Abstract: An electrostatic induction generator includes a housing, a first board fixed to the housing, and a second board arranged in parallel to the first board to be able move relative to it, in which electrostatic induction generator, counter electrodes are placed at a first facing surface of the first board, electrically charged films are placed at every other constant interval at a second facing surface of the second board so as to face the counter electrodes, the counter electrodes are comprised of pluralities of first electrodes and second electrodes provided separated from each other at the first facing surface, first electrodes and second electrodes are alternately arranged at constant intervals in a single line, a plurality of lines of single lines of the first electrodes and second electrodes are provided at the first facing surface, and the constant intervals of the plurality of lines respectively differ in phase.

Abstract: Patients with ErbB2-overexpressing cancers can be given an ErbB2 targeting agent as a therapeutic regimen but not all patients are responsive. The present invention concerns the diagnostic, prognostic and therapeutic methods and compositions for evaluating potential efficacy of an ErbB2 targeting agent in ErbB2-overexpressing cancers by evaluating PTEN expression, which is predictive of responsiveness or resistance to ErbB2 targeting agents such as trastuzumab. Low PTEN expression is predictive of a patient who will respond poorly to trastuzumab.

Abstract: Patients with ErbB2-overexpressing cancers can be given an ErbB2 targeting agent as a therapeutic regimen but not all patients are responsive. The present invention concerns the diagnostic, prognostic and therapeutic methods and compositions for evaluating potential efficacy of an ErbB2 targeting agent in an ErbB2-overexpressing cancers by evaluating PTEN expression, which is predictive of responsiveness or resistance to ErbB2 targeting agents such as trastuzumab. Low PTEN expression is predictive of a patient who will respond poorly to trastuzumab.

Abstract: To achieve an effective gas filtering in a plasma spectrometric apparatus using a gas of a comparatively high consumption flow rate, and to improve the analytical ability, there is provided a plasma spectrometric apparatus containing a sample introducer for producing and delivering an injector gas containing an analyte sample, a plasma generator for generating plasma into which the injector gas is introduced, and an analyzer disposed subsequent to the plasma generator for analyzing the analyte sample. The plasma spectrometric apparatus contains a first gas line for supplying gas to the sample introducer, a second gas line for supplying gas to the plasma generator, and a filter located in the first gas line for removing impurities contained in the gas.

Abstract: An electrostatic induction generator includes a housing, a first board fixed to the housing, and a second board arranged in parallel to the first board to be able move relative to it, in which electrostatic induction generator, counter electrodes are placed at a first facing surface of the first board, electrically charged films are placed at every other constant interval at a second facing surface of the second board so as to face the counter electrodes, the counter electrodes are comprised of pluralities of first electrodes and second electrodes provided separated from each other at the first facing surface, first electrodes and second electrodes are alternately arranged at constant intervals in a single line, a plurality of lines of single lines of the first electrodes and second electrodes are provided at the first facing surface, and the constant intervals of the plurality of lines respectively differ in phase.

Abstract: To achieve an effective gas filtering in a plasma spectrometric apparatus using a gas of a comparatively high consumption flow rate, and to improve the analytical ability, there is provided a plasma spectrometric apparatus containing a sample introducer for producing and delivering an injector gas containing an analyte sample, a plasma generator for generating plasma into which the injector gas is introduced, and an analyzer disposed subsequent to the plasma generator for analyzing the analyte sample. The plasma spectrometric apparatus contains a first gas line for supplying gas to the sample introducer, a second gas line for supplying gas to the plasma generator, and a filter located in the first gas line for removing impurities contained in the gas.

Abstract: Provided is a technology capable of preventing arithmetic operation accuracy from deteriorating even when a bipolar transistor used to form a Gilbert multiplier core has poor characteristics. A correction current generating circuit (3) uses a constant current source (301) to feed a constant current I0 to an emitter of a bipolar transistor (Q7) being a first replica transistor having the same current gain ? as bipolar transistors (Q1 to Q4) that form the Gilbert multiplier core (101), to generate a current of ?·I0 on a collector side thereof. The current is output as a correction current ?·I0, and is added to each of one of input signals (±K1·Vy) of the Gilbert multiplier core (101) as a bias current, to thereby eliminate influence of the current gain ? on an output signal being a multiplication result.

