Abstract: The invention discloses a method for producing lysine by utilizing adsorption and immobilized fermentation of a recombinant Corynebacterium glutamicum, wherein the recombinant Corynebacterium glutamicum is constructed by simultaneously overexpressing an adenosine triphosphate ATPase while knocking out an extracellular nuclease ExeR in a Corynebacterium glutamicum. The recombinant Corynebacterium glutamicum can effectively improve eDNA secretion of the Corynebacterium glutamicum and reduce eDNA degradation of the Corynebacterium glutamicum, so that the Corynebacterium glutamicum can be more easily adsorbed on a surface of a solid carrier for immobilized fermentation, such that a yield of continuous immobilized fermentation of the Corynebacterium glutamicum is increased by 49.67% than that of free fermentation of an original bacterium, and a fermentation cycle is shortened by 29.17%.

Abstract: A connector is configured to connect a first electronic component and a second electronic component, and includes: an enclosure, where a through-hole is disposed on the enclosure; a pin assembly disposed in the enclosure, the pin assembly is movable relative to the enclosure; a flexible printed circuit board, where one end of the flexible printed circuit board is connected to the pin, and the other end is configured to be connected to a circuit board in the first electronic component; a plug structure configured to be detachably connected to the second electronic component; and a driving assembly, where when the second electronic component is connected to the plug structure, the driving assembly is able to drive the pin assembly to move relative to the enclosure in a direction close to the through-hole, so that the pin extends out of the through-hole and is connected to the second electronic component.

Abstract: The present application relates to a composition comprising the following components: A) at least one ethylene/alpha-olefin interpolymer; B) a peroxide; C) at least one filler selected from one or more carbon black samples, MgO, or a combination thereof; and optionally, at least one filler selected from silica, ZnO, CaCO3, A1 (OH)3, Mg (OH)2, or a combination thereof; D) a calculated P content from 0.010 wt % to 0.300 wt %, based on the weight of the composition, and wherein the calculated P content is the calculated content the phosphorus element present in one or more phosphate compounds selected from Structure 1 below: O?P (OR1) (OR2) (OR3) (Structure 1), wherein R1, R2 and R3 are each, independently, selected from i) a non-aromatic hydrocarbon or ii) a non-aromatic hydrocarbon comprising at least one heteroatom, excluding P.

Abstract: The present application discloses a 3D printing device and a release method and a liquid containing mechanism therefor, and relates to the field of 3D printing. The liquid containing mechanism comprises a material box foundation, a material box and a plurality of motion guide components. The material box foundation is a rigid annular plate with a mounting groove and is detachably mounted on a base of the 3D printing device, the mounting groove of the material box foundation is covered by a light-transmitting glass plate, and the glass plate is fixed on an upper surface of the material box foundation. The plurality of motion guide components are fixed to a peripheral edge of the material box and then detachably fixed on the material box foundation. Each of the motion guide components is a following component with an upper limit structure and a lower limit structure, and the following component is fixed to the peripheral edge of the material box.

Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).

Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).

Abstract: Disclosed are methods of isolating T cells having antigenic specificity for a mutated amino acid sequence encoded by a cancer-specific mutation, the method comprising: identifying one or more genes in the nucleic acid of a cancer cell of a patient, each gene containing a cancer-specific mutation that encodes a mutated amino acid sequence; inducing autologous APCs of the patient to present the mutated amino acid sequence; co-culturing autologous T cells of the patient with the autologous APCs that present the mutated amino acid sequence; and selecting the autologous T cells. Also disclosed are related methods of preparing a population of cells, populations of cells, pharmaceutical compositions, and methods of treating or preventing cancer.

Abstract: An orthodontic appliance may include an archwire and multiple orthodontic brackets. The archwire may fit within a human mouth and contain multiple male connectors. Each orthodontic bracket may have a configuration that facilitates attaching the orthodontic bracket to a single tooth. Each orthodontic bracket may allow one of the male connectors to be locked into the orthodontic bracket with a snapping action. The male connector may be unable to slide with respect to the orthodontic bracket after being locked in the orthodontic bracket. A manual unlocking action may allow the male connector to disengage from the orthodontic bracket.

Abstract: There is disclosed in one example a multi-core computing system configured to provide a hot-swappable CPU0, including: a first CPU in a first CPU socket and a second CPU in a second CPU socket; a switch including a first media interface to the first CPU socket and a second media interface to the second CPU socket; and one or more mediums including non-transitory instructions to detect a hot swap event of the first CPU, designate the second CPU as CPU0, determine that a new CPU has replaced the first CPU, operate the switch to communicatively couple the new CPU to a backup initialization code store via the first media interface, initialize the new CPU, and designate the new CPU as CPUN, wherein N?0.

Abstract: A method of fabricating a hollow-core photonic-bandgap fiber, comprising the steps of: providing a stack of capillaries, wherein the stack has a hollow core and the capillaries at a boundary of the core comprise a plurality of first, corner core capillaries and a plurality of second, intermediate core capillaries; applying a pressure differential between the corner core capillaries and the intermediate core capillaries, whereby a size of the corner core capillaries can be controlled in relation to the intermediate core capillaries; and reducing the stack to a fiber, wherein the fiber has a hollow core and a cladding which surrounds the core at a core boundary and comprises a lattice or network of struts and interstitial nodes which together define an array of cavities.

