Patents by Inventor Yong A. Yu

Yong A. Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Remote-controlled mobile machine using flexible shafts
    Patent number: 8335597
    Abstract: A remote-controlled mobile machine has a pair of flexible shafts (10) formed by inserting torque transmission driving wires (11) into tubes (12). One ends of the flexible shafts (10) are respectively connected to power sources (2), and the other ends thereof are respectively connected to a pair of left and right crawler mechanisms (102). The crawler mechanisms (102) are driven/controlled by remote control via the flexible shafts (10) to make the mobile machine travel.
    Type: Grant
    Filed: September 8, 2006
    Date of Patent: December 18, 2012
    Assignee: Kagoshima University
    Inventors: Ryota Hayashi, Showzou Tsujio, Yong Yu
  • Method for forming stair-step structures
    Patent number: 8329051
    Abstract: A method for forming a stair-step structure in a substrate is provided. An organic mask is formed over the substrate. A hardmask with a top layer and sidewall layer is formed over the organic mask. The sidewall layer of the hard mask is removed while leaving the top layer of the hardmask. The organic mask is trimmed. The substrate is etched. The forming the hardmask, removing the sidewall layer, trimming the organic mask, and etching the substrate are repeated a plurality of times.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: December 11, 2012
    Assignee: Lam Research Corporation
    Inventors: Qian Fu, Hyun-Yong Yu
  • Clonal strains of attenuated vaccinia viruses and methods of use thereof
    Publication number: 20120308484
    Abstract: Clonal strains of vaccinia viruses are provided. Also provided are methods of identifying and isolating attenuated and oncolytic clonal strains from virus preparations. Modified recombinant forms of the clonal strains also are provided. The clonal strains and virus preparations can be used for diagnostic and therapeutic methods, in particular for therapy and diagnosis or monitoring treatment of proliferative disorders, including neoplastic diseases, such as, but are not limited to, solid tumors and blood cancers.
    Type: Application
    Filed: April 13, 2012
    Publication date: December 6, 2012
    Inventors: Aladar A. Szalay, Nanhai G. Chen, Yong A. Yu, Qian Zhang
  • Microorganisms for therapy
    Patent number: 8323959
    Abstract: Therapeutic methods and microorganisms therefor are provided. The microorganisms are designed to accumulate in immunoprivileged tissues and cells, such as in tumors and other proliferating tissue and in inflamed tissues, compared to other tissues, cells and organs, so that they exhibit relatively low toxicity to host organisms. The microorganisms also are designed or modified to result in leaky cell membranes of cells in which they accumulate, resulting in production of antibodies reactive against proteins and other cellular products and also permitting exploitation of proferating proliferating tissues, particularly tumors, to produce selected proteins and other products. Vaccines containing the microorganisms are provided. Combinations of the microorganisms and anti-cancer agents and uses thereof for treating cancer also are provided.
    Type: Grant
    Filed: April 17, 2008
    Date of Patent: December 4, 2012
    Assignee: Genelux Corporation
    Inventors: Aladar A. Szalay, Tatyana Timiryasova, Yong A. Yu, Qian Zhang
  • METHOD OF FABRICATION OF NANO PARTICLE COMPLEX CATALYST BY PLASMA ION IMPLANTATION AND DEVICE FOR THE SAME
    Publication number: 20120289397
    Abstract: Provided is a method of fabricating a nano particle complex catalyst including generating a plasma ion of a solid element and performing plasma ion implantation to carry a catalyst component of the solid element in a porous carrier. In the method, a pulse direct current voltage is applied to the deposition source to generate the plasma ion of the solid element, and a synchronized voltage is applied to the porous carrier, thereby instantly applying a pulse high voltage to the solid element. The ionized solid element is accelerated toward the porous carrier by the pulse high voltage instantly applied to the solid element, thereby performing the ion implantation.
