Abstract: The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts and esters thereof: which inhibit the Apoptosis signal-regulating kinase 1 (ASK-1), which is associated with autoimmune disorders, neurodegenerative disorders, inflammatory diseases, chronic kidney disease, cardiovascular disease. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from ASK-1 related disease. The invention also relates to methods of treating an ASK-1 related disease in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The present invention specifically relates to methods of treating ASK-1 associated with hepatic steatosis, including non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH).

Abstract: A light sensing device, according to an embodiment, for sensing light emitted from a light source, and reflected or scattered from an object comprises: a light transmitting member; and a light sensing unit disposed on the light transmitting member, wherein the light sensing unit comprises: a light transmitting region; a first electrode layer; a semiconductor layer; and a second electrode layer, wherein the semiconductor layer comprises: a first semiconductor layer disposed around the light-transmitting region; and a second semiconductor layer disposed outside the first semiconductor layer.

Abstract: A display driver includes: a compensator configured to divide an input image into a plurality of blocks having a plurality of columns and a plurality of rows, generate a first current map in which a current magnitude corresponding to each of the plurality of blocks has been calculated, generate a second current map based on a cumulative summation of the current magnitude of the block located on each column of the first current map in a column direction, and generate output data by compensating pixel values of the input image based on a third current map in which the current magnitude of the block located on each row of the second current map has been adjusted with respect to a position in a row direction; and a data driver configured to generate an output image based on the output data and provide the output image to a display panel.

Abstract: Provided is a deionization apparatus which includes: a porous electrode having fine pores; a non-pore ion exchange membrane that is formed in the porous electrode; a counter electrode that is spaced from the non-pore ion exchange membrane and faces the non-pore ion exchange membrane; and a spacer that is located between the porous electrode and the counter electrode, and that has a flow passage through which water to be treated passes.

Abstract: A lens assembly according to an embodiment includes a holder including a first sidewall having a first opening and a second sidewall having a second opening, a liquid lens unit including at least a portion disposed in the first opening and the second opening, and an adhesive member coupling the holder and the liquid lens unit, wherein the second opening faces the first opening in a direction perpendicular to an optical-axis of the liquid lens unit.

Abstract: An etching composition selectively removes a titanium nitride film from a stacked conductive film structure including a titanium nitride (TiN) film and a tantalum nitride (TaN) film. The etching composition configured to etch titanium nitride (TiN) includes 5 wt % to 30 wt % of hydrogen peroxide, 15 wt % to 50 wt % of acid compound, and 0.001 wt % to 5 wt % of corrosion inhibitor, with respect to a total weight of the etching composition, wherein the acid compound includes at least one of phosphoric acid (H3PO4), nitric acid (HNO3), hydrochloric acid (HCl), hydroiodic acid (HI), hydrobromic acid (HBr), perchloric acid (HClO4), silicic acid (H2SiO3), boric acid (H3BO3), acetic acid (CH3COOH), propionic acid (C2H5COOH), lactic acid (CH3CH(OH)COOH), and glycolic acid (HOCH2COOH).

Abstract: An artificial nail for attachment to a natural nail includes a nail body having a bottom surface sized and shaped to be attachable to the top surface of the natural nail, a pressure sensitive adhesive disposed on the bottom surface of the nail body and a releasable backing film covering the pressure sensitive adhesive, wherein the releasable backing film has indicia indicating a size of the nail body.

Abstract: A super wide angle zoom lens may include: a first lens having convex surfaces at an object side and an image side, and formed in a spherical shape; a second lens having a concave surface at the object side; a third lens having a convex surface at the image side; and a fourth lens having a convex surface at the object side and formed in a spherical shape, wherein the first to fourth lenses are sequentially arranged from the object side toward the image side.

Abstract: A simple and compact filtering dielectric resonator antenna comprising: a ground plane, a dielectric substrate defined on the ground plane, a dielectric resonator defined on the dielectric substrate, and a hybrid feeding line, the hybrid feeding line comprises: a microstrip line and a metallic conformal strip, and the microstrip line comprises: a microstrip main branch, a first microstrip stub and a second microstrip stub. In the present invention, a hybrid feeding line is firstly employed to a dielectric resonator antenna. It has been shown that this hybrid feeding line can not only increase the impedance bandwidth of the passband but also can introduce two radiation nulls right near the band edges. Both good filtering and radiating performances are therefore obtained without any extra filtering circuit, giving a very compact structure.

Abstract: A semiconductor memory device includes: a memory cell array including a plurality of memory cells; an error correction code (ECC) engine configured to detect and/or correct at least one error bit in read data and configured to generate a decoding status flag indicative of whether the at least one error bit is detected and/or corrected, wherein the read data is read from the memory cell array; a channel interface circuit configured to receive the read data and the decoding status flag from the ECC engine and configured to transmit the read data and the decoding status flag to a memory controller, wherein the channel interface circuit is configured to transmit the decoding status flag to the memory controller through a pin; and a control logic circuit configured to control the ECC engine and the channel interface circuit in response to an address and a command from the memory controller.

