Abstract: Among the various aspects of the present disclosure is the provision of a blood brain barrier (BBB) opening agent and uses thereof. An aspect of the present disclosure provides for methods of opening up the BBB; increasing the permeability of the tricellular junction; and using a BBB opening agent for the treatment of a brain pathology or neurological disease, disorder, or condition.

Abstract: A Schmitt trigger circuit having an input coupled to a current summing junction. A trickle current source generates a trickle current applied to the current summing junction. A bandgap current source generates a bandgap current applied to the current summing junction (wherein the bandgap current is fixed when a supply voltage exceeds a threshold). A variable current source generates a variable current applied to the current summing junction (wherein the variable current varies dependent on the supply voltage). At the current summing junction, the variable current is offset against the trickle and bandgap currents with respect to generating a voltage that is sensed at the Schmitt trigger circuit input.

Abstract: An impedance matching circuit is provided for use with a piezotransducer that includes a parasitic capacitor comprising: an inductor coupled in parallel with the parasitic capacitor; a peak and valley detection circuit configured to detect output voltage waveform peaks and valleys; a first switch circuit configured to bias flip the output voltage waveform at a selectable first time relative to a detected peak and at a selectable first time relative to a detected valley; a second switch circuit configured to couple the inductor to the energy storage circuit at a selectable second time following each output voltage bias flip; an energy monitoring circuit to provide an indication of energy flow from the inductor to the energy storage circuit following each output voltage bias flip; and a maximum power point tracking (MPPT) circuit configured to select the first time and the second time based at least in part upon the indicated energy flow.

Abstract: An electronic circuit can be coupled to an energy harvesting device. The output of the energy harvesting device can provide a damped oscillating waveform elicited from a transient stimulus applied to the energy harvesting device, such as in response to mechanical shock or mechanical impact excitation. A first switch can be coupled between the energy harvesting device and an inductor and configured to selectively connect the input node to the inductor. A second switch can be coupled between the inductor and an energy storage device, the second switch configured to selectively couple the inductor to the energy storage device. A control circuit can be coupled to the first and second switches, such as configured to operate the first and second switches according to one or more of an over bias flip technique, a half bias flip technique, or a bias flip technique.

Abstract: Embodiments include a technique for predictive virtual server scheduling and optimization of dynamic consumable resources to achieve priority-based workload performance objectives is provided. Techniques include calculating a capacity requirement for each virtual server based on an administrator defined performance objective for each virtual server. Techniques also include calculating an available CPU capacity for each importance level based on the calculated capacity requirement for each virtual server, sending the calculated available CPU capacity to a scheduler; and selecting a target hypervisor based on the calculated capacity requirement of each virtual server and the calculated available CPU capacity at each importance level of each hypervisor.

Abstract: Embodiments include a technique for predictive virtual server scheduling and optimization of dynamic consumable resources to achieve priority-based workload performance objectives is provided. Techniques include calculating a capacity requirement for each virtual server based on an administrator defined performance objective for each virtual server. Techniques also include calculating an available CPU capacity for each importance level based on the calculated capacity requirement for each virtual server, sending the calculated available CPU capacity to a scheduler; and selecting a target hypervisor based on the calculated capacity requirement of each virtual server and the calculated available CPU capacity at each importance level of each hypervisor.

Abstract: A voltage regulator includes a feedback regulation loop and a drive transistor configured to source current to a regulated output. A transient recovery circuit is coupled to the voltage regulator circuit and includes a first transistor coupled to source current into a control terminal of the drive transistor, wherein the source current is in addition to current sourced in response to operation of the feedback regulation loop. The first transistor is selectively actuated in response to a drop in voltage at the regulated output. The transient recovery circuit further includes a second transistor coupled to sink current from the regulated output. The sink current has a first non-zero magnitude in the quiescent operating mode of the regulator circuit. In response to an increase in voltage at the regulated output, the operation of the second transistor is modified to increase the sink current to a second, greater, non-zero magnitude.

Abstract: Pre-processing before precise pattern matching of a target pattern from a stream of patterns. Including acquiring occurrence numbers of target elements in the target pattern, initializing the buffer, the buffer indicating a section in the stream of patterns, determining whether occurrence numbers of the target elements in the buffer reach the occurrence numbers of the target elements in the target pattern, updating the buffer and then returning to the determining step, in response to determining that the occurrence numbers of the target elements in the buffer do not reach the occurrence numbers of the target elements in the target pattern, and outputting the elements in the buffer for subsequent processing, in response to determining that the occurrence numbers of the target elements in the buffer reach the occurrence numbers of the target elements in the target pattern.

Abstract: Pre-processing before precise pattern matching of a target pattern from a stream of patterns. Including acquiring occurrence numbers of target elements in the target pattern, initializing the buffer, the buffer indicating a section in the stream of patterns, determining whether occurrence numbers of the target elements in the buffer reach the occurrence numbers of the target elements in the target pattern, updating the buffer and then returning to the determining step, in response to determining that the occurrence numbers of the target elements in the buffer do not reach the occurrence numbers of the target elements in the target pattern, and outputting the elements in the buffer for subsequent processing, in response to determining that the occurrence numbers of the target elements in the buffer reach the occurrence numbers of the target elements in the target pattern.

