Abstract: A semiconductor wafer according to an embodiment includes a monitoring pattern structure disposed over a substrate, a cover pattern layer covering portions of the monitoring pattern structure over the substrate, and contact patterns disposed over the cover pattern layer to extend over the cover pattern layer.

Abstract: Compositions and methods for editing, e.g., introducing double-stranded breaks, within the TTR gene are provided. Compositions and methods for treating subjects having amyloidosis associated with transthyretin (ATTR), are provided.

Abstract: In an embodiment, a semiconductor wafer includes an alignment key structure disposed over a substrate, a contact pattern layer disposed on the alignment key structure to extend upward of the alignment key structure, and an insulating layer in contact with the alignment key structure and the contact pattern layer over the substrate.

Abstract: An example system includes an electronic device and a server. The electronic device includes a display; a first communicator; and a first controller configured to: control to transmit, to the server, location data identifying locations of the electronic device. The server includes a second communicator; and a second controller configured to: control to receive the location data; identify a course of travel; link photograph images to locations on the course of travel; and control to transmit to the electronic device the course of travel and the photograph images. The first controller of the electronic device is configured to control to receive the course of travel and the photograph images and to control to display on the display, at the same time, a map image, the course of travel, and one or more of the photograph images linked to a selected location on the course of travel.

Abstract: A semiconductor wafer includes at least one chip region disposed in a substrate, a first chip guard disposed over the substrate in a chip sealing region positioned outside the at least one chip region, a second chip guard disposed over the substrate in a scribe lane region positioned outside the chip sealing region, and a test circuit pattern disposed in the scribe lane region and including a ground line electrically connected to a ground well in the substrate. The second chip guard includes a ground wiring layer electrically connected to the ground line of the test circuit pattern.

Abstract: A substrate treating apparatus and a substrate treating method are disclosed. The substrate treating apparatus includes a process module configured to perform processing on a substrate, an index module configured to insert the substrate into the process module and withdraw the substrate, of which the processing is completed, from the process module, a loading module configured to relay the substrate between the process module in a vacuum atmosphere and the index module in an atmospheric pressure atmosphere by switching an atmosphere thereof to the vacuum atmosphere or the atmospheric pressure atmosphere, and a control module configured to receive operation states from the process module, the index module, and the loading module and schedule operations of the process module, the index module, and the loading module in a direction in which the number of substrates to be processed per unit time increases with reference to the received operation states.

Abstract: An example system includes an electronic device and a server. The electronic device includes a display; a first communicator; and a first controller configured to: control to transmit, to the server, location data identifying locations of the electronic device. The server includes a second communicator; and a second controller configured to: control to receive the location data; identify a course of travel; link photograph images to locations on the course of travel; and control to transmit to the electronic device the course of travel and the photograph images. The first controller of the electronic device is configured to control to receive the course of travel and the photograph images and to control to display on the display, at the same time, a map image, the course of travel, and one or more of the photograph images linked to a selected location on the course of travel.

Abstract: The present invention discloses a varifocal laser processing system and method based on a variable light spot diffractive element. The system includes a laser device for generating a laser, a collimating lens for changing a light path and a diffractive optical element module for controlling light spot focal point distribution. The laser emitted by the laser device passes through the collimating lens to irradiate the diffractive optical element module, and the laser focused by the diffractive optical element module irradiates a to-be-processed workpiece; and the diffractive optical element module includes at least two DOE lenses oppositely distributed in an axial direction and a rotary actuator driving the DOE lenses to rotate. The rotary actuator drives at least one DOE lens to rotate with a central axis as a rotating center, thereby changing a position of a focal point generated after the laser is focused by the diffractive optical element module.

Abstract: In a crystal growth furnace having an array of vertically arranged heaters to provide controlled heating zones within a chamber, and a crucible for holding crystal material, wherein the crystal is grown vertically through the heating zones, the improvement includes a laser mounted outside the chamber which radiates a beam of energy to locally melt precipitates and inclusions. The furnace includes a mechanism to position the laser vertically to, at or near the interface between the formed crystal and crystal melt material above the formed crystal. The crystal material can be CdZnTe.