Abstract: Disclosed embodiments include vacuum electronics devices and methods of fabricating a vacuum electronics device. In a non-limiting embodiment, a vacuum electronics device includes: an electrode; a first film layer disposed on the electrode about a periphery of the electrode; and a second film layer disposed on the first film layer, the second film layer including a plurality of electrically conductive grid lines patterned therein that are supported only at the periphery of the electrode by the first film layer.

Abstract: The present disclosure relates to a protein having the activity of exporting O-acetylhomoserine and a novel modified protein thereof, a microorganism capable of producing O-acetylhomoserine with enhanced expression of the protein, and a method for producing O-acetylhomoserine using the microorganism.

Abstract: Various embodiments of the present invention relate to an electronic device and a method for delivering a message by the same. The electronic device may comprise: a camera; at least one processor functionally connected to the camera; and a memory for storing at least one program configured to be executable by the at least one processor, wherein the program comprises instructions configured to: capture an image of a sender by activating the camera in response to detection of a message input by the sender; analyze the captured image of the sender and the input message; determine a recipient and an output pattern on the basis of the result of the analysis; check whether the recipient is recognized; and when the recipient is recognized, deliver the message to the recognized recipient on the basis of the determined output pattern. Various other embodiments are possible.

Abstract: The present invention provides a chimeric antigen receptor and natural killer cells expressing the same, and particularly, a chimeric antigen receptor (CAR) which includes an intracellular signaling domain including the whole or a portion of an OX40 ligand (CD252), thereby having excellent effects of increasing anticancer activity of immune cells, and immune cells expressing the same.

Abstract: Provided is an electrode structure having a transparent electrode, a light blocking pattern provided on the transparent electrode, an auxiliary electrode pattern provided on the light blocking pattern, and an organic insulating pattern covering the light blocking pattern and the auxiliary electrode pattern, wherein a line width of the light blocking pattern is larger than a line width of the auxiliary electrode pattern. Also provided are an electronic device including the electrode structure, and a method of manufacturing the electrode structure.

Abstract: Provided is an electrode active material slurry including a clustered complex and a slurry, wherein the clustered complex includes an electrode active material, a solid electrolyte, a conductive material, and a first binder, and the slurry includes a solvent and a second binder. The electrode active material slurry may include the clustered complex including the first binder and the slurry including the second binder so as to decrease a surface area of the overall complex, such that adhesion property with the current collector may be sufficiently secured even by using a small amount of binder, and performance of the all-solid secondary battery may be further improved.

Abstract: Provided is yarn for a cell culture scaffold. The yarn for a cell culture scaffold according to an exemplary embodiment of the present invention includes slitting yarn produced by cutting a compressed nanofiber web to a predetermined width. Accordingly, by creating microenvironments suitable for migration, proliferation and differentiation of cells, cell viability may be enhanced and cells may be three-dimensionally proliferated. In addition, a scaffold according to the present invention has a mechanical strength sufficient for prevention of disruption of the scaffold which occurs during cell culture, such that cells may be stably proliferated. Further, the scaffold according to the present invention uses slitting yarn formed of the compressed nanofiber web, thereby having pores with various sizes, and therefore cell proliferation and cell viability may be enhanced by creation of an extracellular matrix-like environment.

Abstract: A sampling device includes a switch capacitor circuit. First ends of two switches are respectively connected to an input signal. Second end of the first switch is connected to an upper plate of a first capacitor. Second end of the second switch is connected to a lower plate of a second capacitor. A connection node connecting a lower plate of the first capacitor to an upper plate of the second capacitor is connected to a power source. The first ends of a third switch and a fourth switch are respectively connected to an input common-mode voltage. A second end of the third switch is connected to the upper plate of the first capacitor. A second end of the fourth switch is connected to the lower plate of the second capacitor. The connection node is connected to the power source. Thus, an output common-mode voltage of the sampling device is adjustable.

Abstract: A pinned memory space for caching data can be provided in a data node. The data that is cached in the pinned memory space can be prevented from being swapped out. A virtual address can be assigned to the data. The virtual address can be mapped to a memory address of the data in the pinned memory space for accessing the data by an application. A first command can be received from the application for caching the data. The first command can indicate an attribute associated with the caching of the data. Responsive to receiving the first command from the application for caching the data, the data associated with the first command can be cached by storing the attribute in association with the data in the pinned memory space.

Abstract: A computer-implemented method according to one embodiment includes creating, at a block storage system separate from a host system, a structural representation of image layer data utilized at the host system, mapping the structural representation created at the block storage system to the image layer data utilized at the host system, and performing one or more operations on the image layer data, utilizing the structural representation created at the block storage system.