Abstract: Described herein are compositions and methods useful to treat cancers. In addition, the present invention provides screening assays, diagnostic assays, methods to prognose, methods to treat, and kits.

Abstract: Disclosed herein is a multilayered film comprising a first layer and a second layer; and a tie layer; where the tie layer comprises a crystalline block composite and where the tie layer is disposed between the first layer and the second layer; the first layer being disposed on a first surface of the tie layer; the second layer being disposed on a second surface of the tie layer; where the second surface is opposedly disposed to the first surface; where the multilayered film is biaxially oriented. Disclosed herein too is a method of manufacturing the aforementioned multilayer film.

Abstract: A composite optical film has the functions of brightness enhancement, self-diffusion and defect blocking. The film comprises: a structured substrate including a structured light incidence surface and a light emitting surface opposite to the structured light incidence surface, wherein the structured light incidence surface includes longitudinal prism structures or longitudinal lens structures transversely arranged in rows; a support base plate adjacent to the light emitting surface of the structured substrate, the support base plate having a light incidence surface on one side and a light emitting surface on another side opposite to the light incidence surface, wherein at least one of the light incidence surface and the light emitting surface has a plurality of buried particles, and at least one portion of the buried particles are protruded on the light emitting surface of the support base plate.

Abstract: The present invention provides a microfluidic device comprising at least one cell culture chamber, the or each chamber being connected to at least two openings, the device being configured to supply at least one physiologically active substance from at least one of the openings to the or each cell culture chamber in such a manner as to form a concentration gradient or concentration gradients in the or each chamber when cells and a hydrogel are introduced into the or each chamber to culture the cells in a 3D-gel medium.

Abstract: Methods, systems, and apparatus including medium-encoded computer program products for performing additive manufacturing (AM) using continuous resin flow based mask video projection stereolithography (MVP-SL) According to an aspect, a system for additive manufacturing of an object in three dimensions consisting of an X dimension, a Y dimension, and a Z dimension, the system comprising: a tank configured to contain a liquid resin; a first translation stage coupled with the tank, the first translation stage being configured to move the tank in the X dimension, the Y dimension, or both; a second translation stage coupled with a build platform, the second translation stage being configured to move the build platform in the Z dimension; and a computer control system to cause the second translation stage to elevate the build platform in the Z dimension simultaneously with causing the first translation stage to perform the sliding motion.

Abstract: A method for preparing methacrolein from t-butanol, specifically a method for preparing methacrolein by using t-butanol as a starting material, is disclosed, comprising passing the starting material through a fixed bed reactor filled with catalyst, wherein the fixed bed reactor is divided to n reaction zones from the inlet of the starting material to the outlet of the starting material and each zone is filled with catalysts of different catalytic activities; wherein the catalytic activity of the catalyst in the first reaction zone is higher than the catalytic activity of the catalyst in the second reaction zone, and the catalytic activity of the catalyst is gradually increased from the second reaction zone to the last reaction zone; and n is an integer between 3 to 10.

Abstract: An orthodontic appliance may include an archwire and multiple orthodontic brackets. The archwire may fit within a human mouth and contain multiple male connectors. Each orthodontic bracket may have a configuration that facilitates attaching the orthodontic bracket to a single tooth. Each orthodontic bracket may allow one of the male connectors to be locked into the orthodontic bracket with a snapping action. The male connector may be unable to slide with respect to the orthodontic bracket after being locked in the orthodontic bracket. A manual unlocking action may allow the male connector to disengage from the orthodontic bracket.

Abstract: An orthodontic appliance may include an archwire and multiple orthodontic brackets. The archwire may fit within a human mouth and contain multiple male connectors. Each orthodontic bracket may have a configuration that facilitates attaching the orthodontic bracket to a single tooth. Each orthodontic bracket may allow one of the male connectors to be locked into the orthodontic bracket with a snapping action. The male connector may be unable to slide with respect to the orthodontic bracket after being locked in the orthodontic bracket. A manual unlocking action may allow the male connector to disengage from the orthodontic bracket.

Abstract: It discloses a use of N-acetylneuraminic acid aldolase with an amino acid sequence as shown in SEQ ID NO: 2 in catalytic synthesis of N-acetylneuraminic acid. The preparation of N-acetylneuraminic acid is to use the N-acetylneuraminic acid aldolase with the amino acid sequence as shown in SEQ ID NO: 2 as a catalyst, and N-acetylmannosamine and pyruvic acid as substrates.

Abstract: A method and apparatus for starting an application in a screen-locked state, used for an electronic device, said method comprising: detecting whether the device is in a screen-locked state; receiving a slide operation command directed at the icon of an application to be started; if the slide operation directed at said application icon satisfies a first preset condition, providing memory resources to start the application to be started; if the slide operation directed at said application icon satisfies a second preset condition, performing a screen unlock operation and starting the application to be started. The method and apparatus facilitate a user starting an application in a screen-locked state, and increase speed when starting the application and improve user experience.

Abstract: A solid imaging apparatus and method employing levels of exposure varied with gray scale or time or both of digitally light projected image of a cross-section of a three-dimensional object on a solidifiable photopolymer build material. The gray scale levels of exposure of projected pixels permits the polymerization boundaries in projected boundary pixels to be controlled to achieve preserved image features in a three-dimensional object and smooth out rough or uneven edges that would otherwise occur using digital light projectors that are limited by the number of pixels in an image projected over the size of the image. Software is used to control intensity parameters applied to pixels to be illuminated in the image projected in the cross-section being exposed in the image plane.

