Patents by Inventor Yoichi Makino

Yoichi Makino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210387194
    Abstract: A microfluidic device including a substrate having at least one droplet holder formed thereon, and a cover member facing the substrate with a space between the cover member and the substrate, and having a flow path formed in the space and connected to the droplet holder. The flow path has a height of more than 0 ?m and 30 ?m or less.
    Type: Application
    Filed: August 27, 2021
    Publication date: December 16, 2021
    Applicant: TOPPAN PRINTING CO., LTD.
    Inventors: Keisuke GOTO, Yoichi MAKINO
  • Patent number: 11142731
    Abstract: An analytical device includes a plate including a first substrate having a front surface and a back surface and a second substrate facing the back surface of the first substrate such that at least one detection space observable from outside is formed between the second substrate and the back surface of the first substrate, and an adapter. The first substrate has a first port having a through hole formed through the front surface and communicated with the detection space for delivering a liquid-containing substance into the detection space, the first substrate has a second port having a through hole formed through the front surface and communicated with the detection space for discharging a liquid-containing substance or a gas from the detection space, and the adapter is attachable to and detachable from the first port and the second port, and the front surface of the first substrate without the adapter is flat.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: October 12, 2021
    Assignee: TOPPAN PRINTING CO., LTD.
    Inventors: Tomoko Kunitomi, Yoichi Makino
  • Patent number: 11097269
    Abstract: A microfluidic device includes: a base plate allowing an electromagnetic wave to pass therethrough and having no autofluorescence; a microwell array formed on the base plate and including a wall layer in which a plurality of through-holes are formed in a thickness direction; and a lid member disposed opposite to the base plate in a state of being separated from the wall layer, wherein microwells are formed by the base plate and the through-holes formed in the wall layer, and wherein the wall layer is formed of a material containing a colored component that absorbs an electromagnetic wave of a predetermined wavelength.
    Type: Grant
    Filed: April 4, 2018
    Date of Patent: August 24, 2021
    Assignee: TOPPAN PRINTING CO., LTD.
    Inventors: Keisuke Goto, Yoichi Makino, Akihiro Hoshino
  • Patent number: 10894973
    Abstract: An array device including a base having wells, a cover positioned over the base with a gap from the base such that openings of the wells are covered by the cover with the gap in between, an injection port communicating with the gap, a discharge port communicating with the gap and positioned apart from the injection port, and a waste liquid vessel which collects liquid that flows from the gap via the discharge port and is positioned at a level different from the gap forming a channel. The discharge port is placed to discharge a surplus aqueous solution outside the wells from the discharge port by an oleaginous sealing liquid to be delivered from the injection port.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: January 19, 2021
    Assignee: TOPPAN PRINTING CO., LTD.
    Inventors: Yoichi Makino, Tomoyuki Ozawa, Shuichi Akashi, Tomoko Kunitomi
  • Patent number: 10766073
    Abstract: After a chuck portion chucks a workpiece holding body which aligns and holds a plurality of workpieces on which components are to be placed, the posture of the workpieces held in the workpiece holding body is adjusted due to rotation mechanism by rotating the chuck portion around an axial line which extends in an aligning direction of the plurality of workpieces held in the workpiece holding body. Then, a placing head places the components on each of the plurality of workpieces which are subjected to posture adjustment.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: September 8, 2020
    Assignee: PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD.
    Inventor: Yoichi Makino
  • Publication number: 20200270674
    Abstract: A method for detecting a target molecule, including supplying a liquid dispersion of a structural substance including a target molecule into a well array such that the structural substance is introduced into wells of the well array, supplying a sealing solution into the well array such that a layer of the sealing solution is formed on the liquid dispersion in the wells, and that the liquid dispersion is sealed in the wells, extracting the target molecule from the structural substance, and detecting the target molecule.
    Type: Application
    Filed: May 12, 2020
    Publication date: August 27, 2020
    Applicant: TOPPAN PRINTING CO., LTD.
    Inventors: Takumi HIRASE, Yoichi MAKINO, Yosuke HORIUCHI
  • Patent number: 10718776
    Abstract: A method of detecting a biological substance, including introducing a first substance dispersed in a solvent into a flow channel formed between a first substrate and a second substrate such that the first substance is placed in a first well formed in the first substrate, and detecting the first substance. The first well is formed such that the first well has an open side which faces downwards and is communicated with the flow channel, and the solvent has a specific gravity larger than a specific gravity of the first substance.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: July 21, 2020
    Assignee: TOPPAN PRINTING CO., LTD.
    Inventor: Yoichi Makino
  • Publication number: 20200224253
    Abstract: A method of detecting a nucleic acid including mixing a fluid including a target nucleic acid with a detection reagent including a first enzyme for cleaving a first nucleic acid having a first flap and a second enzyme for cleaving a second nucleic acid such that the target nucleic acid, the first nucleic acid and the second nucleic acid form a complex as a first invasive structure, conducting a first reaction which causes the first enzyme to cleave the first flap of the first invasive structure and produces a third nucleic acid that forms a complex, as a second invasive structure, with a fourth nucleic acid having a second flap, and conducting a second reaction which causes the second enzyme to cleave the second flap of the second invasive structure and produces a cleaved product.