Abstract: Patients with ErbB2-overexpressing cancers can be given an ErbB2 targeting agent as a therapeutic regimen but not all patients are responsive. The present invention concerns the diagnostic, prognostic and therapeutic methods and compositions for evaluating potential efficacy of an ErbB2 targeting agent in an ErbB2-overexpressing cancers by evaluating PTEN expression, which is predictive of responsiveness or resistance to ErbB2 targeting agents such as trastuzumab. Low PTEN expression is predictive of a patient who will respond poorly to trastuzumab.

Abstract: Provided is a technology capable of preventing arithmetic operation accuracy from deteriorating even when a bipolar transistor used to form a Gilbert multiplier core has poor characteristics. A correction current generating circuit (3) uses a constant current source (301) to feed a constant current I0 to an emitter of a bipolar transistor (Q7) being a first replica transistor having the same current gain ? as bipolar transistors (Q1 to Q4) that form the Gilbert multiplier core (101), to generate a current of ?·I0 on a collector side thereof. The current is output as a correction current ?·I0, and is added to each of one of input signals (±K1·Vy) of the Gilbert multiplier core (101) as a bias current, to thereby eliminate influence of the current gain ? on an output signal being a multiplication result.

Abstract: The invention is directed to the provision of a physical quantity sensor that can suppress noise caused by external vibrations, while also suppressing variations in output signal caused by variations in reference voltage. The physical quantity sensor includes an oscillator which converts an externally applied physical quantity into an electrical signal, a reference signal generating circuit which outputs a reference signal; an oscillator circuit which causes the oscillator to oscillate by applying an oscillator signal produced based on the reference signal, and a detector circuit which detects an output signal of the oscillator by multiplying the output signal by the oscillator signal and dividing the reference signal.

Abstract: A physical quantity sensor includes a sensor element that converts an externally applied physical quantity to an electrical signal; a detection circuit that amplifies and detects the output signal of this sensor element; and an adjustment circuit that adjusts the output signal from the detection circuit to a predetermined signal by applying the power supply wherein the adjustment circuit comprises an amplifier circuit that amplifies the output signal from the detection circuit and a reference amplifier circuit that has a gain that is made to correspond to the gain of the amplifier circuit. This configuration allows the gain of the amplifier circuit in the adjustment circuit to be varied according to the power supply voltage and, as a results, provides a physical quantity sensor having reliable sensor detection sensitivity and high-accuracy ratiometric characteristics.

Abstract: Patients with ErbB2-overexpressing cancers can be given an ErbB2 targeting agent as a therapeutic regimen but not all patients are responsive. The present invention concerns the diagnostic, prognostic and therapeutic methods and compositions for evaluating potential efficacy of an ErbB2 targeting agent in an ErbB2-overexpressing cancers by evaluating PTEN expression, which is predictive of responsiveness or resistance to ErbB2 targeting agents such as trastuzumab. Low PTEN expression is predictive of a patient who will respond poorly to trastuzumab.

Abstract: A physical quantity sensor 1 comprises a driving circuit 4 that drives a sensor element based on a reference signal; the sensor element 3 that is driven by the driving circuit 4 to convert an externally applied physical quantity to an electrical signal; and an amplifier circuit 5 that amplifies an output signal of the sensor element 3. The driving circuit 4 controls a driving signal, which drives the sensor element, based on the reference signal so that the driving signal is at a fixed level, and the amplifier circuit 5 has a gain characteristic that amplifies the output signal in a direction reverse to a direction in which the reference signal varies or the driving signal of the driving circuit varies. This configuration allows the physical quantity sensor to reduce output level variations in the sensor output against signal level variations in the reference signal and to make the sensitivity constant.

