
    Filed: February 25, 2005
    Date of Patent: July 24, 2007
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Yiwen Tang, Andrew C. Tung, Stephen D. Pacetti
  • Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same
    Publication number: 20070167602
    Abstract: Polymers containing polyesters and, optionally, agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate having a coating, and the coating contains a polymer comprising a polymeric product of a reaction comprising a polyol and a polycarboxylic acid.
    Type: Application
    Filed: March 21, 2007
    Publication date: July 19, 2007
    Inventors: Stephen Pacetti, Yiwen Tang
  • Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same
    Patent number: 7214759
    Abstract: Polymers containing polyesters and, optionally, agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate having a coating, and the coating contains a polymer comprising a polymeric product of a reaction comprising a polyol and a polycarboxylic acid.
    Type: Grant
    Filed: November 24, 2004
    Date of Patent: May 8, 2007
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Yiwen Tang
  • Biologically absorbable coatings for implantable devices and methods for fabricating the same
    Publication number: 20070098758
    Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising a biologically degradable, biologically erodable, and/or biologically resorbable ABA or AB block copolymer. A biologically active agent can be conjugated to the block copolymer.
    Type: Application
    Filed: December 18, 2006
    Publication date: May 3, 2007
    Inventors: Syed Hossainy, Eugene Michal, Yiwen Tang
  • Biologically absorbable coatings for implantable devices and methods for fabricating the same
    Patent number: 7169404
    Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising a biologically degradable, biologically erodable, and/or biologically resorbable ABA or AB block copolymer. A biologically active agent can be conjugated to the block copolymer.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: January 30, 2007
    Assignee: Advanced Cardiovasular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Eugene T. Michal, Yiwen Tang
  • Stent coating
    Patent number: 7063884
    Abstract: A stent comprising a coating layer is disclosed. The coating layer has a hydrophobic component and a hydrophilic component, wherein a region of the coating layer on or about the outermost surface of the coating layer has a higher content or concentration of the hydrophilic component than the hydrophobic component.
    Type: Grant
    Filed: February 22, 2005
    Date of Patent: June 20, 2006
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Yiwen Tang, Andrew C. Tung, Stephen D. Pacetti
  • Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same
    Publication number: 20060111546
    Abstract: Polymers containing polyesters and, optionally, agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate having a coating, and the coating contains a polymer comprising a polymeric product of a reaction comprising a polyol and a polycarboxylic acid.
    Type: Application
    Filed: November 24, 2004
    Publication date: May 25, 2006
    Inventors: Stephen Pacetti, Yiwen Tang