    Type: Application
    Filed: January 31, 2020
    Publication date: July 16, 2020
    Applicant: TOPPAN PRINTING CO., LTD.
    Inventors: Masayuki Ogino, Yoichi Makino
  • Patent number: 10668584
    Abstract: A plurality of workpieces on which components are to be placed are lined up in a row and held by a workpiece holding body, and the workpiece holding body is placed on a carrier and is transported to a working position using a transport conveyor. After the workpiece holding body is chucked by a chuck portion, the workpiece holding body is separated from the carrier by linking an operation of lifting and lowering the chuck portion using a lifting-lowering mechanism and an operation of moving the carrier in a transport direction. The chuck portion which chucks the workpiece holding body is rotated by a rotation mechanism, postures of the plurality of workpieces which are held in the workpiece holding body are adjusted, and then, the components are placed on component placing parts using a placing head.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: June 2, 2020
    Assignee: PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD.
    Inventor: Yoichi Makino
  • Patent number: 10661401
    Abstract: When a workpiece holder holding a workpiece is rocked around a lateral rocking axis by a work stage of a mounter and the workpiece is positioned so that one mounting surface of the workpiece faces a predetermined direction to be worked, a component is mounted on the one mounting surface by a mounting head of the mounter. When a posture of the workpiece in the workpiece holder is changed by a posture changing head of a posture changer and thereafter the workpiece holder in which the posture of the workpiece is changed is rocked around the lateral rocking axis by the work stage of the mounter and the workpiece is positioned so that the other mounting surface of the workpiece faces a predetermined direction to be worked, a component is mounted on the other mounting surface by the mounting head of the mounter.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: May 26, 2020
    Assignee: PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD.
    Inventors: Seiji Mizuoka, Takahiro Endo, Yasuhiro Suzuki, Yoichi Makino
  • Patent number: 10627327
    Abstract: A membrane vesicle recovery device includes: a liquid filler; and at least a fused membrane having a lipid bilayer membrane which covers at least a part of the outer periphery of the liquid filler, in which a content of a membrane vesicle is mixed into the liquid filler through fusing of the membrane vesicle and the fused membrane.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: April 21, 2020
    Assignee: TOPPAN PRINTING CO., LTD.
    Inventors: Yoichi Makino, Shinji Irie
  • Publication number: 20200003691
    Abstract: A device including a well array including wells in which a target substance is detected based on a biochemical reaction thereof. Each of the wells has an aspect ratio of 1 or more as calculated by Formula (1) such that the biochemical reaction of the target substance is detected, Aspect ratio=Depth of each well/Diameter of largest circle among circles included in a region enclosed by a rim of each well??Formula (1).
    Type: Application
    Filed: September 13, 2019
    Publication date: January 2, 2020
    Applicant: TOPPAN PRINTING CO., LTD.
    Inventors: Misaki NAGAHARA, Yoichi MAKINO, Akihiro HOSHINO, Takumi HIRASE, Tomoko KUNITOMI, Keisuke GOTO, Yusuke HORIUCHI
  • Publication number: 20190241948
    Abstract: A biomolecule analysis method including: feeding a reagent into a reaction container which includes a plurality of wells and filing the reagent in the plurality of wells, the reagent being for causing an enzymatic reaction with regard to a target substance of analysis; feeding an oil sealing solution over the plurality of wells and sealing the reagent into the plurality of wells with the oil sealing solution so that the plurality of wells become a plurality of independent reaction containers; performing the enzymatic reaction by incubating the reaction container; and detecting a signal amplified by the enzymatic reaction.
    Type: Application
    Filed: April 17, 2019
    Publication date: August 8, 2019
    Applicant: TOPPAN PRINTING CO., LTD.
    Inventors: Yoichi Makino, Tomoko Kunitomi
  • Publication number: 20190085385
    Abstract: A method of detecting a target molecule including binding, to first target molecules, specific binding substances which are capable of recognizing different epitopes and labeled with nucleic acid fragments, respectively, detecting the specific binding substances based on fluorescence signals of different fluorescence wavelengths from the nucleic acid fragments, and detecting the first target molecules based on the fluorescence signals that correspond to the specific binding substances, respectively.
    Type: Application
    Filed: November 19, 2018
    Publication date: March 21, 2019
    Applicant: TOPPAN PRINTING CO., LTD.