Abstract: A medication dispenser includes a base seat, a circuitry unit and an outer casing. The base seat includes a mouthpiece. The circuitry unit includes a first circuit board, a battery, and first and second switches disposed on the first circuit board. The outer casing is movable relative to the base seat between a close position where the outer casing covers the mouthpiece and where the first switch is actuated such that electric power is prevented from being supplied from the battery to the first circuit board, and an open position where the outer casing uncovers the mouthpiece and where the second switch is actuated such that electric power is supplied from the battery to the first circuit board.

Abstract: A method for pattern matching finds a target pattern from a stream of patterns, both of the stream of patterns and the target pattern being comprised of elements. The method includes acquiring occurrence numbers of target elements in the target pattern, initializing the buffer, the buffer indicating a section in the stream of patterns, determining whether occurrence numbers of the target elements in the buffer reach the occurrence numbers of the target elements in the target pattern, updating the buffer and then returning to the determining step, in response to determining that the occurrence numbers of the target elements in the buffer do not reach the occurrence numbers of the target elements in the target pattern, and outputting the elements in the buffer for subsequent processing, in response to determining that the occurrence numbers of the target elements in the buffer reach the occurrence numbers of the target elements in the target pattern.

Abstract: Placement of virtual machines on physical hosts are based on differing initial policies and optimization policies set by a system administrator to more efficiently utilize system resources and serve the needs of different workloads. A scheduler mechanism allows a system administrator to select different initial placement policies for one or more host groups of physical hosts. The scheduler mechanism utilizes an optimizer that monitors host performance and adjusts the placement of virtual machines according to another set of optimization policies similarly selected by the system administrator for each of the host groups.

Abstract: Pre-processing before precise pattern matching of a target pattern from a stream of patterns. Including acquiring occurrence numbers of target elements in the target pattern, initializing the buffer, the buffer indicating a section in the stream of patterns, determining whether occurrence numbers of the target elements in the buffer reach the occurrence numbers of the target elements in the target pattern, updating the buffer and then returning to the determining step, in response to determining that the occurrence numbers of the target elements in the buffer do not reach the occurrence numbers of the target elements in the target pattern, and outputting the elements in the buffer for subsequent processing, in response to determining that the occurrence numbers of the target elements in the buffer reach the occurrence numbers of the target elements in the target pattern.

Abstract: Placement of virtual machines on physical hosts are based on differing initial policies and optimization policies set by a system administrator to more efficiently utilize system resources and serve the needs of different workloads. A scheduler mechanism allows a system administrator to select different initial placement policies for one or more host groups of physical hosts. The scheduler mechanism utilizes an optimizer that monitors host performance and adjusts the placement of virtual machines according to another set of optimization policies similarly selected by the system administrator for each of the host groups.

Abstract: The invention relates to a method for refining a feed oil having contaminants therein. In the method, the feed oil is exposed to reducing conditions at elevated temperature and pressure so as to reduce at least some of said contaminants. The resulting oil is then degassed under reduced pressure under non-oxidizing conditions and the resulting oil extracted with water so as to produce a refined oil.

Abstract: A Schmitt trigger circuit having an input coupled to a current summing junction. A trickle current source generates a trickle current applied to the current summing junction. A bandgap current source generates a bandgap current applied to the current summing junction (wherein the bandgap current is fixed when a supply voltage exceeds a threshold). A variable current source generates a variable current applied to the current summing junction (wherein the variable current varies dependent on the supply voltage). At the current summing junction, the variable current is offset against the trickle and bandgap currents with respect to generating a voltage that is sensed at the Schmitt trigger circuit input.

Abstract: Adjusting the layout size of a hyperlink includes displaying at least one hyperlink in a user interface; detecting a touch operation for the at least one hyperlink, and extracting position coordinates of a touch point formed by the touch operation on the user interface. Adjusting the layout size further includes determining a target hyperlink from the at least one hyperlink, and determining the precision of the touch operation with respect to the target hyperlink based on the position coordinates of the touch point; and adjusting layout size of the target hyperlink based on the determined precision. The hyperlink layout in a web page can be adapted to the touch precision of user's finger automatically, which facilitates the recognition of hyperlinks by the user's finger.

Abstract: Placement of virtual machines on physical hosts are based on differing initial policies and optimization policies set by a system administrator to more efficiently utilize system resources and serve the needs of different workloads. A scheduler mechanism allows a system administrator to select different initial placement policies for one or more host groups of physical hosts. The scheduler mechanism utilizes an optimizer that monitors host performance and adjusts the placement of virtual machines according to another set of optimization policies similarly selected by the system administrator for each of the host groups.

Abstract: A Schmitt trigger circuit having an input coupled to a current summing junction. A trickle current source generates a trickle current applied to the current summing junction. A bandgap current source generates a bandgap current applied to the current summing junction (wherein the bandgap current is fixed when a supply voltage exceeds a threshold). A variable current source generates a variable current applied to the current summing junction (wherein the variable current varies dependent on the supply voltage). At the current summing junction, the variable current is offset against the trickle and bandgap currents with respect to generating a voltage that is sensed at the Schmitt trigger circuit input.

Abstract: A probe insertion auxiliary and a method of probe insertion are provided. A light source illuminates holes on a lower die to make the position of the holes clear for an operator. The probe insertion auxiliary includes a bottom and a clamp pair disposed on the bottom. The clamp pair has two clamp parts. The two clamp parts define a slit for disposing a probe chassis. Furthermore, the two clamp parts and the bottom form a space. A light source is disposed inside the space for illuminating the holes.