    Type: Application
    Filed: November 3, 2011
    Publication date: November 15, 2012
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Ji Young BYUN, Seung Hee HAN, Heon Phil HA, Byung Yong YU, Sang Hoon KIM, Do Hyung KIM, Chae Sun LIM
  • Photomasks, methods of exposing a substrate to light, methods of forming a pattern, and methods of manufacturing a semiconductor device
    Patent number: 8304173
    Abstract: The method of forming a pattern includes forming a first photosensitive layer pattern including a first pattern in a first region of a substrate and a second pattern in a second region of the substrate, by performing a first photolithography process using a photomask having a first mask region and a second mask region. The first pattern is transferred from the first mask region, and the second pattern is transferred from the second mask region. The method further includes forming a second photosensitive layer pattern including a third pattern in the second region of the substrate and a fourth pattern in the first region of the substrate, by performing a second photolithography process using the photomask. The third pattern is transferred from the first mask region, and the fourth pattern is transferred from the second mask region.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: November 6, 2012
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Sang-Yong Yu, Sung-Hyuck Kim, Gi-Sung Yoon
  • Microorganisms for therapy
    Publication number: 20120276010
    Abstract: Therapeutic methods and vaccinia virus therefor are provided. The viruses are designed so that they accumulate in immunoprivileged tissues and cells, such as in tumors and other proliferating tissue and in inflamed tissues, compared to other tissues, cells and organs, so that they exhibit relatively low toxicity to host organisms. Combinations of the viruses and anti-cancer agents and uses thereof for treating cancer also are provided.
    Type: Application
    Filed: July 10, 2012
    Publication date: November 1, 2012
    Inventors: Aladar A. Szalay, Tatyana Timiryasova, Yong A. Yu, Qian Zhang
  • Probing apparatus with on-probe device-mapping function
    Patent number: 8279451
    Abstract: One aspect of the present disclosure provides a probing apparatus with on-probe device-mapping function. A probing apparatus according to this aspect of the present disclosure comprises a housing, at least one probe stage positioned on the housing and configured to retain at least one probe, a device holder positioned in the housing and configured to receive at least one semiconductor device under test, and an inspection module having a predetermined field of view configured to capture an image showing at least the semiconductor device, wherein the probe stage includes a driving unit configured to move the probe out of focus of the inspection module in a mapping phase while keeping the device under test in the field of view of the optical inspection module.
    Type: Grant
    Filed: June 9, 2010
    Date of Patent: October 2, 2012
    Assignee: Star Technologies Inc.
    Inventors: Yong Yu Liu, Choon Leong Lou, Lai Peng Chew
  • Microorganisms for imaging and/or treatment of tumors
    Publication number: 20120244068
    Abstract: Modified viruses encoding transporter proteins and methods for preparing the modified viruses are provided. Vaccines that contain the viruses are provided. The viruses also can be used in diagnostic methods, such detection and imaging of tumors. The viruses also can be used in methods of treatment of diseases, such as proliferative and inflammatory disorders, including as anti-tumor agents.
    Type: Application
    Filed: May 10, 2012
    Publication date: September 27, 2012
    Inventors: Nanhai Chen, Aladar A. Szalay, Yong A. Yu, Qian Zhang, Yuman Fong
  • LUMINOGEN COMPOUNDS AND THE USE OF THE SAME FOR BIOSENSING AND CELLULAR IMAGING
    Publication number: 20120237964
    Abstract: Provided herein are a luminogen compound of formula (I) including a AIE luminophore moiety conjugated with a maleimide moiety and a use of the same for detecting thiol groups in biomolecules. Also provided is a dye molecule, a biosensor or a bioprobe comprising the luminogen compound of formula (I) in use for detecting thiol groups in biomolecules. The detection method of the present subject matter not only has high thio-selectivity and sensitivity, but also is rapid, convenient and handy.