Abstract: An operation method of an application system includes receiving a chat room-entry event notifying that a user enters the chat room from a terminal in which an application is installed, generating an entry trigger based on the chat room enter event, and providing user context suitable information inferred based on a user key included in the entry trigger to the chat room.

Abstract: A method of hybridizing an FPA having an IR component and a ROIC component and interconnects between the two components, includes the steps of: providing an IR detector array and a Si ROIC; depositing a dielectric layer on both the IR detector array and on the Si ROIC; patterning the dielectric on both components to create openings to expose contact areas on each of the IR detector array and the Si ROIC; depositing indium to fill the openings on both the IR detector array and the Si ROIC to create indium bumps, the indium bumps electrically connected to the contact areas of the IR detector array and the Si ROIC respectively, exposed on a top surface of the IR detector array and the Si ROIC; activating exposed dielectric layers on the IR detector array and the Si ROIC in a plasma; and closely contacting the indium bumps of the IR detector array and the Si ROIC by bonding together the exposed dielectric surfaces of the IR detector array and the Si ROIC.

Abstract: The present invention discloses a varifocal laser processing system and method based on a variable light spot diffractive element. The system includes a laser device for generating a laser, a collimating lens for changing a light path and a diffractive optical element module for controlling light spot focal point distribution. The laser emitted by the laser device passes through the collimating lens to irradiate the diffractive optical element module, and the laser focused by the diffractive optical element module irradiates a to-be-processed workpiece; and the diffractive optical element module includes at least two DOE lenses oppositely distributed in an axial direction and a rotary actuator driving the DOE lenses to rotate. The rotary actuator drives at least one DOE lens to rotate with a central axis as a rotating center, thereby changing a position of a focal point generated after the laser is focused by the diffractive optical element module.

Abstract: A device for correcting a forward head posture includes a front support configured to support a jaw of a user, a rear support configured to support a rear side of a cervical spine of the user, and an adjuster configured to adjust a distance between the front support and the rear support. As the adjuster is adjusted or operated, a lower jaw joint of the jaw of the user moves backward in a horizontal direction.

Abstract: Methods for treating a solid tumor, determined to lack a p53 deactivation mutation, in a subject are provided. Also provided are peptidomimetic macrocycles for use in treatment of a solid tumor, determined to lack a p53 deactivation mutation, in a subject.

Abstract: Provided are a method and apparatus for providing a counseling service. A method of operating a counseling center server interworking with an instant messaging service includes providing a profile of at least one expert account for counseling linked to a channel of a second user to a terminal of a first user, identifying an initiation condition for a counseling ticket for counseling with a first expert account, creating a counseling ticket to be allocated to the first expert account, and transmitting counseling content through a chat room for counseling of the channel in which the first expert account and an account of the first user participate.

Abstract: Provided are a method and apparatus for providing a counseling service. A method of operating a counseling center server interworking with an instant messaging service includes activating a connection with a chatbot server linked to a channel in a chat room, calling a chatbot block corresponding to a specific task included in the chatbot server through the chat room, transmitting a message received from a terminal of a user connected to the chat room to the chatbot server as an input of the chatbot block, and transmitting an output of the chatbot block in response to the message received from the chatbot server to the terminal of the user.

Abstract: Compositions and methods for editing, e.g., introducing double-stranded breaks, within the TTR gene are provided. Compositions and methods for treating subjects having amyloidosis associated with transthyretin (ATTR), are provided.

Abstract: Compositions and methods for editing, e.g., introducing double-stranded breaks, within the TTR gene in combination with administration of a corticosteroid are provided. Compositions and methods for treating subjects having amyloidosis associated with transthyretin (ATTR), in which a guide RNA and a corticosteroid are administered, are provided.

Abstract: Provided are a method and apparatus for providing a counseling service. A method of operating a counseling center server interworking with an instant messaging service includes acquiring, based a search request for a message transmitted to a channel registered in the service, a search result of a chatbot server linked to the channel, providing an interface for inputting a value of at least one parameter included in the search result to a terminal of a counselor linked to the channel, acquiring an entity corresponding to the parameter based on the message, determining a value of the parameter based on at least one of the acquired entity and data input through the interface, and requesting, based on the determined value of the parameter, an instant messaging server configured to provide the service to transmit a response message corresponding to the search result.