Abstract: Various embodiments provide transistors and methods for forming the same. In an exemplary method, a substrate is provided, having a dummy gate structure including a dummy gate dielectric layer on the substrate and a dummy gate layer on the dummy gate dielectric layer. A dielectric layer is formed on the substrate and on sidewall surfaces of the dummy gate structure. A top surface of the dielectric layer is leveled with a top surface of the dummy gate structure. A barrier layer is formed on the dielectric layer for protecting the dielectric layer. The dummy gate layer and the dummy gate dielectric layer are removed, to form an opening in the dielectric layer without reducing a thickness of the dielectric layer. A gate dielectric layer is formed on sidewall surfaces and a bottom surface of the opening. A gate layer is formed on the gate dielectric layer to fill the opening.

Abstract: A microelectronic assembly can include an address bus comprising a plurality of signal conductors each passing sequentially through first, second, third, and fourth connection regions, and first and second microelectronic packages. The first microelectronic package can include first and second microelectronic elements, and the second microelectronic package can include third and fourth microelectronic elements. Each microelectronic element can be electrically coupled to the address bus via the respective connection region. An electrical characteristic between the first and second connection regions can be within a same tolerance of the electrical characteristic between the second and third connection regions.

Abstract: Disclosed is a method for a mobile user to access a fixed network, comprising: after a BNG and a TWAG establish a multi-protocol label switching (MPLS) tunnel and/or pseudowire, or a layer 2 tunneling protocol (L2TP) tunnel and/or session, the TWAG establishes a GPRS tunneling protocol (GTP)/proxy mobile internet protocol (PMIP) connection with a mobile network gateway according to user information, and acquires the address and service parameter of the user; and the TWAG transmits the service parameter of the user to the BNG via an MPLS control message or an L2TP control message. Also disclosed is a system for a mobile user to access a fixed network. The present invention standardizes user QoS security after the introduction of a TWAG, and can provide a user with better communication service, thus improving user experience.

Abstract: There is provided a method for displaying a router setup interface. The method is performed by a terminal and includes: receiving broadcast information from a wireless router; acquiring configuration parameters contained in the broadcast information; determining, based on the configuration parameters, whether an initialization setup of the wireless router is completed; if it is determined that the initialization setup of the wireless router is not completed, establishing a connection with the wireless router; acquiring a setup interface of the wireless router through the connection; and displaying the setup interface.

Abstract: The present disclosure describes systems and techniques relating to computer numerical control (CNC) additive manufacturing. According to an aspect, a tooltip for an additive manufacturing machine includes: an input end configured to receive light from an optical system; and an output end configured to deliver the light to a workpiece on a build platform in the additive manufacturing machine; wherein the output end of the tooltip is configured to be immersed in a liquid resin in a tank of the additive manufacturing machine, and the output end defines a linear opening through which the light is delivered to the workpiece on the build platform.

Abstract: The present disclosure proposes a method of synchronously playing media file. The method includes: receiving, with a mobile terminal, parameter information from a playing device, the parameter information including a current playing progress and a total time length of a current playing media file; starting to count time, with the mobile terminal, upon receiving the parameter information and calculating, with the mobile terminal, a real-time playing progress of the media file based on a predetermined time interval according to the parameter information and timing information; displaying, with the mobile terminal, the real-time playing progress on a display interface. The present disclosure solves unstable data transmission and enhances the accuracy of displaying progress of the playing device.

Abstract: A dry-wet combined sorting system for municipal solid waste comprising a dry type smashing and winnowing device and a wet type water sorting device. The system is compact in structure; smashing knives with different revolving speeds and the same revolving direction are provided, thereby enabling continuous processing of the system which is high in processing efficiency and simple in operation; meanwhile, multiple protection devices are provided, so that the whole system is safe and reliable; perishable organic matters, light combustible matters and inorganic matters can be separated completely; the light combustible matters are picked out by the dry type smashing and winnowing device, which ensures their low water content and facilitates their subsequent energy-oriented utilization. Therefore, the municipal solid waste is into valuable thing for it can be utilized sufficiently as a resource, and the system has very high environmental benefits and social benefits.

Abstract: A microelectronic package can include a support element having first and second surfaces and substrate contacts at the first or second surface, zeroth and first stacked microelectronic elements electrically coupled with the substrate contacts, and terminals at the second surface electrically coupled with the microelectronic elements. The second surface can have a southwest region encompassing entire lengths of south and west edges of the second surface and extending in orthogonal directions from the south and west edges one-third of each distance toward north and east edges of the second surface, respectively. The terminals can include first terminals at a southwest region of the second surface, the first terminals configured to carry address information usable by circuitry within the microelectronic package to determine an addressable memory location from among all the available addressable memory locations of the memory storage arrays of at least one of the zeroth or first microelectronic elements.

Abstract: Example embodiments associated with characterizing a sample using NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. The NMR signals are produced in response to a FISP-MRF pulse sequence. Sampling is performed with t and/or E varying in a non-constant way. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals and a characterization logic that characterizes a tissue in the object as a result of comparing acquired signals to reference signals. Acquired signals are corrected using data describing an inhomogeneous B1 field produced by the NMR apparatus while the set of NMR signals are acquired.