    Type: Application
    Filed: March 16, 2012
    Publication date: September 20, 2012
    Applicant: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Benzhong TANG, Yang Liu, Wing Yip Lam, Yong Yu
  • Microorganisms for therapy
    Patent number: 8221769
    Abstract: Therapeutic methods and microorganisms therefor are provided. The microorganisms are designed to accumulate in immunoprivileged tissues and cells, such as in tumors and other proliferating tissue and in inflamed tissues, compared to other tissues, cells and organs, so that they exhibit relatively low toxicity to host organisms. The microorganisms also are designed or modified to result in leaky cell membranes of cells in which they accumulate, resulting in production of antibodies reactive against proteins and other cellular products and also permitting exploitation of proferating proliferating tissues, particularly tumors, to produce selected proteins and other products. Vaccines containing the microorganisms are provided. Combinations of the microorganisms and anti-cancer agents and uses thereof for treating cancer also are provided.
    Type: Grant
    Filed: October 26, 2009
    Date of Patent: July 17, 2012
    Assignee: Genelux Corporation
    Inventors: Aladar A. Szalay, Tatyana Timiryasova, Yong A. Yu, Qian Zhang
  • METHOD FOR FORMING STAIR-STEP STRUCTURES
    Publication number: 20120149203
    Abstract: A method for forming a stair-step structure in a substrate is provided. An organic mask is formed over the substrate. A hardmask with a top layer and sidewall layer is formed over the organic mask. The sidewall layer of the hard mask is removed while leaving the top layer of the hardmask. The organic mask is trimmed. The hardmask is removed. The substrate is etched. The forming the hardmask, removing the sidewall layer, trimming the organic mask, and etching the substrate are repeated a plurality of times.
    Type: Application
    Filed: July 19, 2011
    Publication date: June 14, 2012
    Applicant: LAM RESEARCH CORPORATION
    Inventors: Qian Fu, Ce Qin, Hyun-Yong Yu
  • METHOD FOR FORMING STAIR-STEP STRUCTURES
    Publication number: 20120149201
    Abstract: A method for forming a stair-step structure in a substrate is provided. An organic mask is formed over the substrate. A hardmask with a top layer and sidewall layer is formed over the organic mask. The sidewall layer of the hard mask is removed while leaving the top layer of the hardmask. The organic mask is trimmed. The substrate is etched. The forming the hardmask, removing the sidewall layer, trimming the organic mask, and etching the substrate are repeated a plurality of times.
    Type: Application
    Filed: December 14, 2010
    Publication date: June 14, 2012
    Applicant: LAM RESEARCH CORPORATION
    Inventors: Qian Fu, Hyun-Yong Yu
  • Light emitting microorganisms and cells for diagnosis and therapy of diseases associated with wounded or inflamed tissue
    Patent number: 8137904
    Abstract: Described is the use of a microorganism or cell containing a DNA sequence encoding a detectable protein or a protein capable of inducing a detectable signal, e.g., a luminescent or fluorescent protein for the preparation of a diagnostic composition for diagnosis and/or visualization of wounded or inflamed tissue or a disease associated therewith. Moreover, therapeutic uses are described, wherein the microorganism or cell additionally contain an expressible DNA sequence encoding a protein suitable for therapy, e.g. an enzyme causing cell death or digestion of debris.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: March 20, 2012
    Assignee: Genelux Corporation
    Inventors: Aladar A. Szalay, Shahrokh Shabahang, Yong A. Yu
  • Probing Apparatus with On-Probe Device-Mapping Function
    Publication number: 20110304857
    Abstract: One aspect of the present disclosure provides a probing apparatus with on-probe device-mapping function. A probing apparatus according to this aspect of the present disclosure comprises a housing, at least one probe stage positioned on the housing and configured to retain at least one probe, a device holder positioned in the housing and configured to receive at least one semiconductor device under test, and an inspection module having a predetermined field of view configured to capture an image showing at least the semiconductor device, wherein the probe stage includes a driving unit configured to move the probe out of focus of the inspection module in a mapping phase while keeping the device under test in the field of view of the optical inspection module.
    Type: Application
    Filed: June 9, 2010
    Publication date: December 15, 2011
    Applicant: STAR TECHNOLOGIES INC.