    Inventors: Yoichi Makino, Takumi Hirase, Noriaki Arai, Hiroyuki Noji
  • Publication number: 20190060897
    Abstract: An analysis apparatus including a stage, an analysis device placed on the stage and including receiving sections which accommodate a sample and a reagent for biochemical reaction, and are communicated with one another through a flow path having an inlet and an outlet, a liquid introduction section which is connected to the inlet and supplies into the flow path the sample, the reagent, and an sealing liquid for sealing each of the receiving sections, and a waste liquid storage section which is connected to the outlet and stores as waste liquid an excess of the sample and the reagent and a part of the sealing liquid supplied to the flow path, an optical system which includes an objective lens, emits excitation light to the receiving sections and allows observation of fluorescence generated in the receiving sections by the excitation light, and a control unit that controls such that the sealing liquid and the excess of the sample and the reagent form an interface in the waste liquid storage section, and that the
    Type: Application
    Filed: October 29, 2018
    Publication date: February 28, 2019
    Applicant: TOPPAN PRINTING CO., LTD.
    Inventors: Yoichi MAKINO, Akihiro HOSHINO, Tomoko KUNITOMI, Keisuke GOTO, Yosuke HORIUCHI
  • Publication number: 20190062821
    Abstract: A reaction container including a transparent base having a first surface having at least one region where recessed portions are formed and recessed from the first surface, and a cover member positioned such that the cover member forms a gap from the first surface inside the region and is welded to the transparent base outside the region. The cover member absorbs infrared light and transmits light having a wavelength within a range of visible light.
    Type: Application
    Filed: October 26, 2018
    Publication date: February 28, 2019
    Applicant: TOPPAN PRINTING CO., LTD.
    Inventors: Masahiro MATSUKAWA, Yoichi MAKINO, Akihiro HOSHINO
  • Patent number: 10165716
    Abstract: A substrate conveyance mechanism that includes conveyance units and a working area length change part to easily change the types of substrates to allow substrates of different lengths to be selected to mount electronic components onto the substrate. The conveyance units include a working area for substrates having different length that are conveyed from a stand-by area, an area length of the working area that is variable in accordance with the length of the substrate, and a stand-by unit corresponding to a stand-by area for the substrate to be carried in to the working area. The working area length change part changes an interval between a commonly used first pulley and one of a plurality of second pulleys selectively used in accordance with the area length of the working area by changing a belt winding path of a conveyance belt wound on the pulleys in the working unit.
    Type: Grant
    Filed: March 3, 2014
    Date of Patent: December 25, 2018
    Assignee: PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD.
    Inventors: Toshihiko Nagaya, Hiroyuki Fujiwara, Shigeo Ogata, Yoshinori Konda, Yoichi Makino, Shinji Yamamoto, Shuuichi Kubota, Kimio Iizuka, Koji Sakurai
  • Publication number: 20180299380
    Abstract: A microfluidic device includes a substrate having an electromagnetic wave transmission property, a lid member facing the substrate and being separated from the substrate such that a flow channel is formed between the substrate and the lid member, a light absorption layer which is placed in the flow channel and absorbs an electromagnetic wave, and a microwell array formed on the substrate and having plural microwells that are open to the flow channel to receive a target of analysis.
    Type: Application
    Filed: June 26, 2018
    Publication date: October 18, 2018
    Applicant: Toppan Printing Co., Ltd.
    Inventors: Yoichi Makino, Keisuke Goto
  • Publication number: 20180243869
    Abstract: When a workpiece holder holding a workpiece is rocked around a lateral rocking axis by a work stage of a mounter and the workpiece is positioned so that one mounting surface of the workpiece faces a predetermined direction to be worked, a component is mounted on the one mounting surface by a mounting head of the mounter. When a posture of the workpiece in the workpiece holder is changed by a posture changing head of a posture changer and thereafter the workpiece holder in which the posture of the workpiece is changed is rocked around the lateral rocking axis by the work stage of the mounter and the workpiece is positioned so that the other mounting surface of the workpiece faces a predetermined direction to be worked, a component is mounted on the other mounting surface by the mounting head of the mounter.
    Type: Application
    Filed: February 5, 2018
    Publication date: August 30, 2018
    Inventors: SEIJI MIZUOKA, TAKAHIRO ENDO, YASUHIRO SUZUKI, YOICHI MAKINO
  • Publication number: 20180221877
    Abstract: A microfluidic device includes: a base plate allowing an electromagnetic wave to pass therethrough and having no autofluorescence; a microwell array formed on the base plate and including a wall layer in which a plurality of through-holes are formed in a thickness direction; and a lid member disposed opposite to the base plate in a state of being separated from the wall layer, wherein microwells are formed by the base plate and the through-holes formed in the wall layer, and wherein the wall layer is formed of a material containing a colored component that absorbs an electromagnetic wave of a predetermined wavelength.
    Type: Application
    Filed: April 4, 2018
    Publication date: August 9, 2018
    Applicant: TOPPAN PRINTING CO., LTD.
    Inventors: Keisuke Goto, Yoichi Makino, Akihiro Hoshino