Abstract: A production method of a digitized artificial nail for a nail of a user includes the steps of: (a) scanning the nail of the user to construct an irregular digitized user nail model; (b) data sampling to convert the irregular digitized user nail model into a regular digitized artificial nail model which is a regular three dimensional grid surface, and topology deformation of the regular three dimensional grid surface to form a digitized artificial nail model; (c) matching an artificial nail shape selected by the user with the digitized artificial nail model to obtain a desired artificial nail model; (d) customizing the digitized artificial nail model; and (e) three dimensional printing a digitized artificial nail in response to the digitized artificial nail model.

Abstract: Provided are cell culture apparatus and method. The cell culture apparatus comprises a culture column and a perfusion system, the culture column comprising a first and a second tube-connecting caps and a support for cells to attach and grow thereon. The first and the second tube-connecting caps are respectively provided with a perfusion inlet and a perfusion outlet; The perfusion system comprises a culture medium storage device, a perfusion tube and a perfusion pump. A complete and closed culture column is formed in the cell culture device after the cells are inoculated, and the culturing is completed by the perfusion system to avoid contamination.

Abstract: The invention discloses a recombinant Corynebacterium glutamicum for producing lysine by biofilm continuous fermentation and a construction method thereof, wherein the recombinant Corynebacterium glutamicum is constructed by overexpressing a protease gene FtsH in a Corynebacterium glutamicum; and the construction method comprises the following steps of: (1) performing PCR on a genome of the Corynebacterium glutamicum, and amplifying the FtsH gene to obtain an amplified FtsH gene segment; (2) cloning the FtsH gene segment to an overexpression plasmid to obtain a recombinant plasmid; and (3) introducing the recombinant plasmid into the Corynebacterium glutamicum, and screening to obtain the recombinant Corynebacterium glutamicum.

Abstract: The invention discloses a method for producing lysine by utilizing adsorption and immobilized fermentation of a recombinant Corynebacterium glutamicum, wherein the recombinant Corynebacterium glutamicum is constructed by simultaneously overexpressing an adenosine triphosphate ATPase while knocking out an extracellular nuclease ExeR in a Corynebacterium glutamicum. The recombinant Corynebacterium glutamicum can effectively improve eDNA secretion of the Corynebacterium glutamicum and reduce eDNA degradation of the Corynebacterium glutamicum, so that the Corynebacterium glutamicum can be more easily adsorbed on a surface of a solid carrier for immobilized fermentation, such that a yield of continuous immobilized fermentation of the Corynebacterium glutamicum is increased by 49.67% than that of free fermentation of an original bacterium, and a fermentation cycle is shortened by 29.17%.

Abstract: The GNSS-RTK-based positioning method includes the following steps: Step 1, performing data quality control according to analyzed raw satellite-ground observation values; Step 2, performing SPP positioning by using a pseudorange observation value, and performing RTD positioning according to an RTD pseudorange residual of a previous epoch and a pseudorange residual of a current epoch obtained through SPP positioning calculation; Step 3, calculating a float solution by means of the least squares method and Kalman filtering of additional ambiguity parameters in which the RTD positioning result is used as an initial value; and Step 4, converting the float ambiguity solution into a fixed solution by using an optimized partial ambiguity fixing strategy.

Abstract: Provided is a method for producing a tissue-like construct having cultured cells organized in an aligned manner, especially, a cardiac tissue-like construct. The tissue-like construct prepared by this method is also provided. Further provided are a device for evaluating cellular electrophysiological functions and a method for evaluating cellular electrophysiological functions. Furthermore, a sheet-like cell culture scaffold is also provided.

Abstract: The present invention discloses an optical assembly. The optical assembly comprises: a first optical film comprising a first surface; an adhesive disposed on the first surface of the first optical film; and a second optical film comprising a second surface, wherein the second surface of the second optical film comprises a plurality of microstructures, wherein the plurality of microstructures are bonded to the adhesive; wherein the adhesive is made of a first material and the plurality of microstructures are made of a second material, wherein the hydrophilic/hydrophobic characteristic of the first material is configured with respect to the hydrophilic/hydrophobic characteristic of the second material such that the adhesive force between the adhesive and the plurality of microstructures of the second optical film is greater than 100 g/25 mm and the optical gain of the optical assembly is greater than 1.5.

Abstract: The present invention discloses a quantum-dot composite optical film comprising: a plurality of quantum dots dispersed in the optical film, wherein the plurality of quantum dots are capable of being water-resistant and oxygen-resistant; and a plurality of prisms, disposed over the quantum-dot layer.

Abstract: The present invention discloses a quantum-dot film, wherein the quantum-dot film comprises a binder and a plurality of quantum dots dispersed in the binder, wherein the plurality of quantum dots are capable of being water-resistant and oxygen-resistant.