    Inventors: Yong Yu Liu, Choon Leong Lou, Lai Peng Chew
  • Microorganisms for therapy
    Publication number: 20110300176
    Abstract: Therapeutic methods and microorganisms therefor are provided. The microorganisms are designed to accumulate in immunoprivileged tissues and cells, such as in tumors and other proliferating tissue and in inflamed tissues, compared to other tissues, cells and organs, so that they exhibit relatively low toxicity to host organisms. The microorganisms also are designed or modified to result in leaky cell membranes of cells in which they accumulate, resulting in production of antibodies reactive against proteins and other cellular products and also permitting exploitation of proferating proliferating tissues, particularly tumors, to produce selected proteins and other products. Vaccines containing the microorganisms are provided. Combinations of the microorganisms and anti-cancer agents and uses thereof for treating cancer also are provided.
    Type: Application
    Filed: April 17, 2008
    Publication date: December 8, 2011
    Inventors: Aladar A. Szalay, Tatyana Timiryasova, Yong A. Yu, Qian Zhang
  • Modified vaccinia virus strains for use in diagnostic and therapeutic methods
    Publication number: 20110293527
    Abstract: Modified viruses and methods for preparing the modified viruses are provided. Vaccines that contain the viruses are provided. The viruses can be used in methods of treatment of diseases, such as proliferative and inflammatory disorders, including cancer, and as anti-tumor and/or antiangiogenic agents. The viruses also can be used in diagnostic methods.
    Type: Application
    Filed: August 2, 2011
    Publication date: December 1, 2011
    Inventors: Nanhai Chen, Alexa Frentzen, Aladar A. Szalay, Yong A. Yu, Qian Zhang
  • Modified vaccinia virus strains for use in diagnostic and therapeutic methods
    Patent number: 8066984
    Abstract: Modified viruses and methods for preparing the modified viruses are provided. Vaccines that contain the viruses are provided. The viruses can be used in methods of treatment of diseases, such as proliferative and inflammatory disorders, including cancer, and as anti-tumor and/or antiangiogenic agents. The viruses also can be used in diagnostic methods.
    Type: Grant
    Filed: April 4, 2008
    Date of Patent: November 29, 2011
    Assignee: Genelux Corporation
    Inventors: Aladar A. Szalay, Alexa Frentzen, Yong A. Yu, Nanhai Chen, Qian Zhang
  • Modified vaccinia virus strains for use in diagnostic and therapeutic methods
    Patent number: 8052968
    Abstract: Modified viruses and methods for preparing the modified viruses are provided. Vaccines that contain the viruses are provided. The viruses can be used in methods of treatment of diseases, such as proliferative and inflammatory disorders, including as anti-tumor agents. The viruses also can be used in diagnostic methods.
    Type: Grant
    Filed: October 16, 2007
    Date of Patent: November 8, 2011
    Assignee: Genelux Corporation
    Inventors: Nanhai Chen, Alexa Frentzen, Aladar A. Szalay, Yong A. Yu, Qian Zhang
  • Rotational stage for high speed, large area scanning in focused beam systems
    Patent number: RE43757
    Abstract: A mechanical scanning stage for high speed image acquisition in a focused beam system. The mechanical scanning stage preferably is a combination of four stages. A first stage provides linear motion. A second stage, above the first stage, provides rotational positioning. A third stage above the rotational stage is moveable in a first linear direction, and the fourth stage above the third stage is positionable in a second linear direction orthogonal to the first direction. The four stages are responsive to input from a controller programmed with a polar coordinate pixel addressing method, for positioning a specimen mounted on the mechanical stage to allow an applied static focus beam to irradiate selected areas of interest, thereby imaged by collecting signals from the specimen using a polar coordinate pixel addressing method.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: October 23, 2012
    Assignee: National University of Singapore
    Inventors: Yong Yu Liu, Daniel S. H. Chan, Jacob C. H. Phang