Abstract: A vibration body for angular speed sensor has a vibrator that includes vibration pieces, a supporting part for supporting the vibration pieces, and a mounting substrate for mounting the vibrator. The mounting substrate has a seat part for fixing the supporting part and supporting the vibrator and a base part. The seat part has a level difference representing a predetermined height from the base part. The predetermined height is set larger than an oscillation width of the vibration pieces. The seat part also has an edge portion that has a shape of a curved line, and each line in a direction perpendicular to each position on the edge portion determines a mounting angle for mounting the vibrator and has an angle in the same direction as a reference direction defined in the mounting substrate or in a direction at least one being different from it.

Abstract: Patients with ErbB2-overexpressing cancers can be given an ErbB2 targeting agent as a therapeutic regimen but not all patients are responsive. The present invention concerns the diagnostic, prognostic and therapeutic methods and compositions for evaluating potential efficacy of an ErbB2 targeting agent in an ErbB2-overexpressing cancers by evaluating PTEN expression, which is predictive of responsiveness or resistance to ErbB2 targeting agents such as trastuzumab. Low PTEN expression is predictive of a patient who will respond poorly to trastuzumab.

Abstract: Patients with ErbB2-overexpressing cancers can be given an ErbB2 targeting agent as a therapeutic regimen but not all patients are responsive. The present invention concerns the diagnostic, prognostic and therapeutic methods and compositions for evaluating potential efficacy of an ErbB2 targeting agent in an ErbB2-overexpressing cancers by evaluating PTEN expression, which is predictive of responsiveness or resistance to ErbB2 targeting agents such as trastuzumab. Low PTEN expression is predictive of a patient who will respond poorly to trastuzumab.

Abstract: A physical quantity sensor comprises a sensor circuit that converts an externally applied physical quantity to an electrical signal and outputs a detection signal; an adjustment circuit that adjusts the detection signal, which is received from the sensor circuit, to a predetermined signal; and an output circuit that forms an output signal from the signal of the adjustment circuit wherein the sensor circuit and the output circuit are driven by a common power supply voltage. The adjustment circuit comprises a pulse generation circuit that generates a pulse modulation signal based on the power supply voltage; and an amplifier circuit that amplifies the detection signal, which is received from the sensor circuit, with a gain made variable by the pulse modulation signal, wherein the detection sensitivity of the output signal is made variable according to the power supply voltage.

Abstract: The invention provides a rechargeable electronic timepiece that restarts the operation of a clock circuit by inputting a power source, thereby securely confirming the clock operation. The electronic timepiece includes a first power source (2), a clock circuit (8) connected to the first power source, a power source input detecting circuit (86) for detecting an input of a second power source (3), a switch circuit (7, 9) for connecting the first power source and the second power source, and a control circuit (87) for controlling the switch circuit to connect the first power source and the second power source so that the first power source is charged by the second power source thereby operating the clock circuit when the power source input detecting circuit detects an input of the second power source.

Abstract: A physical quantity sensor includes a sensor element for converting a physical quantity applied from outside into an electric signal, a detection circuit for amplifying and detecting an output signal of the sensor element, and an adjusting circuit for adjusting the output signal from the detection circuit to a predetermined signal. The adjusting circuit has an amplifying circuit for amplifying the output signal from the detection circuit and a reference amplification circuit having an amplification ratio linked with the amplifying circuit. With this configuration, it is possible to change the amplification ratio of the amplifying circuit provided in the adjusting circuit in accordance with a power voltage. As a result, it is possible to realize a physical quantity sensor having stable sensor detection sensitivity and highly accurate ratiometric characteristic.

Abstract: A physical quantity sensor 1 comprises a driving circuit 4 that drives a sensor element based on a reference signal; the sensor element 3 that is driven by the driving circuit 4 to convert an externally applied physical quantity to an electrical signal; and an amplifier circuit 5 that amplifies an output signal of the sensor element 3. The driving circuit 4 controls a driving signal, which drives the sensor element, based on the reference signal so that the driving signal is at a fixed level, and the amplifier circuit 5 has a gain characteristic that amplifies the output signal in a direction reverse to a direction in which the reference signal varies or the driving signal of the driving circuit varies. This configuration allows the physical quantity sensor to reduce output level variations in the sensor output against signal level variations in the reference signal and to make the sensitivity constant.